The Brain derived neurotrophic factor (BDNF) is critically involved in neuroplasticity as well as... more The Brain derived neurotrophic factor (BDNF) is critically involved in neuroplasticity as well as the acquisition, consolidation, and retention of hippocampal-and amygdala-dependent learning. A common functional A→G single nucleotide polymorphism (BDNFval66met) in the pro-domain of the human BDNF gene is associated with abnormal intracellular trafficking and reduced activitydependent BDNF release. We studied the effect of BDNFval66met in an aversive differential fear conditioning, and a delayed extinction paradigm in fifty-seven healthy participants. Pictures of male faces were used as stimuli and fear learning was quantified by fear potentiated startle (FPS) and skin conductance responses (SCR).
The Brain derived neurotrophic factor (BDNF) is critically involved in neuroplasticity as well as... more The Brain derived neurotrophic factor (BDNF) is critically involved in neuroplasticity as well as the acquisition, consolidation, and retention of hippocampal-and amygdala-dependent learning. A common functional A→G single nucleotide polymorphism (BDNFval66met) in the pro-domain of the human BDNF gene is associated with abnormal intracellular trafficking and reduced activitydependent BDNF release. We studied the effect of BDNFval66met in an aversive differential fear conditioning, and a delayed extinction paradigm in fifty-seven healthy participants. Pictures of male faces were used as stimuli and fear learning was quantified by fear potentiated startle (FPS) and skin conductance responses (SCR).
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Papers by Armita Golkar