Childhood epilepsy is a prevalent neurological disorder. Imaging, especially MRI of the brain, pl... more Childhood epilepsy is a prevalent neurological disorder. Imaging, especially MRI of the brain, plays a pivotal role in diagnosing the underlying cause. This study aimed to assess the frequency of causative factors of epilepsy detected in MRI. This hospital-based prospective observational study was conducted in the Radiology Department at Rajendra Institute of Medical Sciences (RIMS), Ranchi, Jharkhand, India from November 2021 to October 2022 in 100 children of 0 to 12 years of age referred from Pediatrics department for an MRI brain scan. MRI of the brain was performed in all cases and findings were analyzed and causes of epilepsy were assessed. Magnetic resonance spectroscopy (MRS) was also done when required for confirmation of diagnosis. Positive findings in MRI were detected in 87% of children, and no abnormalities were detected in 13%. The majority of children belonged to the age group of 10-12 years (37%) and were predominantly males (66%). The most common cause of epilepsy was infections (27%) followed by hypoxic ischemic encephalopathy (22%). Tuberculoma was the most common infective cause of epilepsy in 59.3%. These were further followed by temporal lobe epilepsy and congenital malformations (11% each). The rest were other miscellaneous and idiopathic causes. MRI findings were specific to various conditions, helping in the localization and characterization of etiologies and playing a significant role in the evaluation of children who were newly diagnosed with epilepsy, especially those with partial seizures. Recommendation: Further research with a larger sample size and meta-analysis is recommended for more conclusive results.
Background Hypertensive disorders are one of the most common complications of pregnancy. This stu... more Background Hypertensive disorders are one of the most common complications of pregnancy. This study aimed to investigate the relationship between ophthalmic artery Doppler indices and preeclampsia development and evaluate differences in these indices between normotensive and hypertensive pregnancies. Methods A hospital-based cross-sectional observational study was conducted involving a sample size of 80 pregnant women: 40 normotensive and 40 preeclamptic. The participants' ophthalmic artery Doppler parameters were evaluated using ultrasonography. Various clinical and demographic factors were also collected for analysis. Results Significant differences in the pulsatility index (PI) and end-diastolic volume (EDV) of the ophthalmic arteries were found between the normotensive and preeclamptic participants (p < 0.05). An inverse correlation was observed between the ophthalmic artery PI (OAPI) and mean maternal arterial pressure, suggesting reduced orbital vascular resistance and increased orbital flow. Moreover, the decrease in PI was more significant in severely preeclamptic women than in mildly preeclamptic and normotensive women. The findings indicated a significant correlation between ophthalmic artery Doppler parameters and the development of preeclampsia. The decrease in OAPI was particularly profound in women with severe preeclampsia. However, the study was limited by its small sample size and the lack of matching of participants based on maternal age, gestational age, and other factors. Conclusions The study results suggest that ophthalmic artery Doppler parameters, mainly PI and EDV, could serve as reliable indicators for the development of preeclampsia. Given their safety, cost-effectiveness, and accessibility, these parameters can help differentiate between preeclamptic and normotensive pregnancies in late gestation. Further research with larger sample sizes and matched participant groups is recommended for more conclusive results.
International journal of scientific research, 2019
AIMS: Cross sectional observational comparative study in a tertiary care hospital on Relation bet... more AIMS: Cross sectional observational comparative study in a tertiary care hospital on Relation between Ischemic Heart Disease among Physically Active Tribal's of Jharkhand presenting with chest discomfort. MATERIAL AND METHODS: 102 physically active Tribal subjects (53 male and 49 female) were selected for the study, who had presented with chest discomfort. RESULTS: The incidence of I.H.D. is 1.41% among tribal population of Jharkhand. The incidence was found exclusively in tribal female living in urban area mostly due to adopting sedentary pattern of life style. CONCLUSION: The tribal population of Jharkhand has inversely proportional relation to Ischemic Heart Disease and physical activity.
Title: : CSF lactic acid estimation in meningitis Aims: The aim of present study was to determine... more Title: : CSF lactic acid estimation in meningitis Aims: The aim of present study was to determine the association of cerebrospinal fluid lactic acid estimation among patients of meningitis. Materials and Methods: This cross sectional, observational study consisted of 32 patients of pyogenic meningitis, 30 patients of viral meningitis and 30 control patients without meningitis patients, assessed with CSF cytology and biochemistry specifically CSF sugar, protein and lactic acid estimation on day 1 and day 8. Results: Overall meningitis was characterized by higher CSF cell counts and lactic acid but lower sugar and protein measurements. While differentiating between pyogenic and viral meningitis low sugar and high cell counts and lactic acid characterized pyogenic in day one estimations, however lactate remained most relevant in differentiations on day 8. Conclusions: The study found that CSF lactic acid estimation differentiates the viral and pyogenic meningitis over eight days, more ...
TITLE- “Prevalence of Alcoholism among tribals of Jharkhand with Chest discomfort”. AIMS: Cross s... more TITLE- “Prevalence of Alcoholism among tribals of Jharkhand with Chest discomfort”. AIMS: Cross sectional observational comparative study in a tertiary care hospital on “Prevalence of Alcoholism among tribals of Jharkhand with Chest discomfort”. MATERIAL AND METHODS: 102 tribal subjects (53 male and 49 female) from Jharkhand, India were selected for the study, who had presented with chest discomfort with history of alcoholism. RESULTS: The prevalence rate of Alcoholism among tribal males, 71.69% were moderate drinkers, 18.86% were heavy drinkers. Whereas among tribal females 57.14% were moderate drinkers and 10.20% were heavy drinkers. CONCLUSION: The prevalence of Alcoholism among tribal patients of chest discomfort was found to be 50% and 39.21% among male and female tribal’s of Jharkhand, India respectively.
International Journal of Research in Medical Sciences
Background: Cross sectional observational comparative study in a tertiary care hospital on Preval... more Background: Cross sectional observational comparative study in a tertiary care hospital on Prevalence of Hypertension among tribals of Jharkhand with Chest discomfort.Methods: 102 subjects (53 male and 49 female) were selected for the study, who had presented with chest discomfort and history of Hypertension.Results: In the current study total 102 subjects were taken, 53 were males. Among tribal males prevalence rate of hypertension, using (J.N.C.-7) criteria majority of them (41subjects 77.35%) were Prehypertensive. 8 subjects (15.09%) had normal blood pressure, 3 subjects (5.66%) had stage -I hypertension and only 1 subject (1.88%) had stage-2 hypertension. In females out of 49 subjects 28 subjects (57.14%) were pre hypertensive, 17 subjects (34.69%) were Normotensive and only 2 subjects (4.08 %) had stage -1 hypertension, as well as 2 subjects (4.08 %) had stage-2 hypertension.Conclusions: The prevalence of Hypertension among tribal patients of chest discomfort was found to be pr...
Childhood epilepsy is a prevalent neurological disorder. Imaging, especially MRI of the brain, pl... more Childhood epilepsy is a prevalent neurological disorder. Imaging, especially MRI of the brain, plays a pivotal role in diagnosing the underlying cause. This study aimed to assess the frequency of causative factors of epilepsy detected in MRI. This hospital-based prospective observational study was conducted in the Radiology Department at Rajendra Institute of Medical Sciences (RIMS), Ranchi, Jharkhand, India from November 2021 to October 2022 in 100 children of 0 to 12 years of age referred from Pediatrics department for an MRI brain scan. MRI of the brain was performed in all cases and findings were analyzed and causes of epilepsy were assessed. Magnetic resonance spectroscopy (MRS) was also done when required for confirmation of diagnosis. Positive findings in MRI were detected in 87% of children, and no abnormalities were detected in 13%. The majority of children belonged to the age group of 10-12 years (37%) and were predominantly males (66%). The most common cause of epilepsy was infections (27%) followed by hypoxic ischemic encephalopathy (22%). Tuberculoma was the most common infective cause of epilepsy in 59.3%. These were further followed by temporal lobe epilepsy and congenital malformations (11% each). The rest were other miscellaneous and idiopathic causes. MRI findings were specific to various conditions, helping in the localization and characterization of etiologies and playing a significant role in the evaluation of children who were newly diagnosed with epilepsy, especially those with partial seizures. Recommendation: Further research with a larger sample size and meta-analysis is recommended for more conclusive results.
Background Hypertensive disorders are one of the most common complications of pregnancy. This stu... more Background Hypertensive disorders are one of the most common complications of pregnancy. This study aimed to investigate the relationship between ophthalmic artery Doppler indices and preeclampsia development and evaluate differences in these indices between normotensive and hypertensive pregnancies. Methods A hospital-based cross-sectional observational study was conducted involving a sample size of 80 pregnant women: 40 normotensive and 40 preeclamptic. The participants' ophthalmic artery Doppler parameters were evaluated using ultrasonography. Various clinical and demographic factors were also collected for analysis. Results Significant differences in the pulsatility index (PI) and end-diastolic volume (EDV) of the ophthalmic arteries were found between the normotensive and preeclamptic participants (p < 0.05). An inverse correlation was observed between the ophthalmic artery PI (OAPI) and mean maternal arterial pressure, suggesting reduced orbital vascular resistance and increased orbital flow. Moreover, the decrease in PI was more significant in severely preeclamptic women than in mildly preeclamptic and normotensive women. The findings indicated a significant correlation between ophthalmic artery Doppler parameters and the development of preeclampsia. The decrease in OAPI was particularly profound in women with severe preeclampsia. However, the study was limited by its small sample size and the lack of matching of participants based on maternal age, gestational age, and other factors. Conclusions The study results suggest that ophthalmic artery Doppler parameters, mainly PI and EDV, could serve as reliable indicators for the development of preeclampsia. Given their safety, cost-effectiveness, and accessibility, these parameters can help differentiate between preeclamptic and normotensive pregnancies in late gestation. Further research with larger sample sizes and matched participant groups is recommended for more conclusive results.
International journal of scientific research, 2019
AIMS: Cross sectional observational comparative study in a tertiary care hospital on Relation bet... more AIMS: Cross sectional observational comparative study in a tertiary care hospital on Relation between Ischemic Heart Disease among Physically Active Tribal's of Jharkhand presenting with chest discomfort. MATERIAL AND METHODS: 102 physically active Tribal subjects (53 male and 49 female) were selected for the study, who had presented with chest discomfort. RESULTS: The incidence of I.H.D. is 1.41% among tribal population of Jharkhand. The incidence was found exclusively in tribal female living in urban area mostly due to adopting sedentary pattern of life style. CONCLUSION: The tribal population of Jharkhand has inversely proportional relation to Ischemic Heart Disease and physical activity.
Title: : CSF lactic acid estimation in meningitis Aims: The aim of present study was to determine... more Title: : CSF lactic acid estimation in meningitis Aims: The aim of present study was to determine the association of cerebrospinal fluid lactic acid estimation among patients of meningitis. Materials and Methods: This cross sectional, observational study consisted of 32 patients of pyogenic meningitis, 30 patients of viral meningitis and 30 control patients without meningitis patients, assessed with CSF cytology and biochemistry specifically CSF sugar, protein and lactic acid estimation on day 1 and day 8. Results: Overall meningitis was characterized by higher CSF cell counts and lactic acid but lower sugar and protein measurements. While differentiating between pyogenic and viral meningitis low sugar and high cell counts and lactic acid characterized pyogenic in day one estimations, however lactate remained most relevant in differentiations on day 8. Conclusions: The study found that CSF lactic acid estimation differentiates the viral and pyogenic meningitis over eight days, more ...
TITLE- “Prevalence of Alcoholism among tribals of Jharkhand with Chest discomfort”. AIMS: Cross s... more TITLE- “Prevalence of Alcoholism among tribals of Jharkhand with Chest discomfort”. AIMS: Cross sectional observational comparative study in a tertiary care hospital on “Prevalence of Alcoholism among tribals of Jharkhand with Chest discomfort”. MATERIAL AND METHODS: 102 tribal subjects (53 male and 49 female) from Jharkhand, India were selected for the study, who had presented with chest discomfort with history of alcoholism. RESULTS: The prevalence rate of Alcoholism among tribal males, 71.69% were moderate drinkers, 18.86% were heavy drinkers. Whereas among tribal females 57.14% were moderate drinkers and 10.20% were heavy drinkers. CONCLUSION: The prevalence of Alcoholism among tribal patients of chest discomfort was found to be 50% and 39.21% among male and female tribal’s of Jharkhand, India respectively.
International Journal of Research in Medical Sciences
Background: Cross sectional observational comparative study in a tertiary care hospital on Preval... more Background: Cross sectional observational comparative study in a tertiary care hospital on Prevalence of Hypertension among tribals of Jharkhand with Chest discomfort.Methods: 102 subjects (53 male and 49 female) were selected for the study, who had presented with chest discomfort and history of Hypertension.Results: In the current study total 102 subjects were taken, 53 were males. Among tribal males prevalence rate of hypertension, using (J.N.C.-7) criteria majority of them (41subjects 77.35%) were Prehypertensive. 8 subjects (15.09%) had normal blood pressure, 3 subjects (5.66%) had stage -I hypertension and only 1 subject (1.88%) had stage-2 hypertension. In females out of 49 subjects 28 subjects (57.14%) were pre hypertensive, 17 subjects (34.69%) were Normotensive and only 2 subjects (4.08 %) had stage -1 hypertension, as well as 2 subjects (4.08 %) had stage-2 hypertension.Conclusions: The prevalence of Hypertension among tribal patients of chest discomfort was found to be pr...
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