Conference Presentations by Anil Gumber
22ND SHAUKAT KHANUM CANCER SYMPOSIUM, 2023
Objectives: Depression and anxiety in breast cancer patients and survivors imposes huge costs to ... more Objectives: Depression and anxiety in breast cancer patients and survivors imposes huge costs to patients, survivors, families and healthcare system. Pakistan has the highest rates of breast cancer in Asia, with high prevalence of comorbid depression and anxiety. Reducing symptoms of psychological comorbidity has the potential to reduce cost by improving health-related quality of life of survivors. This is the secondary analysis of a randomized controlled trial to assess cost –effectiveness of an integrated psychological intervention to reduce depression and/or anxiety among breast cancer survivor.
Methods: Eligible consented participants, recruited from participating hospitals and community centres in Pakistan, were assessed at baseline, 4 and 6- month post-randomization. Participants in the intervention arm received 12 sessions over 4 months. Client Service Receipt Inventory was used to record health service utilization and EQ-5D-3L to measure health related quality adjusted life years (QALYs).
Results: Participants (n=354) were randomized (1:1) into Moving on ABC Plus or Treatment as Usual (TAU) arm. Total QALY gained in the intervention arm was 0.47 compared to 0.34 in TAU arm at 4-month post-randomization. Country specific unit cost was multiplied with resource used to get per person cost. The difference in costs per participant between intervention and TAU arms was 31873PKR (US$113). The Incremental Cost Effectiveness Ratio (ICER) was calculated based on between-arm differences in estimated cost and QALYs gains in the sampled population. The ICER for the intervention versus TAU was 243138PKR (US$859)/QALY gain. The intervention proved to be cost-effective with significantly lower ICER compared to threshold recommended by the WHO (i.e. 4515 = 3 x GDP Per Capita).
Conclusion: Results highlighted that the Moving on ABC plus intervention is cost-effective compared to TAU. These findings suggest that implementing culturally relevant and management intervention for comorbid mental health problems may lead to significant societal cost savings.
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Conference Presentations by Anil Gumber
Methods: Eligible consented participants, recruited from participating hospitals and community centres in Pakistan, were assessed at baseline, 4 and 6- month post-randomization. Participants in the intervention arm received 12 sessions over 4 months. Client Service Receipt Inventory was used to record health service utilization and EQ-5D-3L to measure health related quality adjusted life years (QALYs).
Results: Participants (n=354) were randomized (1:1) into Moving on ABC Plus or Treatment as Usual (TAU) arm. Total QALY gained in the intervention arm was 0.47 compared to 0.34 in TAU arm at 4-month post-randomization. Country specific unit cost was multiplied with resource used to get per person cost. The difference in costs per participant between intervention and TAU arms was 31873PKR (US$113). The Incremental Cost Effectiveness Ratio (ICER) was calculated based on between-arm differences in estimated cost and QALYs gains in the sampled population. The ICER for the intervention versus TAU was 243138PKR (US$859)/QALY gain. The intervention proved to be cost-effective with significantly lower ICER compared to threshold recommended by the WHO (i.e. 4515 = 3 x GDP Per Capita).
Conclusion: Results highlighted that the Moving on ABC plus intervention is cost-effective compared to TAU. These findings suggest that implementing culturally relevant and management intervention for comorbid mental health problems may lead to significant societal cost savings.
Methods: Eligible consented participants, recruited from participating hospitals and community centres in Pakistan, were assessed at baseline, 4 and 6- month post-randomization. Participants in the intervention arm received 12 sessions over 4 months. Client Service Receipt Inventory was used to record health service utilization and EQ-5D-3L to measure health related quality adjusted life years (QALYs).
Results: Participants (n=354) were randomized (1:1) into Moving on ABC Plus or Treatment as Usual (TAU) arm. Total QALY gained in the intervention arm was 0.47 compared to 0.34 in TAU arm at 4-month post-randomization. Country specific unit cost was multiplied with resource used to get per person cost. The difference in costs per participant between intervention and TAU arms was 31873PKR (US$113). The Incremental Cost Effectiveness Ratio (ICER) was calculated based on between-arm differences in estimated cost and QALYs gains in the sampled population. The ICER for the intervention versus TAU was 243138PKR (US$859)/QALY gain. The intervention proved to be cost-effective with significantly lower ICER compared to threshold recommended by the WHO (i.e. 4515 = 3 x GDP Per Capita).
Conclusion: Results highlighted that the Moving on ABC plus intervention is cost-effective compared to TAU. These findings suggest that implementing culturally relevant and management intervention for comorbid mental health problems may lead to significant societal cost savings.