Promoção de saúde e estilo de vida saudável: "Solid Facts" e abordagem nacional = Health and Healthy Lifestyle Promotion in Children and Adolescents: “Solid Facts” and National Approach
A educação pela aventura: desmistificando sensações e emoções
Currently, an increasing valuation of the tourism in the nature, and of the practical one of the ... more Currently, an increasing valuation of the tourism in the nature, and of the practical one of the Physical Activities of Adventure in Nature - AFAN is verified, for people to the search of better quality of life and for the fortalecimento of ambient ethics. Ahead of this, we search to analyze and to reflect on the sensations, emotions and educative possibilities of the AFAN of the practitioners of hiking of the ESFA (Superior School San Francisco de Assis). The research was characterized as qualitative and the used instrument of verification was the interview and the participant comment. The sample was composed for 10 practitioners of the group of hiking of the ESFA. The data had allowed to conclude them that the AFAN propitiate its practitioners the experience of sensations and emotions that assist in the formation of the integral and active citizen of the society, through the inserted educative possibilities in its context.
An Approach to Develop Software that Uses Blockchain
Advances in Intelligent Systems and Computing, 2018
Nowadays Blockchain technology has a great market visibility. The popularization of this concept ... more Nowadays Blockchain technology has a great market visibility. The popularization of this concept can be attributed to the exponential success of the Bitcoin cryptocurrency, launched in 2008 by Satoshi Nakamoto. The disruptive vision of this technology and the diverse possibilities of application in different businesses have been generating a series of changes and investments in the market, especially in the financial sector. The emergence of several Fintechs (Startups from the financial sector) that guide their software to Blockchain demonstrates the investments made to advance this technology. In this work, a bibliographical research was carried out in order to understand the state of the art of Blockchain and an experience of use was presented, where an application was developed using this technology, being source of information for the detailed definition of a software development process, based on Lean Startup, to support startups working with projects involving Blockchain.
Maize is an important source of phenolic compounds, specially hydroxycinnamic acids, which are wi... more Maize is an important source of phenolic compounds, specially hydroxycinnamic acids, which are widely known for their antioxidant activity and associated health benefits. However, these effects depend on their bioaccessibility, which is influenced by the different techniques used for food processing. Several traditional products can be obtained from maize and, in Portugal, it is used for the production of an ethnic bread called broa. In order to evaluate the effect of processing on maize phenolic composition, one commercial hybrid and five open-pollinated maize flours and broas were studied. The total phenolic content and antioxidant activity were evaluated by the Folin-Ciocalteu and ORAC assays, respectively. The major phenolics, namely ferulic and p-coumaric acids (in their soluble-free, soluble-conjugated and insoluble forms), insoluble ferulic acid dimers and soluble hydroxycinnamic acid amides were quantitated. Results show that the total phenolic content, antioxidant activity ...
Genetic atypical hemolytic uremic syndrome in children: a 20-year experience from a tertiary cent... more Genetic atypical hemolytic uremic syndrome in children: a 20-year experience from a tertiary center Síndrome hemolítica urêmica atípica genética em crianças: uma experiência de 20 anos a partir de um centro terciário
Enquadramento: a reforma envolve uma dimensão individual e social, constituindo um marco no desen... more Enquadramento: a reforma envolve uma dimensão individual e social, constituindo um marco no desenvolvimento do indivíduo. Planear esta transição torna-se fundamental para melhorar a satisfação e qualidade de vida. Objetivos: identificar os fatores facilitadores do processo de transição saudável para a reforma. Metodologia: a revisão integrativa envolveu a pesquisa nos motores de busca: CINAHL Complete; MEDLINE; Nursing & Allied Health Collection; Cochrane Central Register of Controlled Trials; Cochrane Methodology Register; Library, Information Science & Technology s e MedicLatina, tendo-se obtido inicialmente 231 produções científicas que, após a análise segundo os critérios de inclusão, foram elegidos 7 artigos. Resultados: os fatores determinantes para o sucesso desta transição são: idade, género, escolaridade, saúde, rede social, estilo de vida que antecede a reforma, satisfação com a vida ativa e condição financeira. A literacia em saúde e preparação para a reforma influencia e...
PW 2510 Burden and risk factors for drowning in portugal from 2008 to 2015
Abstracts, 2018
Drowning is an important, multisectoral, preventable and public health issue. This study aims to ... more Drowning is an important, multisectoral, preventable and public health issue. This study aims to examine the burden and risk factors for drowning in Portugal from 2008 to 2015. The information was collected based on two databases from the Directorate-General of Health, Public Health (ICD codes Accidental non-transport drowning and submersion W65-W74) and from the National Maritime Authority. The Public Health database allowed a national overview on drowning for accidental non-transport drowning and submersion, being the National Maritime Authority (ISN) data used for drowning on the beach. There was an average of 69 deaths/year in the period between 2008 and 2015 (ICD W65-W74). The number of deaths in unguarded beaches corresponds to 74% (n=73), with an average of 9.1 deaths per year. In guarded beaches, the average was 3.3 (data ISN). In the same time period, there was a 5% increase in the number of licensed lifeguards, with an average of 698 rescues per year. Concomitantly, a total of 697 communication actions were developed with the aim of preventing drownings.
The occurrence and fate of pharmaceuticals in the aquatic environment is recognized as one of the... more The occurrence and fate of pharmaceuticals in the aquatic environment is recognized as one of the emerging issues in environmental chemistry. Conventional wastewater treatment plants (WWTPs) are not designed to remove pharmaceuticals (and their metabolites) from domestic wastewaters. The treatability of pharmaceutical compounds in WWTPs varies considerably depending on the type of compound since their biodegradability can differ significantly. As a consequence, they may reach the aquatic environment, directly or by leaching of the sludge produced by these facilities. Currently, the technologies under research for the removal of pharmaceuticals, namely membrane technologies and advanced oxidation processes, have high operation costs related to energy and chemical consumption. When chemical reactions are involved, other aspects to consider include the formation of harmful reaction by-products and the management of the toxic sludge produced. Research is needed in order to develop econo...
Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2018
We report three simultaneous measles outbreaks with 112 confirmed cases in three Health Regions o... more We report three simultaneous measles outbreaks with 112 confirmed cases in three Health Regions of Portugal, from February to April 2018. The mean age of cases was 30 years, 79% worked in a healthcare setting and 87% were vaccinated. Genotype B3 was identified in 84 cases from the three outbreaks. Primary cases in each outbreak were imported. Several cases presented with modified measles, highlighting the importance of rethinking the measles case definition for vaccinated cases.
Environmental science and pollution research international, Jan 10, 2018
Removal of emerging pollutants, such as pharmaceuticals, from wastewater is a challenge. Adsorpti... more Removal of emerging pollutants, such as pharmaceuticals, from wastewater is a challenge. Adsorption is a simple and efficient process that can be applied. Clays, which are natural and low-cost materials, have been investigated as adsorbent. In this work, raw vermiculite and its three modified forms (expanded, base, and acid/base treated) were tested for removal of a widely used antidepressant, venlafaxine. Adsorption kinetics followed Elovich's model for raw vermiculite while the pseudo-2nd order model was a better fit in the case of other materials. Equilibrium followed Langmuir's model for the raw and the acid/base-treated vermiculite, while Redlich-Peterson's model fitted better the expanded and the base-treated materials. The adsorption capacity of vermiculite was significantly influenced by the changes in the physical and chemical properties of the materials caused by the treatments. The base-treated, raw, and expanded vermiculites showed lower maximum adsorption ca...
Clinical cancer research : an official journal of the American Association for Cancer Research, Jan 23, 2018
One-third of ER-positive breast cancer patients who initially respond to endocrine therapy become... more One-third of ER-positive breast cancer patients who initially respond to endocrine therapy become resistant to treatment. Such treatment failure is associated with poor prognosis and remains an area of unmet clinical need. Here we identify a specific post-translational modification that occurs during endocrine resistance and which results in tumour susceptibility to the apoptosis inducer TNF-Related Apoptosis-Inducing Ligand (TRAIL). This potentially offers a novel stratified approach to targeting endocrine resistant breast cancer. Cell line and primary-derived xenograft models of endocrine resistance were investigated for susceptibility to TRAIL. Tumour viability, cancer stem cell (CSC) viability (tumourspheres), tumour growth kinetics and metastatic burden were assessed. Western blots for the TRAIL-pathway inhibitor, c-FLIP, and upstream regulators were performed. Results were confirmed in primary culture of 26 endocrine-resistant and endocrine-naïve breast tumours. Breast can...
Journal of Environmental Science and Engineering A, 2017
The dynamics of forest growth are related to the succession stage, the quality of the environment... more The dynamics of forest growth are related to the succession stage, the quality of the environment and the degree of anthropism. The growth of a forest is given by the activity of live trees, mortality, and trees that are cut or recruited during the growing period. A way of representing the growth dynamics of a forest is by the Transition Matrix, with the divisibility of the population in states, with probabilities of movement from one state to another, over time. Forest dynamics studies are carried out by means of a continuous forest inventory, allowing the calculation of gains and losses in basal area, mortality rates and ingrowth. In this study, the measurements were performed with a 5-year interval, on 27 plots distributed in 12 sites. The methodology correlated parameters of the forest dynamics with canopy, soil, relief and hydrographic parameters. An indicator of forest growth dynamics was proposed and it was tested. It was confirmed that the density factor interferes in growth dynamics of the forest.
A multicriteria model to support the definition of a software testing methodology for micro and small enterprises
2016 11th Iberian Conference on Information Systems and Technologies (CISTI), 2016
Many of the micro and small-sized companies still do not have a formal testing process and do not... more Many of the micro and small-sized companies still do not have a formal testing process and do not even have the ability to implement a process that meets the needs and ensures the correct execution of activities. In addition, these companies have unique characteristics, in general, they develop smaller and less complex software, avoid expensive tools and complex procedures, because they do not have many financial resources. This paper presents the definition of a testing methodology possibly more viable for the reality of micro and small-sized companies. The testing methodology is based on the IEEE 829 Standard and was defined with the assistance of software testing experts, along with professionals working in micro and smalls-sized companies through an approach structured in multicriteria.
A Process for Creating the Elicitation Guide of Non-functional Requirements
Advances in Intelligent Systems and Computing, 2016
Non-functional requirements play a crucial role in the process of software development because th... more Non-functional requirements play a crucial role in the process of software development because they correspond to the characteristics and restrictions on which the software must running. The earlier this information is available, the faster the decision process of the solution that will best meet the customer need. However, the elicitation of these requirements is not an easy task. This paper presents a process that aims at the construction of a guide that assists analysts in identifying the requirements for the customer software context. The first run of the process showed that the results are motivators.
Promoção de saúde e estilo de vida saudável: "Solid Facts" e abordagem nacional = Health and Healthy Lifestyle Promotion in Children and Adolescents: “Solid Facts” and National Approach
A educação pela aventura: desmistificando sensações e emoções
Currently, an increasing valuation of the tourism in the nature, and of the practical one of the ... more Currently, an increasing valuation of the tourism in the nature, and of the practical one of the Physical Activities of Adventure in Nature - AFAN is verified, for people to the search of better quality of life and for the fortalecimento of ambient ethics. Ahead of this, we search to analyze and to reflect on the sensations, emotions and educative possibilities of the AFAN of the practitioners of hiking of the ESFA (Superior School San Francisco de Assis). The research was characterized as qualitative and the used instrument of verification was the interview and the participant comment. The sample was composed for 10 practitioners of the group of hiking of the ESFA. The data had allowed to conclude them that the AFAN propitiate its practitioners the experience of sensations and emotions that assist in the formation of the integral and active citizen of the society, through the inserted educative possibilities in its context.
An Approach to Develop Software that Uses Blockchain
Advances in Intelligent Systems and Computing, 2018
Nowadays Blockchain technology has a great market visibility. The popularization of this concept ... more Nowadays Blockchain technology has a great market visibility. The popularization of this concept can be attributed to the exponential success of the Bitcoin cryptocurrency, launched in 2008 by Satoshi Nakamoto. The disruptive vision of this technology and the diverse possibilities of application in different businesses have been generating a series of changes and investments in the market, especially in the financial sector. The emergence of several Fintechs (Startups from the financial sector) that guide their software to Blockchain demonstrates the investments made to advance this technology. In this work, a bibliographical research was carried out in order to understand the state of the art of Blockchain and an experience of use was presented, where an application was developed using this technology, being source of information for the detailed definition of a software development process, based on Lean Startup, to support startups working with projects involving Blockchain.
Maize is an important source of phenolic compounds, specially hydroxycinnamic acids, which are wi... more Maize is an important source of phenolic compounds, specially hydroxycinnamic acids, which are widely known for their antioxidant activity and associated health benefits. However, these effects depend on their bioaccessibility, which is influenced by the different techniques used for food processing. Several traditional products can be obtained from maize and, in Portugal, it is used for the production of an ethnic bread called broa. In order to evaluate the effect of processing on maize phenolic composition, one commercial hybrid and five open-pollinated maize flours and broas were studied. The total phenolic content and antioxidant activity were evaluated by the Folin-Ciocalteu and ORAC assays, respectively. The major phenolics, namely ferulic and p-coumaric acids (in their soluble-free, soluble-conjugated and insoluble forms), insoluble ferulic acid dimers and soluble hydroxycinnamic acid amides were quantitated. Results show that the total phenolic content, antioxidant activity ...
Genetic atypical hemolytic uremic syndrome in children: a 20-year experience from a tertiary cent... more Genetic atypical hemolytic uremic syndrome in children: a 20-year experience from a tertiary center Síndrome hemolítica urêmica atípica genética em crianças: uma experiência de 20 anos a partir de um centro terciário
Enquadramento: a reforma envolve uma dimensão individual e social, constituindo um marco no desen... more Enquadramento: a reforma envolve uma dimensão individual e social, constituindo um marco no desenvolvimento do indivíduo. Planear esta transição torna-se fundamental para melhorar a satisfação e qualidade de vida. Objetivos: identificar os fatores facilitadores do processo de transição saudável para a reforma. Metodologia: a revisão integrativa envolveu a pesquisa nos motores de busca: CINAHL Complete; MEDLINE; Nursing & Allied Health Collection; Cochrane Central Register of Controlled Trials; Cochrane Methodology Register; Library, Information Science & Technology s e MedicLatina, tendo-se obtido inicialmente 231 produções científicas que, após a análise segundo os critérios de inclusão, foram elegidos 7 artigos. Resultados: os fatores determinantes para o sucesso desta transição são: idade, género, escolaridade, saúde, rede social, estilo de vida que antecede a reforma, satisfação com a vida ativa e condição financeira. A literacia em saúde e preparação para a reforma influencia e...
PW 2510 Burden and risk factors for drowning in portugal from 2008 to 2015
Abstracts, 2018
Drowning is an important, multisectoral, preventable and public health issue. This study aims to ... more Drowning is an important, multisectoral, preventable and public health issue. This study aims to examine the burden and risk factors for drowning in Portugal from 2008 to 2015. The information was collected based on two databases from the Directorate-General of Health, Public Health (ICD codes Accidental non-transport drowning and submersion W65-W74) and from the National Maritime Authority. The Public Health database allowed a national overview on drowning for accidental non-transport drowning and submersion, being the National Maritime Authority (ISN) data used for drowning on the beach. There was an average of 69 deaths/year in the period between 2008 and 2015 (ICD W65-W74). The number of deaths in unguarded beaches corresponds to 74% (n=73), with an average of 9.1 deaths per year. In guarded beaches, the average was 3.3 (data ISN). In the same time period, there was a 5% increase in the number of licensed lifeguards, with an average of 698 rescues per year. Concomitantly, a total of 697 communication actions were developed with the aim of preventing drownings.
The occurrence and fate of pharmaceuticals in the aquatic environment is recognized as one of the... more The occurrence and fate of pharmaceuticals in the aquatic environment is recognized as one of the emerging issues in environmental chemistry. Conventional wastewater treatment plants (WWTPs) are not designed to remove pharmaceuticals (and their metabolites) from domestic wastewaters. The treatability of pharmaceutical compounds in WWTPs varies considerably depending on the type of compound since their biodegradability can differ significantly. As a consequence, they may reach the aquatic environment, directly or by leaching of the sludge produced by these facilities. Currently, the technologies under research for the removal of pharmaceuticals, namely membrane technologies and advanced oxidation processes, have high operation costs related to energy and chemical consumption. When chemical reactions are involved, other aspects to consider include the formation of harmful reaction by-products and the management of the toxic sludge produced. Research is needed in order to develop econo...
Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2018
We report three simultaneous measles outbreaks with 112 confirmed cases in three Health Regions o... more We report three simultaneous measles outbreaks with 112 confirmed cases in three Health Regions of Portugal, from February to April 2018. The mean age of cases was 30 years, 79% worked in a healthcare setting and 87% were vaccinated. Genotype B3 was identified in 84 cases from the three outbreaks. Primary cases in each outbreak were imported. Several cases presented with modified measles, highlighting the importance of rethinking the measles case definition for vaccinated cases.
Environmental science and pollution research international, Jan 10, 2018
Removal of emerging pollutants, such as pharmaceuticals, from wastewater is a challenge. Adsorpti... more Removal of emerging pollutants, such as pharmaceuticals, from wastewater is a challenge. Adsorption is a simple and efficient process that can be applied. Clays, which are natural and low-cost materials, have been investigated as adsorbent. In this work, raw vermiculite and its three modified forms (expanded, base, and acid/base treated) were tested for removal of a widely used antidepressant, venlafaxine. Adsorption kinetics followed Elovich's model for raw vermiculite while the pseudo-2nd order model was a better fit in the case of other materials. Equilibrium followed Langmuir's model for the raw and the acid/base-treated vermiculite, while Redlich-Peterson's model fitted better the expanded and the base-treated materials. The adsorption capacity of vermiculite was significantly influenced by the changes in the physical and chemical properties of the materials caused by the treatments. The base-treated, raw, and expanded vermiculites showed lower maximum adsorption ca...
Clinical cancer research : an official journal of the American Association for Cancer Research, Jan 23, 2018
One-third of ER-positive breast cancer patients who initially respond to endocrine therapy become... more One-third of ER-positive breast cancer patients who initially respond to endocrine therapy become resistant to treatment. Such treatment failure is associated with poor prognosis and remains an area of unmet clinical need. Here we identify a specific post-translational modification that occurs during endocrine resistance and which results in tumour susceptibility to the apoptosis inducer TNF-Related Apoptosis-Inducing Ligand (TRAIL). This potentially offers a novel stratified approach to targeting endocrine resistant breast cancer. Cell line and primary-derived xenograft models of endocrine resistance were investigated for susceptibility to TRAIL. Tumour viability, cancer stem cell (CSC) viability (tumourspheres), tumour growth kinetics and metastatic burden were assessed. Western blots for the TRAIL-pathway inhibitor, c-FLIP, and upstream regulators were performed. Results were confirmed in primary culture of 26 endocrine-resistant and endocrine-naïve breast tumours. Breast can...
Journal of Environmental Science and Engineering A, 2017
The dynamics of forest growth are related to the succession stage, the quality of the environment... more The dynamics of forest growth are related to the succession stage, the quality of the environment and the degree of anthropism. The growth of a forest is given by the activity of live trees, mortality, and trees that are cut or recruited during the growing period. A way of representing the growth dynamics of a forest is by the Transition Matrix, with the divisibility of the population in states, with probabilities of movement from one state to another, over time. Forest dynamics studies are carried out by means of a continuous forest inventory, allowing the calculation of gains and losses in basal area, mortality rates and ingrowth. In this study, the measurements were performed with a 5-year interval, on 27 plots distributed in 12 sites. The methodology correlated parameters of the forest dynamics with canopy, soil, relief and hydrographic parameters. An indicator of forest growth dynamics was proposed and it was tested. It was confirmed that the density factor interferes in growth dynamics of the forest.
A multicriteria model to support the definition of a software testing methodology for micro and small enterprises
2016 11th Iberian Conference on Information Systems and Technologies (CISTI), 2016
Many of the micro and small-sized companies still do not have a formal testing process and do not... more Many of the micro and small-sized companies still do not have a formal testing process and do not even have the ability to implement a process that meets the needs and ensures the correct execution of activities. In addition, these companies have unique characteristics, in general, they develop smaller and less complex software, avoid expensive tools and complex procedures, because they do not have many financial resources. This paper presents the definition of a testing methodology possibly more viable for the reality of micro and small-sized companies. The testing methodology is based on the IEEE 829 Standard and was defined with the assistance of software testing experts, along with professionals working in micro and smalls-sized companies through an approach structured in multicriteria.
A Process for Creating the Elicitation Guide of Non-functional Requirements
Advances in Intelligent Systems and Computing, 2016
Non-functional requirements play a crucial role in the process of software development because th... more Non-functional requirements play a crucial role in the process of software development because they correspond to the characteristics and restrictions on which the software must running. The earlier this information is available, the faster the decision process of the solution that will best meet the customer need. However, the elicitation of these requirements is not an easy task. This paper presents a process that aims at the construction of a guide that assists analysts in identifying the requirements for the customer software context. The first run of the process showed that the results are motivators.
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Papers by Andreia Silva