Papers by Alberto Di Blasio
Minerva dental and oral science, Jun 1, 2018
BACKGROUND Moebius syndrome is a rare condition characterized by bilateral facial and abducens ne... more BACKGROUND Moebius syndrome is a rare condition characterized by bilateral facial and abducens nerve paralysis. The aim of this study is to evaluate the main orthodontic features and the frequency of associated clinical characteristics in patients with Moebius syndrome (MS). METHODS According to Terzis classifications, 58 patients with MS aged 8 months to 46 years old underwent orthodontics and clinical examination. RESULTS Strabismus, upper and lower limb malformations, lip and palatal cleft were frequently associated with MS. Reduced TM movements were noted (48%). Cephalometric analysis did not allow identifying a typical facies and a characteristic cephalometric pattern; we have noticed a higher prevalence of Class II (56%) with micrognathia and excessive maxillary development probably due to the lack of lip seal. Early treatment is recommended, with a multidisciplinary approach to reduce the impact of sequelae on the lives of MS patients or their families. CONCLUSIONS Early treatment is recommended, with a multidisciplinary approach to diminish the impact of sequelae on the lives of MS patients or their families.
PubMed, Mar 1, 1990
Current orthodontic treatment aims not only at achieving a good, stable functional occlusion but,... more Current orthodontic treatment aims not only at achieving a good, stable functional occlusion but, increasingly, at improving the cosmetical appearance of the face and profile. To this end, the Authors believe that proper analysis of the nasolabial angle is an important consideration. A cephalometric evaluation of the soft tissue nasolabial angle and its relationship to craniofacial bony landmarks is described. Statistical data are presented from a preliminary sample of 32 orthodontic patients of whom 15 were habitual oronasal breathers. The absolute value of the nasolabial angle was very similar in the two groups but the orientation of the nasolabial angle relative to cephalometric landmarks showed statistically significant differences.
Oral Radiology, Mar 21, 2017
significant difference was found between the two methods for measuring averaged soft tissue thick... more significant difference was found between the two methods for measuring averaged soft tissue thickness, but a 20% difference was found for the single measurements. High correlation and concordance between the ultrasonographic and radiographic measurements, but no significant difference, was found between the single and averaged ANB angle measurements. Conclusion Ultrasonography seems to be a noninvasive and reliable technique for measurement of the ANB angle and may replace radiographic measurement in some cases.
PubMed, May 6, 2016
Aim: The aim of the present study was to investigate the efficacy of environmental scanning elect... more Aim: The aim of the present study was to investigate the efficacy of environmental scanning electron microscopy (ESEM), in low vacuum mode (LV-ESEM) and in wet mode (wet-ESEM) in the assessment of cell-material interactions. Methods: Mouse calvaria MC3T3 cells (ATCC) were seeded on commercially pure machined titanium discs of 10 mm diameter in Dulbecco modified MEM, 10% Fetal Bovine Serum, 1% Penicillin and Streptomycin and 1% Glutamine. Samples were then processed for microscope observation by rinse in Phosphate Buffer saline and fixation in 4.5% Glutaraldehyde. Samples were then rinsed in Sodium Cacodylate buffer and observed or dehydrated in alcohol prior to LV-ESEM observation. Fresh samples in 0.9% NaCl solution were observed in wet- ESEM. Results: No significant loss of detail was observed when dehydrated or non dehydrated samples were analysed at LV-ESEM.The observation of fresh samples in wet-ESEM however proved difficult for the need to eliminate water which forms a layer covering the sample, thus hiding cell surface details. When reducing the vapor pressure in the chamber, the layer evaporated and NaCl immediately started to precipitate and cells collapsed, thus no further investigation was possible. Conclusions: The use of low vacuum-ESEM after cell fixation, but without dehydration or gold sputter coating proved a viable alternative to traditional high vacuum SEM observation.
Journal of Craniofacial Surgery, Nov 1, 2017
No agreement exists on the most appropriate timing of orthodontic treatment in patients with clef... more No agreement exists on the most appropriate timing of orthodontic treatment in patients with cleft lip and palate. The aim of this study is to investigate the effect of early orthodontic treatment on development of the dental arches and alveolar bone. A dental casts analysis was performed on 28 children with cleft lip and palate before orthodontic treatment (T0; mean age, 6.5 AE 1.7) and at the end of active treatment (T1; mean age, 9.2 AE 2.1 years). The considered variables were: intercanine and intermolar distances; dental arch relationships, evaluated according to the modified Huddart/Bodenham system. The study group was divided into 2 samples according to the age at T0: Group A (age < 6 years) and Group B (age ! 6 years). A statistical comparison of the treatment effects between the 2 samples was performed. Patients in Group A exhibited a greater increase of intercanine distance (8 mm versus 2.7 mm; P<0.001), intermolar distance (7.2 mm versus 5 mm; P ¼ 0.06), and Huddart/Bodenham score (7.1 versus 3; P < 0.05) when compared with patients in Group B. Early orthodontic treatment strongly improved the dental arch relationship, since subjects starting the therapy before the age of 6 had a better response in terms of anterior maxillary expansion.
Journal of Cranio-maxillofacial Surgery, 2019
PURPOSE To quantify the surface facial asymmetry in a group of young patients with hemifacial mic... more PURPOSE To quantify the surface facial asymmetry in a group of young patients with hemifacial microsomia (HFM) and to investigate differences with a homogeneous sample of healthy subjects, using a novel stereophotogrammetric method. MATERIALS AND METHODS Twelve patients (mean age 13.1 ± 3.1 years) with different degrees of HFM and 15 healthy controls (mean age 12.2 ± 3.5 years) were imaged with a stereophotogrammetric facial scanner. The root mean square error (RMSE) of the distances between the corresponding points of each original photograph and its mirror copy was calculated for the whole face and for each trigeminal third, as defined by the innervation of trigeminal branches. A statistical analysis was performed to compare the RMSE value of all facial areas within each group and between patients and controls. RESULTS RMSE values progressively increased from the upper to the lower third of face, both in patients and controls. The level of asymmetry was significantly higher in HFM subjects for middle third (p < 0.01), lower third (p < 0.001) and whole face (p < 0.001); no statistically significant differences were found between the groups for the upper third. CONCLUSIONS The reported technique provides an accurate topographic analysis of the facial asymmetry, and is recommended for conditions such as HFM affecting only part of the face.
International Journal of Environmental Research and Public Health, May 13, 2021
This article is an open access article distributed under the terms and conditions of the Creative... more This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY
Case Reports in Dentistry, 2017
Case Reports in Dentistry, 2017
e aim of this paper is to report treatment e ects of functional therapy in a growing patient a ec... more e aim of this paper is to report treatment e ects of functional therapy in a growing patient a ected by hemifacial microsomia (HM). According to Kaban's classi cation, the patient was classi ed as grade IIa as she presented all mandibular and temporomandibular joint components and a normal shaped, hypoplastic mandible. e therapeutic approach included the use of an asymmetrical functional activator (AFA) to stimulate the growth of the a ected side and consequently to improve symmetry of the mandible and maxillary de ciency. Further e ects were the lengthening of the mandibular ramus, restoration of occlusion, and expansion of soft tissues.
Case Reports in Dentistry, 2017
The authors report a combined orthodontic-surgical correction of an adult patient's malocclusion ... more The authors report a combined orthodontic-surgical correction of an adult patient's malocclusion affected by Moebius Syndrome (MS). The treatment was conducted at the Dentistry Unit and the Maxillofacial Surgery Unit of the University Hospital of Parma. Treatment of malocclusion was performed after the correction of facial mimic mobility with smile surgery. The postoperative stability and orthodontic results were good and the correction of the morphological problems related to the syndrome was very satisfactory.
Applied sciences, Nov 25, 2022
This article is an open access article distributed under the terms and conditions of the Creative... more This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY
International Journal of Environmental Research and Public Health, Apr 17, 2021
This article is an open access article distributed under the terms and conditions of the Creative... more This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY
European Journal of Oral Sciences, Mar 30, 2021
The aim of this study was to evaluate the masticatory pattern in children with cleft lip and/or p... more The aim of this study was to evaluate the masticatory pattern in children with cleft lip and/or palate (CL/P) through investigation of the prevalence of reverse sequencing chewing cycles. The study group included 18 patients with CL/P (mean age: 7.4 yr, SD: 1.4 yr), 15 of whom had dental crossbite. The controls included a group of 18 non‐CL/P children with the same types of crossbite as the study group (mean age: 7.2 yr, SD: 1.5 yr) and a group of 18 non‐CL/P subjects with normal occlusion (mean age: 9.8 yr, SD: 1.9 yr). Mandibular movements during chewing of soft and hard bolus were recorded with a kinesiograph. Kinematic signals were analysed using a custom‐made software. A statistical analysis was performed to compare the degree of reverse‐sequencing chewing cycles between patients and controls (Kruskal–Wallis test with Dwass‐Steel‐Critchlow‐Fligner pairwise comparisons post hoc test). A significant difference between patients with CL/P and non‐CL/P subjects with normal occlusion was highlighted on the left side of mastication, which was the side with the higher prevalence of crossbite with both types of bolus. No statistical differences were found between CL/P patients and healthy controls with crossbite. Cleft‐affected patients with posterior crossbite exhibited an anomalous masticatory pattern with increased reverse chewing cycles on the crossbite side.
Journal of Craniofacial Surgery, May 1, 2015
The early high condylectomy (HC), removing the overgrowing area of the condyle, may be indicated ... more The early high condylectomy (HC), removing the overgrowing area of the condyle, may be indicated for condylar hyperplasia. However, in young patients, when the HC removes the pathological overgrowing tissue the contralateral condyle is still growing. May this surgical procedure, in these growing patients, stop the operated side growth creating the conditions for an opposite asymmetry? Authors investigate the way the operated mandible develops after the early HC, both as a symmetry percentage and in an absolute value related to the unaffected side. A sample of 8 consecutive growing patients, 1 male and 7 females, referred to the Maxillofacial Surgery Department of Parma University for HC were investigated. Patients were longitudinally studied with 3 orthopantomographies at: T0 (diagnosis: mean age, 13 years; range, 11 years 2 months to 13 years 8 months), T1 (after surgery: mean age, 15; range, 13-18 years) and T2 (follow-up: mean age, 18 years; range, 17-20 years). The x-ray is used to study the condyle, ramus, and total vertical structures length by Mattila tracing method. The data were analyzed by the Student t test and Wilcoxon matched pairs test; P value was set at 0.5. The operated side was overcorrected by HC and; during the investigated period, its growth decreased from T0 to T1 and restarted from T1 to T2. The whole T0-T2 growth of the operated side was not statistically different from the one of the healthy side (P < 0.05). These results suggest that the operated side growth may continue in a more normal way after condylectomy.
British Journal of Oral and Maxillofacial Surgery, 2016
Both the correct position of the patient's head and a standard system for the acquisition of imag... more Both the correct position of the patient's head and a standard system for the acquisition of images are essential for objective evaluation of the facial profile and the skull, and for longitudinal superimposition. The natural position of the head was introduced into orthodontics in the late 1950s, and is used as a postural basis for craniocervical and craniofacial morphological analysis. It can also have a role in the planning of the surgical correction of craniomaxillofacial deformities. The relatively recent transition in orthodontics from 2-dimensional to 3-dimensional imaging, and from analogue to digital technology, has renewed attention in finding a versatile method for the establishment of an accurate and reliable head position during the acquisition of serial records. In this review we discuss definition, clinical applications, and procedures to establish the natural head position and their reproducibility. We also consider methods to reproduce and record the position in two and three planes.
Dental Materials, 2014
d e n t a l m a t e r i a l s 3 0 S (2 0 1 4) e1-e180 e89 restorations. The use of low modulus li... more d e n t a l m a t e r i a l s 3 0 S (2 0 1 4) e1-e180 e89 restorations. The use of low modulus lining materials significantly increased the creep strain of the whole restorations and may disrupt the interfacial sealing at the cavity floor.
The Angle Orthodontist, 2009
This case report shows the possibility of the application of a mandibular osteotomy to resolve ma... more This case report shows the possibility of the application of a mandibular osteotomy to resolve mandibular asymmetry with independent and discordant movements of both bony segments. The authors report the case of a 25-year-old woman referred for mandibular asymmetry, with a transverse excess of the right hemi mandible and vertical defect of the left one. The patient underwent a bilateral sagittal split osteotomy, midline osteotomy, and genioplasty, which corrected the mandibular asymmetry with contraction of the entire right hemi mandible. A slight left vertical increase was also obtained through the surgically created lateral open bite. In the follow-up assessment, the patient's face appeared symmetrical with normalization of the bizygomatic-bigonial relationships, and the facial shape corresponded to ideal anthropometric features. This technique resulted in resolution of mandibular asymmetry. In addition, mandibular osteotomy permits the esthetic management of the shape of the ...
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Papers by Alberto Di Blasio