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Alan Moore

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Trinity College Dublin

Trinity College Dublin

University of the Basque Country/ Euskal Herriko Unibertsitatea (EHU/UPV) and IKERBASQUE, Basque Foundation for Science,

Moscow State University

Nikolai Gaponik

Andrey Chuvilin

Concordia University (Canada)

Giancarlo Righini

Consiglio Nazionale delle Ricerche (CNR)

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Papers by Alan Moore

Spontaneous emission enhancement in a microtube cavity with highly confined optical modes

SPIE Proceedings, 2007

A detailed study of the photonic modes in microtube cavity of ~ 7-8 µm outer diameter is presente... more A detailed study of the photonic modes in microtube cavity of ~ 7-8 µm outer diameter is presented. We demonstrate a new route to the fabrication of individual microtubes with the maximum length of 200 µm, using a vacuum assisted wetting and filtration through a microchannel glass matrix. The microtubes were studied using micro-photoluminescence spectroscopy and luminescence lifetime imaging confocal microscopy. In the emission spectra of the microresonators we find periodic very narrow peaks corresponding to the whispering gallery modes of two orthogonal polarizations with quality factors upto 3200 at room temperature. In order to identify the peaks in the observed mode structure, we have adopted the boundary-value solution to the problem of scattering of electromagnetic waves by a dielectric microcylinder. A strong enhancement in photoluminescence decay rates at high excitation power suggest the occurrence of amplified spontaneous emission from a single microtube. The evanescent field in these photonic structures extends a couple of micrometers into the surroundings providing the possibility for efficient coupling to an external photonic device.

Rutile exsolution in orthopyroxene

Contributions to Mineralogy and Petrology, 1968

Rutile has been identified as an exsolution product in orthopyroxenes from Gosse Pile, Giles Comp... more

260 Comparison of Efficacy of Lumiracoxib with Celecoxib and Placebo in Knee Osteoarthritis Patients and Differing Baseline Disease Severity

Osteoarthritis and Cartilage, 2007

The aforementioned clinical outcomes and comparative analysis is essential for furthering our und... more

Influence of Stocking Densities on Walleye Fry Viability in Experimental and Production Tanks

The Progressive Fish-Culturist, 1994

In 1992 at Rathbun State Fish Hatchery, experiments were conducted to evaluate the effects of sto... more In 1992 at Rathbun State Fish Hatchery, experiments were conducted to evaluate the effects of stocking density on performance of larval walleyes (Stizostedion vitreum) in small (278-L) cylindrical tanks, and to compare fry performance in production-scale (6 79-L) and small tanks. Hatched fry were reared for 21 d and fed Fry Feed Kyowa B400 and B700 in all experiments. I>ensilies of 20, 30, and 40 fry/L were evaluated in two trials, and densities of 20, 50, and 60 fry/L were evaluated in another trial. Fry performance did not differ significantly among density treatments of 20, 30, or 40 fry/L. In the other trial, however, survival was significantly greater for fish stocked at 20 fry/L than for fish stocked at 50 or 60 fry/L, but the number of fry produced (yield) was 216% greater in the tanks stocked at 60 fry/L. Growth rate was not affected by density in any trial. For comparisons between 278-L and 679-L tanks, three 679-L tanks were stocked at 20 fry/L in each of the three trials. Survival and viability differences between tank sizes were inconsistent, but the highest survival was an average of 74.9% to 21 d posthatch in the three 679-L tanks in the second trial. Cannibalism and gas bladder inflation were more common in the small tanks. Incidence of cannibals was as high as 7.5% of the original number stocked in the small tanks, but did not exceed 3.5% in the large tanks. Over all three trials, from 98.5 to 100% of the survivors in the 278-L tanks, and from 88 to 96.3% in the 679-L tanks, had inflated gas bladders. The outstanding rate of gas bladder inflation is attributed to the use of a surface spray, which seems to clear the water surface of oil and debris. These experiments demonstrate the feasibility of mass culture of larval walleyes in production-scale tanks.

Efficacy of Lumiracoxib in Osteoarthritis: A Review of Nine Studies

Journal of International Medical Research, 2005

Lumiracoxib is a cyclooxygenase-2 selective inhibitor in development for the treatment of osteoar... more Lumiracoxib is a cyclooxygenase-2 selective inhibitor in development for the treatment of osteoarthritis (OA), rheumatoid arthritis and acute pain. We reviewed nine clinical studies of 1 − 52 weeks' duration demonstrating the efficacy of lumiracoxib in OA. Male and female patients aged ≥ 18 years with primary OA of the hand, hip or knee received lumiracoxib, placebo or active comparators (diclofenac, celecoxib or rofecoxib). Lumiracoxib provided consistent reductions in OA pain intensity and improvements in the patient's global assessment of disease activity and functional status (assessed using the Western Ontario and McMaster Universities Osteoarthritis Index questionnaire or the Australian/Canadian OA Hand Index). These results were superior to placebo and similar to the active comparators tested. In addition, lumiracoxib was consistently superior to placebo and generally similar to active comparators in terms of the new Outcome Measures in Clinical Trials and Osteoarthri...

Pharmacological options in the management of orthostatic hypotension in older adults

Expert Review of Cardiovascular Therapy, 2009

Orthostatic hypotension (OH) is a common disorder in older adults with potentially serious clinic... more Orthostatic hypotension (OH) is a common disorder in older adults with potentially serious clinical consequences. Understanding the key underlying pathophysiological processes that predispose individuals to OH is essential when making treatment decisions for this group of patients. In this article, we discuss the key antihypotensive agents used in the management of OH in older adults. Commonly, midodrine is used as a first-line agent, given its supportive data in randomized, controlled trials. Fludrocortisone has been evaluated in open-label trials and has long-established usage in clinical practice. Other agents are available and in clinical use, either alone or in combination, but larger randomized trial evaluations are yet to be published. It is important to bear in mind that a patient may be taking medications that predispose to or exacerbate the symptoms of OH. Withdrawal of such medications, where possible, should be considered before commencing other pharmacological agents that attenuate the symptoms of OH.

High power continuous operation of laser diodes at 1064 nm

Electronics Letters, 1991

selfcalibrating) rate. The spectral noise current of M1 and of the switches at its drain is reduc... more selfcalibrating) rate. The spectral noise current of M1 and of the switches at its drain is reduced by the gain Acf) at frequency 1: As the corner frequency of Acf) is usually much higher than the llfnoise corner frequency of M1, the remaining high-frequency noise of M1 is mainly determined by thermal noise, if the current density is sufficiently low. The noise current of the basic current source Q1 can be expected to be considerably less than that of an MOS current source because surface effects are reduced even if Q1 is a lateral tran~istor.~ Attention should be paid to the noise of the circuit generating the base voltage which could be the limiting factor to accuracy. High output resistance rmt in the hold mode can be achieved even if M1 is operating in saturation. With g , and go being the transconductance and the output conductance of M1, respectively, it can approximately be expressed as

The FRIENDS Program for Young Former-Yugoslavian Refugees in Australia: A Pilot Study

Behaviour Change, 2000

Young immigrants frequently experience anxiety as a consequence of the stress associated with mig... more Young immigrants frequently experience anxiety as a consequence of the stress associated with migration. Despite being at high risk for the development of psychopathology, culturally sensitive assessment and intervention procedures for use with ethnic minority groups residing in Australia have yet to be developed and validated. The aims of the current study were to (a) investigate the level of anxiety in a sample of former-Yugoslavian teenage refugees; (b) appraise the efficacy of the FRIENDS program, a validated Anglo-Australian anxiety-prevention program, for use with this high-risk group; and (c) obtain information from both the program participants and facilitators regarding how the intervention could be modified to better meet the needs of this growing refugee population in Australia. Twenty female former-Yugoslavian youths completed standardised measures of internalising symptoms. Participants were allocated to either an intervention (n = 9) or a waiting list (n = 11) conditio...

Evaluation of Tank Shape and a Surface Spray for Intensive Culture of Larval Walleyes Fed Formulated Feed

The Progressive Fish-Culturist, 1994

... Evaluation of Tank Shape and a Surface Spray for Intensive Culture of Larval Walleyes Fed For... more

Spontaneous emission enhancement in a microtube cavity with highly confined optical modes

SPIE Proceedings, 2007

A detailed study of the photonic modes in microtube cavity of ~ 7-8 µm outer diameter is presente... more A detailed study of the photonic modes in microtube cavity of ~ 7-8 µm outer diameter is presented. We demonstrate a new route to the fabrication of individual microtubes with the maximum length of 200 µm, using a vacuum assisted wetting and filtration through a microchannel glass matrix. The microtubes were studied using micro-photoluminescence spectroscopy and luminescence lifetime imaging confocal microscopy. In the emission spectra of the microresonators we find periodic very narrow peaks corresponding to the whispering gallery modes of two orthogonal polarizations with quality factors upto 3200 at room temperature. In order to identify the peaks in the observed mode structure, we have adopted the boundary-value solution to the problem of scattering of electromagnetic waves by a dielectric microcylinder. A strong enhancement in photoluminescence decay rates at high excitation power suggest the occurrence of amplified spontaneous emission from a single microtube. The evanescent field in these photonic structures extends a couple of micrometers into the surroundings providing the possibility for efficient coupling to an external photonic device.

Rutile exsolution in orthopyroxene

Contributions to Mineralogy and Petrology, 1968

Rutile has been identified as an exsolution product in orthopyroxenes from Gosse Pile, Giles Comp... more

260 Comparison of Efficacy of Lumiracoxib with Celecoxib and Placebo in Knee Osteoarthritis Patients and Differing Baseline Disease Severity

Osteoarthritis and Cartilage, 2007

The aforementioned clinical outcomes and comparative analysis is essential for furthering our und... more

Influence of Stocking Densities on Walleye Fry Viability in Experimental and Production Tanks

The Progressive Fish-Culturist, 1994

In 1992 at Rathbun State Fish Hatchery, experiments were conducted to evaluate the effects of sto... more In 1992 at Rathbun State Fish Hatchery, experiments were conducted to evaluate the effects of stocking density on performance of larval walleyes (Stizostedion vitreum) in small (278-L) cylindrical tanks, and to compare fry performance in production-scale (6 79-L) and small tanks. Hatched fry were reared for 21 d and fed Fry Feed Kyowa B400 and B700 in all experiments. I>ensilies of 20, 30, and 40 fry/L were evaluated in two trials, and densities of 20, 50, and 60 fry/L were evaluated in another trial. Fry performance did not differ significantly among density treatments of 20, 30, or 40 fry/L. In the other trial, however, survival was significantly greater for fish stocked at 20 fry/L than for fish stocked at 50 or 60 fry/L, but the number of fry produced (yield) was 216% greater in the tanks stocked at 60 fry/L. Growth rate was not affected by density in any trial. For comparisons between 278-L and 679-L tanks, three 679-L tanks were stocked at 20 fry/L in each of the three trials. Survival and viability differences between tank sizes were inconsistent, but the highest survival was an average of 74.9% to 21 d posthatch in the three 679-L tanks in the second trial. Cannibalism and gas bladder inflation were more common in the small tanks. Incidence of cannibals was as high as 7.5% of the original number stocked in the small tanks, but did not exceed 3.5% in the large tanks. Over all three trials, from 98.5 to 100% of the survivors in the 278-L tanks, and from 88 to 96.3% in the 679-L tanks, had inflated gas bladders. The outstanding rate of gas bladder inflation is attributed to the use of a surface spray, which seems to clear the water surface of oil and debris. These experiments demonstrate the feasibility of mass culture of larval walleyes in production-scale tanks.

Efficacy of Lumiracoxib in Osteoarthritis: A Review of Nine Studies

Journal of International Medical Research, 2005

Lumiracoxib is a cyclooxygenase-2 selective inhibitor in development for the treatment of osteoar... more Lumiracoxib is a cyclooxygenase-2 selective inhibitor in development for the treatment of osteoarthritis (OA), rheumatoid arthritis and acute pain. We reviewed nine clinical studies of 1 − 52 weeks' duration demonstrating the efficacy of lumiracoxib in OA. Male and female patients aged ≥ 18 years with primary OA of the hand, hip or knee received lumiracoxib, placebo or active comparators (diclofenac, celecoxib or rofecoxib). Lumiracoxib provided consistent reductions in OA pain intensity and improvements in the patient's global assessment of disease activity and functional status (assessed using the Western Ontario and McMaster Universities Osteoarthritis Index questionnaire or the Australian/Canadian OA Hand Index). These results were superior to placebo and similar to the active comparators tested. In addition, lumiracoxib was consistently superior to placebo and generally similar to active comparators in terms of the new Outcome Measures in Clinical Trials and Osteoarthri...

Pharmacological options in the management of orthostatic hypotension in older adults

Expert Review of Cardiovascular Therapy, 2009

Orthostatic hypotension (OH) is a common disorder in older adults with potentially serious clinic... more Orthostatic hypotension (OH) is a common disorder in older adults with potentially serious clinical consequences. Understanding the key underlying pathophysiological processes that predispose individuals to OH is essential when making treatment decisions for this group of patients. In this article, we discuss the key antihypotensive agents used in the management of OH in older adults. Commonly, midodrine is used as a first-line agent, given its supportive data in randomized, controlled trials. Fludrocortisone has been evaluated in open-label trials and has long-established usage in clinical practice. Other agents are available and in clinical use, either alone or in combination, but larger randomized trial evaluations are yet to be published. It is important to bear in mind that a patient may be taking medications that predispose to or exacerbate the symptoms of OH. Withdrawal of such medications, where possible, should be considered before commencing other pharmacological agents that attenuate the symptoms of OH.

High power continuous operation of laser diodes at 1064 nm

Electronics Letters, 1991

selfcalibrating) rate. The spectral noise current of M1 and of the switches at its drain is reduc... more selfcalibrating) rate. The spectral noise current of M1 and of the switches at its drain is reduced by the gain Acf) at frequency 1: As the corner frequency of Acf) is usually much higher than the llfnoise corner frequency of M1, the remaining high-frequency noise of M1 is mainly determined by thermal noise, if the current density is sufficiently low. The noise current of the basic current source Q1 can be expected to be considerably less than that of an MOS current source because surface effects are reduced even if Q1 is a lateral tran~istor.~ Attention should be paid to the noise of the circuit generating the base voltage which could be the limiting factor to accuracy. High output resistance rmt in the hold mode can be achieved even if M1 is operating in saturation. With g , and go being the transconductance and the output conductance of M1, respectively, it can approximately be expressed as

The FRIENDS Program for Young Former-Yugoslavian Refugees in Australia: A Pilot Study

Behaviour Change, 2000

Young immigrants frequently experience anxiety as a consequence of the stress associated with mig... more Young immigrants frequently experience anxiety as a consequence of the stress associated with migration. Despite being at high risk for the development of psychopathology, culturally sensitive assessment and intervention procedures for use with ethnic minority groups residing in Australia have yet to be developed and validated. The aims of the current study were to (a) investigate the level of anxiety in a sample of former-Yugoslavian teenage refugees; (b) appraise the efficacy of the FRIENDS program, a validated Anglo-Australian anxiety-prevention program, for use with this high-risk group; and (c) obtain information from both the program participants and facilitators regarding how the intervention could be modified to better meet the needs of this growing refugee population in Australia. Twenty female former-Yugoslavian youths completed standardised measures of internalising symptoms. Participants were allocated to either an intervention (n = 9) or a waiting list (n = 11) conditio...

Evaluation of Tank Shape and a Surface Spray for Intensive Culture of Larval Walleyes Fed Formulated Feed

The Progressive Fish-Culturist, 1994

... Evaluation of Tank Shape and a Surface Spray for Intensive Culture of Larval Walleyes Fed For... more