Ankara Üniversitesi Veteriner Fakültesi Dergisi, 1997
This sıudy was carried oul to detamine the effecıs of liquid methionine added lo the hroiler raıi... more This sıudy was carried oul to detamine the effecıs of liquid methionine added lo the hroiler raıions on live weight gain, feed ('onsumption, feed efficiency and carcass yield. A total of 175 daily HuMard hroiler chicks were used in this experiment. They were divided into one canırol group and six treatment groups each containing 25 chick.\'. The experimental period lasted six week.\'. The control ratian ıvas prepared with soybean meal+maize (basal ratian). The rations of the treatment groups were formulated with addition of O./ % liquid methionine (LM), 0.2 90 /_M, 2 % fish meal (FM), 2 % FM+O./ o/c LM, 2 % FM+0.2 % LM and 4 % FM to the basal ratian, respectively. At the end of the study, there were statistically significant dijferences among the groups in live \veight (p<O.Ol). Live weight gain of control group and trealment groups were found as /323.99, /53/.93, /637.5/, /567.74, J678.04, J800.58 and J6 / 5.09 g, re~pectively during six week.\' investigation period. Feed consumption per one kg live weight gain of groups during investigation were detennined as 2.70, 2.33, 2.04, 2.4 /, 2.38, 2.2/ and 2.56 kg, respectively. There were statistically significant dijferences among the groups in carcass weights and yields (p<O.OJ). At the end of the study, it is concluded that live weight gaiıı, feed efficiency aııd carcass yield \-vere positively infiueneed by addition of liquid methionine to the ration.~with or withoutfish meal in broilers.
Ankara Üniversitesi Veteriner Fakültesi Dergisi, 2009
In this paper schistosoma reflexum was reported with anatomical and pathological findings in a do... more In this paper schistosoma reflexum was reported with anatomical and pathological findings in a dog for the first time.
To investigate the action of N-acetylcysteine (NAC) on rat isolated ileal contractility, and to d... more To investigate the action of N-acetylcysteine (NAC) on rat isolated ileal contractility, and to determine the effects of NAC on histopathological changes on ileal tissue. The study took place at the Faculty of Medicine, Ankara University, Ankara, Turkey, in January 2003. Adult Wistar rats were used in all experiments. Two groups were designed. The experimental group, to which NAC 0.5 g/Kg/day was administered orally by adding to their water for 7 days, and the control group to which only saline was administered. At the end of the experimental periods, one cm pieces of terminal ileum segments were removed for testing ileal contractility, and one cm pieces of ileum segments were removed for histopathological experiments. The acetylcholine (ACh)-induced contraction was recorded, and the ileal tissue examined using light and electron microscopic technics for histopathological changes. The average peak amplitude of ACh-induced contraction recorded in standard tyrode solution of the exper...
... Önce ve Sonra Solunum Fonksiyon Testleri Ahmet ERGÜN*, Mustafa ŞIRLAK** ... Ameliyat sonrası,... more ... Önce ve Sonra Solunum Fonksiyon Testleri Ahmet ERGÜN*, Mustafa ŞIRLAK** ... Ameliyat sonrası, SFT volüm ve yüzde değerlerinde anlamlı azalma olurken (p&amp;lt; 0.001, p&amp;lt; 0.05), RV, %RV değerlerinde azal-ma ve %RV/TLC değerlerinde artış anlamlı bulunmadı (p&amp;gt; 0.05). ...
Ankara Üniversitesi Veteriner Fakültesi Dergisi, 2011
Bu araştırma broyler yemlerine biberiye (Rosemarinus officinalis) esansiyel yağ ve probiyotik (La... more Bu araştırma broyler yemlerine biberiye (Rosemarinus officinalis) esansiyel yağ ve probiyotik (Lactobacillus acidofilus, Lactobacillus casei, Enterococcus faecium, Bifidobacterium thermophilus) ilavesinin verim özellikleri, bazı kan parametreleri ve bağışıklık sistemi üzerine etkilerini belirlemek amacıyla yapılmıştır. Araştırmada hayvan materyali olarak toplam 272 adet erkek broyler civciv kullanılmıştır. Deneme her biri 68 erkek broyler civcivden oluşan 1 kontrol ve 3 deneme grubu olmak üzere toplam 4 grup halinde yürütülmüştür. Birinci, ikinci ve üçüncü deneme grupları rasyonlarına sırasıyla esansiyel yağ (200 mg/kg), probiyotik (0-21. günlerde 1 g/kg; 22-42. günlerde 0,5 g/kg) ve aynı düzeylerdeki esansiyel yağ ve probiyotik birlikte ilave edilmiştir. Kontrol grubu rasyonuna herhangi bir ilave yapılmamıştır. Araştırma 42 gün sürdürülmüştür. Araştırmanın sonunda esansiyel yağ ile esansiyel yağ ve probiyotiği birlikte içeren deneme gruplarında yem tüketimi düşmüş ve bu gruplarda yemden yararlanma daha iyi şekillenmiştir (p<0,01). Rasyona probiyotik ilave edilen grup, 0-21. günde canlı ağırlık artışını, sadece esansiyel yağ ilavesi yapılan gruba kıyasla arttırmıştır (p<0,05). Araştırmanın sonunda rasyona ilave edilen bileşenlerin canlı ağırlık, canlı ağırlık artışı, karkas randımanı, iç organ ağırlıkları ve abdominal yağ ağırlığı oranları, ince bağırsak pH'sı, kan serumunda toplam kolesterol ve trigliserit düzeyleri ve hümoral immun yanıt üzerine etkisi gözlenmemiştir. Anahtar kelimeler: Broyler, besi performansı, esansiyel yağ, probiyotik The effects of supplemental essential oil and/or probiotic on performance, immun System and some blood parameters in broilers Summary: This experiment was carried out to determine the effects of rosemary (Rosemarinus officinalis) essential oil and probiotic (Lactobacillus acidofilus, Lactobacillus casei, Enterococcus faecium, Bifidobacterium thermophilus) added to the broiler diets on performance characteristics, some blood parameters and immune system. A total of 272 male broiler chicks were used in this experiment. They were divided into one control group and three treatment group, totaly 4 group, each containing 68 male chicks. The diets of the first, second and third treatment groups were supplemented with 200 mg/kg essential oil, probiotic (1 g/kg days at 0-21; 0,5 g/kg days at 22-42) and combination of these two supplementation with same levels, respectively. There were not any supplementation to the diet of control group. The experimental period lasted 42 days. At the end of the experiment, dietary treatments which contained essential oil and essential oil with probiotic decreased feed intake and they had beter feed efficiency (p<0,01). Dietary probiotic supplemented group increased the body weight gain compared with only essential oil supplemented group (p<0,05) at 0-21 days. During the following weeks, no significant effects were observed for dietary probiotic supplementation on body weight gain. At the end of the experiment, body weight, body weight gain, carcass yield, percentages of some internal organs and abdominal fat, pH value of small intestine, total cholesterol, trigliceride of blood serum and humoral immun response were not effected by dietary supplements.
... (12:53) Sağlık yatırımı artık bir ... Medical Research Year: 1992 / Volume: 10 / No: 6. 17-21... more ... (12:53) Sağlık yatırımı artık bir ... Medical Research Year: 1992 / Volume: 10 / No: 6. 17-21 Yaş Grubunda Vücut Yağ Yüzdesinin Farklı İki Yöntemle Ölçülüp Karşılaştırılması Ahmet ERGÜN a , Serdar YARDIMCI a , Sema YAVUZER a , Ethem AKÇIL a a Ankara Üniversitesi Tıp ...
Aydınlık karanlık kutusu testi davranış fizyolojisinde kullanılan şartsız bir anksiyete testidir.... more Aydınlık karanlık kutusu testi davranış fizyolojisinde kullanılan şartsız bir anksiyete testidir. Bu derlemede aydınlık karanlık kutusu testinde bazı noktaları standardize etmek amacıyla biyolojik ve biyolojik olmayan faktörler açısından incelenmiştir.
Bu çalışma, Akdeniz Üniversitesi Tıp Fakültesi dönem 6 öğrencilerinin kullandıkları stresle başa ... more Bu çalışma, Akdeniz Üniversitesi Tıp Fakültesi dönem 6 öğrencilerinin kullandıkları stresle başa çıkma yöntemleri ve bu yöntemler ile ilişkili faktörleri incelemek amacıyla yapılmıştır. Gereç ve Yöntem: Eylül 2015'te yapılan kesitsel tipte bir araştırmadır. Araştırmanın evreni Akdeniz Üniversitesi Tıp Fakültesi 2015-2016 öğretim yılı içerisinde okuyan 226 dönem 6 öğrencisidir. Çalışmaya 181 öğrenci (%80,1) katılmıştır. "Stresle Başa Çıkma Tarzları Ölçeği" ve sosyodemografik soruları içeren anket ile veriler toplanmıştır. Veriler, SPSS 11,5 paket programı ile değerlendirilmiştir. Tüm katılımcıların puanlarının ortalaması ve standart sapması hesaplanmıştır. Gruplar arası farklılıkların tespitinde independent samples t-test kullanılmıştır. Anlamlılık düzeyi p<0.05 olarak belirlenmiştir. Bulgular: Katılımcıların en fazla "Sosyal Destek Arama", en az "Boyun Eğici Yaklaşım" yöntemini kullandığı saptanmıştır. Kadınların ve tıp fakültesini isteyerek tercih edenlerin "probleme yönelik/ aktif" tarzı, ailesinden ayrı yaşayanların ve tıp fakültesini kendisi isteyerek değil de yönlendirme sonucunda tercih edenlerin "duygulara yönelik/pasif" tarzı daha çok kullandıkları (p<0,05) görülmüştür. Sonuç: Öğrencilere eğitimleri sürecinde stresle başa çıkma tarzlarını olumlu yönde geliştirebilecekleri yöntemler anlatılmalı ve risk altındaki gruplara yönelik koruyucu yöntemler geliştirilmelidir.
Ankara Üniversitesi Veteriner Fakültesi Dergisi, 2009
The objective of this study was to characterize seasonal variations in serum concentrations of me... more The objective of this study was to characterize seasonal variations in serum concentrations of melatonin, testosterone, and progesterone in Arabian horses under natural photoperiodic conditions. Peripheral blood samples were collected during breeding and non-breeding seasons from mares and stallions. Serum concentrations of melatonin, testosterone, and progesterone were determined by radioimmunoassay. Serum concentrations of melatonin were greater in the non-breeding season (42.41±1.59 and 37.68±1.55 pg/ml) when compared to breeding season (23.52±1.24 and 17.22±2.10 pg/ml) in both mares and stallions, respectively. Melatonin concentrations were low but not different between the luteal and follicular phases during breeding season in cyclic mares. Mares had greater concentrations of melatonin than stallions in both breeding and non-breeding season. Mean concentrations of testosterone were greater during breeding season (6.58±0.50 ng/ml) than non-breeding season (3.64±0.48 ng/ml) in stallions. There was a negative correlation (r=-0.658, p<0.01) with melatonin and testosterone levels in both season in stallions. A negative correlation (r=-0.829, p<0.05) in luteal phase and a positive correlation (r=0.847, p<0.05) in non-breeding season were found between melatonin and progesterone concentrations in mares. We conclude that changes in day length act as a regulator and photoperiod can be used to modify the seasonal reproduction in Arabian horse.
Respiratory complications after successful CABG operation continuous to have on influence on the ... more Respiratory complications after successful CABG operation continuous to have on influence on the immediate recovery of a patient. It was reported that the mortality risk of the CABG patients increased, proportional to the reduction of pulmonary function tests (PFT). In the present study we aimed to investigate PFT values (vital capacity: VC, total lung capacity: TLC, residual volume: RV, functional residual capacity: FRC, force expiratory volume first second: FEV1, force mid expiratory flow: FEF25-75, duration force expiratory flow in vital capacity 25%: FEF25, duration force expiratory flow in vital capacity 50%: FEF50, duration force expiratory flow in vital capacity 75%: FEF75, peak expiratory flow: PEF, RV/TLC, FEF/FIF, FEV1/FVC) and arterial blood gases (pH, PaCO2, PaO2, SaO2) pre- and postoperatively which undergo CABG. The PFT and arterial blood gases values of 20 patients, age between 39-74 years, were measured that were undergo CABG operation before a week and three months ...
We conducted this study to identify the effect of subchronic cigarette smoke inhalation on the vo... more We conducted this study to identify the effect of subchronic cigarette smoke inhalation on the vocal cord mucosa of the rat. Experimental study. Department of Otolaryngology, School of Medicine, Karadeniz Technical University, Trabzon, Turkey Twenty-four male Wistar rats were divided randomly into experimental and control groups. The experimental group of rats was exposed to cigarette smoke for 2 hours each day over 60 consecutive days, and the control group was treated in an identical fashion but was exposed only to room air. Transmission electron microscopic examination of the rat vocal cords. We found very high levels of plasma thiocyanate after exposure to smoke in the experimental group but no increase in the control group. In the experimental group, mean plasma thiocyanate concentrations of 3.7 +/- 0.5 and 119 +/- 11.4 mmol/L were measured before and after exposure to tobacco smoke, respectively (p &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; .05). On the contrary, mean plasma thiocyanate levels of control rats were found to be 3.0 +/- 0.4 and 3.9 +/- 0.4 mmol/L, respectively, before and after exposure. In the experimental group, the epithelium covering the true vocal cords shows disturbed stratification. Some cells exhibit loss of desmosomal connections between cells and enlargement of the intercellular space. Our study demonstrates that the larynx in laboratory animals is one of the sensitive and useful targets for assessing the harmful effects associated with environmental tobacco smoke.
Ankara Üniversitesi Veteriner Fakültesi Dergisi, 1997
This sıudy was carried oul to detamine the effecıs of liquid methionine added lo the hroiler raıi... more This sıudy was carried oul to detamine the effecıs of liquid methionine added lo the hroiler raıions on live weight gain, feed ('onsumption, feed efficiency and carcass yield. A total of 175 daily HuMard hroiler chicks were used in this experiment. They were divided into one canırol group and six treatment groups each containing 25 chick.\'. The experimental period lasted six week.\'. The control ratian ıvas prepared with soybean meal+maize (basal ratian). The rations of the treatment groups were formulated with addition of O./ % liquid methionine (LM), 0.2 90 /_M, 2 % fish meal (FM), 2 % FM+O./ o/c LM, 2 % FM+0.2 % LM and 4 % FM to the basal ratian, respectively. At the end of the study, there were statistically significant dijferences among the groups in live \veight (p<O.Ol). Live weight gain of control group and trealment groups were found as /323.99, /53/.93, /637.5/, /567.74, J678.04, J800.58 and J6 / 5.09 g, re~pectively during six week.\' investigation period. Feed consumption per one kg live weight gain of groups during investigation were detennined as 2.70, 2.33, 2.04, 2.4 /, 2.38, 2.2/ and 2.56 kg, respectively. There were statistically significant dijferences among the groups in carcass weights and yields (p<O.OJ). At the end of the study, it is concluded that live weight gaiıı, feed efficiency aııd carcass yield \-vere positively infiueneed by addition of liquid methionine to the ration.~with or withoutfish meal in broilers.
Ankara Üniversitesi Veteriner Fakültesi Dergisi, 2009
In this paper schistosoma reflexum was reported with anatomical and pathological findings in a do... more In this paper schistosoma reflexum was reported with anatomical and pathological findings in a dog for the first time.
To investigate the action of N-acetylcysteine (NAC) on rat isolated ileal contractility, and to d... more To investigate the action of N-acetylcysteine (NAC) on rat isolated ileal contractility, and to determine the effects of NAC on histopathological changes on ileal tissue. The study took place at the Faculty of Medicine, Ankara University, Ankara, Turkey, in January 2003. Adult Wistar rats were used in all experiments. Two groups were designed. The experimental group, to which NAC 0.5 g/Kg/day was administered orally by adding to their water for 7 days, and the control group to which only saline was administered. At the end of the experimental periods, one cm pieces of terminal ileum segments were removed for testing ileal contractility, and one cm pieces of ileum segments were removed for histopathological experiments. The acetylcholine (ACh)-induced contraction was recorded, and the ileal tissue examined using light and electron microscopic technics for histopathological changes. The average peak amplitude of ACh-induced contraction recorded in standard tyrode solution of the exper...
... Önce ve Sonra Solunum Fonksiyon Testleri Ahmet ERGÜN*, Mustafa ŞIRLAK** ... Ameliyat sonrası,... more ... Önce ve Sonra Solunum Fonksiyon Testleri Ahmet ERGÜN*, Mustafa ŞIRLAK** ... Ameliyat sonrası, SFT volüm ve yüzde değerlerinde anlamlı azalma olurken (p&amp;lt; 0.001, p&amp;lt; 0.05), RV, %RV değerlerinde azal-ma ve %RV/TLC değerlerinde artış anlamlı bulunmadı (p&amp;gt; 0.05). ...
Ankara Üniversitesi Veteriner Fakültesi Dergisi, 2011
Bu araştırma broyler yemlerine biberiye (Rosemarinus officinalis) esansiyel yağ ve probiyotik (La... more Bu araştırma broyler yemlerine biberiye (Rosemarinus officinalis) esansiyel yağ ve probiyotik (Lactobacillus acidofilus, Lactobacillus casei, Enterococcus faecium, Bifidobacterium thermophilus) ilavesinin verim özellikleri, bazı kan parametreleri ve bağışıklık sistemi üzerine etkilerini belirlemek amacıyla yapılmıştır. Araştırmada hayvan materyali olarak toplam 272 adet erkek broyler civciv kullanılmıştır. Deneme her biri 68 erkek broyler civcivden oluşan 1 kontrol ve 3 deneme grubu olmak üzere toplam 4 grup halinde yürütülmüştür. Birinci, ikinci ve üçüncü deneme grupları rasyonlarına sırasıyla esansiyel yağ (200 mg/kg), probiyotik (0-21. günlerde 1 g/kg; 22-42. günlerde 0,5 g/kg) ve aynı düzeylerdeki esansiyel yağ ve probiyotik birlikte ilave edilmiştir. Kontrol grubu rasyonuna herhangi bir ilave yapılmamıştır. Araştırma 42 gün sürdürülmüştür. Araştırmanın sonunda esansiyel yağ ile esansiyel yağ ve probiyotiği birlikte içeren deneme gruplarında yem tüketimi düşmüş ve bu gruplarda yemden yararlanma daha iyi şekillenmiştir (p<0,01). Rasyona probiyotik ilave edilen grup, 0-21. günde canlı ağırlık artışını, sadece esansiyel yağ ilavesi yapılan gruba kıyasla arttırmıştır (p<0,05). Araştırmanın sonunda rasyona ilave edilen bileşenlerin canlı ağırlık, canlı ağırlık artışı, karkas randımanı, iç organ ağırlıkları ve abdominal yağ ağırlığı oranları, ince bağırsak pH'sı, kan serumunda toplam kolesterol ve trigliserit düzeyleri ve hümoral immun yanıt üzerine etkisi gözlenmemiştir. Anahtar kelimeler: Broyler, besi performansı, esansiyel yağ, probiyotik The effects of supplemental essential oil and/or probiotic on performance, immun System and some blood parameters in broilers Summary: This experiment was carried out to determine the effects of rosemary (Rosemarinus officinalis) essential oil and probiotic (Lactobacillus acidofilus, Lactobacillus casei, Enterococcus faecium, Bifidobacterium thermophilus) added to the broiler diets on performance characteristics, some blood parameters and immune system. A total of 272 male broiler chicks were used in this experiment. They were divided into one control group and three treatment group, totaly 4 group, each containing 68 male chicks. The diets of the first, second and third treatment groups were supplemented with 200 mg/kg essential oil, probiotic (1 g/kg days at 0-21; 0,5 g/kg days at 22-42) and combination of these two supplementation with same levels, respectively. There were not any supplementation to the diet of control group. The experimental period lasted 42 days. At the end of the experiment, dietary treatments which contained essential oil and essential oil with probiotic decreased feed intake and they had beter feed efficiency (p<0,01). Dietary probiotic supplemented group increased the body weight gain compared with only essential oil supplemented group (p<0,05) at 0-21 days. During the following weeks, no significant effects were observed for dietary probiotic supplementation on body weight gain. At the end of the experiment, body weight, body weight gain, carcass yield, percentages of some internal organs and abdominal fat, pH value of small intestine, total cholesterol, trigliceride of blood serum and humoral immun response were not effected by dietary supplements.
... (12:53) Sağlık yatırımı artık bir ... Medical Research Year: 1992 / Volume: 10 / No: 6. 17-21... more ... (12:53) Sağlık yatırımı artık bir ... Medical Research Year: 1992 / Volume: 10 / No: 6. 17-21 Yaş Grubunda Vücut Yağ Yüzdesinin Farklı İki Yöntemle Ölçülüp Karşılaştırılması Ahmet ERGÜN a , Serdar YARDIMCI a , Sema YAVUZER a , Ethem AKÇIL a a Ankara Üniversitesi Tıp ...
Aydınlık karanlık kutusu testi davranış fizyolojisinde kullanılan şartsız bir anksiyete testidir.... more Aydınlık karanlık kutusu testi davranış fizyolojisinde kullanılan şartsız bir anksiyete testidir. Bu derlemede aydınlık karanlık kutusu testinde bazı noktaları standardize etmek amacıyla biyolojik ve biyolojik olmayan faktörler açısından incelenmiştir.
Bu çalışma, Akdeniz Üniversitesi Tıp Fakültesi dönem 6 öğrencilerinin kullandıkları stresle başa ... more Bu çalışma, Akdeniz Üniversitesi Tıp Fakültesi dönem 6 öğrencilerinin kullandıkları stresle başa çıkma yöntemleri ve bu yöntemler ile ilişkili faktörleri incelemek amacıyla yapılmıştır. Gereç ve Yöntem: Eylül 2015'te yapılan kesitsel tipte bir araştırmadır. Araştırmanın evreni Akdeniz Üniversitesi Tıp Fakültesi 2015-2016 öğretim yılı içerisinde okuyan 226 dönem 6 öğrencisidir. Çalışmaya 181 öğrenci (%80,1) katılmıştır. "Stresle Başa Çıkma Tarzları Ölçeği" ve sosyodemografik soruları içeren anket ile veriler toplanmıştır. Veriler, SPSS 11,5 paket programı ile değerlendirilmiştir. Tüm katılımcıların puanlarının ortalaması ve standart sapması hesaplanmıştır. Gruplar arası farklılıkların tespitinde independent samples t-test kullanılmıştır. Anlamlılık düzeyi p<0.05 olarak belirlenmiştir. Bulgular: Katılımcıların en fazla "Sosyal Destek Arama", en az "Boyun Eğici Yaklaşım" yöntemini kullandığı saptanmıştır. Kadınların ve tıp fakültesini isteyerek tercih edenlerin "probleme yönelik/ aktif" tarzı, ailesinden ayrı yaşayanların ve tıp fakültesini kendisi isteyerek değil de yönlendirme sonucunda tercih edenlerin "duygulara yönelik/pasif" tarzı daha çok kullandıkları (p<0,05) görülmüştür. Sonuç: Öğrencilere eğitimleri sürecinde stresle başa çıkma tarzlarını olumlu yönde geliştirebilecekleri yöntemler anlatılmalı ve risk altındaki gruplara yönelik koruyucu yöntemler geliştirilmelidir.
Ankara Üniversitesi Veteriner Fakültesi Dergisi, 2009
The objective of this study was to characterize seasonal variations in serum concentrations of me... more The objective of this study was to characterize seasonal variations in serum concentrations of melatonin, testosterone, and progesterone in Arabian horses under natural photoperiodic conditions. Peripheral blood samples were collected during breeding and non-breeding seasons from mares and stallions. Serum concentrations of melatonin, testosterone, and progesterone were determined by radioimmunoassay. Serum concentrations of melatonin were greater in the non-breeding season (42.41±1.59 and 37.68±1.55 pg/ml) when compared to breeding season (23.52±1.24 and 17.22±2.10 pg/ml) in both mares and stallions, respectively. Melatonin concentrations were low but not different between the luteal and follicular phases during breeding season in cyclic mares. Mares had greater concentrations of melatonin than stallions in both breeding and non-breeding season. Mean concentrations of testosterone were greater during breeding season (6.58±0.50 ng/ml) than non-breeding season (3.64±0.48 ng/ml) in stallions. There was a negative correlation (r=-0.658, p<0.01) with melatonin and testosterone levels in both season in stallions. A negative correlation (r=-0.829, p<0.05) in luteal phase and a positive correlation (r=0.847, p<0.05) in non-breeding season were found between melatonin and progesterone concentrations in mares. We conclude that changes in day length act as a regulator and photoperiod can be used to modify the seasonal reproduction in Arabian horse.
Respiratory complications after successful CABG operation continuous to have on influence on the ... more Respiratory complications after successful CABG operation continuous to have on influence on the immediate recovery of a patient. It was reported that the mortality risk of the CABG patients increased, proportional to the reduction of pulmonary function tests (PFT). In the present study we aimed to investigate PFT values (vital capacity: VC, total lung capacity: TLC, residual volume: RV, functional residual capacity: FRC, force expiratory volume first second: FEV1, force mid expiratory flow: FEF25-75, duration force expiratory flow in vital capacity 25%: FEF25, duration force expiratory flow in vital capacity 50%: FEF50, duration force expiratory flow in vital capacity 75%: FEF75, peak expiratory flow: PEF, RV/TLC, FEF/FIF, FEV1/FVC) and arterial blood gases (pH, PaCO2, PaO2, SaO2) pre- and postoperatively which undergo CABG. The PFT and arterial blood gases values of 20 patients, age between 39-74 years, were measured that were undergo CABG operation before a week and three months ...
We conducted this study to identify the effect of subchronic cigarette smoke inhalation on the vo... more We conducted this study to identify the effect of subchronic cigarette smoke inhalation on the vocal cord mucosa of the rat. Experimental study. Department of Otolaryngology, School of Medicine, Karadeniz Technical University, Trabzon, Turkey Twenty-four male Wistar rats were divided randomly into experimental and control groups. The experimental group of rats was exposed to cigarette smoke for 2 hours each day over 60 consecutive days, and the control group was treated in an identical fashion but was exposed only to room air. Transmission electron microscopic examination of the rat vocal cords. We found very high levels of plasma thiocyanate after exposure to smoke in the experimental group but no increase in the control group. In the experimental group, mean plasma thiocyanate concentrations of 3.7 +/- 0.5 and 119 +/- 11.4 mmol/L were measured before and after exposure to tobacco smoke, respectively (p &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; .05). On the contrary, mean plasma thiocyanate levels of control rats were found to be 3.0 +/- 0.4 and 3.9 +/- 0.4 mmol/L, respectively, before and after exposure. In the experimental group, the epithelium covering the true vocal cords shows disturbed stratification. Some cells exhibit loss of desmosomal connections between cells and enlargement of the intercellular space. Our study demonstrates that the larynx in laboratory animals is one of the sensitive and useful targets for assessing the harmful effects associated with environmental tobacco smoke.
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