Papers by Adeniyi Bamidele
Journal of Asthma, 2013
Objective: Lung function measurements performed several times daily are useful for the diagnosis ... more Objective: Lung function measurements performed several times daily are useful for the diagnosis of occupational asthma. Patient fabrication of hand-recorded charts can limit confidence in the results; this is overcome using electronic meters that log time and measurement. We have compared individual and meter differences in FEV1 and PEF recorded by hand and from meter logs using expert subjects on four data-logging spirometers with different methods of measurement and different quality control software. Methods: Eight workers in a respiratory physiology department were asked to record FEV1 and PEF 2-hourly from waking for 7 days using four electronic meters (Easyone, Micro DL, Vitalograph Diary card 2110 and Piko-1) in random order. Subjects hand-recorded the best FEV1 and PEF from each session, this was compared with the logged data. Results: Discordant measurements from individuals were lower for FEV1 than PEF and differed from 4.4-19.1% for FEV1 (mean 9.4%, p50.0001) and 6-23.3% for PEF (mean 12.6, p50.0001). There were also significant differences between meters for both variables (p50.0001). The magnitude of the differences in PEF was highest for the Easyone (34l/min) and lowest for the Vitalograph Diary card 2110 (14l/min) and varied significantly between meters (mean 22l/min, p ¼ 0.002). Conclusions: Differences between hand-recorded and logged measurements are unlikely to be due solely to patient fabrication and can be due to quality criteria or other unclear software requirements applied after the results are shown on the meter screen; they differ between meters. Whether the differences shown affect clinical outcome will require further investigation.
Annals of the American Thoracic Society, 2017
Black Africans have reduced FVC compared with white persons, but the prevalence and determinants ... more Black Africans have reduced FVC compared with white persons, but the prevalence and determinants of reduced values are not well understood. To evaluate the prevalence and factors leading to reduced FVC in a Nigerian population and to examine current theories regarding the determinants of this difference. We studied the ventilatory function of 883 adults aged 40 years or older participating in the Burden of Obstructive Lung Disease Study in Ile-Ife, Nigeria. Respondents completed pre- and post-bronchodilator spirometry test and provided information on their smoking history, respiratory symptoms, risk factors, and diagnoses, including anthropometric details. We used standard categories to define body mass index as either underweight, normal, overweight, or obese. We defined reduced FVC as a post-bronchodilator FVC below the lower limit of normal using National Health and Nutrition Examination Survey (NHANES) equations, Global Lung Function Initiative 2012 equations, and local referenc...
Health related quality of life and psychological variables among a sample of asthmatics in Ile-If... more Health related quality of life and psychological variables among a sample of asthmatics in Ile-Ife South-
Objective: Exposures to petrol vapours have been shown to affect functioning of different systems... more Objective: Exposures to petrol vapours have been shown to affect functioning of different systems of the body. The effect on lung function is largely unexplored in Africa. We aimed at studying the effect of exposure to petrol vapours on pulmonary function among petrol pump workers. Method: A cross-sectional survey using modified Medical Research Council questionnaire was conducted and spirometry was carried out after a typical work shift in exposed petrol pump attendants and security guards in a university hospital as controls. Result: The pre-bronchodilator percent predicted forced vital capacity and post bronchodilator percent predicted forced vital capacity were significantly lower for the exposed vs controls 83.4±12.2;87.2±11.9 and 83.9±12.4;87.7±12.3 (p=0.031 and 0.036 respectively). Conclusion: Exposure to petrol fumes of petrol pump workers may result in significantly lower lung function when compared with age and sex-matched controls.
Background: Bronchial Asthma is a disease with increasing global significance. Its prevalence is ... more Background: Bronchial Asthma is a disease with increasing global significance. Its prevalence is projected to increase to 400 million by the year 2025 as compared to the present estimate of 300 million. Previously asthma was assessed mainly in terms of symptoms and measures of lung functions but more recently these indices have not been able to reflect the true state of the asthmatics. The focus is now shifting to an assessment and treatment approach based on control. Asthma Control Test (ACT) is a validated, simple and inexpensive instrument to assess control among patients with bronchial asthma. However, its relationship with lung function parameters is yet to be demonstrated among Nigerian asthmatic patients. Aim: The study aimed at assessing asthma control using ACT scores and to determine its relationship with lung function parameters among persons with asthma in a university respiratory clinic.
Libyan Journal of Medicine, 2011
Background: Assessment of health related quality of life (HRQL) has become central to assessing t... more Background: Assessment of health related quality of life (HRQL) has become central to assessing the selfperceived impact of physical and mental impairment on patient's health. Studies have reported a high rate of psychological disturbances among asthmatics; however, the impact of these psychological factors on HRQL remains unexplored. Objectives: To assess the health related quality of life among a sample of asthmatics and to identify the psychological and clinical variables that affect quality of life among asthmatics. Method: A total of 81 patients attending the clinic were assessed using the Mini-Asthma Quality of Life questionnaire (Mini-AQLQ), and the Hospital Anxiety and Depression Scale (HADS). Sociodemographic and clinical variables were also obtained from the patients, the lung function was assessed using Peak Expiratory Flow Rate (PEFR). Results: Mean age of all the patients was 35.22 (SD914.36) with a mean duration of asthma symptoms of 17.5 (SD914.4) years. Mean peak expiratory flow was 336 l/min (SD974.12). Anxiety was present in 44.4% of respondents, while 40% of respondents reported the presence of depressive symptoms, 48.1% of the respondents reported low scores on the asthma quality of life questionnaire. Poor quality of life was associated with the presence of psychological symptoms, female sex, and lower educational level. Conclusion: Psychosocial variables are just as important as clinical variables as determinants of health related quality of life among asthmatics.
In Nigeria, as in most countries in sub-Saharan Africa, patients do not present early enough unti... more In Nigeria, as in most countries in sub-Saharan Africa, patients do not present early enough until complications start to set in and exercise limitation is becoming marked.
Objective: Exposures to petrol vapours have been shown to affect functioning of different systems... more Objective: Exposures to petrol vapours have been shown to affect functioning of different systems of the body. The effect on lung function is largely unexplored in Africa. We aimed at studying the effect of exposure to petrol vapours on pulmonary function among petrol pump workers. Method: A cross-sectional survey using modified Medical Research Council questionnaire was conducted and spirometry was carried out after a typical work shift in exposed petrol pump attendants and security guards in a university hospital as controls. Result: The pre-bronchodilator percent predicted forced vital capacity and post bronchodilator percent predicted forced vital capacity were significantly lower for the exposed vs controls 83.4±12.2;87.2±11.9 and 83.9±12.4;87.7±12.3 (p=0.031 and 0.036 respectively). Conclusion: Exposure to petrol fumes of petrol pump workers may result in significantly lower lung function when compared with age and sex-matched controls.
Background: Respiratory diseases constitute a large percentage of the medical conditions requirin... more Background: Respiratory diseases constitute a large percentage of the medical conditions requiring hospital presentation. The burden of respiratory diseases presenting as emergencies need to be understood. Objective: This study aimed at reviewing the pattern of respiratory diseases in the emergency unit of Federal Medical Centre, Owo. Methods: The records of 914 patients seen with respiratory diseases from January 2007 to December 2012 were reviewed. Data were analyzed using SPSS version 21. Descriptive statistics were done. Chi-square test was used to compare other sociodemographic characteristics and disease-related variables by gender. Level of statistical significant was 5%. Results: The mean age of respondents was 46.5 ± 20 years, 54.9% were 40 years and above. Males were 57.9%, 24% presented as acute conditions, 10.4% were Human immunodeficiency virus, HIV-positive. Death occurred in 7.1% within 24 h of admission. Median length of stay was 1.9 ± 1.4 days. Complicated pulmonary tuberculosis (PTB) was diagnosed in 35.1% of the patients followed by pneumonias (26.9%) and acute severe asthma (18.4%). The mean age of male patient was 48.5 ± 20.4 years while female was 43.8 ± 18.9 years, males are significantly older than females P < 0.001. Patients with HIV were younger with mean age 35.9 ± 10.4 years compared with HIV-negative patients, 47.8 ± 20.3 years P < 0.001. More females (13.8%) were HIV-positive compared to males (7.9%), P = 0.004. Conclusion: Complicated PTB and the pneumonias were the leading causes of respiratory emergency in our environment. Not all respiratory cases seen at the emergency were acute condition. Standard precaution should be ensured as every one out of ten patients seen were HIV-positive. Disparities exist in the pattern of respiratory disease across gender.
Introduction: Adequate knowledge of asthma management and adherence to international guidelines a... more Introduction: Adequate knowledge of asthma management and adherence to international guidelines are known to increase the quality of care offered by Physicians. We conducted this study to assess the level of asthma knowledge and quality of care among physicians practicing in Ondo State. Methods: We conducted a cross sectional survey of 96 physicians from various specialties participating in a continuous professional development (CPD) lecture using adapted questionnaires. Result: Respondents ranged in age from 23-62years (42.5±19.4). There were more male (70%). The minority (17%) had additional postgraduate medical qualifications. There was a high distribution of correct answers for individual knowledge questions. The greatest areas of knowledge gaps appeared in diagnostic instruments, asthma severity and drugs. We observed gaps regarding the use of GINA guidelines (6%) and prescribing combined inhaled steroid and long acting bronchodilator for patients who are not controlled on inhaled steroid alone (29%). A large number of the respondents do not confirm the diagnosis of asthma by spirometry (32%). Only 8% of the respondents with high knowledge reported a corresponding high quality of Asthma care. Conclusion: We concluded that although physicians in South-West Nigeria appear to have good knowledge, there are areas of gap in the quality of asthma care with regards to standard guideline. There is need for constant training and re-training of physicians in order to keep them up to date with international guidelines. In addition, increase access to diagnostic facilities and adapting international guideline to local realities will help improve standard of Asthma care.
Background: Assessment of health related quality of life (HRQL) has become central to assessing t... more Background: Assessment of health related quality of life (HRQL) has become central to assessing the selfperceived impact of physical and mental impairment on patient's health. Studies have reported a high rate of psychological disturbances among asthmatics; however, the impact of these psychological factors on HRQL remains unexplored. Objectives: To assess the health related quality of life among a sample of asthmatics and to identify the psychological and clinical variables that affect quality of life among asthmatics. Method: A total of 81 patients attending the clinic were assessed using the Mini-Asthma Quality of Life questionnaire (Mini-AQLQ), and the Hospital Anxiety and Depression Scale (HADS). Sociodemographic and clinical variables were also obtained from the patients, the lung function was assessed using Peak Expiratory Flow Rate (PEFR). Results: Mean age of all the patients was 35.22 (SD914.36) with a mean duration of asthma symptoms of 17.5 (SD914.4) years. Mean peak expiratory flow was 336 l/min (SD974.12). Anxiety was present in 44.4% of respondents, while 40% of respondents reported the presence of depressive symptoms, 48.1% of the respondents reported low scores on the asthma quality of life questionnaire. Poor quality of life was associated with the presence of psychological symptoms, female sex, and lower educational level. Conclusion: Psychosocial variables are just as important as clinical variables as determinants of health related quality of life among asthmatics.
Background: Bronchial Asthma is a disease with increasing global significance. Its prevalence is ... more Background: Bronchial Asthma is a disease with increasing global significance. Its prevalence is projected to increase to 400 million by the year 2025 as compared to the present estimate of 300 million. Previously asthma was assessed mainly in terms of symptoms and measures of lung functions but more recently these indices have not been able to reflect the true state of the asthmatics. The focus is now shifting to an assessment and treatment approach based on control.
There are unmet needs for respiratory medical care in developing countries. We sought to evaluate... more There are unmet needs for respiratory medical care in developing countries. We sought to evaluate the quality and capacity for respiratory care in low-and lower-middle-income countries, using Nigeria as a case study. We obtained details of the respiratory practice of consultants and senior residents (fellows) in respiratory medicine in Nigeria via a semistructured questionnaire administered to physician attendees at the 2013 National Congress of the Nigerian Thoracic Society. Out of 76 society-registered members, 48 attended the congress, 40 completed the questionnaire, and 35 provided complete data (73% adjusted response rate). Respondents provided information on the process and costs of respiratory medicine training and facility, equipment, and supply capacities at the institutions they represented. Approximately 83% reported working at a tertiary level (teaching) hospital; 91% reported capacity for sputum smear analysis for acid alcohol-fast bacilli, 37%
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Papers by Adeniyi Bamidele