Papers by Abbas Rezaianzadeh
Clinical neurology and neurosurgery, 2014
Multiple sclerosis (MS) is the most common chronic autoimmune demyelinating disease of the centra... more Multiple sclerosis (MS) is the most common chronic autoimmune demyelinating disease of the central nervous system. The purpose of this study is to determine the relationship between the site of the cervical discopathy and cervical spinal cord plaque in MS patients. This retrospective study included all patients with a definite diagnosis of MS who were treated at an outpatient clinic between September 2004 and September 2011. All patients underwent cervical magnetic resonance imaging (MRI) for primary investigation of the disease. Cervical MRI scans were evaluated for detection of any evidence of cervical discopathy and cervical MS plaques. Any correlation between the site of the MS lesions and discopathy was recorded. From 536 patients who were involved in the study, 214 patients had both cervical discopathy and cervical cord plaques. In this group 148 (69.1% of patients) had cervical plaque at the same site of cervical discopathy. The number of patients with cervical cord plaque an...
Eastern Mediterranean health journal = La revue de santé de la Méditerranée orientale = al-Majallah al-ṣiḥḥīyah li-sharq al-mutawassiṭ
We carried out a cross-sectional survey in Shiraz to determine the prevalence of hepatitis C viru... more We carried out a cross-sectional survey in Shiraz to determine the prevalence of hepatitis C virus (HCV) in 1 444 individuals infected with human immunodeficiency virus (HIV). We also determined the risk factors for this coinfection. Demographic and behavioural data were obtained using a standard questionnaire. The prevalence of HIV-HCV coinfection was 78.4% (95% CI: 76.3-80.5). Intravenous drug use (OR = 7.2; 95% CI: 4.9-10.6), imprisonment (OR = 6.9; 95% CI: 4.6-10.4), tattooing in prison (OR = 2.61; 95% CI: 1.4-4.8), tattooing out of prison (OR = 2.0; 95% CI: 1.3-3.1) and age (OR = 1.02 with increasing each year of life; 95% CI: 1.0-1.04) were significantly associated with HCV-HIV coinfection. Prevalence of HCV-HIV coinfection is high in Shiraz. Intravenous drug use and imprisonment are the main risk factors for this coinfection. Therefore, serious implementation of HIV and HCV testing, education, prevention, care and treatment programmes and evaluation of harm reduction programm...
Archives of Disease in Childhood, 2012
Asian Pacific journal of cancer prevention : APJCP, 2014
The incidence rate of breast cancer in developed countries is almost three-fold higher than in de... more The incidence rate of breast cancer in developed countries is almost three-fold higher than in developing countries. Iran has had one of the lowest incidence rates for breast cancer in the world, but during the recent decades a marked increase has been seen. The purpose of this study was to investigate some established risk factors of breast cancer in Iranian women. A study of 11,850 women participating in abreast screening program was conducted. The 197 women diagnosed with breast cancer and 11,653 healthy women were compared. Logistic regression was performed to investigate associations of reproductive and anthropometric factors with breast cancer risk. Family history of breast cancer (OR=1.94 , 95%CI=1.35-2.78), occupation (OR= 1.65,95%CI=1.20- 2.25), education level (OR=0.50,95%CI=0.28-0.91), parity (OR=0.27, 95%CI=0.12-0.59), menopausal status (OR=3.15, 95%CI=2.35-4.21), age at menarche (OR=0.33, 95%CI=0.15-0.70), and age at the first pregnancy (OR=4.10 , 95%CI=1.13-14.77) were...
Asian Pacific journal of cancer prevention : APJCP, 2014
Around 200,000 breast disorders are annually diagnosed all over the world. Fibrocystic changes ar... more Around 200,000 breast disorders are annually diagnosed all over the world. Fibrocystic changes are the most common breast disorder and fibroadenoma is the most prevalent benign breast tumor. The present study aimed to determine the spectrum, type and prevalence of breast masses in women referred to Shiraz University of Medical Sciences between 2004 and 2012 . A cross-sectional study was conducted on the diagnostic reports data. A total of 640 samples were studied. Most 57.3% of masses were detected in the left breast, 65%, 28.2% and 6.1% of cases presenting with benign, malignant, and inflammatory lesions, respectively. Among all the samples the most prevalent diagnosis (37.7%) was fibroadenoma and fibrocystic lesions (17%). 174 samples (96% of the malignant cases) were invasive. 6.5% of the benign, and 37% of the malignant cases occurred in post menopause women and the differences were statistically significant. Among those with malignant tumors lymph nodes were involved in 25.6% o...
Acta medica Iranica, 2014
Recent studies in animal models indicate that recombinant human erythropoietin (rhEPO) is very ef... more Recent studies in animal models indicate that recombinant human erythropoietin (rhEPO) is very effective in enhancing neurological recovery after spinal cord injury (SCI). We aimed to evaluate the effect of rhEPO plus methylprednisolone sodium succinate (MPSS) compared to MPSS alone to improve neurological function of patients after SCI in a randomized clinical trial. During a 15-month period 30 patients presenting to emergency departments of two university affiliated hospitals within less than 6 hours after acute SCI were randomized to two groups. Both groups received MPSS 30 mg/kg initially and 5.4 mg/kg every hour till 23 hours if admitted within 3 hours and till 47 hours if recruited within 3-6 hours after injury. Group EPO also received 500 unit/kg rhEPO on admission and another 500 unit/kg 24 hours later instead of placebo in group MPSS. Neurologic evaluation was performed on admission, 24, 48, 72 hours and one and 6 months later. Range of patients' age was 18-65 years. Th...
World journal of plastic surgery, 2012
Breast cancer is still considered as one of the most common female cancers worldwide regardless o... more Breast cancer is still considered as one of the most common female cancers worldwide regardless of the countries' level of development. This study determines the incidence of breast cancer in Fars Province, Southern Iran. This study used patients' records from Shiraz University of Medical Sciences Cancer Registry Centre, which is a Hospital-Based Registry of Nemazee Hospital. Data were recorded based on International Classification of Diseases for Oncology (ICD-O) and compromised all invasive cancers in ICD-10 categories of C-00 to C-80. The findings were shown as the number of cases by site (ICD-10) and gender, with crude incidence (CRs), age-specific incidence and age-standardized incidence rates (ASRs) per 100,000 persons per year, performed by direct method using the world standard population. The age group of 40-49 years had the highest rate of breast cancer and naturally most cases were post-menopause ones. Most cases were diagnosed in moderate differentiated state wit...
Iranian journal of medical sciences, 2015
Protein-energy malnutrition (PEM) is a common complication in pediatric patients with chronic kid... more Protein-energy malnutrition (PEM) is a common complication in pediatric patients with chronic kidney disease (CKD). Components incorporated in the regulation of appetite and body composition appear to be of the focus in renal insufficiency and may influence the CKD-associated PEM. The purpose of this study was to investigate plasma levels of appetite-regulating hormones and their correlation with the body composition variables in a pediatric in predialysis stage of CKD. Thirty children with CKD in predialysis stage were selected and compared with 30 healthy sex- and age-matched controls. Blood samples were collected in fasting. Serum total ghrelin, leptin, and obestatin levels were measured using enzyme immunometric assay methods. Anthropometric parameters measurement and body composition analysis were done using the bioelectric impedance analysis (BIA) method. Patients showed insignificant elevated total ghrelin (105.40±30.83 ng/l), leptin (5.32±1.17 ng/ml) and obestatin (5.07±1.09...
Eastern Mediterranean health journal = La revue de santé de la Méditerranée orientale = al-Majallah al-ṣiḥḥīyah li-sharq al-mutawassiṭ, 2013
We carried out a cross-sectional survey in Shiraz to determine the prevalence of hepatitis C viru... more We carried out a cross-sectional survey in Shiraz to determine the prevalence of hepatitis C virus (HCV) in 1 444 individuals infected with human immunodeficiency virus (HIV). We also determined the risk factors for this coinfection. Demographic and behavioural data were obtained using a standard questionnaire. The prevalence of HIV-HCV coinfection was 78.4% (95% CI: 76.3-80.5). Intravenous drug use (OR = 7.2; 95% CI: 4.9-10.6), imprisonment (OR = 6.9; 95% CI: 4.6-10.4), tattooing in prison (OR = 2.61; 95% CI: 1.4-4.8), tattooing out of prison (OR = 2.0; 95% CI: 1.3-3.1) and age (OR = 1.02 with increasing each year of life; 95% CI: 1.0-1.04) were significantly associated with HCV-HIV coinfection. Prevalence of HCV-HIV coinfection is high in Shiraz. Intravenous drug use and imprisonment are the main risk factors for this coinfection. Therefore, serious implementation of HIV and HCV testing, education, prevention, care and treatment programmes and evaluation of harm reduction programm...
Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences, 2013
The cesarean section (C-section) has higher risk compared to normal vaginal delivery (NVD). The a... more The cesarean section (C-section) has higher risk compared to normal vaginal delivery (NVD). The aim of this population-based study was to evaluate the frequency of mothers' tendency toward the mode of delivery and the factors that can affect this inclination. This cross-sectional study was conducted from August 2011 to June 2012 in Fars Province, Iran, and comprised mothers in their 20(th) to 30(th) weeks of pregnancy. A questionnaire was designed to include, sociodemographic information, maternal knowledge, main sources of knowledge, attitude of the mother, husband, parents, close friends, and gynecologist, regarding the route of delivery, convenience factors, and barriers to choosing NVD, and mother's preference for the route of delivery. Of 6921 participants, 2197 (31.7%) preferred C-section and 4308 (62.2%) favored NVD while 416 (6%) had no idea regarding the preferred route of delivery. Score of knowledge in 904 (13.1%) participants was zero, and 1261 women (18.2%) achi...
Annals of Saudi medicine
Other than its classic presentation, celiac disease can be completely asymptomatic in a proportio... more Other than its classic presentation, celiac disease can be completely asymptomatic in a proportion of the general population. Subjects with silent celiac disease are at risk of potential complications of the disease, which indicates the importance of early diagnosis. In this study we investigated the prevalence of silent celiac disease in healthy children in our area. Cross-sectional screening of healthy children in Shiraz city. Fifteen hundred school children, 6 to 12 years of age in Shiraz (Southern Iran) were screened for celiac disease through serological testing of their serum anti-tissue transglutaminase immunoglobulin A antibodies. A small intestinal biopsy was performed for children with positive serology tests and pathologic reports were given according to the modified Marsh criteria. Of the total students included, with a mean (SD) age of 9.5 (1.3) years, 30 subjects had positive anti-tissue transglutaminase immunoglobulin A antibodies, resulting in a total seropositivity ...
Asian Pacific journal of cancer prevention : APJCP, 2012
Identification of simple and measurable prognostic factors is an important issue in treatment eva... more Identification of simple and measurable prognostic factors is an important issue in treatment evaluation of breast cancer. The present study was conducted to evaluate the prognostic role of vascular invasion in lymph node negative breast cancer patients. in a retrospective design, we analyzed the recorded profiles of the 1,640 patients treated in the breast cancer department of Motahari clinic affiliated to Shiraz University of Medical Sciences, Shiraz, Iran, from January 1999 to December 2012. Overall and adjusted survivals were evaluated by the Cox proportional hazard model. All the hypotheses were considered two-sided and a p-value of 0.05 or less was considered as statistically significant. Mean age in lymph node negative and positive patients was 50.0 and 49.8 respectively. In lymph node negative patients, the number of nodes, tumor size, lymphatic invasion, vascular invasion, progesterone receptor, and nuclear grade were significant predictors. In lymph node and lymphatic nega...
Journal of research in health sciences, 2012
Cox proportional hazard (CPH) model is the most widely used model for survival analysis. When the... more Cox proportional hazard (CPH) model is the most widely used model for survival analysis. When there are unobserved/unmeasured individuals factor, then the results of the Cox proportional hazard model may not be reliable. The purpose of this study was to compare the results of CPH and frailty models in breast cancer (BC) patients. A historical cohort study was carried out using medical records gathered from the Fars Province Cancer Registry. The dataset consisted of 769 women having BC referred to Shiraz Namazi Hospital, south of Iran. These patients had been followed for 6 years. After selecting the most important prognostic risk factors on survival, CPH and gamma-frailty Cox models were used to estimate the effects of the risk factors. The results of CPH model showed that, tumor characteristics and number of involved lymph nodes increase the mortality hazard of BC(P<0.05). In addition, the frailty model showed that there is at least a latent factor in the model (P=0.005). Both o...
Iranian journal of medical sciences, 2012
To provide effective health services, it is important to distinguish populations of people with a... more To provide effective health services, it is important to distinguish populations of people with and without diseases. Accurate diagnosis of diseases is important for delivering the appropriate treatments, implementing preventive programs in the community, and finding ...
Iranian Red Crescent medical journal, 2011
Prevalence of breast cancer in Asian developing countries is much lower than western developed co... more Prevalence of breast cancer in Asian developing countries is much lower than western developed countries. The main aim of this study was to measure breast cancer prevalence in a defined population of Iran. A total of 25201 women who were under coverage of "Imam Khomeini Relief Foundation (IKRF)", which is an organization for delivering supportive social and cultural services to the deprived and poor subgroups of the society, were involved in the study. The study was conducted during years 2007 and 2008. All subjects were interviewed for their socio-demographic features and underwent precise clinical and para-clinical breast examination. Mean age was 47 years with standard deviation 10 ranging from 11 to 88 years. Subjects were from deprived subgroups of the community; were mainly illiterate or had primary school education (86%) and majority of them (93%) had their first full-term pregnancy at age less than 26 years and also were multiparous. With confirmed diagnosis by bre...
BMC Infectious Diseases, 2014
Background: Overall, 60-70% of the hepatitis c virus (HCV) transmission routes is parenteral, and... more Background: Overall, 60-70% of the hepatitis c virus (HCV) transmission routes is parenteral, and in 30-40% of the cases is unknown (e.g. sexual route). Knowing these routes in HIV infected dyads is very important due to clinical and methodological reasons. Objectives: The present study aimed to identify and quantitatively investigate HIV-infected individuals and their main heterosexual partners regarding the risk factors of HCV transmission. Patients and Methods: One hundred sixty eight of 984 couples were chosen through random generated numbers using a computer program from behavioral consultation center in Shiraz, Iran. We used actor partner independent model (APIM) and multilevel analysis to assess multiple risk factors for HCV, while partitioning the source of risk at the individual and couple levels. Results: Age of the index samples was 38.71 ± 7 years, and 33.2 ± 6.3 for their main heterosexual partners; the mean duration of sexual relationship for couples was 11.9 (median = 8.5) years. Multivariate analysis showed that actor risk factor of intravenous drug using (IDU) (AOR= 13.03; 95% CI: 3.9-43.82) and actor cofactors of HIV positivity (AOR = 7.1; 95% CI: 1.37-36.97), razor sharing (AOR = 4.81; 95% CI: 1.84-12.55), sex (AOR = 8.83; 95% CI: 3.16-24.87), and condom use in sexual activity with main partner (AOR = 0.15; 95% CI: 0.02-0.44) were associated with actor HCV positivity. Conclusions: Health care providers need to pay special attention to sexual transmission of HCV among HIV-infected individuals, and should recommend control/preventive measures for HCV sexual transmission.
Iranian journal of public health, 2013
Cooperation of all health sectors and early diagnosis of the disease are the key factors for cont... more Cooperation of all health sectors and early diagnosis of the disease are the key factors for controlling tuberculosis. This study assesses the patterns of reported tuberculosis cases in Iran. This was a cross sectional study. Tuberculosis cases were defined according to World Health Organization and Iran's national TB guidelines. Final data were prepared for analysis using SPSS16 software. Public hospitals, public and private outpatient clinics reported 4111 (39.1%), 3007 (28.6%) and 2839 (27%) cases of TB, respectively. The highest number of reported TB cases was from the public healthcare system. One third of TB cases were reported by private outpatient clinics. It is essential to make a plan such as public-private mix model in Iran. Because of high coverage of private physicians in our country and even in rural areas, it is quite necessary to involve private system in tuberculosis program.
Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences, 2012
Early diagnosis of tuberculosis (TB) is a major key for effective TB program. Evaluation of delay... more Early diagnosis of tuberculosis (TB) is a major key for effective TB program. Evaluation of delay in diagnosis of smear positive TB is needed to evaluation of TB program situation in each country. The aim of this study was to evaluate of diagnosis delay in smear positive tuberculosis patients in Islamic Republic of Iran. In this cross sectional study, all smear positive TB registered patients from 20 March 2009 to 20 March 2010 in Iran were assessed. Diagnosis delay is defined as the time interval between the first presentations of TB symptoms to the TB confirmation. Mann-Whitney test, chi-square and logistic regression was used to analysis. Diagnosis delay was 58 days in female and 53 days in male (P=0.004), 61 days in non-Iranian and 54 days in Iranian (P<0.001), 59 days in urban and 50 days in rural (P<0.001), 57 days in non-prisoner and 37 days in prisoner (P<0.001), 61 days in patients who chose private outpatients system and 52 days in patients who chose Public health...
Uploads
Papers by Abbas Rezaianzadeh