Would it be possible to use systemd-inhibit command in wakepy?

Pros:

• Might allow more DEs to be supported. Many distros come with systemd, but not all implement the used D-Bus interfaces.

To consider:

• Wakepy methods should release the locks even if the process is killed abruptly. Check if this can be achieved.
• See the comment about systemd-inhibit here: List of deprecated and unsupported ways for inhibiting screensaver or suspend #319 (comment)