According to Wikipedia article, Lāmaḏ+ʾĀlap̄ (ʾEsṭrangēlā and Maḏnḥāyā), Taw+ʾĀlap̄ (ʾEsṭrangēlā and Maḏnḥāyā), Hē+Yōḏ (Maḏnḥāyā only), Taw+Yōḏ (Maḏnḥāyā only) has ligatures within Syriac texts, but some of them were incorrect in Noto Sans Syriac Estrangela and Noto Sans Syriac Estrangela Eastern.