It would be wonderful to have both read_sql() and to_sql(), analogous to pandas for those times when you have to clean up inconveniently large datasets. I saw http://stackoverflow.com/questions/33129839/choosing-a-framework-for-larger-than-memory-data-analysis-with-python but it appears that no issue had been opened yet