I'm using astropy 1.1.1 and Windows10 with python 3.5 (Anaconda installation). I always dismissed it in the past but everything that imports astropy takes very long on my computer:

%time import astropy
Wall time: 1.62 s
Wall time: 1.63 s
Wall time: 1.62 s
Wall time: 1.61 s
Wall time: 1.62 s
%time from astropy.nddata import NDData
Wall time: 7.05 s # fluke(?)
Wall time: 3.38 s
Wall time: 3.52 s
Wall time: 3.39 s

I'm not sure what is causing this and I don't know how one would profile something like this.