Pip allows a user to set configuration settings inside a pip.conf, usually stored at ~/.config/pip/pip.conf. For example, setting a default index-url. uv seems to ignore these settings completely.

This is a problem since enterprise companies typically have their own PyPI images and don't want users to use the public PyPI for security reasons. For example, users who use AWS codeartifact have this config file updated automatically when they run aws login. https://docs.aws.amazon.com/codeartifact/latest/ug/python-configure-pip.html