faers/README.html at a63eb58440b629dc369140876d13c87793435aa3 · WangLabCSU/faers

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<body>

<h1 id="faers-pharmacovigilance">FAERS-Pharmacovigilance</h1>

<ul>

<li><a href="#introduction">Introduction</a></li>

<li><a href="#installation">Installation</a></li>

<li><a href="#pharmacovigilance-analysis-using-faers">Pharmacovigilance

Analysis using FAERS</a>

<ul>

<li><a href="#check-metadata-of-faers">Check metadata of FAERS</a></li>

<li><a href="#download-and-parse-quarterly-data-files-from-faers">Download and

Parse quarterly data files from FAERS</a></li>

<li><a href="#standardize-and-de-duplication">Standardize and

De-duplication</a></li>

<li><a href="#pharmacovigilance-analysis">Pharmacovigilance

analysis</a></li>

</ul></li>

<li><a href="#sessioninfo">sessionInfo</a></li>

</ul>

<h2 id="introduction">Introduction</h2>

The FDA Adverse Event Reporting System (FAERS) stands as a database

dedicated to the monitoring of post-marketing drug safety and exercises

a notable influence over FDA safety guidance documents, including the

modification of drug labels. The quantity of cases stored within FAERS

has experienced an exponential surge due to the refinement of submission

techniques and adherence to standardized data protocols, making it a

pivotal asset for the realm of regulatory science. While FAERS has

predominantly focused on safety signal detection, the faers package acts

as the intermediary, seamlessly bridging the gap between the FAERS

database and the programming language R. Moreover, the faers package

provides a unified methodology for the seamless execution of

pharmacovigilance analysis, facilitating the integration of genetic

tools in R. With an ultimate ambition towards precision medicine, it

aspires to scrutinize the vast expanse of the human genome, revealing

drug pathways that may be intricately tied to potentially functional,

population-differentiated polymorphisms.

<h2 id="installation">Installation</h2>

To install from Bioconductor, use the following code:

<div class="sourceCode" id="cb1"><pre class="sourceCode r"><code class="sourceCode r"><a href="#cb1-1" tabindex="-1"></a>if (!requireNamespace("BiocManager", quietly = TRUE)) {

<a href="#cb1-2" tabindex="-1"></a> install.packages("BiocManager")

<a href="#cb1-3" tabindex="-1"></a>}

<a href="#cb1-4" tabindex="-1"></a>BiocManager::install("faers")</code></pre></div>

You can install the development version of <code>faers</code> from <a href="https://github.com/WangLabCSU/faers">GitHub</a> with:

<div class="sourceCode" id="cb2"><pre class="sourceCode r"><code class="sourceCode r"><a href="#cb2-1" tabindex="-1"></a>if (!requireNamespace("pak")) {

<a href="#cb2-2" tabindex="-1"></a> install.packages("pak",

<a href="#cb2-3" tabindex="-1"></a> repos = sprintf(

<a href="#cb2-4" tabindex="-1"></a> "https://r-lib.github.io/p/pak/devel/%s/%s/%s",

<a href="#cb2-5" tabindex="-1"></a> .Platform$pkgType, R.Version()$os, R.Version()$arch

<a href="#cb2-6" tabindex="-1"></a> )

<a href="#cb2-7" tabindex="-1"></a> )

<a href="#cb2-8" tabindex="-1"></a>}

<a href="#cb2-9" tabindex="-1"></a>pak::pkg_install("WangLabCSU/faers")</code></pre></div>

<h2 id="pharmacovigilance-analysis-using-faers">Pharmacovigilance

Analysis using FAERS</h2>

FAERS is a database for the spontaneous reporting of adverse events

and medication errors involving human drugs and therapeutic biological

products. This package accelarate the process of Pharmacovigilance

Analysis using FAERS.

<div class="sourceCode" id="cb3"><pre class="sourceCode r"><code class="sourceCode r"><a href="#cb3-1" tabindex="-1"></a>library(faers)</code></pre></div>

<h3 id="check-metadata-of-faers">Check metadata of FAERS</h3>

This will return a data.table reporting years, period, quarter, and

file urls and file sizes. By default, this will use the cached file in

<code>tools::R_user_dir("faers", "cache")</code>. If it doesn’t exist,

the internal will parse metadata in <a href="https://fis.fda.gov/extensions/FPD-QDE-FAERS/FPD-QDE-FAERS.html">https://fis.fda.gov/extensions/FPD-QDE-FAERS/FPD-QDE-FAERS.html</a>

<div class="sourceCode" id="cb4"><pre class="sourceCode r"><code class="sourceCode r"><a href="#cb4-1" tabindex="-1"></a>faers_meta()</code></pre></div>

An metadata copy was associated with the package, just set

<code>internal = TRUE</code>.

<div class="sourceCode" id="cb5"><pre class="sourceCode r"><code class="sourceCode r"><a href="#cb5-1" tabindex="-1"></a>faers_meta(internal = TRUE)

<a href="#cb5-2" tabindex="-1"></a>#> → Using internal FAERS metadata

<a href="#cb5-3" tabindex="-1"></a>#> Snapshot time: 2024-09-19 00:18:06.64623

<a href="#cb5-4" tabindex="-1"></a>#> year quarter period

<a href="#cb5-6" tabindex="-1"></a>#> 1: 2024 q2 April - June

<a href="#cb5-7" tabindex="-1"></a>#> 2: 2024 q1 January - March

<a href="#cb5-8" tabindex="-1"></a>#> 3: 2023 q4 October - December

<a href="#cb5-9" tabindex="-1"></a>#> 4: 2023 q3 July - September

<a href="#cb5-10" tabindex="-1"></a>#> 5: 2023 q2 April - June

<a href="#cb5-11" tabindex="-1"></a>#> 6: 2023 q1 January - March

<a href="#cb5-12" tabindex="-1"></a>#> 7: 2022 q4 October - December

<a href="#cb5-13" tabindex="-1"></a>#> 8: 2022 q3 July - September

<a href="#cb5-14" tabindex="-1"></a>#> 9: 2022 q2 April - June

<a href="#cb5-15" tabindex="-1"></a>#> 10: 2022 q1 January - March

<a href="#cb5-16" tabindex="-1"></a>#> 11: 2021 q4 October - December

<a href="#cb5-17" tabindex="-1"></a>#> 12: 2021 q3 July - September

<a href="#cb5-18" tabindex="-1"></a>#> 13: 2021 q2 April - June

<a href="#cb5-19" tabindex="-1"></a>#> 14: 2021 q1 January - March

<a href="#cb5-20" tabindex="-1"></a>#> 15: 2020 q4 October - December

<a href="#cb5-21" tabindex="-1"></a>#> 16: 2020 q3 July - September

<a href="#cb5-22" tabindex="-1"></a>#> 17: 2020 q2 April - June

<a href="#cb5-23" tabindex="-1"></a>#> 18: 2020 q1 January - March

<a href="#cb5-24" tabindex="-1"></a>#> 19: 2019 q4 October - December

<a href="#cb5-25" tabindex="-1"></a>#> 20: 2019 q3 July - September

<a href="#cb5-26" tabindex="-1"></a>#> 21: 2019 q2 April - June

<a href="#cb5-27" tabindex="-1"></a>#> 22: 2019 q1 January - March

<a href="#cb5-28" tabindex="-1"></a>#> 23: 2018 q4 October - December

<a href="#cb5-29" tabindex="-1"></a>#> 24: 2018 q3 July - September

<a href="#cb5-30" tabindex="-1"></a>#> 25: 2018 q2 April - June

<a href="#cb5-31" tabindex="-1"></a>#> 26: 2018 q1 January - March

<a href="#cb5-32" tabindex="-1"></a>#> 27: 2017 q4 October - December

<a href="#cb5-33" tabindex="-1"></a>#> 28: 2017 q3 July - September

<a href="#cb5-34" tabindex="-1"></a>#> 29: 2017 q2 April - June

<a href="#cb5-35" tabindex="-1"></a>#> 30: 2017 q1 January - March

<a href="#cb5-36" tabindex="-1"></a>#> 31: 2016 q4 October - December

<a href="#cb5-37" tabindex="-1"></a>#> 32: 2016 q3 July - September

<a href="#cb5-38" tabindex="-1"></a>#> 33: 2016 q2 April - June

<a href="#cb5-39" tabindex="-1"></a>#> 34: 2016 q1 January - March

<a href="#cb5-40" tabindex="-1"></a>#> 35: 2015 q4 October - December

<a href="#cb5-41" tabindex="-1"></a>#> 36: 2015 q3 July - September

<a href="#cb5-42" tabindex="-1"></a>#> 37: 2015 q2 April - June

<a href="#cb5-43" tabindex="-1"></a>#> 38: 2015 q1 January - March

<a href="#cb5-44" tabindex="-1"></a>#> 39: 2014 q4 October - December

<a href="#cb5-45" tabindex="-1"></a>#> 40: 2014 q3 July - September

<a href="#cb5-46" tabindex="-1"></a>#> 41: 2014 q2 April - June

<a href="#cb5-47" tabindex="-1"></a>#> 42: 2014 q1 January - March

<a href="#cb5-48" tabindex="-1"></a>#> 43: 2013 q4 October - December

<a href="#cb5-49" tabindex="-1"></a>#> 44: 2013 q3 July - September

<a href="#cb5-50" tabindex="-1"></a>#> 45: 2013 q2 April - June

<a href="#cb5-51" tabindex="-1"></a>#> 46: 2013 q1 January - March

<a href="#cb5-52" tabindex="-1"></a>#> 47: 2012 q4 October - December

<a href="#cb5-53" tabindex="-1"></a>#> 48: 2012 q3 July - September

<a href="#cb5-54" tabindex="-1"></a>#> 49: 2012 q2 April - June

<a href="#cb5-55" tabindex="-1"></a>#> 50: 2012 q1 January - March

<a href="#cb5-56" tabindex="-1"></a>#> 51: 2011 q4 October - December

<a href="#cb5-57" tabindex="-1"></a>#> 52: 2011 q3 July - September

<a href="#cb5-58" tabindex="-1"></a>#> 53: 2011 q2 April - June

<a href="#cb5-59" tabindex="-1"></a>#> 54: 2011 q1 January - March

<a href="#cb5-60" tabindex="-1"></a>#> 55: 2010 q4 October - December

<a href="#cb5-61" tabindex="-1"></a>#> 56: 2010 q3 July - September

<a href="#cb5-62" tabindex="-1"></a>#> 57: 2010 q2 April - June

<a href="#cb5-63" tabindex="-1"></a>#> 58: 2010 q1 January - March

<a href="#cb5-64" tabindex="-1"></a>#> 59: 2009 q4 October - December

<a href="#cb5-65" tabindex="-1"></a>#> 60: 2009 q3 July - September

<a href="#cb5-66" tabindex="-1"></a>#> 61: 2009 q2 April - June

<a href="#cb5-67" tabindex="-1"></a>#> 62: 2009 q1 January - March

<a href="#cb5-68" tabindex="-1"></a>#> 63: 2008 q4 October - December

<a href="#cb5-69" tabindex="-1"></a>#> 64: 2008 q3 July - September

<a href="#cb5-70" tabindex="-1"></a>#> 65: 2008 q2 April - June

<a href="#cb5-71" tabindex="-1"></a>#> 66: 2008 q1 January - March

<a href="#cb5-72" tabindex="-1"></a>#> 67: 2007 q4 October - December

<a href="#cb5-73" tabindex="-1"></a>#> 68: 2007 q3 July - September

<a href="#cb5-74" tabindex="-1"></a>#> 69: 2007 q2 April - June

<a href="#cb5-75" tabindex="-1"></a>#> 70: 2007 q1 January - March

<a href="#cb5-76" tabindex="-1"></a>#> ascii_urls ascii_file_size

<a href="#cb5-78" tabindex="-1"></a>#> 1: https://fis.fda.gov/content/Exports/faers_ascii_2024q2.zip 63.9MB

<a href="#cb5-79" tabindex="-1"></a>#> 2: https://fis.fda.gov/content/Exports/faers_ascii_2024q1.zip 63.1MB

<a href="#cb5-80" tabindex="-1"></a>#> 3: https://fis.fda.gov/content/Exports/faers_ascii_2023Q4.zip 69.1MB

<a href="#cb5-81" tabindex="-1"></a>#> 4: https://fis.fda.gov/content/Exports/faers_ascii_2023Q3.zip 60.1MB

<a href="#cb5-82" tabindex="-1"></a>#> 5: https://fis.fda.gov/content/Exports/faers_ascii_2023q2.zip 64.5MB

<a href="#cb5-83" tabindex="-1"></a>#> 6: https://fis.fda.gov/content/Exports/faers_ascii_2023q1.zip 64.3MB

<a href="#cb5-84" tabindex="-1"></a>#> 7: https://fis.fda.gov/content/Exports/faers_ascii_2022Q4.zip 69MB

<a href="#cb5-85" tabindex="-1"></a>#> 8: https://fis.fda.gov/content/Exports/faers_ascii_2022Q3.zip 63.2MB

<a href="#cb5-86" tabindex="-1"></a>#> 9: https://fis.fda.gov/content/Exports/faers_ascii_2022q2.zip 63MB

<a href="#cb5-87" tabindex="-1"></a>#> 10: https://fis.fda.gov/content/Exports/faers_ascii_2022q1.zip 64.7MB

<a href="#cb5-88" tabindex="-1"></a>#> 11: https://fis.fda.gov/content/Exports/faers_ascii_2021Q4.zip 59MB

<a href="#cb5-89" tabindex="-1"></a>#> 12: https://fis.fda.gov/content/Exports/faers_ascii_2021Q3.zip 70MB

<a href="#cb5-90" tabindex="-1"></a>#> 13: https://fis.fda.gov/content/Exports/faers_ascii_2021Q2.zip 66MB

<a href="#cb5-91" tabindex="-1"></a>#> 14: https://fis.fda.gov/content/Exports/faers_ascii_2021Q1.zip 69MB

<a href="#cb5-92" tabindex="-1"></a>#> 15: https://fis.fda.gov/content/Exports/faers_ascii_2020Q4.zip 71MB

<a href="#cb5-93" tabindex="-1"></a>#> 16: https://fis.fda.gov/content/Exports/faers_ascii_2020Q3.zip 64MB

<a href="#cb5-94" tabindex="-1"></a>#> 17: https://fis.fda.gov/content/Exports/faers_ascii_2020Q2.zip 66MB

<a href="#cb5-95" tabindex="-1"></a>#> 18: https://fis.fda.gov/content/Exports/faers_ascii_2020Q1.zip 65MB

<a href="#cb5-96" tabindex="-1"></a>#> 19: https://fis.fda.gov/content/Exports/faers_ascii_2019Q4.zip 60MB

<a href="#cb5-97" tabindex="-1"></a>#> 20: https://fis.fda.gov/content/Exports/faers_ascii_2019Q3.zip 62MB

<a href="#cb5-98" tabindex="-1"></a>#> 21: https://fis.fda.gov/content/Exports/faers_ascii_2019Q2.zip 62MB

<a href="#cb5-99" tabindex="-1"></a>#> 22: https://fis.fda.gov/content/Exports/faers_ascii_2019Q1.zip 56MB

<a href="#cb5-100" tabindex="-1"></a>#> 23: https://fis.fda.gov/content/Exports/faers_ascii_2018q4.zip 60MB

<a href="#cb5-101" tabindex="-1"></a>#> 24: https://fis.fda.gov/content/Exports/faers_ascii_2018q3.zip 60MB

<a href="#cb5-102" tabindex="-1"></a>#> 25: https://fis.fda.gov/content/Exports/faers_ascii_2018q2.zip 60MB

<a href="#cb5-103" tabindex="-1"></a>#> 26: https://fis.fda.gov/content/Exports/faers_ascii_2018q1.zip 52MB

<a href="#cb5-104" tabindex="-1"></a>#> 27: https://fis.fda.gov/content/Exports/faers_ascii_2017q4.zip 41MB

<a href="#cb5-105" tabindex="-1"></a>#> 28: https://fis.fda.gov/content/Exports/faers_ascii_2017q3.zip 48MB

<a href="#cb5-106" tabindex="-1"></a>#> 29: https://fis.fda.gov/content/Exports/faers_ascii_2017q2.zip 46MB

<a href="#cb5-107" tabindex="-1"></a>#> 30: https://fis.fda.gov/content/Exports/faers_ascii_2017q1.zip 48MB

<a href="#cb5-108" tabindex="-1"></a>#> 31: https://fis.fda.gov/content/Exports/faers_ascii_2016q4.zip 44MB

<a href="#cb5-109" tabindex="-1"></a>#> 32: https://fis.fda.gov/content/Exports/faers_ascii_2016q3.zip 46MB

<a href="#cb5-110" tabindex="-1"></a>#> 33: https://fis.fda.gov/content/Exports/faers_ascii_2016q2.zip 44MB

<a href="#cb5-111" tabindex="-1"></a>#> 34: https://fis.fda.gov/content/Exports/faers_ascii_2016q1.zip 46MB

<a href="#cb5-112" tabindex="-1"></a>#> 35: https://fis.fda.gov/content/Exports/faers_ascii_2015q4.zip 42MB

<a href="#cb5-113" tabindex="-1"></a>#> 36: https://fis.fda.gov/content/Exports/faers_ascii_2015q3.zip 47MB

<a href="#cb5-114" tabindex="-1"></a>#> 37: https://fis.fda.gov/content/Exports/faers_ascii_2015q2.zip 38MB

<a href="#cb5-115" tabindex="-1"></a>#> 38: https://fis.fda.gov/content/Exports/faers_ascii_2015q1.zip 39MB

<a href="#cb5-116" tabindex="-1"></a>#> 39: https://fis.fda.gov/content/Exports/faers_ascii_2014q4.zip 28MB

<a href="#cb5-117" tabindex="-1"></a>#> 40: https://fis.fda.gov/content/Exports/faers_ascii_2014q3.zip 28MB

<a href="#cb5-118" tabindex="-1"></a>#> 41: https://fis.fda.gov/content/Exports/faers_ascii_2014q2.zip 25MB

<a href="#cb5-119" tabindex="-1"></a>#> 42: https://fis.fda.gov/content/Exports/faers_ascii_2014q1.zip 30MB

<a href="#cb5-120" tabindex="-1"></a>#> 43: https://fis.fda.gov/content/Exports/faers_ascii_2013q4.zip 26MB

<a href="#cb5-121" tabindex="-1"></a>#> 44: https://fis.fda.gov/content/Exports/faers_ascii_2013q3.zip 22MB

<a href="#cb5-122" tabindex="-1"></a>#> 45: https://fis.fda.gov/content/Exports/faers_ascii_2013q2.zip 21MB

<a href="#cb5-123" tabindex="-1"></a>#> 46: https://fis.fda.gov/content/Exports/faers_ascii_2013q1.zip 25MB

<a href="#cb5-124" tabindex="-1"></a>#> 47: https://fis.fda.gov/content/Exports/faers_ascii_2012q4.zip 28MB

<a href="#cb5-125" tabindex="-1"></a>#> 48: https://fis.fda.gov/content/Exports/aers_ascii_2012q3.zip 16MB

<a href="#cb5-126" tabindex="-1"></a>#> 49: https://fis.fda.gov/content/Exports/aers_ascii_2012q2.zip 25MB

<a href="#cb5-127" tabindex="-1"></a>#> 50: https://fis.fda.gov/content/Exports/aers_ascii_2012q1.zip 26MB

<a href="#cb5-128" tabindex="-1"></a>#> 51: https://fis.fda.gov/content/Exports/aers_ascii_2011q4.zip 23MB

<a href="#cb5-129" tabindex="-1"></a>#> 52: https://fis.fda.gov/content/Exports/aers_ascii_2011q3.zip 23MB

<a href="#cb5-130" tabindex="-1"></a>#> 53: https://fis.fda.gov/content/Exports/aers_ascii_2011q2.zip 23MB

<a href="#cb5-131" tabindex="-1"></a>#> 54: https://fis.fda.gov/content/Exports/aers_ascii_2011q1.zip 21MB

<a href="#cb5-132" tabindex="-1"></a>#> 55: https://fis.fda.gov/content/Exports/aers_ascii_2010q4.zip 20MB

<a href="#cb5-133" tabindex="-1"></a>#> 56: https://fis.fda.gov/content/Exports/aers_ascii_2010q3.zip 22MB

<a href="#cb5-134" tabindex="-1"></a>#> 57: https://fis.fda.gov/content/Exports/aers_ascii_2010q2.zip 17MB

<a href="#cb5-135" tabindex="-1"></a>#> 58: https://fis.fda.gov/content/Exports/aers_ascii_2010q1.zip 16MB

<a href="#cb5-136" tabindex="-1"></a>#> 59: https://fis.fda.gov/content/Exports/aers_ascii_2009q4.zip 16MB

<a href="#cb5-137" tabindex="-1"></a>#> 60: https://fis.fda.gov/content/Exports/aers_ascii_2009q3.zip 16MB

<a href="#cb5-138" tabindex="-1"></a>#> 61: https://fis.fda.gov/content/Exports/aers_ascii_2009q2.zip 14MB

<a href="#cb5-139" tabindex="-1"></a>#> 62: https://fis.fda.gov/content/Exports/aers_ascii_2009q1.zip 13MB

<a href="#cb5-140" tabindex="-1"></a>#> 63: https://fis.fda.gov/content/Exports/aers_ascii_2008q4.zip 13MB

<a href="#cb5-141" tabindex="-1"></a>#> 64: https://fis.fda.gov/content/Exports/aers_ascii_2008q3.zip 13MB

<a href="#cb5-142" tabindex="-1"></a>#> 65: https://fis.fda.gov/content/Exports/aers_ascii_2008q2.zip 12MB

<a href="#cb5-143" tabindex="-1"></a>#> 66: https://fis.fda.gov/content/Exports/aers_ascii_2008q1.zip 12MB

<a href="#cb5-144" tabindex="-1"></a>#> 67: https://fis.fda.gov/content/Exports/aers_ascii_2007q4.zip 12MB

<a href="#cb5-145" tabindex="-1"></a>#> 68: https://fis.fda.gov/content/Exports/aers_ascii_2007q3.zip 9.9MB

<a href="#cb5-146" tabindex="-1"></a>#> 69: https://fis.fda.gov/content/Exports/aers_ascii_2007q2.zip 9.5MB

<a href="#cb5-147" tabindex="-1"></a>#> 70: https://fis.fda.gov/content/Exports/aers_ascii_2007q1.zip 9.6MB

<a href="#cb5-148" tabindex="-1"></a>#> xml_urls xml_file_size

<a href="#cb5-150" tabindex="-1"></a>#> 1: https://fis.fda.gov/content/Exports/faers_xml_2024q2.zip 126MB

<a href="#cb5-151" tabindex="-1"></a>#> 2: https://fis.fda.gov/content/Exports/faers_xml_2024q1.zip 128MB

<a href="#cb5-152" tabindex="-1"></a>#> 3: https://fis.fda.gov/content/Exports/faers_xml_2023Q4.zip 140MB

<a href="#cb5-153" tabindex="-1"></a>#> 4: https://fis.fda.gov/content/Exports/faers_xml_2023Q3.zip 123MB

<a href="#cb5-154" tabindex="-1"></a>#> 5: https://fis.fda.gov/content/Exports/faers_xml_2023q2.zip 130MB

<a href="#cb5-155" tabindex="-1"></a>#> 6: https://fis.fda.gov/content/Exports/faers_xml_2023q1.zip 133MB

<a href="#cb5-156" tabindex="-1"></a>#> 7: https://fis.fda.gov/content/Exports/faers_xml_2022Q4.zip 144MB

<a href="#cb5-157" tabindex="-1"></a>#> 8: https://fis.fda.gov/content/Exports/faers_xml_2022Q3.zip 132MB

<a href="#cb5-158" tabindex="-1"></a>#> 9: https://fis.fda.gov/content/Exports/faers_xml_2022q2.zip 140MB

<a href="#cb5-159" tabindex="-1"></a>#> 10: https://fis.fda.gov/content/Exports/faers_xml_2022q1.zip 136MB

<a href="#cb5-160" tabindex="-1"></a>#> 11: https://fis.fda.gov/content/Exports/faers_xml_2021Q4.zip 123MB

<a href="#cb5-161" tabindex="-1"></a>#> 12: https://fis.fda.gov/content/Exports/faers_xml_2021Q3.zip 132MB

<a href="#cb5-162" tabindex="-1"></a>#> 13: https://fis.fda.gov/content/Exports/faers_xml_2021Q2.zip 123MB

<a href="#cb5-163" tabindex="-1"></a>#> 14: https://fis.fda.gov/content/Exports/faers_xml_2021Q1.zip 130MB

<a href="#cb5-164" tabindex="-1"></a>#> 15: https://fis.fda.gov/content/Exports/faers_xml_2020Q4.zip 131MB

<a href="#cb5-165" tabindex="-1"></a>#> 16: https://fis.fda.gov/content/Exports/faers_xml_2020Q3.zip 121MB

<a href="#cb5-166" tabindex="-1"></a>#> 17: https://fis.fda.gov/content/Exports/faers_xml_2020Q2.zip 123MB

<a href="#cb5-167" tabindex="-1"></a>#> 18: https://fis.fda.gov/content/Exports/faers_xml_2020Q1.zip 125MB

<a href="#cb5-168" tabindex="-1"></a>#> 19: https://fis.fda.gov/content/Exports/faers_xml_2019Q4.zip 113MB

<a href="#cb5-169" tabindex="-1"></a>#> 20: https://fis.fda.gov/content/Exports/faers_xml_2019Q3.zip 118MB

<a href="#cb5-170" tabindex="-1"></a>#> 21: https://fis.fda.gov/content/Exports/faers_xml_2019Q2.zip 118MB

<a href="#cb5-171" tabindex="-1"></a>#> 22: https://fis.fda.gov/content/Exports/faers_xml_2019Q1.zip 103MB

<a href="#cb5-172" tabindex="-1"></a>#> 23: https://fis.fda.gov/content/Exports/faers_xml_2018q4.zip 112MB

<a href="#cb5-173" tabindex="-1"></a>#> 24: https://fis.fda.gov/content/Exports/faers_xml_2018q3.zip 112MB

<a href="#cb5-174" tabindex="-1"></a>#> 25: https://fis.fda.gov/content/Exports/faers_xml_2018q2.zip 112MB

<a href="#cb5-175" tabindex="-1"></a>#> 26: https://fis.fda.gov/content/Exports/faers_xml_2018q1.zip 94MB

<a href="#cb5-176" tabindex="-1"></a>#> 27: https://fis.fda.gov/content/Exports/faers_xml_2017q4.zip 76MB

<a href="#cb5-177" tabindex="-1"></a>#> 28: https://fis.fda.gov/content/Exports/faers_xml_2017q3.zip 91MB

<a href="#cb5-178" tabindex="-1"></a>#> 29: https://fis.fda.gov/content/Exports/faers_xml_2017q2.zip 86MB

<a href="#cb5-179" tabindex="-1"></a>#> 30: https://fis.fda.gov/content/Exports/faers_xml_2017q1.zip 91MB

<a href="#cb5-180" tabindex="-1"></a>#> 31: https://fis.fda.gov/content/Exports/faers_xml_2016q4.zip 82MB

<a href="#cb5-181" tabindex="-1"></a>#> 32: https://fis.fda.gov/content/Exports/faers_xml_2016q3.zip 87MB

<a href="#cb5-182" tabindex="-1"></a>#> 33: https://fis.fda.gov/content/Exports/faers_xml_2016q2.zip 81MB

<a href="#cb5-183" tabindex="-1"></a>#> 34: https://fis.fda.gov/content/Exports/faers_xml_2016q1.zip 84MB

<a href="#cb5-184" tabindex="-1"></a>#> 35: https://fis.fda.gov/content/Exports/faers_xml_2015q4.zip 77MB

<a href="#cb5-185" tabindex="-1"></a>#> 36: https://fis.fda.gov/content/Exports/faers_xml_2015q3.zip 88MB

<a href="#cb5-186" tabindex="-1"></a>#> 37: https://fis.fda.gov/content/Exports/faers_xml_2015q2.zip 70MB

<a href="#cb5-187" tabindex="-1"></a>#> 38: https://fis.fda.gov/content/Exports/faers_xml_2015q1.zip 72MB

<a href="#cb5-188" tabindex="-1"></a>#> 39: https://fis.fda.gov/content/Exports/faers_xml_2014q4.zip 53MB

<a href="#cb5-189" tabindex="-1"></a>#> 40: https://fis.fda.gov/content/Exports/faers_xml_2014q3.zip 54MB

<a href="#cb5-190" tabindex="-1"></a>#> 41: https://fis.fda.gov/content/Exports/faers_xml_2014q2.zip 44MB

<a href="#cb5-191" tabindex="-1"></a>#> 42: https://fis.fda.gov/content/Exports/faers_xml_2014q1.zip 52MB

<a href="#cb5-192" tabindex="-1"></a>#> 43: https://fis.fda.gov/content/Exports/faers_xml_2013q4.zip 46MB

<a href="#cb5-193" tabindex="-1"></a>#> 44: https://fis.fda.gov/content/Exports/faers_xml_2013q3.zip 40MB

<a href="#cb5-194" tabindex="-1"></a>#> 45: https://fis.fda.gov/content/Exports/faers_xml_2013q2.zip 38MB

<a href="#cb5-195" tabindex="-1"></a>#> 46: https://fis.fda.gov/content/Exports/faers_xml_2013q1.zip 44MB

<a href="#cb5-196" tabindex="-1"></a>#> 47: https://fis.fda.gov/content/Exports/faers_xml_2012q4.zip 50MB

<a href="#cb5-197" tabindex="-1"></a>#> 48: https://fis.fda.gov/content/Exports/aers_sgml_2012q3.zip 21MB

<a href="#cb5-198" tabindex="-1"></a>#> 49: https://fis.fda.gov/content/Exports/aers_sgml_2012q2.zip 32MB

<a href="#cb5-199" tabindex="-1"></a>#> 50: https://fis.fda.gov/content/Exports/aers_sgml_2012q1.zip 33MB

<a href="#cb5-200" tabindex="-1"></a>#> 51: https://fis.fda.gov/content/Exports/aers_sgml_2011q4.zip 29MB

<a href="#cb5-201" tabindex="-1"></a>#> 52: https://fis.fda.gov/content/Exports/aers_sgml_2011q3.zip 29MB

<a href="#cb5-202" tabindex="-1"></a>#> 53: https://fis.fda.gov/content/Exports/aers_sgml_2011q2.zip 29MB

<a href="#cb5-203" tabindex="-1"></a>#> 54: https://fis.fda.gov/content/Exports/aers_sgml_2011q1.zip 26MB

<a href="#cb5-204" tabindex="-1"></a>#> 55: https://fis.fda.gov/content/Exports/aers_sgml_2010q4.zip 25MB

<a href="#cb5-205" tabindex="-1"></a>#> 56: https://fis.fda.gov/content/Exports/aers_sgml_2010q3.zip 28MB

<a href="#cb5-206" tabindex="-1"></a>#> 57: https://fis.fda.gov/content/Exports/aers_sgml_2010q2.zip 22MB

<a href="#cb5-207" tabindex="-1"></a>#> 58: https://fis.fda.gov/content/Exports/aers_sgml_2010q1.zip 20MB

<a href="#cb5-208" tabindex="-1"></a>#> 59: https://fis.fda.gov/content/Exports/aers_sgml_2009q4.zip 20MB

<a href="#cb5-209" tabindex="-1"></a>#> 60: https://fis.fda.gov/content/Exports/aers_sgml_2009q3.zip 19MB

<a href="#cb5-210" tabindex="-1"></a>#> 61: https://fis.fda.gov/content/Exports/aers_sgml_2009q2.zip 18MB

<a href="#cb5-211" tabindex="-1"></a>#> 62: https://fis.fda.gov/content/Exports/aers_sgml_2009q1.zip 16MB

<a href="#cb5-212" tabindex="-1"></a>#> 63: https://fis.fda.gov/content/Exports/aers_sgml_2008q4.zip 16MB

<a href="#cb5-213" tabindex="-1"></a>#> 64: https://fis.fda.gov/content/Exports/aers_sgml_2008q3.zip 16MB

<a href="#cb5-214" tabindex="-1"></a>#> 65: https://fis.fda.gov/content/Exports/aers_sgml_2008q2.zip 16MB

<a href="#cb5-215" tabindex="-1"></a>#> 66: https://fis.fda.gov/content/Exports/aers_sgml_2008q1.zip 15MB

<a href="#cb5-216" tabindex="-1"></a>#> 67: https://fis.fda.gov/content/Exports/aers_sgml_2007q4.zip 14MB

<a href="#cb5-217" tabindex="-1"></a>#> 68: https://fis.fda.gov/content/Exports/aers_sgml_2007q3.zip 13MB

<a href="#cb5-218" tabindex="-1"></a>#> 69: https://fis.fda.gov/content/Exports/aers_sgml_2007q2.zip 12MB

<a href="#cb5-219" tabindex="-1"></a>#> 70: https://fis.fda.gov/content/Exports/aers_sgml_2007q1.zip 12MB

<a href="#cb5-220" tabindex="-1"></a>#> [ reached getOption("max.print") -- omitted 13 rows ]</code></pre></div>

<h3 id="download-and-parse-quarterly-data-files-from-faers">Download and

Parse quarterly data files from FAERS</h3>

The FAERS Quarterly Data files contain raw data extracted from the

AERS database for the indicated time ranges. The quarterly data files,

which are available in ASCII or SGML formats, include:

<ul>

<li><code>demo</code>: demographic and administrative information</li>

<li><code>drug</code>: drug information from the case reports</li>

<li><code>reac</code>: reaction information from the reports</li>

<li><code>outc</code>: patient outcome information from the reports</li>

<li><code>rpsr</code>: information on the source of the reports</li>

<li><code>ther</code>: drug therapy start dates and end dates for the

reported drugs</li>

<li><code>indi</code>: contains all “Medical Dictionary for Regulatory

Activities” (MedDRA) terms coded for the indications for use (diagnoses)

for the reported drugs</li>

</ul>

Generally, we can use <code>faers()</code> function to download and

parse all quarterly data files from FAERS. Internally, the

<code>faers()</code> function seamlessly utilizes

<code>faers_download()</code> and <code>faers_parse()</code> to

preprocess each quarterly data file from the FAERS repository. The

default <code>format</code> was <code>ascii</code> and will return a

<code>FAERSascii</code> object. (xml format would also be okay , but

presently, the XML file receives only minimal support in the following

process.)

Some variables has been added into specific field. See

<code>?faers_parse</code> for details.

<div class="sourceCode" id="cb6"><pre class="sourceCode r"><code class="sourceCode r"><a href="#cb6-1" tabindex="-1"></a># Please make sure to replace dir with your own directory path, as the file

<a href="#cb6-2" tabindex="-1"></a># included in the package is a sampled version.

<a href="#cb6-3" tabindex="-1"></a>data1 <- faers(2004, "q1",

<a href="#cb6-4" tabindex="-1"></a> dir = system.file("extdata", package = "faers"),

<a href="#cb6-5" tabindex="-1"></a> compress_dir = tempdir()

<a href="#cb6-6" tabindex="-1"></a>)

<a href="#cb6-7" tabindex="-1"></a>#> Finding 1 file already downloaded: 'aers_ascii_2004q1.zip'

<a href="#cb6-8" tabindex="-1"></a>data1

<a href="#cb6-9" tabindex="-1"></a>#> FAERS data from 1 Quarterly ascii file

<a href="#cb6-10" tabindex="-1"></a>#> Total reports: 100 (with duplicates)</code></pre></div>

Furthermore, in cases where multiple quarterly data files are

requisite, the <code>faers_combine()</code> function is judiciously

employed.

<div class="sourceCode" id="cb7"><pre class="sourceCode r"><code class="sourceCode r"><a href="#cb7-1" tabindex="-1"></a>data2 <- faers(c(2004, 2017), c("q1", "q2"),

<a href="#cb7-2" tabindex="-1"></a> dir = system.file("extdata", package = "faers"),

<a href="#cb7-3" tabindex="-1"></a> compress_dir = tempdir()

<a href="#cb7-4" tabindex="-1"></a>)

<a href="#cb7-5" tabindex="-1"></a>#> Finding 2 files already downloaded: 'aers_ascii_2004q1.zip' and

<a href="#cb7-6" tabindex="-1"></a>#> 'faers_ascii_2017q2.zip'

<a href="#cb7-7" tabindex="-1"></a>#> → Combining all 2 <FAERS> Datas

<a href="#cb7-8" tabindex="-1"></a>data2

<a href="#cb7-9" tabindex="-1"></a>#> FAERS data from 2 Quarterly ascii files

<a href="#cb7-10" tabindex="-1"></a>#> Total reports: 200 (with duplicates)</code></pre></div>

You can use <code>faers_get()</code> to get specific field data, a

data.table will be returned.

<div class="sourceCode" id="cb8"><pre class="sourceCode r"><code class="sourceCode r"><a href="#cb8-1" tabindex="-1"></a>faers_get(data2, "demo")

<a href="#cb8-2" tabindex="-1"></a>#> year quarter primaryid caseid i_f_code foll_seq image event_dt

<a href="#cb8-4" tabindex="-1"></a>#> 1: 2004 q1 4263764 4060920 I NA 4263764-6 20020101

<a href="#cb8-5" tabindex="-1"></a>#> 2: 2004 q1 4263927 4064250 I NA 4263927-X NA

<a href="#cb8-6" tabindex="-1"></a>#> 3: 2004 q1 4264001 4062524 I NA 4264001-9 20031218

<a href="#cb8-7" tabindex="-1"></a>#> 4: 2004 q1 4264319 4064506 I NA 4264319-X 20031216

<a href="#cb8-8" tabindex="-1"></a>#> 5: 2004 q1 4266745 4056689 I NA 4266745-1 20030529

<a href="#cb8-9" tabindex="-1"></a>#> ---

<a href="#cb8-10" tabindex="-1"></a>#> 196: 2017 q2 136874291 13687429 I NA <NA> NA

<a href="#cb8-11" tabindex="-1"></a>#> 197: 2017 q2 136987441 13698744 I NA <NA> 201706

<a href="#cb8-12" tabindex="-1"></a>#> 198: 2017 q2 137054551 13705455 I NA <NA> 20160103

<a href="#cb8-13" tabindex="-1"></a>#> 199: 2017 q2 137055661 13705566 I NA <NA> NA

<a href="#cb8-14" tabindex="-1"></a>#> 200: 2017 q2 137086221 13708622 I NA <NA> NA

<a href="#cb8-15" tabindex="-1"></a>#> mfr_dt fda_dt rept_cod mfr_num

<a href="#cb8-17" tabindex="-1"></a>#> 1: 20031219 20040102 EXP USA031255171

<a href="#cb8-18" tabindex="-1"></a>#> 2: 20031209 20040102 EXP B0317710A

<a href="#cb8-19" tabindex="-1"></a>#> 3: 20031219 20040102 EXP JP-JNJFOC-20031204393

<a href="#cb8-20" tabindex="-1"></a>#> 4: 20031218 20040105 EXP MEDI-0001221

<a href="#cb8-21" tabindex="-1"></a>#> 5: 20040105 20040108 EXP FR-GLAXOSMITHKLINE-B0318977A

<a href="#cb8-22" tabindex="-1"></a>#> ---

<a href="#cb8-23" tabindex="-1"></a>#> 196: 20170612 20170624 EXP GB-TORRENT-00015363

<a href="#cb8-24" tabindex="-1"></a>#> 197: 20170623 20170628 EXP JP-PFIZER INC-2017277430

<a href="#cb8-25" tabindex="-1"></a>#> 198: 20170501 20170630 EXP US-BAYER-2017-084170

<a href="#cb8-26" tabindex="-1"></a>#> 199: 20140423 20170630 PER US-IPSEN BIOPHARMACEUTICALS, INC.-2014-2195

<a href="#cb8-27" tabindex="-1"></a>#> 200: 20151116 20170630 PER US-IPSEN BIOPHARMACEUTICALS, INC.-2015-08780

<a href="#cb8-28" tabindex="-1"></a>#> mfr_sndr age age_cod gender e_sub wt

<a href="#cb8-30" tabindex="-1"></a>#> 1: ELI LILLY AND COMPANY 68 YR F N 82.0

<a href="#cb8-31" tabindex="-1"></a>#> 2: GLAXOSMITHKLINE GLOBAL CLINICAL SAFETY 58 YR F N NA

<a href="#cb8-32" tabindex="-1"></a>#> 3: CENTOCOR, INC. 53 YR F N 36.8

<a href="#cb8-33" tabindex="-1"></a>#> 4: MEDIMUNE, INC. NA <NA> F N NA

<a href="#cb8-34" tabindex="-1"></a>#> 5: GLAXOSMITHKLINE 48 YR F Y NA

<a href="#cb8-35" tabindex="-1"></a>#> ---

<a href="#cb8-36" tabindex="-1"></a>#> 196: TORRENT NA <NA> <NA> Y NA

<a href="#cb8-37" tabindex="-1"></a>#> 197: PFIZER NA <NA> <NA> Y NA

<a href="#cb8-38" tabindex="-1"></a>#> 198: BAYER 84 YR M Y NA

<a href="#cb8-39" tabindex="-1"></a>#> 199: IPSEN NA <NA> F Y NA

<a href="#cb8-40" tabindex="-1"></a>#> 200: IPSEN 52 YR F Y NA

<a href="#cb8-41" tabindex="-1"></a>#> wt_cod rept_dt occp_cod death_dt to_mfr confid v23 caseversion

<a href="#cb8-43" tabindex="-1"></a>#> 1: KG 20031223 <NA> NA <NA> <NA> NA 0

<a href="#cb8-44" tabindex="-1"></a>#> 2: <NA> 20031219 <NA> NA <NA> <NA> NA 0

<a href="#cb8-45" tabindex="-1"></a>#> 3: KG 20031231 MD NA <NA> <NA> NA 0

<a href="#cb8-46" tabindex="-1"></a>#> 4: <NA> 20031231 MD NA <NA> <NA> NA 0

<a href="#cb8-47" tabindex="-1"></a>#> 5: <NA> 20040108 CN NA <NA> <NA> NA 0

<a href="#cb8-48" tabindex="-1"></a>#> ---

<a href="#cb8-49" tabindex="-1"></a>#> 196: <NA> 20170624 CN NA <NA> <NA> NA 1

<a href="#cb8-50" tabindex="-1"></a>#> 197: <NA> 20170628 MD NA <NA> <NA> NA 1

<a href="#cb8-51" tabindex="-1"></a>#> 198: <NA> 20170630 LW NA <NA> <NA> NA 1

<a href="#cb8-52" tabindex="-1"></a>#> 199: <NA> 20170630 OT NA <NA> <NA> NA 1

<a href="#cb8-53" tabindex="-1"></a>#> 200: <NA> 20170630 MD NA <NA> <NA> NA 1

<a href="#cb8-54" tabindex="-1"></a>#> age_in_years country_code sex init_fda_dt auth_num lit_ref

<a href="#cb8-56" tabindex="-1"></a>#> 1: 68 <NA> Female NA <NA> <NA>

<a href="#cb8-57" tabindex="-1"></a>#> 2: 58 <NA> Female NA <NA> <NA>

<a href="#cb8-58" tabindex="-1"></a>#> 3: 53 <NA> Female NA <NA> <NA>

<a href="#cb8-59" tabindex="-1"></a>#> 4: NA <NA> Female NA <NA> <NA>

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