Extreme artifacts and hard crashes appear if both plots render really close to each other in time. I think it's related to the frame buffer switching. I found opentk/GLWpfControl#58 which indicates the problem may be multiple OpenGL context objects, but a solution could be to force multiple controls to use the same context.
This issue will track adding a way to enable/disable OpenGL rendering functionality. At first I'll probably create two controls for this, but in the future something smarter may be a solution. I'm experimenting in WinForms but presumably all controls have this issue when OpenGL is employed.
Standard

OpenGL
