The very interesting option in kcachegrind (which is also the reason that the assembly view has a source reference) is that one can order by clicking on the columns, enabling you to order by costs (this way seeing "local" hotpots very fast), click on an interesting line to mark it, then order by line (source view) / address (disassembly), then use arrow-up to position on the line before the one you've marked before.

Originally posted by @GitMensch in #523 (comment)