| Term | Full Form | Definition | Meaning | Main Category | Subcategory | Country/ Region | Popularity |
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| Y | Yes | Academic & Science › Language & Linguistics |  |
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| Y | Year | Academic & Science › Units | |
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| Y | Tyrosine | Medical › Biochemistry | |
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| Y | Yttrium | Academic & Science › Chemistry | |
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| Y | Yellow | Academic & Science › Language & Linguistics | |
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| Y | Yotta | Academic & Science › Units | |
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| y | yocto | Academic & Science › Units | |
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| Y | Admittance | Academic & Science › Electrical | |
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| Y | Why | Miscellaneous › Chat & Messaging | |
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| Y2K | Year 2000 | Computing › Security | |
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| YAC | Yeast Artificial Chromosome | Medical › Genetics | |
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| YAHOO | Yet Another Hierarchical Officious Oracle | Computing › Internet | |
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| Yamaha | named after its founder, Torakusu Yamaha | Business › Companies & Corporations | |
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| YAML | YAML Ain't Markup Language | Computing › Programming & Development | |
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| YAML | Yet Another Multicolumn Layout | Computing › Programming & Development | |
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| YASH | Yamaha Artist Services Hollywood | Business › Companies & Corporations |  |
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| ybn | Yabaâna | Regional › Language Codes |  |
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| YBN | Young Boss Niggas | Arts › Musical groups | |
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| YC | Y Combinator | Business › Companies & Corporations | |
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| YC | Yellow Card | Sports & Games › Football | |
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| YC | Yellow Claw | Society & Culture › Celebrities & Famous |  |
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| YC | Yung Chris | Society & Culture › Celebrities & Famous | |
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| YC | Yacht Club | Sports & Games › Water Sports | |
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| YC | Yale College | Academic & Science › Universities & Institutions | |
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| YC | Youth Conference | Associations & Organizations › Conferences & Events | |
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