Judaic

Клиника за очне болести, Клинички центар, Ниш, Србија; 2 Клиника за очне болести, Клинички центар Србије, Београд, Србија УВОД Стра на те ла у ин тра о ку лар ним струк ту рама се бе ле же у око 40% свих пе не трант них по вре да ока. Стра но те ло у со чи ву се ди јагно сти ку је у 5-10% слу ча је ва свих ин тра о кулар них стра них те ла, а мо же би ти удру же но с из ра же ним ком пли ка ци ја ма . Ве личи на стра ног те ла, ло ка ли за ци ја, вр ста мате ри ја ла, оштри на ви да и ри зик од ин фекци је ва жни су фак то ри за до но ше ње од луке о сте пе ну хит но сти хи рур шког ле че ња па ци је на та с овим про бле ми ма . Ове повре де обич но задобијају мла ђи му шкарци. Код сва ке по вре де ин тра о ку лар ног со чи ва до ла зи до оште ће ња пред ње кап су ле, по сле че га на ста је ка та рак та раз ли чи тог сте пе на. У ве ћи ни слу ча је ва сте пен за му ће ња со чива је та кав да до во ди до знат ног оште ће ња оштри не ви да, те је по треб на опе ра ци ја ради по вра ћа ја ви да. За јед но с ка та рак том, посто ја ње лен ти ку лар них про те и на и пар тику ла у пред њој оч ној ко мо ри мо же до ве сти до по ја ве се кун дар ног гла у ко ма и из ра жене за па љењ ске ре ак ци је . Јед на од најте жих ком пли ка ци ја по сле заостајања метал ног стра ног те ла је си де ро за ока, ко ја се мо же ја ви ти из ме ђу осмог и 18. да на од повре ђи ва ња .

Universities are primary sources of new knowledge production and innovation in Serbia and crucial element for technological change in vital segments of economy. Therefore knowledge and technology transfer from universities is an extremely important factor. In this paper an introduction to the iDEA lab, student centred co-creative ecosystem is given, including its background, specific goals, and expected impact. iDEA lab represents and innovative way to link universities and industry as well as to include students in technology transfer.

age groups. METHODS: This is a retrospective review of medical charts of patients who were hospitalized due to airsoft guns ocular injuries in ten-year period (from 2000 to 2009). Patient's age, gender, duration of hospitalization, type of treatment and initial and final visual acuity were analyzed. RESULTS: Overall 92 patients with ocular injuries caused by airsoft gun pellets were hospitalized in tenyear period. In all patients only one eye was injured and there were 72 (78.3%) male patients. Injuries involved ocular adnexa, anterior and posterior segment of the eye. On initial examination 41 (44.6%) patients were presented with subconjunctival hemorrhages, 42 (45.6%) with corneal abrasion, 42 (45.6%) patients had corneal edema, 6 (6.5%) had traumatic mydriasis, 90 (97.8%) patients exhibited hyphema, 10 (10.9%) iridodialysis, in 27 (29.3%) patients high intraocular pressure (IOP) was measured, one patient had subluxation of intraocular lens (IOL) and one patient had traumatic cataract. Posterior segment findings included vitreous hemorrhage in 3 (3.3%) patients, retinal hemorrhage in 15 (16.3%) patients, retinal edema in 35 (38.0%) patients and one patient had globe rupture. Average duration of hospitalization was 5.7 days (range from 1 to 18 days). Three patients (3.3%) required eye surgery, eight patients (8.7%) had anterior chamber washout while rest of the patients were conservatively managed. Visual acuity at hospital release was significantly improved comparing to initial visual acuity, ranging from counting fingers at 1 meter to 20/60 in 7 (8.6%) patients, from 20/50 to 20/30 in 13 (16.0%) patients and from 20/25 to 20/20 in 61 (75.3%) patients. In 11 patients testing the visual acuity was not possible because of their young age. CONCLUSION: Injuries attributed to airsoft guns were confined mostly to anterior segment. There was also high percentage of severe posterior segment trauma requiring hospital admission. The most important factors in preventing such injuries are restricting access to airsoft guns, especially to minors, as well as mandatory use of protective equipment such as protective eyeglasses.

GL2011 is a naturally occurring thiol compound and a series of thiol compounds have been proposed as radioprotectors. Radioprotective efficacy of a triple intraperitoneal dose of GL2011 of 100 mg/kg body weight of Wistar rats, 30 min prior to and 3 and 6 h following irradiation (6.7 Gy) was evaluated. Four groups of animals were used, vehicle-treated non-irradiated (VN), GL2011treated and irradiated (GI), GL2011-treated and non-irradiated (GN) and vehicle-treated and irradiated (VI) (n = 30 per group). The radioprotective efficacy of GL2011 was determined by measuring 28-day survival and intestinal crypt cell survival. Neuroprotection in terms of behaviour was evaluated using the behavioural observational battery, open field test and elevated plus maze paradigm. An RNA microarray was carried out in order to show differences at the RNA level between VI and VN groups. Brain protein changes were identified using a gel-based proteomics method and major brain receptor complex levels were determined by blue-native gels followed by immunoblotting. 28-Day survival rate in VI was 30 %, in GI survival was 93 %, survival of VN and GN was 100 %. Jejunal crypt cell survival was significantly enhanced in GI. Protein-level changes of peroxiredoxin-5, Mn-superoxide dismutase 2, voltage-dependent anionselective channel protein 1, septin 5 and dopamine D2 receptor complex levels were paralleling radiation damage and protection. Taken together, the findings demonstrate that GL2011 improves survival rates and jejunal crypt survival, provides partial neuroprotection at the Electronic supplementary material The online version of this article (behavioural level and modulates proteins known to be involved in protection against oxidative stress-mediated cell damage.

Typical data mining algorithms follow a so called "black-box" paradigm, where the logic is hidden from the user not to overburden him. We show that "white-box" algorithms constructed with reusable components design can have significant benefits for researchers, and end users as well. We developed a component-based algorithm design platform, and used it for "white-box" algorithm construction. The proposed platform can also be used for testing algorithm parts (reusable components), and their single or joint influence on algorithm performance. The platform is easily extensible with new components and algorithms, and allows testing of partial contributions of an introduced component. We propose two new heuristics in decision tree algorithm design, namely removal of insignificant attributes in induction process at each tree node, and usage of combined strategy for generating possible splits for decision trees, utilizing several ways of splitting together, which experimentally showed benefits. Using the proposed platform we tested 80 component-based decision tree algorithms on 15 benchmark datasets and present the results of reusable components' influence on performance, and statistical significance of the differences found. Our study suggests that for a specific dataset we should search for the optimal component interplay instead of looking for the optimal among predefined algorithms.

Background In traffic accidents, eye injuries occur as isolated or with polytrauma. They may involve just one eye, but simultaneous injuries to both eyes do happen occasionally. The aim of our paper was to reveal the risk factors, in an effort to reduce the number of such accidents and to prevent bilateral ocular damage. Methods All patients hospitalized at the Clinic of Eye Diseases, Clinical Center of Serbia, Belgrade, due to traffic accidents with bilateral eye injuries in a period of 9 years from the beginning of 2000 to the end of 2008 were analyzed. Results In this 9-year period, a total of 36 patients were hospitalized and treated for bilateral ocular injury (72 eyes). There were 23 males among them, the male-female ratio being 1.8:1. Mean age was 33.9 years. The occupations of injured persons were the following: the most common were workers-15, followed by clerks-seven, while less common were pupils, students, pensioners and housewives-three of each of them, and farmers-two. Front-seat passengers were the most common among the injured-20 (55.6%), then drivers-15 (41.7%), with only one passenger from the back seat on the right side (2.7%). As many as 33 (91.7%) of them failed to fasten their seat belts, while 18 (50.0%) were drunk. Penetrating bulbar injuries or eyeball ruptures were predominant-66.7%, while blunt injuries were found in only two (2.8%) eyes in one single person; but in 22 cases (30.5%) there was adnexal damage, too.

University students are usually taught data mining through black-box data mining algorithms, which hide the algorithm's details from the user and optionally allow parameter adjustment. This minimizes the effort required to use these algorithms. On the other hand, white-box algorithms reveal the algorithm's structure, allowing users to assemble algorithms from algorithm building blocks. This paper provides a comparison between students' acceptance of both black-box and white-box decision tree algorithms. For these purposes, the technology acceptance model is used. The model is extended with perceived understanding and the influence it has on acceptance of decision tree algorithms. An experiment was conducted with 118 senior management students who were divided into two groups-one working with black-box, and the other with white-box algorithms-and their cognitive styles were analyzed. The results of how cognitive styles affect the perceived understanding of students when using decision tree algorithms with different levels of algorithm transparency are reported here.

Many decision tree algorithms were proposed over the last few decades. A lack of publishing standards for decision tree algorithm software produced a large time gap between algorithm proposals and their wider application in practice. Non-existence of common repository for storing algorithms and their parts led to a need to re-implement these algorithms from a scratch when they had to be implemented on a different platform. This makes the comparison between algorithms and their partial improvements vague. In addition, combinations and interactions between different algorithm parts haven't been analyzed thoroughly. Reusable component design of decision tree algorithms has been recently suggested as a potential solution to these problems. In this paper we describe an architecture for component-based (white-box) decision tree algorithm design, and we present an open-source framework which enables design and fair testing of decision tree algorithms and their parts. This architecture and developed platform can provide the research community with a common codebase for storing, designing, and evaluating decision tree algorithms (traditional, multivariate and hybrid) and their partial improvements. It is intended for data mining practitioners, algorithm and software developers, and as well for students, as a technology enhanced learning tool.

It is expected in the future that Robots will be reliable partners of humans in accomplishing different activities and thereby to express high degree of mutual understanding, compatibility and coordination between each-other. In that sense, along with the advance physical abilities, personal robots will be required to perceive, understand and express (use) the emotions as well as to react in a socially accepted manner by enhancing in such a way their interaction with social environment. In a word, robot is expected to possess a character, i.e. personality traits like human as live model. Possessing of character is of great importance for robot-partners due to reason of better acceptance amongst the humans as well as in order to make robots to be able of better understanding people behavior. The fact proved is that high degree of interpersonal compatibility, emotive complementarity and mutual understanding within a team or group ensures better outcomes than the team consists of superior individuals of high intelligence quotients (IQs). People choose partners in a way to be complementary with them and ones that manifest in general sense high level of mutual understandings and agreements. On the other hand, people do not enjoy the opposed persons of incompatible or conflict character. From these reasons, we investigate in the paper the answers if possible and how to give robots different characters i.e. attributes of human personalities.

We propose a method for designing a partitioning clustering algorithm from reusable components that is suitable for finding the appropriate number of clusters (K) in microarray data. The proposed method is evaluated on 10 datasets (4 syntetic and 6 real-word microarrays) by considering 1008 reusable-componentbased algorithms and four normalization methods. The best performing algorithm were reported on every dataset and also rules were identified for designing microarray-specific clustering algorithms. The obtained results indicate that in the majority of cases a data-tailored clustering algorithm design outperforms the results reported in the literature. In addition, data normalization can have an important influence on algorithm performance. The method proposed in this paper gives insights for design of divisive clustering algorithms that can reveal the optimal K in a microarray dataset.

Po vre de or bi te oka iza zva ne pro di ra wem i zadr ža va wem stra nog te la ni su ta ko èe ste. Sva ka pe ne tri ra ju aea po vre da kod ko je se sum wa na posto ja we stra nog te la u or bi ti je te ška i va žna, ka ko s kli niè kog sta no vi šta, ta ko i s me di kole gal nog aspek ta . Te ži na po vre de mo že bi ti raz li èi ta, a za vi si od osobina stra nog te la: veli èi ne, ob li ka, pri ro de i br zi ne ko jom je do spelo u or bi tu. Ve li èi na i br zi na stra nog te la odre ðu ju we go vu ki ne tiè ku ener gi ju, od èe ga za visi da li aee se ono za dr ža ti u or bi ti ili aee proaei kroz wu i pro dre ti u okol ne struk tu re, si nuse i kra ni jum .

In sti tut za oè ne bo le sti "Prof. dr Ðor ðe Ne šiae", Kli niè ki cen tar Sr bi je, Be o grad KRATAK SADRŽAJ: Ciq ra da je pri kaz us peš no spro ve de ne de kom pre si je or bi te kod or bi tal nog he ma to ma. Muš ka rac star 51 go dinu za dobio je kon tuzionu po vredu de snog oka pri pa du na sla vinu u ka di. Doš lo je do stva rawa ve likog orbi tal nog he ma to ma sa pro tru zi jom, ogra ni èewem po kre ta oè ne ja bu èi ce, bo lom, di plo pi ja ma, na bo rom re ti ne zbog kompre si je he ma to ma na bul bus i re ti nal nim he mo ra gi ja ma, po vi še nog in tra o ku lar nog pri ti ska i pa da vid ne oš tri ne na 2/60. Me sec da na je le èen me di ka ment nom te ra pi jom, ali bez vi dqi vih re zul ta ta. Po sle me sec da na od po vre de iz vr šena je ope ra ci ja, i to predwe-dowa tran sku ta na or bi to to mi ja. Ta da su eks tra ho va ni he ma tom i deo ma snog tki va or bi te. Od mah po sle ope ra ci je doš lo je do po vla èewa bul bu sa pre ma po za di i ne stan ka eg zof tal mu sa, a na red nih da na i do uspo sta vqawa po kre tqi vo sti oè ne ja bu èi ce, gu bit ka na bo ra re ti ne uz po ste pe no po vla èewe he mo ra gi ja, nor ma li zo vawa in tra o ku lar nog pri ti ska, ne stan ka bo la i di plo pi ja i vra aeawa vid ne oš tri ne na nor ma lu. Ovim ra dom je po ka za no da de kom pre si ja or bi te kod or bi tal nog he ma to ma mo že bi ti us peš na i u po znom pe ri o du, od no sno me sec da na po sle povre de. Na rav no, ope ra ci ju bi tre ba lo da iz vo di sa mo is ku san or bi tal ni hi rurg. Kquè ne re èi: kon tu zi ja or bi te, or bi tal ni he ma tom, de kom pre si ja or bi te.

Uvod U radu su analizirani neki od faktora koji su značajni za nastanak mehaničkih povreda očne jabučice. Ciq rada Osnovni ciq ove analize je prevencija i smawewe broja povreda oka. Metod rada Analizirane su mehaničke povrede oka kod bolesnika koji su bolnički lečeni na Institutu za očne bolesti Kliničkog centra Srbije u Beogradu u periodu od pet godina. Bolnički su lečeni samo bolesnici koji su imali teške po vrede oka. Od parametara su analizirani: pol i starost bolesnika, wihovo zanimawe, mesto stanovawa, vreme kada se po vreda desila, i to po mesecima, danima i satima, mesto i način gde su se povrede desile, kao i oštrina vida na prijemu. Analizirana je i vrsta povrede (kontuziona ili penetrantna) sa svim komplikacijama. Na kraju je dato vreme kada je izvr šena primarna hirurška obrada rane na oku ako je to bilo potrebno. Rezultati U toku pet godina su, zbog mehaničke povrede oka, bolnički lečena 1.642 bolesnika (1.381 osoba muškog i 261 osoba ženskog pola). Od svih povređenih 861 bolesnik (52,4%) je bio iz grada, a 781 bolesnik (47,6%) je živeo na selu. Sko ro podjednako je povređivano i desno i levo oko, dok su kod 21 bolesnika (1,3%) bila povređena oba oka istovremeno. Po vrede su se dešavale u svim starosnim kategorijama, ali najčešće kod odraslih radno aktivnih osoba starosti 1655 godi na (60,8%). Među decom uzrasta do 15 godina bilo je 19,4% povređenih. Najčešće su se povređivali radnici (39,8%), a zatim učenici (17,5%). Drvo je bilo uzrok povrede kod 21,8% ispitanika, oštri i šiqati predmeti kod 17,2% ispitanika, čekić i metal kod 14,2%, staklo kod 11,6%, a drugi uzročnici kod 35,2% povređenih ispitanika. Bilo je i vrlo retkih uzročnika po vrede oka, kao što su rajf, ujed psa, kqun petla itd. Prema mesecima i danima, povrede su bile skoro podjednako raspore đene, a prema dobu dana, čak 77,4% povreda se desilo od 10 sati pre podne do 10 sati uveče. Najviše povreda (43,5%) se desi lo pri obavqawu posla van profesionalnog radnog mesta, dok je na poslu zadobijeno 24,5% povreda. Najveći broj bolesni ka (32,9%) je pri prijemu imao oštrinu vida L+P+ (osećaj svetla sa tačnom projekcijom), ali je oštrina vida na prijemu bi la od amauroze do 1,0. Zabeleženo je 746 kontuzionih povreda (45,4 %) i 870 penetrantnih (53,0%) , dok su ostalo bile povre de pomoćnih organa oka. Najveći broj primarnih obrada rane (67,1%) izvršen je u toku prva 24 časa od povrede. Zakqučak Rezultati ove studije su pokazali da se najviše povređuje radno aktivno stanovništvo i učenici, da se mu škarci pet puta češće povređuju od žena, da su drvo, oštri predmeti i staklo najčešći uzročnici povreda, da je podjed nak broj kontuzionih i penetrantnih povreda i da je neophodna primarna obrada rane preduzimana najčešće u prva 24 časa od povrede. Daqom analizom ovih faktora može se zakqučiti da su se mnoge povrede mogle prevenirati, čime bi se sprečili dugotrajno lečewe i troškovi lečewa, a, ono što je najvažnije, mogla se izbeći trajna invalidnost zbog smawe wa sposobnosti vida ili slepila na povređenom oku.