Mona Hetta

Fayoum University, Pharmacognosy, Dean of the Faculty

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Prof. Mona H. Hetta, Dean of Faculty of Pharmacy, Fayoum University, 2015 – till now. She is the founder of this Faculty. Prior to this she acted as Dean of Faculty of Pharmacy, Beni-Suef University, 2014-2015

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Daniel Robledo

Centro de Investigacion y Estudios Avanzados del IPN

Ivan L . Lawag

The University of Western Australia

Salman Ahmed

University of Karachi

Fouad Saleh R Al-Suede

Universiti Sains Malaysia

Dr/ Shaimaa Abdelgawad

Fayoum University

Md. Jamal Hossain

State university of Bangladesh, Dhaka

Jana Javornik

University of East London

Gwen Robbins Schug

University of North Carolina at Greensboro

Gabriel Gutierrez-Alonso

University of Salamanca

John Sutton

Macquarie University

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Holistic Overview of the Phytoconstituents and Pharmacological Activities of Egyptian Riverhemp [Sesbania sesban (L.) Merr.]: A Review

Natural Product Communications

Background: Sesbania sesban (L.) Merr. (Family: Fabaceae), commonly known as Egyptian riverhemp, ... more Background: Sesbania sesban (L.) Merr. (Family: Fabaceae), commonly known as Egyptian riverhemp, is a well-known plant widely distributed through Egypt, the rest of Africa and Asia. S. sesban leaves have been traditionally used as an anthelmintic, demulcent, purgative, and anti-inflammatory agent in the treatment of eczema, in addition to its agricultural uses. Objective: The aim of this review is to present a comprehensive account of the isolated constituents from S. sesban leaves, along with the correlation between those constituents and the reported biological activities. Methods: This search was performed using SciFinder, Google, Google Scholar, and CrossRef websites using the following keywords: “ Sesbania sesban,” “ Sesbania aegyptiaca,” “Egyptian riverhemp,” “phytochemistry,” “phytochemical constituents,” “isolation,” “steroids,” “triterpenoids,” “saponins,” “coumarins,” “lipoidal contents,” “pharmacological properties,” “biological activities,” “therapeutic uses,” and “revie...

Phytochemical Investigation of Egyptian Spinach Leaves, a Potential Source for Antileukemic Metabolites: In Vitro and In Silico Study

Revista Brasileira de Farmacognosia

Spinacia oleracea L., Amaranthaceae, leaves cultivated in Egypt demonstrated a potential antileuk... more Spinacia oleracea L., Amaranthaceae, leaves cultivated in Egypt demonstrated a potential antileukemic activity against the chronic myeloid leukemia, K562 cell line. Thus, the aim of this study is to carry out a phytochemical investigation of S. oleracea leaves as well as the isolation of its antileukemic phytoconstituents. Phytochemical investigation of S. oleracea leaves resulted in the isolation of seventeen known compounds. The biological study revealed that compounds hexaprenol, phytol, and 18-[(1-oxohexadecyl) oxy]-9-octadecenoic acid exhibited a remarkable antiproliferative activity against K562 cells in vitro. A mechanistic in silico study showed that hexaprenol, phytol, and 18-[(1-oxohexadecyl) oxy]-9-octadecenoic acid exhibited a strong binding affinity towards topoisomerase (docking score −12.50, −9.19, and −13.29 kcal/mol, respectively), and showed as well a strong binding affinity towards Abl kinase (docking score −11.91, −9.35, and −12.59 kcal/mol, respectively). Molecu...

Mona Hetta

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