Papers by anastasia mitsea

Journal of Clinical Densitometry, 2007
The aim of this study was to measure the accuracy of porosity of the mandibular cortex on dental ... more The aim of this study was to measure the accuracy of porosity of the mandibular cortex on dental panoramic radiographs (DPRs) in diagnosis of osteoporosis, alone and in combination with a clinical risk index. Six hundred seventy-one women (45e70 yr) were recruited in the study, and dual-energy X-ray absorptiometry of the hip and lumbar spine was performed. A clinical index of osteoporosis risk (OSIRIS) and a DPR were obtained for each subject. The cortical appearance on the DPR was classified using the mandibular cortical index (MCI) by 5 observers. receiver operating characteristic (ROC) curve analysis was performed with calculation of area under the ROC curve (AUC) and sensitivity and specificity at various thresholds. Complete data were available for 653 subjects, of whom 21.6% had osteoporosis. The AUC for OSIRIS was 0.838. When used alone as the diagnostic test, MCI AUC for the 5 observers ranged from 0.560 to 0.670, significantly less than OSIRIS. Intraobserver and interobserver repeatability of MCI assessment was inconsistent. We conclude that MCI has limited value for osteoporosis diagnosis, being most appropriate as a method of fortuitous case-finding.

Age-at-death is an essential biological parameter necessary for the identification of human remai... more Age-at-death is an essential biological parameter necessary for the identification of human remains. The most reliable methods for estimating age-at -death from adult skeletal remains are based on the identification of degenerative changes in bones and teeth throughout life. Current techniques are based on the study of morphological changes that occur in the pubic symphysis, the auricular surface of the ilium, and the sternal end of the fourth rib. However, in both forensic and archaeological settings it is not uncommon to recover the pelvis and the ribs in a fragmentary state. In this case, teeth can be used as an additional tool for age estimation as they are resistant to destruction and fragmentation in comparison to skeletal tissues. Lamendin et al. developed a method for age estimation from teeth based on root transparency and periodontosis. They developed an equation for determining age-at-death independently of ancestry or sex. However, Prince & Ubelaker evaluated this techni...

The knowledge of the extent of the maxillary sinus is very important for the dentist who is conte... more The knowledge of the extent of the maxillary sinus is very important for the dentist who is contemplating extractions, root canal treatments or apicectomies in teeth known to be in proximity to the lower wall of the sinus. In order to evaluate the configuration and the extent of the sinus in edentulous areas of the maxilla, 950 orthopantomograms were examined, belonging to patients who randomly visisted the Oral Diagnosis Clinic of the Dental School of Athens University. Of these, 301 radiographs were selected for this investigation, on the basis of the following criteria: 1) detailed and clear image of the maxillary sinus, on both sides. 2) existence of edentulous sites in the maxilla and specifically in areas approximating the sinus. On these orthopantomographs the following data were recorded:distance of the floor of the maxillary sinus from the crest of the alveolar bone, shape and symmetry of the sinuses on both sites. After statistical analysis of the data, the findings were a...

Journal of Clinical and Experimental Dentistry, 2015
To investigate the frequency of non-syndromic distomolars in a Greek population sample. The study... more To investigate the frequency of non-syndromic distomolars in a Greek population sample. The study population of this retrospective study consisted of 859 Orthopantomograms (OPGs) of 425 male and 434 female patients, attended the Department of Oral Diagnosis and Radiology, Dental School of Athens seeking for treatment. The OPGs were taken as a part of the patients treatment planning. Patients' mean age was 33.57 years. Exclusion criteria from this study was cleft lip ± palate and diseases associated with systemic conditions and syndromes (such as cleidocranial dysplasia and Gardner syndrome). OPGs were only included in the study if at least one 3rd molar was present. The data collected were the number of 3rd molars, the number of distomolars, the age and the gender of each patient, information concerning previous extraction of 3rd molars. Statistical evaluation of the data included descriptive and bivariate analyses (Chi-square test and Spearman's rho correlation coefficient). In an attempt to further estimate the correlation between the presence of upper and lower 3rd conditions we assumed that the absence of 3rd molars, the presence of 3rd molars, and the presence of distomolars was ordinal in nature and we calculated the Spearman Correlation Coefficient. The number of distomolars was greater in the maxilla than in the mandible. In the maxilla the distomolars were located almost equally in both left and right side. It was more possible lower left distomolars to be present in males than in females. Furthermore, males present higher prevalence of supernumerary teeth than females. Early radiographic diagnosis of distomolars is fundamental so as to prevent complications such malocclusion, delayed eruption or displacement root or/ and resorption of adjacent teeth, pulp necrosis, follicular cyst, pain. Non syndromic, distomolars, supernumerary molars, fourth molars.

The Rubistein-Taybi syndrome (RTS) or Broad Thumb-Hallux Syndrome (BTHS) is a congenital conditio... more The Rubistein-Taybi syndrome (RTS) or Broad Thumb-Hallux Syndrome (BTHS) is a congenital condition with many malformations, originally described in 1963. Since then several hundred patients with RTS have been reported. The syndrome is characterized by the association of mental and growth redartation, typical facial appearance and broad sort terminal phalanges of the thumbs and halluces with of without angulation deformity. The characteristic facial appearance of the syndrome has beaked or streight nose, antimogoloid slant of palpebral fissures, ptosis, low set angulated ears, apparent of clinical hypertelorism and grimacing smile, singificant behavior problems due to mental, motor, social and language retardation. The main non-dental oral findings are thin upper lip, small oral opening, retro/micrognathia and apparently highly arched palate, whereas cleft palate can be part of the syndrome. Other findings as hypodontia, hyperdontia, and talon cusps are also found. The last finding s...

The Journal of forensic odonto-stomatology
Age-at-death is an essential biological parameter necessary for the identification of human remai... more Age-at-death is an essential biological parameter necessary for the identification of human remains. The most reliable methods for estimating age-at -death from adult skeletal remains are based on the identification of degenerative changes in bones and teeth throughout life. Current techniques are based on the study of morphological changes that occur in the pubic symphysis, the auricular surface of the ilium, and the sternal end of the fourth rib. However, in both forensic and archaeological settings it is not uncommon to recover the pelvis and the ribs in a fragmentary state. In this case, teeth can be used as an additional tool for age estimation as they are resistant to destruction and fragmentation in comparison to skeletal tissues. Lamendin et al. developed a method for age estimation from teeth based on root transparency and periodontosis. They developed an equation for determining age-at-death independently of ancestry or sex. However, Prince & Ubelaker evaluated this techni...
Excessive alcohol (1, 2) consumption has long been recognized as a risk factor for osteoporosis. ... more Excessive alcohol (1, 2) consumption has long been recognized as a risk factor for osteoporosis. Chronic alcohol consumption has an adverse effect on the function and differentiation of osteoblasts, favouring the production of adipocytes instead, whereas moderate alcohol consumption has a beneficial effect on bone mineral density (BMD) by increasing serum estrogen (3). Rapuri et al.

The aim of this study was to measure the accuracy of porosity of the mandibular cortex on dental ... more The aim of this study was to measure the accuracy of porosity of the mandibular cortex on dental panoramic radiographs (DPRs) in diagnosis of osteoporosis, alone and in combination with a clinical risk index. Six hundred seventy-one women (45e70 yr) were recruited in the study, and dual-energy X-ray absorptiometry of the hip and lumbar spine was performed. A clinical index of osteoporosis risk (OSIRIS) and a DPR were obtained for each subject. The cortical appearance on the DPR was classified using the mandibular cortical index (MCI) by 5 observers. receiver operating characteristic (ROC) curve analysis was performed with calculation of area under the ROC curve (AUC) and sensitivity and specificity at various thresholds. Complete data were available for 653 subjects, of whom 21.6% had osteoporosis. The AUC for OSIRIS was 0.838. When used alone as the diagnostic test, MCI AUC for the 5 observers ranged from 0.560 to 0.670, significantly less than OSIRIS. Intraobserver and interobserver repeatability of MCI assessment was inconsistent. We conclude that MCI has limited value for osteoporosis diagnosis, being most appropriate as a method of fortuitous case-finding.

This paper presents a case of a late discovery of a motorcycle accident victim. The fact that the... more This paper presents a case of a late discovery of a motorcycle accident victim. The fact that the remains were almost skeletonized required the input of several disciplines in order to identify the victim. Therefore, anthropology, odontology, facial reconstruction, and genetics were employed. It was found that the victim was male, between the ages of 35 to 55 with a number of healed fractures. In addition, perimortem trauma with a pattern that was consistent with a motorcycle accident was found in the head and upper body regions. Dental findings included a tooth out of alignment with the rest of the dental arcade, as well as a heavily decayed tooth that was replaced by a dental bridge. Both of these findings were supported by ante mortem photographs of the victim. A two-dimensional facial reconstruction was carried out and produced a very good likeness of the deceased. The above findings were confirmed by DNA analysis that matched a bone sample to those of the family of the deceased...

Sex assessment from tooth measurements can be of major importance for forensic and bioarchaeologi... more Sex assessment from tooth measurements can be of major importance for forensic and bioarchaeological investigations, especially when only teeth or jaws are available. The purpose of this study is to assess the reliability and applicability of establishing sex identity in a sample of Greek population using the discriminant function proposed by F.W. Rösing, G. Paul, and S. Schnutenhaus in 1995. The study comprised of 172 dental casts derived from two private orthodontic clinics in Athens. The individuals were randomly selected and all had clear medical history. The mesiodistal crown diameters of all the teeth were measured apart from those of the 3rd molars. The values quoted for the sample to which the discriminant function was first applied were similar to those obtained for the Greek sample. The results of the preliminary statistical analysis did not support the use of the specific discriminant function for a reliable determination of sex by means of the mesiodistal diameter of the...

Journal of Clinical Densitometry, 2007
The aim of this study was to measure the accuracy of porosity of the mandibular cortex on dental ... more The aim of this study was to measure the accuracy of porosity of the mandibular cortex on dental panoramic radiographs (DPRs) in diagnosis of osteoporosis, alone and in combination with a clinical risk index. Six hundred seventy-one women (45e70 yr) were recruited in the study, and dual-energy X-ray absorptiometry of the hip and lumbar spine was performed. A clinical index of osteoporosis risk (OSIRIS) and a DPR were obtained for each subject. The cortical appearance on the DPR was classified using the mandibular cortical index (MCI) by 5 observers. receiver operating characteristic (ROC) curve analysis was performed with calculation of area under the ROC curve (AUC) and sensitivity and specificity at various thresholds. Complete data were available for 653 subjects, of whom 21.6% had osteoporosis. The AUC for OSIRIS was 0.838. When used alone as the diagnostic test, MCI AUC for the 5 observers ranged from 0.560 to 0.670, significantly less than OSIRIS. Intraobserver and interobserver repeatability of MCI assessment was inconsistent. We conclude that MCI has limited value for osteoporosis diagnosis, being most appropriate as a method of fortuitous case-finding.

Dentomaxillofacial radiology is a useful tool in forensic science to reveal characteristics of th... more Dentomaxillofacial radiology is a useful tool in forensic science to reveal characteristics of the structures of the dentomaxillofacial region. Postmortem radiographs are valuable to the forensic odontologist for comparison with antemortem radiographs, which are the most consistent part of the antemortem records that can be transmitted during forensic examination procedures. By using dentomaxillofacial radiology we can, therefore, give answers to problems dealing with identification cases, mass disasters and dental age estimation. We present the contribution of dentomaxillofacial radiology to the forensic sciences through two cases of deceased persons, where identification was based on information provided by radiographs. The right performance, interpretation and reportage of dentomaxillofacial radiological examination and procedures can be extremely valuable in solving forensic problems. (J Forensic Odontostomatol 2007;25:12-6)
Please cite this article in press as: Mitsea, A.G., et al., Sex determination by tooth size in a ... more Please cite this article in press as: Mitsea, A.G., et al., Sex determination by tooth size in a sample of Greek population. HOMO -J. Comp. Hum. Biol. (2014), http://dx.
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Papers by anastasia mitsea