hypergranularとは 意味・読み方・使い方

形容詞

hypergranular ‎(not comparable)

1. Excessively granular
   • 2016 January 27, “Addition of Arsenic Trioxide into Induction Regimens Could Not Accelerate Recovery of Abnormality of Coagulation and Fibrinolysis in Patients with Acute Promyelocytic Leukemia”, in PLOS ONE^[1], DOI:10.1371/journal.pone.0147545:

     It is characterized by an excess of abnormal hypergranular promyelocytes in the bone marrow and other hematopoietic organs, and chromosomal translocation t(15;17)(q22;q21) leading to fusion of the genes encoding promyelocytic leukemia protein(PML) and retinoic acid receptor alpha (RARα) to generate the PML-RARα oncoprotein [2 ].