dysgranulocytopoiesisとは 意味・読み方・使い方

名詞

dysgranulocytopoiesis (uncountable)

1. (medicine) Dysfunctional granulocytopoiesis; defective production of granulocytes.
   • 1995, Takeo Nomura, Myelodysplastic syndromes: advances in research and treatment : proceedings of the International Symposium on Myelodysplastic Syndromes, National Cancer Center, Tokyo, Japan, 13-14 October 1994, Elsevier Science Ltd (ISBN 9780444820501)

     RA is defined by anemia, reticulocytopenia and normo- or hypercellular bone marrow (BM) with dyserythropoiesis and infrequently dysgranulocytopoiesis.

   • 2000, Helmut Löffler, Johann Rastetter, Atlas of Clinical Hematology, Springer Science & Business Media (ISBN 9783642980206)

     The bone marrow is hypercellular with variable hyperplasia of erythropoiesis or granulocytopoiesis. Dyserythropoiesis, dysgranulocytopoiesis, and/or dysmegakaryocytopoiesis is invariably present. Ringed sideroblasts may be found.

   • 2012, Wolfgang Hiddemann, Thomas Büchner, Bernhard Wörmann, Jörg Ritter, Ursula Creutzig, William Plunkett, Acute Leukemias VII: Experimental Approaches and Novel Therapies, Springer Science & Business Media (ISBN 9783642719608), page 37

     This would explain why dyserythropoiesis and anemia are virtually always present in MDS patients, whereas dysgranulocytopoiesis and dysmegakaryocytopoiesis are often less prominent.