cyclopropylatedとは 意味・読み方・使い方

形容詞

cyclopropylated ‎(not comparable)

1. (有機化学) Modified by the addition of cyclopropyl group(s)
   • 2013 September 15, Anita Y. M. Howe, Srikanth Venkatraman, “The Discovery and Development of Boceprevir: A Novel, First-generation Inhibitor of the Hepatitis C Virus NS3/4A Serine Protease”, in Journal of Clinical and Translational Hepatology^[1], volume 1, DOI:10.14218/JCTH.2013.002XX:

     Cyclization of the N-methyl group to a P2 cyclopropyl group generated the cyclopropylated Analog 8, which had greater enzyme-binding affinity ( Ki * = 11 nmol/L) than Analog 6.