FK 506 binding proteinとは 意味・読み方・使い方

A drug delivery device comprises the implantable intraluminal medical device and an agent which is releasably affixed to the implantable intraluminal medical for treating inflammations, released for a sustained period of time within the range of 2 to 6 weeks and comprises an analog, etc., binding to an FKBP12 (FK 506-binding protein) that is a high-affinity cytosolic protein and having the same pharmacological characteristics as those of rapamycin.例文帳に追加

移植可能な内腔内医療装置で炎症治療のために放出可能に固定されている薬剤であって、２〜６週にわたり放出され、高親和性サイトゾル蛋白であるＦＫＢＰ１２に結合してラパマイシンと同じ薬理特性を持つ類似体等を含む薬剤の送達装置。 - 特許庁

This pharmaceutical composition contains a nonimmunosuppressive neurotrophic compound (such as an N-glyoxylprolyl ester) which has affinity to an FK 506 binding protein, (FKBP)-type immunophilin exhibiting rotamase activity and inhibits the rotamase activity of the immunophilin, and is useful for treating neurological disorders (such as Alzheimer's disease Parkinson's disease and amyotrophic lateral sclerosis).例文帳に追加

ロタマーゼ活性を示すＦＫＢＰ型イムノフィリンに親和性を有し、該イムノフィリンのロタマーゼ活性を阻害する非免疫抑制性の神経栄養化合物（Ｎ−グリオキシルプロリルエステル等）を含有する神経学的障害（アルツハイマー病，パーキンソン病，筋萎縮側索硬化等）を治療するための薬剤組成物。 - 特許庁