Dr. Nihar R A N J A N Kar
I am Dr. Nihar Ranjan Kar, M.Pharm.,Ph.D.,having about 15 years of Teaching and Research experience in these following subjects like Pharmaceutics, Dispensing Pharmacy, Hospital Pharmacy, Industrial Pharmacy, Pharmaceutical Technology, Pharmaceutical Jurisprudence, Physical Pharmacy, Pharmaceutical Engineering, Biopharmaceutics and Pharmacokinetics, Novel Drug Delivery System, Social and Preventive Pharmacy, Human Anatomy and Physiology, Pharmacognosy, Pharmaceutical Biotechnology etc. My expertise includes Formulations and Evaluation of Sustained and Controlled Drug Delivery System, Floating Tablets, Colon Specific Drug Delivery System, Microencapsulation etc. Along with teaching experience, I have also managed different other works related to teaching profession like Course- Co-ordinator, Examination Incharge, Principal in Charge, External Centre Supervisor, Centre Superintendent etc. I am also a permanent life members in Association Pharmaceutical Teachers in India(APTI) and Indian Pharmaceutical Graduates Association(IPGA).
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opportunities, especially in rural areas with high unemployment rates. The emergence of new
biopharmaceuticals has increased interest in medicinal plants and their products over the years.
Various agricultural industry sectors are involved in medicinal plant cultivation, including
harvesting, processing, research and development, manufacturing, and production. Furthermore,
the plan emphasizes the establishment of small businesses, fostering self-employment, and
advancing the local economy. Additionally, these efforts are aimed at conserving biodiversity,
promoting sustainable resource use, controlling environmental degradation, and preserving
medicinal herb knowledge. A number of challenges exist in this effort, including a lack of
comprehensive training and technical skills, the inability to establish efficient market links, and the
inability to implement excellent quality control measures. To encourage a suitable environment for
the sustainable development of medicinal plants, it is essential that various stakeholders, including
the government, research institutions, industry participants, and local communities should come
together and have some collaborative efforts.
bioavailability of drug Telmisartan by enhancing its solubility. It is a drug that belongs to
BCS class II and has high permeability but low solubility, which is an anti-hypertensive agent.
As it is low soluble its generally showing poor bioavailability. Materials/Methods:-An effort
was made to improve dissolution rate through the preparation of solid dispersions of
Telmisartan with water soluble carries like polyethylene glycol and beta cyclodextrin by
solvent evaporation method, melt evaporation method, kneading method. Nine formulation
like were prepared in the ratio of 1:1, 1:3,1:5(drug : polymer). Results/Discussion:-
Evaluation tests like physiochemical parameters, wettability and in vitro dissolution study
were done accordingly. All of the polymers were found to be efficient in speeding the
dissolution of Telmisartan in solid dispersions as compared to the pure drug. Additional FTIR spectroscopy, different scanning calorimetry, and X-ray diffractometry investigations
were carried out to characterise the drug and solid dispersion. Formulation F9 was found as
best among all.
opportunities, especially in rural areas with high unemployment rates. The emergence of new
biopharmaceuticals has increased interest in medicinal plants and their products over the years.
Various agricultural industry sectors are involved in medicinal plant cultivation, including
harvesting, processing, research and development, manufacturing, and production. Furthermore,
the plan emphasizes the establishment of small businesses, fostering self-employment, and
advancing the local economy. Additionally, these efforts are aimed at conserving biodiversity,
promoting sustainable resource use, controlling environmental degradation, and preserving
medicinal herb knowledge. A number of challenges exist in this effort, including a lack of
comprehensive training and technical skills, the inability to establish efficient market links, and the
inability to implement excellent quality control measures. To encourage a suitable environment for
the sustainable development of medicinal plants, it is essential that various stakeholders, including
the government, research institutions, industry participants, and local communities should come
together and have some collaborative efforts.
bioavailability of drug Telmisartan by enhancing its solubility. It is a drug that belongs to
BCS class II and has high permeability but low solubility, which is an anti-hypertensive agent.
As it is low soluble its generally showing poor bioavailability. Materials/Methods:-An effort
was made to improve dissolution rate through the preparation of solid dispersions of
Telmisartan with water soluble carries like polyethylene glycol and beta cyclodextrin by
solvent evaporation method, melt evaporation method, kneading method. Nine formulation
like were prepared in the ratio of 1:1, 1:3,1:5(drug : polymer). Results/Discussion:-
Evaluation tests like physiochemical parameters, wettability and in vitro dissolution study
were done accordingly. All of the polymers were found to be efficient in speeding the
dissolution of Telmisartan in solid dispersions as compared to the pure drug. Additional FTIR spectroscopy, different scanning calorimetry, and X-ray diffractometry investigations
were carried out to characterise the drug and solid dispersion. Formulation F9 was found as
best among all.