Objective: Anaphylaxis is under-recognized and undertreated by physicians, indicating critical kn... more Objective: Anaphylaxis is under-recognized and undertreated by physicians, indicating critical knowledge gaps. This study aimed to assess the knowledge levels of anaphylaxis among family physicians (FPs) as they are the primary first-line healthcare providers and identify the factors influencing their knowledge levels. Materials and Methods: A cross-sectional study using an internet-based Google Forms questionnaire was conducted among voluntary FPs in Sivas, Turkey. Demographic features, including age, years in practice, and career position, and knowledge related to the diagnosis and management of anaphylaxis in children were assessed. Results: A total of 140 FPs participated in the survey (34 [24.3%] general practitioners [GPs], 20 [14.3%] contracted family physicians [CFPs], 74 [52.9%] residents in training [RITs], and 12 [8.6%] specialists). The number of participants who correctly answered all questions regarding diagnosis, acute treatment, and epinephrine auto-injector use was 11 (7.9%), 52 (37.4%), and 27 (19.3%), respectively. In diagnosing anaphylaxis, 100 (72.5%) participants were unaware that anaphylaxis can occur without skin manifestations, and only 48 (34.8%) identified gastrointestinal symptoms as a possible anaphylaxis presentation. RITs (11, 14.9%) and specialists (2, 16.7%) had better performance on the questionnaire, with higher proportions of participants who answered all questions correctly, compared to GPs (2, 5.9%) and CFPs (1, 5.0%). Attendance at an educational activity in the last year was the only independent factor associated with answering all questionnaire items correctly. Conclusion: There is a need to improve anaphylaxis recognition and management among all FPs regardless of their career position and work experience, underlining the importance of regular and updated educational interventions.
Archives of Gynecology and Obstetrics, Feb 18, 2023
Background: The purpose of this study to determined women's perceptions of the vulva with the cri... more Background: The purpose of this study to determined women's perceptions of the vulva with the criteria de ned in the literature for the ideal vulva and determine their relationship with anatomical measurements in order to determine the extent to which women's perceptions of normal align with our aesthetic standards of normality. Methods: First of all, a questionnaire was applied to all participants. The items of the data collection form were included personal information, obstetric and gynecological information, their perceptions of their external genitalia and any physical, sexual, psychological, and hygiene problems they experience. Then examination and measurements of the external genitalia were performed. Results: The majority of participants considered their genitalia normal (n=101, 89.4%), while 12 participants (10.6%) considered them abnormal. Statistical analyses showed that women's perception of their genitalia as normal in appearance and size was associated with labia minora asymmetry (p=0.023 and p=0.006, respectively) and hyperpigmentation (p=0.010 and p=0.047, respectively) but not with labia minora measurements or protrusion (p>0.05) Conclusions : Although there is a tendency in the eld of aesthetic surgery to de ne ideals and aesthetic standards for all parts of the body, our de nitions of normality do not always coincide with those of the individual. The appearance of the genitalia is as personal as the face, and an individual's self-perception is more important than our ideal. Level IV: Evidence obtained from multiple time series with or without the intervention, such as case studies. Dramatic results in uncontrolled trials might also be regarded as this type of evidence. Among 132 surveys distributed, 113 women completed the survey and were examined for this study (85.6%). The distribution of ages, education levels, BMI and gynecological backgrounds of the participants are given in the Table 1. Table 1 Distribution of Demographic Features and Gynecological Backgrounds of the Participants Age (year) Min-Max (Median) Mean ± Sd 19-57 (37) 36.8 ± 10.0 BMI Min-Max (Median)) Mean ± Sd 17.2-41.0(25.3) 26.2 ± 4.8 The duration of menstruation(day) Min-Max (Median) Mean ± Sd 3-15(5) 5 ± 3 The age at rst menstruation Min-Max (Median) Mean ± Sd 9-16(13) 12.9 ± 1.5 The sexual life %(n) Sexually active 77(87) Sexually inactive 23(26) No previous sexual experience 16,8(19) (37) The age at rst sexual intercourse* Min-Max (Median) Mean ± Sd 15-37 (23) 23.2 ± 4.8 Pregnant history %(n) None 35,3(40) At least once 64,6(73) Menstrual patterns**%(n) Regular cycle 90.3(93) Irregular cycle 9.8(9) Menopausal 9.7(11) Education %(n) Middle school or lower 31 (35) High school 10.6 (12) Undergraduate 42.5(48) Postgraduate (master/doctorate) 15.9(18) *The mean age at rst sexual intercourse in the 94 participants.** Ninety-two patients reported their menstrual patterns, while the other 11 (9.7%) stated they were menopausal. The majority of participants considered their genitalia normal (n = 101, 89.4%), while 12 participants (10.6%) considered them abnormal. In the normal group, only 2 participants reported that their genitalia were larger than normal, whereas all 12 of the participants in the abnormal group stated that they considered their genitalia to be large or very large. Ninety-three participants (82.3%) said the size of their genitalia was unchanged (congenital) and 20 participants (17.7%) reported that their genitalia had changed over time. Of the 14 participants who considered their genitalia large or very large, 6 (42.9%) said it was acquired and 8 (57.1%) said it was congenital. Eighty-two participants (72.6%) said they were satis ed with the appearance of their genitalia, while 31 (27.4%) were not. Five (35.7%) of the 14 participants who considered their genitalia larger than normal said they were satis ed with their appearance. In contrast, 22 (22.2%) of the participants who considered their genitalia normal were not satis ed with their appearance. Problems reported by the participants in relation to their external genitalia included physical discomfort (n = 6, 5.3%), di culty initiating sexual intercourse (n = 2, 1.8%), impact on clothing selection (n = 10, 8.9%), discomfort when wearing tight-tting clothing (n = 23, 20.4%), negative feedback from their male partner (n = 4, 3.5%), adverse effect on self-con dence (n = 20, 17.6%), adverse effect on quality of life (n = 2, 1.8%), adverse effect on sex life (n = 3, 2.7%), and adverse psychological impact (n = 4, 3.5%). In addition, 15 participants (13.3%) stated that they wanted to undergo genital aesthetic surgery. On physical examination, labia minora protrusion was detected in 45.1% (n = 51) and asymmetry in 42.5% (n = 48) of the participants. Examination ndings are shown in Table 2.
Objectives: Adolescents with intellectual disability (ID) are more likely than the general popula... more Objectives: Adolescents with intellectual disability (ID) are more likely than the general population to exhibit inappropriate and unsafe sexual behaviors and sexual behavior problems. However, few studies have investigated sexual behavior problems in these adolescents. Thus, the present study aimed to examine the types, frequency, and associated clinical features of inappropriate sexual behaviors in adolescents with ID. Material and Methods: This study included 74 adolescents diagnosed with ZE between the ages of 12-18, registered in the child and adolescent psychiatry outpatient clinic. A questionnaire form via Google documents was shared with the parents through the access networks that they could reach by contacting the parents, and the parents were asked to fill it out in order to obtain sociodemographic data and sexual behavior characteristics of the participants. Results: In our sample, the prevalence of sexual behavior problems was 35.1% and the rate of inappropriate sexual behavior in the community was 27%. Masturbation was the most commonly observed sexual behavior. Sexual behavior problems did not differ according to age and gender. However, the ID degree was significantly more severe in the group with sexual behavior problems. The rate of parents giving sexual education to their children was 18.9%, and the rate of having received sexual education by any professional for sexual behavior problems was 8.1%. Conclusion: Our results support the finding that adolescents with ID have a high risk of experiencing sexual behavior problems. In addition, it is clearly seen that there is a need for comprehensive sexual education and intervention for adolescents with ID and their families. Clinicians, psychologists, and teachers should all be aware of this.
Background: The purpose of this study to determined women’s perceptions of the vulva with the cri... more Background: The purpose of this study to determined women’s perceptions of the vulva with the criteria defined in the literature for the ideal vulva and determine their relationship with anatomical measurements in order to determine the extent to which women’s perceptions of normal align with our aesthetic standards of normality. Methods: First of all, a questionnaire was applied to all participants. The items of the data collection form were included personal information, obstetric and gynecological information, their perceptions of their external genitalia and any physical, sexual, psychological, and hygiene problems they experience. Then examination and measurements of the external genitalia were performed. Results: The majority of participants considered their genitalia normal (n=101, 89.4%), while 12 participants (10.6%) considered them abnormal. Statistical analyses showed that women’s perception of their genitalia as normal in appearance and size was associated with labia min...
The purpose of this study was to evaluate the role of WBC count, NLR, LMR, PLR, Systemic immune-i... more The purpose of this study was to evaluate the role of WBC count, NLR, LMR, PLR, Systemic immune-inflammation index (SII) [(platelet count X neutrophil count) \ lymphocyte count] and platelet count (Plt)×NLR in the differential diagnosis of basal cell carcinoma, squamous cell carcinoma, and malignant melanoma and to determine the effect of tumor type, prediction of lymph node metastasis at initial diagnosis and location on these inflammatory markers. Material and Method: Patients who underwent surgery for basal cell carcinoma, squamous cell carcinoma, or malignant melanoma were retrospectively screened. NLR, LMR, PLR, SII and Plt×NLR were calculated. Relationships between tumor type, prediction of lymph node metastasis at initial diagnosis, tumor localization and the inflammatory and hematological parameters of interest were investigated. Tumor location was classified as head and neck and others. Results: A total of 257 patients were included in the study. No statistically significant differences in WBC, NLR, PLR, LMR, SII or Plt×NLR were detected according to tumor location. The patients with squamous cell carcinoma had higher NLR, PRL, SII and Plt×NLR values than those with basal cell carcinoma. The risk of lymph node metastasis at the time of initial diagnosis was 10.3 times higher in patients with PLR levels of 180.7 and higher. The risk of lymph node metastasis detected at initial diagnosis was 8.9 times higher in patients with Plt×NLR of 747 and higher. The risk of lymph node metastasis detected at initial diagnosis was 7.1 times higher in patients with SII of 414 and higher. Conclusion: Inflammatory markers seem to be useful in the differential diagnosis of skin cancers and determined the risk of lymph node metastasis. However, it does not differ according to tumor localization.
Aim: The purpose of this study was to evaluate the role of WBC count, NLR, LMR, PLR, Systemic imm... more Aim: The purpose of this study was to evaluate the role of WBC count, NLR, LMR, PLR, Systemic immune-inflammation index (SII) [(platelet count X neutrophil count) \ lymphocyte count] and platelet count (Plt)×NLR in the differential diagnosis of basal cell carcinoma, squamous cell carcinoma, and malignant melanoma and to determine the effect of tumor type, prediction of lymph node metastasis at initial diagnosis and location on these inflammatory markers. Material and Method: Patients who underwent surgery for basal cell carcinoma, squamous cell carcinoma, or malignant melanoma were retrospectively screened. NLR, LMR, PLR, SII and Plt×NLR were calculated. Relationships between tumor type, prediction of lymph node metastasis at initial diagnosis, tumor localization and the inflammatory and hematological parameters of interest were investigated. Tumor location was classified as head and neck and others. Results: A total of 257 patients were included in the study. No statistically signi...
Background: Cervical cancer is one of the most common cancers in women and causes death. Revealin... more Background: Cervical cancer is one of the most common cancers in women and causes death. Revealing the distribution of HPV prevalence and types in cervical cancer remains important for both treatment and vaccination strategies. The goal of this study is to determine the HPV DNA subtypes of women who are positive for Human Papilloma Virus (HPV) screening, and to evaluate their sociodemographic characteristics and cervical smear results. Methods: The study was conducted on 215 women who were directed to Sivas Cumhuriyet University Obstetry and Gynocology outpatient clinic by her gynocologists or family physicians between 2015-2018 years. A questionnary containing datas of patients about age, education levels and jobs of both spouses, smoking status, obstetric history and age of first sexual intercourse was filled out by the researcher. The data were analysed with SPSS (vers 23.0) program and significance level was taken as 0.05. Results: The most prevalent HPV types were type 16 and c...
Objective: Although the pregnancy period is a physiological process, it can disrupt the sleep pat... more Objective: Although the pregnancy period is a physiological process, it can disrupt the sleep pattern and quality with some changes it causes. In this study, it was aimed to determine sleep quality, affecting factors and sleep problems, if any, in pregnant women who applied to our outpatient clinic for follow-up. Materials and Methods: This study, which was designed in a descriptive style, was conducted on 256 pregnant women who applied to the outpatient clinic. The data form included personal information, factors affecting sleep quality, sleep problems and Pittsburg Sleep Quality Index. In addition to descriptive statistics, Mann-Whitney U and Kruskal Wallis tests were used to evaluate the data uploaded to the SPSS program. The error level was set to 0.05. Results: The mean age of the pregnant women was 28.55. It was observed that the mean total PUKI score was 6.27±3.94 (0-18) and the mean sleep duration was 7.5 hours (3-14). Sleep quality was poor in 49.6% of the pregnant women. I...
Objective: To investigate markers of carotid atherosclerosis and oxidized low density lipoprotein... more Objective: To investigate markers of carotid atherosclerosis and oxidized low density lipoprotein (OxLDL) levels in patients with Familial Mediterranean Fever (FMF) who have no risk factors for cardiovascular disease. Method: It was included 44 patients (25 F/19 M; mean age: 33.5±7.5) with FMF in attack free period and gender and age matched 44 healthy subjects (25 F/19 M; mean age: 33.4±7.0). The patients with clinical coronary artery disease, chronic renal disease, diabetes mellitus, hypertension, history of myocardial infarction, angina pectoris, cerebrovascular disease, dyslipidemia, metabolic syndrome, active infection, those in postmenopausal period, and those using anti-lipid drugs were excluded. Carotid artery intima-media thickness (C-IMT) was measured and investigated atherosclerotic plaques in the carotids by using doppler ultrasound. Serum lipid and OxLDL levels were also assessed. Data were analyzed with the SPSS program and p
Objective: There are few studies in the literature on somatic symptoms and related disorders (SSR... more Objective: There are few studies in the literature on somatic symptoms and related disorders (SSRD) in children. The aim of this study is to investigate emotional and behavioral difficulties, self-esteem, psychopathology, and clinical characteristics in children with somatic symptoms. Method: This study included 44 children with recurrent and distressing somatic complaint(s) and 49 healthy children. The diagnosis of SSRD was evaluated in detail according to DSM-5 criteria. Self-esteem, emotional and behavioral difficulties, and somatization were assessed using the Rosenberg Self-Esteem Scale (RSES), Strengths and Difficulties Questionnaire (SDQ), and Children's Somatization Inventory (CSI-24), respectively. Results: Children with somatization had significantly greater rates of having at least one comorbid mental disorder, emotional symptoms scores, and peer relationship problems. On the other hand, these children's prosocial behavior scores (Strengths Score), self-esteem sco...
Background: Depression is a major public health problem in all ages. Besides other chronic physic... more Background: Depression is a major public health problem in all ages. Besides other chronic physical diseases, it is one of the most common psychiatric disorders observed in the elderly. In this study, it was aimed to determine the prevalence of depressive symptoms and related factors and to draw attention to occult suicide probability in elderly people without significant disabling disease. Methods: Individuals aged 65 and over, who were randomly selected from a family healthcare centre, were enrolled into the study. Geriatric Depression Scale (GDS) was used to assess prevalence of depression and Suicide Probability Scale (SPS) for risk of suicide. Results: There were 323 elderly (F/M: 150/173). Mean age was 73.3 AE 6.1 years. The majority had chronic physical illnesses (77.7%). Mean GDS and SPS scores were 11.07 AE 4.6 and 62.91 AE 8.24, respectively. Prevalence of depression was 27.6%. In multivariable logistic regression analysis, living without a spouse (P = 0.047, Exp(B) = 1.744, 95% CI = 1.008-3.01), dissatisfaction with life (P < 0.001, Exp(B) = 5.327, 95% CI = 3.02-9.36) and having no leisure time activity (P = 0.047, Exp(B) = 1.846, 95% CI = 1.009-3.37) were found to be the independent predictors of presence of depression, as indicated by GDS. In logistic regression analysis, dissatisfaction with life (P < 0.001, Exp(B) = 2.631, 95% CI = 1.53-4.50) was found to be an independent predictor of high SPS scores. Conclusion: In elderly individuals without overt disabling disease, dissatisfaction with life, absence of leisure time activities, and a life without a partner seem to significantly increase the likelihood of overt depression. On the other hand, there is occult increase in suicide risk in the presence of dissatisfaction with their lives in the elderly.
Objective: Anaphylaxis is under-recognized and undertreated by physicians, indicating critical kn... more Objective: Anaphylaxis is under-recognized and undertreated by physicians, indicating critical knowledge gaps. This study aimed to assess the knowledge levels of anaphylaxis among family physicians (FPs) as they are the primary first-line healthcare providers and identify the factors influencing their knowledge levels. Materials and Methods: A cross-sectional study using an internet-based Google Forms questionnaire was conducted among voluntary FPs in Sivas, Turkey. Demographic features, including age, years in practice, and career position, and knowledge related to the diagnosis and management of anaphylaxis in children were assessed. Results: A total of 140 FPs participated in the survey (34 [24.3%] general practitioners [GPs], 20 [14.3%] contracted family physicians [CFPs], 74 [52.9%] residents in training [RITs], and 12 [8.6%] specialists). The number of participants who correctly answered all questions regarding diagnosis, acute treatment, and epinephrine auto-injector use was 11 (7.9%), 52 (37.4%), and 27 (19.3%), respectively. In diagnosing anaphylaxis, 100 (72.5%) participants were unaware that anaphylaxis can occur without skin manifestations, and only 48 (34.8%) identified gastrointestinal symptoms as a possible anaphylaxis presentation. RITs (11, 14.9%) and specialists (2, 16.7%) had better performance on the questionnaire, with higher proportions of participants who answered all questions correctly, compared to GPs (2, 5.9%) and CFPs (1, 5.0%). Attendance at an educational activity in the last year was the only independent factor associated with answering all questionnaire items correctly. Conclusion: There is a need to improve anaphylaxis recognition and management among all FPs regardless of their career position and work experience, underlining the importance of regular and updated educational interventions.
Archives of Gynecology and Obstetrics, Feb 18, 2023
Background: The purpose of this study to determined women's perceptions of the vulva with the cri... more Background: The purpose of this study to determined women's perceptions of the vulva with the criteria de ned in the literature for the ideal vulva and determine their relationship with anatomical measurements in order to determine the extent to which women's perceptions of normal align with our aesthetic standards of normality. Methods: First of all, a questionnaire was applied to all participants. The items of the data collection form were included personal information, obstetric and gynecological information, their perceptions of their external genitalia and any physical, sexual, psychological, and hygiene problems they experience. Then examination and measurements of the external genitalia were performed. Results: The majority of participants considered their genitalia normal (n=101, 89.4%), while 12 participants (10.6%) considered them abnormal. Statistical analyses showed that women's perception of their genitalia as normal in appearance and size was associated with labia minora asymmetry (p=0.023 and p=0.006, respectively) and hyperpigmentation (p=0.010 and p=0.047, respectively) but not with labia minora measurements or protrusion (p>0.05) Conclusions : Although there is a tendency in the eld of aesthetic surgery to de ne ideals and aesthetic standards for all parts of the body, our de nitions of normality do not always coincide with those of the individual. The appearance of the genitalia is as personal as the face, and an individual's self-perception is more important than our ideal. Level IV: Evidence obtained from multiple time series with or without the intervention, such as case studies. Dramatic results in uncontrolled trials might also be regarded as this type of evidence. Among 132 surveys distributed, 113 women completed the survey and were examined for this study (85.6%). The distribution of ages, education levels, BMI and gynecological backgrounds of the participants are given in the Table 1. Table 1 Distribution of Demographic Features and Gynecological Backgrounds of the Participants Age (year) Min-Max (Median) Mean ± Sd 19-57 (37) 36.8 ± 10.0 BMI Min-Max (Median)) Mean ± Sd 17.2-41.0(25.3) 26.2 ± 4.8 The duration of menstruation(day) Min-Max (Median) Mean ± Sd 3-15(5) 5 ± 3 The age at rst menstruation Min-Max (Median) Mean ± Sd 9-16(13) 12.9 ± 1.5 The sexual life %(n) Sexually active 77(87) Sexually inactive 23(26) No previous sexual experience 16,8(19) (37) The age at rst sexual intercourse* Min-Max (Median) Mean ± Sd 15-37 (23) 23.2 ± 4.8 Pregnant history %(n) None 35,3(40) At least once 64,6(73) Menstrual patterns**%(n) Regular cycle 90.3(93) Irregular cycle 9.8(9) Menopausal 9.7(11) Education %(n) Middle school or lower 31 (35) High school 10.6 (12) Undergraduate 42.5(48) Postgraduate (master/doctorate) 15.9(18) *The mean age at rst sexual intercourse in the 94 participants.** Ninety-two patients reported their menstrual patterns, while the other 11 (9.7%) stated they were menopausal. The majority of participants considered their genitalia normal (n = 101, 89.4%), while 12 participants (10.6%) considered them abnormal. In the normal group, only 2 participants reported that their genitalia were larger than normal, whereas all 12 of the participants in the abnormal group stated that they considered their genitalia to be large or very large. Ninety-three participants (82.3%) said the size of their genitalia was unchanged (congenital) and 20 participants (17.7%) reported that their genitalia had changed over time. Of the 14 participants who considered their genitalia large or very large, 6 (42.9%) said it was acquired and 8 (57.1%) said it was congenital. Eighty-two participants (72.6%) said they were satis ed with the appearance of their genitalia, while 31 (27.4%) were not. Five (35.7%) of the 14 participants who considered their genitalia larger than normal said they were satis ed with their appearance. In contrast, 22 (22.2%) of the participants who considered their genitalia normal were not satis ed with their appearance. Problems reported by the participants in relation to their external genitalia included physical discomfort (n = 6, 5.3%), di culty initiating sexual intercourse (n = 2, 1.8%), impact on clothing selection (n = 10, 8.9%), discomfort when wearing tight-tting clothing (n = 23, 20.4%), negative feedback from their male partner (n = 4, 3.5%), adverse effect on self-con dence (n = 20, 17.6%), adverse effect on quality of life (n = 2, 1.8%), adverse effect on sex life (n = 3, 2.7%), and adverse psychological impact (n = 4, 3.5%). In addition, 15 participants (13.3%) stated that they wanted to undergo genital aesthetic surgery. On physical examination, labia minora protrusion was detected in 45.1% (n = 51) and asymmetry in 42.5% (n = 48) of the participants. Examination ndings are shown in Table 2.
Objectives: Adolescents with intellectual disability (ID) are more likely than the general popula... more Objectives: Adolescents with intellectual disability (ID) are more likely than the general population to exhibit inappropriate and unsafe sexual behaviors and sexual behavior problems. However, few studies have investigated sexual behavior problems in these adolescents. Thus, the present study aimed to examine the types, frequency, and associated clinical features of inappropriate sexual behaviors in adolescents with ID. Material and Methods: This study included 74 adolescents diagnosed with ZE between the ages of 12-18, registered in the child and adolescent psychiatry outpatient clinic. A questionnaire form via Google documents was shared with the parents through the access networks that they could reach by contacting the parents, and the parents were asked to fill it out in order to obtain sociodemographic data and sexual behavior characteristics of the participants. Results: In our sample, the prevalence of sexual behavior problems was 35.1% and the rate of inappropriate sexual behavior in the community was 27%. Masturbation was the most commonly observed sexual behavior. Sexual behavior problems did not differ according to age and gender. However, the ID degree was significantly more severe in the group with sexual behavior problems. The rate of parents giving sexual education to their children was 18.9%, and the rate of having received sexual education by any professional for sexual behavior problems was 8.1%. Conclusion: Our results support the finding that adolescents with ID have a high risk of experiencing sexual behavior problems. In addition, it is clearly seen that there is a need for comprehensive sexual education and intervention for adolescents with ID and their families. Clinicians, psychologists, and teachers should all be aware of this.
Background: The purpose of this study to determined women’s perceptions of the vulva with the cri... more Background: The purpose of this study to determined women’s perceptions of the vulva with the criteria defined in the literature for the ideal vulva and determine their relationship with anatomical measurements in order to determine the extent to which women’s perceptions of normal align with our aesthetic standards of normality. Methods: First of all, a questionnaire was applied to all participants. The items of the data collection form were included personal information, obstetric and gynecological information, their perceptions of their external genitalia and any physical, sexual, psychological, and hygiene problems they experience. Then examination and measurements of the external genitalia were performed. Results: The majority of participants considered their genitalia normal (n=101, 89.4%), while 12 participants (10.6%) considered them abnormal. Statistical analyses showed that women’s perception of their genitalia as normal in appearance and size was associated with labia min...
The purpose of this study was to evaluate the role of WBC count, NLR, LMR, PLR, Systemic immune-i... more The purpose of this study was to evaluate the role of WBC count, NLR, LMR, PLR, Systemic immune-inflammation index (SII) [(platelet count X neutrophil count) \ lymphocyte count] and platelet count (Plt)×NLR in the differential diagnosis of basal cell carcinoma, squamous cell carcinoma, and malignant melanoma and to determine the effect of tumor type, prediction of lymph node metastasis at initial diagnosis and location on these inflammatory markers. Material and Method: Patients who underwent surgery for basal cell carcinoma, squamous cell carcinoma, or malignant melanoma were retrospectively screened. NLR, LMR, PLR, SII and Plt×NLR were calculated. Relationships between tumor type, prediction of lymph node metastasis at initial diagnosis, tumor localization and the inflammatory and hematological parameters of interest were investigated. Tumor location was classified as head and neck and others. Results: A total of 257 patients were included in the study. No statistically significant differences in WBC, NLR, PLR, LMR, SII or Plt×NLR were detected according to tumor location. The patients with squamous cell carcinoma had higher NLR, PRL, SII and Plt×NLR values than those with basal cell carcinoma. The risk of lymph node metastasis at the time of initial diagnosis was 10.3 times higher in patients with PLR levels of 180.7 and higher. The risk of lymph node metastasis detected at initial diagnosis was 8.9 times higher in patients with Plt×NLR of 747 and higher. The risk of lymph node metastasis detected at initial diagnosis was 7.1 times higher in patients with SII of 414 and higher. Conclusion: Inflammatory markers seem to be useful in the differential diagnosis of skin cancers and determined the risk of lymph node metastasis. However, it does not differ according to tumor localization.
Aim: The purpose of this study was to evaluate the role of WBC count, NLR, LMR, PLR, Systemic imm... more Aim: The purpose of this study was to evaluate the role of WBC count, NLR, LMR, PLR, Systemic immune-inflammation index (SII) [(platelet count X neutrophil count) \ lymphocyte count] and platelet count (Plt)×NLR in the differential diagnosis of basal cell carcinoma, squamous cell carcinoma, and malignant melanoma and to determine the effect of tumor type, prediction of lymph node metastasis at initial diagnosis and location on these inflammatory markers. Material and Method: Patients who underwent surgery for basal cell carcinoma, squamous cell carcinoma, or malignant melanoma were retrospectively screened. NLR, LMR, PLR, SII and Plt×NLR were calculated. Relationships between tumor type, prediction of lymph node metastasis at initial diagnosis, tumor localization and the inflammatory and hematological parameters of interest were investigated. Tumor location was classified as head and neck and others. Results: A total of 257 patients were included in the study. No statistically signi...
Background: Cervical cancer is one of the most common cancers in women and causes death. Revealin... more Background: Cervical cancer is one of the most common cancers in women and causes death. Revealing the distribution of HPV prevalence and types in cervical cancer remains important for both treatment and vaccination strategies. The goal of this study is to determine the HPV DNA subtypes of women who are positive for Human Papilloma Virus (HPV) screening, and to evaluate their sociodemographic characteristics and cervical smear results. Methods: The study was conducted on 215 women who were directed to Sivas Cumhuriyet University Obstetry and Gynocology outpatient clinic by her gynocologists or family physicians between 2015-2018 years. A questionnary containing datas of patients about age, education levels and jobs of both spouses, smoking status, obstetric history and age of first sexual intercourse was filled out by the researcher. The data were analysed with SPSS (vers 23.0) program and significance level was taken as 0.05. Results: The most prevalent HPV types were type 16 and c...
Objective: Although the pregnancy period is a physiological process, it can disrupt the sleep pat... more Objective: Although the pregnancy period is a physiological process, it can disrupt the sleep pattern and quality with some changes it causes. In this study, it was aimed to determine sleep quality, affecting factors and sleep problems, if any, in pregnant women who applied to our outpatient clinic for follow-up. Materials and Methods: This study, which was designed in a descriptive style, was conducted on 256 pregnant women who applied to the outpatient clinic. The data form included personal information, factors affecting sleep quality, sleep problems and Pittsburg Sleep Quality Index. In addition to descriptive statistics, Mann-Whitney U and Kruskal Wallis tests were used to evaluate the data uploaded to the SPSS program. The error level was set to 0.05. Results: The mean age of the pregnant women was 28.55. It was observed that the mean total PUKI score was 6.27±3.94 (0-18) and the mean sleep duration was 7.5 hours (3-14). Sleep quality was poor in 49.6% of the pregnant women. I...
Objective: To investigate markers of carotid atherosclerosis and oxidized low density lipoprotein... more Objective: To investigate markers of carotid atherosclerosis and oxidized low density lipoprotein (OxLDL) levels in patients with Familial Mediterranean Fever (FMF) who have no risk factors for cardiovascular disease. Method: It was included 44 patients (25 F/19 M; mean age: 33.5±7.5) with FMF in attack free period and gender and age matched 44 healthy subjects (25 F/19 M; mean age: 33.4±7.0). The patients with clinical coronary artery disease, chronic renal disease, diabetes mellitus, hypertension, history of myocardial infarction, angina pectoris, cerebrovascular disease, dyslipidemia, metabolic syndrome, active infection, those in postmenopausal period, and those using anti-lipid drugs were excluded. Carotid artery intima-media thickness (C-IMT) was measured and investigated atherosclerotic plaques in the carotids by using doppler ultrasound. Serum lipid and OxLDL levels were also assessed. Data were analyzed with the SPSS program and p
Objective: There are few studies in the literature on somatic symptoms and related disorders (SSR... more Objective: There are few studies in the literature on somatic symptoms and related disorders (SSRD) in children. The aim of this study is to investigate emotional and behavioral difficulties, self-esteem, psychopathology, and clinical characteristics in children with somatic symptoms. Method: This study included 44 children with recurrent and distressing somatic complaint(s) and 49 healthy children. The diagnosis of SSRD was evaluated in detail according to DSM-5 criteria. Self-esteem, emotional and behavioral difficulties, and somatization were assessed using the Rosenberg Self-Esteem Scale (RSES), Strengths and Difficulties Questionnaire (SDQ), and Children's Somatization Inventory (CSI-24), respectively. Results: Children with somatization had significantly greater rates of having at least one comorbid mental disorder, emotional symptoms scores, and peer relationship problems. On the other hand, these children's prosocial behavior scores (Strengths Score), self-esteem sco...
Background: Depression is a major public health problem in all ages. Besides other chronic physic... more Background: Depression is a major public health problem in all ages. Besides other chronic physical diseases, it is one of the most common psychiatric disorders observed in the elderly. In this study, it was aimed to determine the prevalence of depressive symptoms and related factors and to draw attention to occult suicide probability in elderly people without significant disabling disease. Methods: Individuals aged 65 and over, who were randomly selected from a family healthcare centre, were enrolled into the study. Geriatric Depression Scale (GDS) was used to assess prevalence of depression and Suicide Probability Scale (SPS) for risk of suicide. Results: There were 323 elderly (F/M: 150/173). Mean age was 73.3 AE 6.1 years. The majority had chronic physical illnesses (77.7%). Mean GDS and SPS scores were 11.07 AE 4.6 and 62.91 AE 8.24, respectively. Prevalence of depression was 27.6%. In multivariable logistic regression analysis, living without a spouse (P = 0.047, Exp(B) = 1.744, 95% CI = 1.008-3.01), dissatisfaction with life (P < 0.001, Exp(B) = 5.327, 95% CI = 3.02-9.36) and having no leisure time activity (P = 0.047, Exp(B) = 1.846, 95% CI = 1.009-3.37) were found to be the independent predictors of presence of depression, as indicated by GDS. In logistic regression analysis, dissatisfaction with life (P < 0.001, Exp(B) = 2.631, 95% CI = 1.53-4.50) was found to be an independent predictor of high SPS scores. Conclusion: In elderly individuals without overt disabling disease, dissatisfaction with life, absence of leisure time activities, and a life without a partner seem to significantly increase the likelihood of overt depression. On the other hand, there is occult increase in suicide risk in the presence of dissatisfaction with their lives in the elderly.
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