Papers by Dimitrios Kasselimis
Age-related memory changes are highly varied and heterogeneous. The study examined the rate of de... more Age-related memory changes are highly varied and heterogeneous. The study examined the rate of decline in verbal episodic memory as a function of education level, auditory attention span and verbal working memory capacity, and diagnosis of amnestic mild cognitive impairment (a-MCI). Data were available on a community sample of 653 adults aged 17-86 years and 70 patients with a-MCI recruited from eight broad geographic areas in Greece and Cyprus. Measures of auditory attention span and working memory capacity (digits forward and backward) and verbal episodic memory (Auditory Verbal Learning Test [AVLT]) were used. Moderated mediation regressions on data from the community sample did not reveal significant effects of education level on the rate of age-related decline in AVLT indices. The presence of a-MCI was a significant moderator of the direct effect of Age on both immediate and delayed episodic memory indices. The rate of age-related decline in verbal episodic memory is normally mediated by working memory capacity. Moreover, in persons who display poor episodic memory capacity (a-MCI group), age-related memory decline is expected to advance more rapidly for those who also display relatively poor verbal working memory capacity.
Procedia - Social and Behavioral Sciences, 2013
Frontiers in Psychology, 2014
ABSTRACT
Journal of Neurolinguistics, 2016
International Encyclopedia of the Social & Behavioral Sciences, 2015
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, Jan 7, 2016
Cognitive deficits affecting memory, attention, speed of information processing and executive fun... more Cognitive deficits affecting memory, attention, speed of information processing and executive functions are common in multiple sclerosis (MS). In this study we examine the possibility of discrete pattern of neuropsychological deficits of MS subtypes. 28 patients (13 RRMS, 6 CIS, and 9 SPMS) were assessed with a comprehensive neuropsycholgical battery. Results indicate that only the SPMS group demonstrates memory and executive impairment. This finding indicates possible differentiation of the three subtypes in terms of neuropsychological profiles. Psychiatric aspects of MS are also briefly discussed.
Procedia - Social and Behavioral Sciences, 2013
Dementia and Geriatric Cognitive Disorders
The present article investigates agrammatism from a neurological/neuropsychological perspective. ... more The present article investigates agrammatism from a neurological/neuropsychological perspective. Agrammatism was originally defined as ‘telegraphic’ speech output characterizing nonfluent types of aphasia. During the last five decades, it has been well documented that agrammatic patients frequently present impaired comprehension of syntactically complex sentences, a phenomenon known as ‘asyntactic comprehension.’ Although agrammatism was traditionally linked to frontal lesion loci, such as Broca's area, contemporary lesion and brain-imaging studies depict a widely distributed neural network, consisting of frontal, temporal, and parietal cortical regions, associated with syntactic processing and agrammatic performance. Possible relationships between syntactic comprehension and working memory are also discussed.
International Encyclopedia of the Social & Behavioral Sciences, 2015
Frontiers in Psychology, 2014
ABSTRACT
Procedia - Social and Behavioral Sciences, 2013
Archives of Neuroscience, 2015
Background: Parkinson's disease (PD) is a neurodegenerative disorder characterized by pervasive m... more Background: Parkinson's disease (PD) is a neurodegenerative disorder characterized by pervasive motor deficits, often accompanied by specific cognitive impairments, most prominently executive dysfunctions. However, it is often hard to determine whether the impaired performance of patients with PD on executive tests is the result of an executive dysfunction or whether it is due to motor difficulties. Objectives: The present study aimed to examine the relationship between cognitive inflexibility, an executive dysfunction consistently found in PD, and motor deficiencies in patients with PD using derived scores, from a common executive function test named trail making test (TMT). Patients and Methods: Fifty patients with PD and 50 demographically matched controls underwent neuropsychological examination which included TMT, part A and part B. Performance on each task was assessed and the following derived scores TMT B/A, TMT B-A/A, and TMT B-A were calculated and compared. Results: Mann-Whitney tests revealed significant group differences for the mean TMT A (P = 0.006) and TMT B (P = 0.000), which were both higher in the PD group, relative to controls. In addition, significant differences were found for one TMT product score (TMT B-A).
Journal of the International Neuropsychological Society : JINS, 2014
Age-related memory changes are highly varied and heterogeneous. The study examined the rate of de... more Age-related memory changes are highly varied and heterogeneous. The study examined the rate of decline in verbal episodic memory as a function of education level, auditory attention span and verbal working memory capacity, and diagnosis of amnestic mild cognitive impairment (a-MCI). Data were available on a community sample of 653 adults aged 17-86 years and 70 patients with a-MCI recruited from eight broad geographic areas in Greece and Cyprus. Measures of auditory attention span and working memory capacity (digits forward and backward) and verbal episodic memory (Auditory Verbal Learning Test [AVLT]) were used. Moderated mediation regressions on data from the community sample did not reveal significant effects of education level on the rate of age-related decline in AVLT indices. The presence of a-MCI was a significant moderator of the direct effect of Age on both immediate and delayed episodic memory indices. The rate of age-related decline in verbal episodic memory is normally m...
Child Neuropsychology, 2008
Procedia - Social and Behavioral Sciences, 2012
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Papers by Dimitrios Kasselimis