Astrocytic PERK Deficiency Drives Prefrontal Circuit Dysfunction and Depressive-Like Behaviors.
Kai Chen, Riya Gupta, Yosuke M Morizawa et al.
...+ water).
Fear conditioning: Fear conditioning was conducted in a conditioning chamber (Maze Engineers) with ANY‐maze recording. On training day, mice were habituated for 2 min, followed by three...
When Familiar Faces Feel Better: A Framework for Social Neurocognitive Aging in a Rat Model.
Subhadeep Dutta Gupta, Jeffrey M Long, Peter R Rapp
...being placed in a three-chamber apparatus for social behavioral testing. The custom apparatus (Maze Engineers) featured three adjacent compartments (40 × 80 × 40 cm; L × W × H) divided by walls with...
Acetyl-carnitine improves hyperactivity and learning deficits in <i>KAT6A</i> haploinsufficient mice.
Samantha Eccles, Hannah K Vanyai, Maria I Bergamasco et al.
...to seek and enter a target hole. The operator was located behind a curtain. The Barnes maze (MazeEngineers) was comprised of a white circular platform 92 cm in diameter and 95 cm high with 20 circular...
MCD enzyme deficiency drives early mortality and multiorgan metabolic disruption in Dahl salt-sensitive rats.
Olha Kravtsova, Yifan Tan, Vladislav Levchenko et al.
...was assessed in male 7-week-old SSMlycd+/+ and SSMlycd+/- rats using a motor-driven treadmill (Maze Engineers, Skokie, IL). All animals underwent a standardized acclimation and testing protocol to ensure...
APP-mediated intracellular signaling rescues sleep impairment and blood-brain barrier leakage in Alzheimer's disease mouse model.
Clémentine Puech, Anjana Sadanand, Neil Coleman et al.
...(NOR) and Elevated Plus Maze (EPM) tests. Maze equipment for EPM and NOR was obtained from Maze Engineers (Cambridge, MA, USA). The recordings for EPM and NOR were captured from an overhead vantagepoint...
The E-Protein Daughterless Regulates Olfactory Learning of Adult Drosophila melanogaster.
Laura Tamberg, Carl Sander Kiir, Jürgen Tuvikene et al.
...paper previously soaked with deionized water and dried. The vial was attached to a T-maze (Maze Engineers) and left to rest while air flow was applied for 30 s. Then, first odor presented. After 2 min,...
Genetic depletion of the early autophagy protein ATG13 impairs mitochondrial energy metabolism, augments oxidative stress, induces the polarization of macrophages to the M1 inflammatory mode, and compromises myelin integrity in skeletal muscle.
Mubaraq A Toriola, Emma Timlin, Sarojini Bulbule et al.
...and NTg mice aged 10–12 weeks (n = 6) were tested using a rectangular grid attached to a console (Maze Engineers) that records grip force (Newton) over time, displayed via Grip TestUI (version 1.0.0.0)...
Pathological gain-of-function human variants in the GRIK2 kainate receptor gene cause wide-ranging behavioral dysfunction and seizures in mouse models.
Brynna T Webb, Hieu Trinh, Emily A Breach et al.
...Differences were considered significant if p < 0.05.
T-maze test
Automated T-Maze testing (MazeEngineers, Skokie, IL, USA) was performed to assess learning and working memory as described. GluK2(A657T)...
Karin N. Westlund, Bingye Xue, Sabrina L. McIlwrath
...with high, protective walls (30 cm high) at the perimeter, and two open ones, lacking barriers (Maze Engineers, Skokie, IL, USA). The assay was started by placing each animal on the runway of an open...
Development of visual-stimulus reversal learning-memory in mice is dependent on social interaction.
Sarah Wicki, Annika Canziani, Giulia Poggi et al.
...a grey PVC chamber (30.5 x 20.5 x 17.8 cm, L x W x H; Attentional Set Shifting (IDED) Chamber, Maze Engineers) divided into one starting compartment and two stimulus compartments. The starting compartment...
0.33<i>g</i> mitigates muscle atrophy while 0.67<i>g</i> preserves muscle function and myofiber type composition in mice during spaceflight.
Ryosuke Tsuji, Ryo Fujita, Takuto Hayashi et al.
grip strength was tested before and immediately following live animal return using a 50-N capacity grip strength meter (Conduct Science, Skokie, IL, USA). The person performing the grip strength testing was blinded to the experimental conditions during fl
2025 Korean Society of Environmental Biology (KOSEB) Annual Conference Proceedings2025
Analysis of Behavioral Characteristics by Population Size in Ornamental Fish: A Video Tracking-Based Experimental Study.
Jong-Mo Seo, Seung-Bin Heo, Hyun-Bin Cho
촬영된 영상은 20분씩 분할하여 24개 영상이 ConductVision Tracking and Analysis Software (Conduct Science Inc.) 를 사용하여 분석되었으며, 각 개체의 좌표 기반 이동 데이터를 추출하였다.
Manual
aging and disease2025
The Impact of Rosemary and Ginger Extracts on Aging and Healthspan in Drosophila.
Ricardo Aparicio, Anna M Salazar, Edward T Schmid et al.
...Training
Aversion training was performed as described in using a system from MazeEngineers (Conduct Science). Briefly, flies were exposed to a neutral odor (3-octanol) by air pump in a training chamber for...
Clearance of intracranial debris by ultrasound reduces inflammation and improves outcomes in hemorrhagic stroke models.
Matine M Azadian, Sepideh Kiani Shabestari, Arjun Rajan et al.
Digital Grip Strength Meter (Maze Engineers)
npj Parkinson's Disease2025
Depending on intensity, exercise improved or worsened pathology in a model of prodromal Parkinson's disease.
Leonie Baldauf, Malte Feja, Milos Stanojlovic et al.
...regimen
Mice were trained for running on a 5-lane motorized treadmill (Model 60A SM 400-LS-Z, maze engineers, USA). The industrial made treadmill needed to be optimized by removing pointed and sharp corners...
Experimental Galactose-1-Phosphate Uridylyltransferase (GALT) mRNA Therapy Improves Motor-Related Phenotypes in a Mouse Model of Classic Galactosemia-A Pilot Study.
Olivia Bellagamba, Aaron J Guo, Xinhua Yan et al.
...rotarod and accompanying software (Conductor Science SA102) used in this study was purchased from Maze Engineers (Skokie, IL, USA). Mice first completed a training session on the rotarod where they would walk...
MICU2 controls mitochondrial calcium signaling and migration in neurons during development.
Elena Berezhnaya, Benjamín Cartes-Saavedra, Raghavendra Singh et al.
...as described before. Sensorimotor coordination and balance were assessed using a Rotarod device (Maze Engineers). Following training, 11-month-old animals were tested during 5 trials, 120 s each, on a rotating...
Representations of stimulus features in the ventral hippocampus.
Jeremy S Biane, Max A Ladow, Austin Fan et al.
...5" full length of each arm type, 2" arm width, 7" tall closed arms, with 0.5" tall/wide ledges on the open arms made by Maze Engineers, Skokie, IL), with 450 light lux centered over the maze.
Longitudinal characterization reveals behavioral impairments in aged APP knock in mouse models
Lisa Blackmer-Raynolds, Lyndsey D Lipson, Isabel Fraccaroli et al.
...assess spatial learning and memory. Testing occurred on a 92 cm diameter, 20 hole, Barnes maze (MazeEngineers) over a 6-day period, with one habituation trial, five 3-minute training trials, and a 72-hour...
22 and 50 kHz rat ultrasonic vocalization playback reveals sex differences in behavior and cFos in brain regions associated with affective processing.
Sydney M Bonauto, Kaya A Patel, Jennifer A Honeycutt
...transported to the testing room in a clean transport cage and placed in the corner of a 100 x 100 cm x 40 cm open field (Maze Engineers, Skokie, IL). Behavior was recorded for the entire session.
Pretreatment of Mice with 830 nm Light Enhances Endurance During Acute Exercise.
Nashwa Cheema, Namrata Ghag, Linh Pham et al.
...acclimatized to the treadmill for 3 days. Briefly, they were placed on an unmoving treadmill (Maze Engineers, Skokie, IL, USA) for 1–3 min and then allowed to run at a speed of 10 m/min. To test endurance...
Moderate Chronic Treadmill Exercise Slows Dopaminergic Neuron Loss in a Rat Model of Parkinson's Disease and Alters RNA Content of Circulating Plasma Exosomes
Bruce A Citron, Maynard Guzman, Bobak Shapdoor et al.
Molecular Neurobiology2025
Chronic Alcohol Drinking Impairs Recognition Memory And Insulin-Associated Genes In The Medial Prefrontal Cortex.
Bryan Cruz, Michela Palmisano, Alex Hiroto et al.
...mounted on a fixed stand. The floors were gray, and the walls were made of clear plexiglass (Maze Engineers®, Skokie, IL). RAM testing included three phases, (1) acclimation to chocolate-flavored reward...
Protective exercise responses in the dentate gyrus of Alzheimer's disease mouse model revealed with single-nucleus RNA-sequencing.
Joana F da Rocha, Michelle L Lance, Renhao Luo et al.
Mice were placed into a conditioning chamber (17 cm long x 17 cm wide x 25 cm high, Maze Engineers, Skokie, IL) with Plexiglas sidewalls and a floor of stainless-steel bars.
Therapeutic Treatment With OLX-07010 Inhibited Tau Aggregation and Ameliorated Motor Deficits in an Aged Mouse Model of Tauopathy
E J Davidowitz, P Lopez, D Patel et al.
...precision, recovery, carryover, and stability.
Motor Behavior
Motor function was assayed with MazeEngineers 6‐Lane rotarod for mice (Deacon ; Koppel et al. ). All mice were acclimated 2 weeks prior to the...
Central biogenic amine deficiency with concomitant exploratory behavioral deficits in Dnajc12 knock-out mice
Isaac Bul Deng, Jordan Follett, Jesse D. Fox et al.
...grid by the mouse is recorded by the force sensor and analyzed with the Grip Strength software (Maze Engineers, Skokie, IL, USA). Balance beams were applied to examine the sensorineural balance and...
Behavioral Physiology of the CNTNAP2 Knockout Mouse
Tanya Gandhi, Charles C Lee
square maze with dimensions of 40 x 40 x 30 (l x w x h in cm; Maze Engineers, Boston, MA)
Science Advances2025
Complementary roles of dorsal and ventral hippocampus in the flexible adaptation of goal-directed behavior.
Maryam Hasantash, Yifei Li, Arturo Torres-Herraez et al.
...group.
Barnes maze
Mice were habituated to a Barnes maze (Ø: 92 cm, 20 holes, 95 cm high; MazeEngineers) with spatial cues around the testing room for 10 to 15 min. The day after the habituation...
Food reward entrainment increases mealtime anxiety in goldfish via a ghrelin-dependent mechanism
Lisbeth Herrera-Castillo, Nuria Saiz, Nuria de Pedro et al.
...and white background preference test
A rectangular tank with opaque walls and bottom (Maze Engineers) was employed to conduct a test of scototaxis following previously described protocols. The tank...
A novel CD71 Centyrin:Gys1 siRNA conjugate reduces glycogen synthesis and glycogen levels in a mouse model of Pompe disease.
Bryce D Holt, Samuel J Elliott, Rebecca Meyer et al.
...both forearms over three trails was calculated.
Rotarod
Mice were tested on a six-lane rotarod (Maze Engineers) set to accelerate from 4 to 40 rpm over 180 s. Latency was determined by mice meeting the...
Accurate Tracking of Locomotory Kinematics in Mice Moving Freely in Three-Dimensional Environments
Bogna M Ignatowska-Jankowska, Lakshmipriya I Swaminathan, Tara H Turkki et al.
...rim to track movement. TRM running tasks were conducted on a motorized single-lane treadmill (MazeEngineers), with markers attached to the belt at 20 cm intervals to monitor speed (Movie 5). All...
Presymptomatic targeted circuit manipulation for ameliorating Huntington's disease pathogenesis
Ebenezer C Ikefuama, Ashley N Slaviero, Alexander D Silvagnoli et al.
PA apparatus (Maze Engineers, Skokie, IL)
GeroScience2025
Growth hormone-deficient Ames dwarf mice resist sarcopenia and exhibit enhanced endurance running performance at 24 months
Matthew J Johnston, Sharlene G Rakoczy, LaDora V Thompson et al.
...all four limbs to reduce variability and improve consistency. Grip strength was recorded via Maze Engineers Grip Strength Instrument (Skokie, IL, USA). The apparatus has a maximum tensile force range from...
Conditional Dmd ablation in muscle and brain causes profound effects on muscle function and neurobehavior.
Muthukumar Karuppasamy, Katherine G English, James R Conner et al.
...spent in close interaction with familiar or unfamiliar mouse were measured. T-maze and Y-maze (Maze Engineers; Skokie, IL) cohort assessments were performed using previously described with video recordings...
Magel2 in hypothalamic POMC neurons influences the impact of stress on anxiety-like behavior and spatial learning associated with a food reward in male mice.
Sangbhin Lee, Young-Hwan Jo
...were placed in the center of a chamber measured 40 cm (length) × 40 cm (width) × 40 cm (height) (Maze Engineers) and allowed to explore the chamber for 5 min freely (750 lux throughout the chamber). The center...
Targeting microRNA-dependent control of X chromosome inactivation improves the Rett Syndrome phenotype
Song Lou, Rachisan DJiake Tihagam, Urszula N. Wasko et al.
mice were tested on a commercial rotarod apparatus (MAZE ENGINEERS)
Bio-protocol2025
A Protocol to Assess Time-of-Day-Dependent Learning and Memory in Mice Using the Novel Object Recognition Test
Jordan Mar, Matthew A McGregor, Vishnuvasan Raghuraman et al.
...required, as many commercial arenas are available, for example, from Maze Engineers (https://maze.conductscience.com).
b. It is recommended that all interior surfaces of the arena have a matte finish to reduce...
Pathogenic variants in SMARCA1 cause an X-linked neurodevelopmental disorder modulated by NURF complex composition.
Ghayda M Mirzaa, Keqin Yan, Raissa Relator et al.
...for 30 minutes before testing. The Morris water maze is a large plastic tank (~132 cm diameter, Maze Engineers, Skokie, IL) filled with tap water maintained at 22 °C and made opaque with white tempera paint....
A novel gene edited rat model of cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy (CARASIL).
Brittany Monte, Judianne Davis, Xiaoyue Zhu et al.
...field
A total of n = 11 CRHTRA1 and n = 13 WT rats aged to 12 M were used. The open field (Maze Engineers, Skokie, IL) measures 60 cm x 60 cm and is constructed with matte black acrylic floor and walls....
Autophagic impairment in sleep-wake circuitry is linked to sleep loss at the early stages of Alzheimer's disease
Christopher Daniel Morrone, Arielle A Tsang, W Haung Yu
...a circular field was utilized with 20 holes (1 escape box) along the outside (92 cm diameter, Maze Engineers), and an overhead camera acquired trials in EthoVision XT (Noldus) software. After a habituation...
Reduced IGF-1 signaling fails to limit Alzheimer's disease progression in a novel rat model of IGF-1R haploinsufficiency.
Sushma Narayan, Kai Mao, Alberto R Williams-Medina et al.
...in the corner of an evenly lit square arena (80 cm × 80 cm, 41 cm height) without visual cues (Maze Engineers; Skokie, IL), and average velocity, track length, activity level, and time spent in the central...
Genetically diverse mice exhibit divergent domain-specific, sex-dependent behavioral outcomes following exposure to early life stress
Jennifer Nguyen, Kevin Shimizu, Varvara Zlotnik et al.
...(0°; 35 × 11.2 cm) that is positioned out of sight of a mouse located on the central platform (MazeEngineers, Skokie, IL). This configuration provides unfamiliar open spaces with no “safe” zones (e.g.,...
Cognitive Function, Sleep, and Neuroinflammatory Markers in Mice Exposed to Very Long-Term Intermittent Hypoxia
Clementine Puech, Mohammad Badran, Max B Barrow et al.
...set-ups were cleaned with 70% ethanol to prevent odor cues. All the mazes were purchased from Maze Engineers (Cambridge, MA, USA). The tests were recorded from a vertical point of view with a video camera...
AAV delivery of full-length SYNGAP1 rescues epileptic and behavioral phenotypes in a mouse model of SYNGAP1-related disorders.
Meagan A Quinlan, Rong Guo, Andrew G Clark et al.
...field test
General locomotor behavior of mice was evaluated in multi-unit open field mazes (Maze Engineers). The center zone consists of a 20 × 20 cm area in the middle of the arena for center vs....
Evaluation of the Therapeutic Potential of Synthetic Growth Hormone-Releasing Hormone Antagonist MIA-690 as a Cognitive Modulator in a Mouse Model of Gulf War Illness
Luis Manuel Salgueiro-Tosta, Arumugam Radhakrishnan Jayakumar, William Kochen et al.
...GWI exposure model. The MWM consisted of a pool 160 cm diameter and 60 cm in height (Maze Engineers, Skokie, IL, USA) filled with water opaqued with non-toxic white tempera (Blick Art Materials,...
Vasoactive neuropeptide dysregulation: A novel mechanism of microvascular dysfunction in vascular cognitive impairment.
Willians Tambo, Keren Powell, Steven Wadolowski et al.
...two‐phase Y‐maze protocol. The testing apparatus consisted of a symmetrical Y‐shaped maze (MazeEngineers, USA) with three identical arms (40 cm length × 8 cm width × 15 cm height) positioned at...
Opposing roles of microglial and macrophagic C3ar1 signaling in stress-induced synaptic and behavioral changes
Ashutosh Tripathi, Alona Bartosh, Dania Jose et al.
...interactions initiated by test mouse were considered in this test.
Y-maze test
We used Y-maze (Maze Engineers) to perform a continuous spontaneous alternation test measuring spatial working memory deficits....
Photobiomodulation Strengthens Muscles via Its Dual Functions in Gut Microbiota.
Prabhat Upadhyay, Asmita Banstola, Brijesh Bhayana et al.
...period was implemented for all mice, with the initial settings of the shock grid at 0.9 mA (Maze Engineers Automated Treadmill, Skokie, IL, USA), after which a progressive exercise training regimen was...
Hyperhomocysteinemia-induced VCID results in visual deficits, reduced neuroinflammation and vascular alterations in the retina
Erica M Weekman, Colin B Rogers, Tiffany L Sudduth et al.
...Guide for the Care and Use of Animals in Research.
ViS4M
The Visual-Stimuli 4-arm Maze (ViS4M) (MazeEngineers, Skokie, IL), initially described by Vit et al., was performed according to the original paper...
The Journal of neuroscience : the official journal of the Society for Neuroscience2025
mWAKE in the Central Amygdala Regulates Fear Learning and Memory
Jiali Xiong, Anuradha Mehta, Qiang Liu et al.
Fear Conditioning Chambers (Maze Engineers Inc.)
Theranostics2025
An AIM2 inflammasome biomimetic mineralization inhibitor for vascular dementia therapy
Yueqi Zhang, Lixian Jiang, Rongrong Wu et al.
Barnes maze (Maze Engineers, Boston, MA, USA)
Scientific Reports2025
Dietary fiber modulates gut microbiota and lipid metabolism ameliorating Alzheimer's pathology in 5xFAD mice.
Yuhai Zhao, Christopher M Taylor, Walter J Lukiw et al.
...on modifications to the habituation phase. The apparatus used was an open-field box (50 × 50 cm, Maze Engineers, Catalog #3201). Mice at 6 months of age underwent a habituation session in an empty arena,...
Profiling of research domain criteria-based behaviors following single prolonged stress in male C57BL/6J mice.
Krysten P O'Hara, Savanna M King, Rachel D Penrod et al.
>). Briefly, mice were placed onto the EPM (matte gray acrylic; wall height: 20 cm, arm length: 35 cm, arm width: 5 cm; Conduct Science; Skokie, IL) into the central zone between the closed and open arms with its head facing away from the experimenter tow
Asymmetric Dimethylarginine Disrupts Tumor Antigen Presentation in Breast Cancer.
Mei Li, Yi-Ling Chen, Lilly M Pearce et al.
ntigens was quantified using Cellcyte X (CYTENA, Boston, MA, USA) for imaging analysis and flow cytometry (BSN-ZS-AS7S, Conduct Science, Skokie, IL, USA) for quantitative assessment. The CellCyte X system has a resolution of 0.345 µm/pixel at 10× objectiv
Electric field stimulation directs target-specific axon regeneration and partial restoration of vision after optic nerve crush injury.
Timothy Kim, Ege Iseri, Micalla G Peng et al.
as previously described [41]. A clear, open-top plexiglass box (Conduct Science, Skokie, IL) measuring 82 x 82 cm was placed on a 3-foot-tall table with half of the box protruding. A black-and-white
A bespoke water T-maze apparatus and protocol: an optimized, reliable, and repeatable method for screening learning, memory, and executive functioning in laboratory mice
Jeremy Davidson Bailoo, Susan E Bergeson, Igor Ponomarev et al.
...area of 100 cm2 (10 × 10 cm) and a height of 10 cm. Both the MWM and T-Insert were built by Maze Engineers and housed at the Garrison Institute of Aging (GIA) behavioral facility at TTUHSC.
Animals were...
Increased regional activity of a pro-autophagy pathway in schizophrenia as a contributor to sex differences in the disease pathology
Kathryn J Bjornson, Amanda M Vanderplow, Aishwarya I Bhasker et al.
...was done using methods from our previous work. A gray open field box purchased from Maze Engineers was used for habituation and for both trials. The box was 40 cm wide, 40 cm long, and 30 cm tall....
Serotonin as a biomarker of toxin-induced Parkinsonism
Anna Marie Buchanan, Sergio Mena, Iman Choukari et al.
elevated zero maze, tail suspension test apparatus, and open field activity chamber (Maze Engineers, Boston, MA, USA)
Nature Cardiovascular Research2024
Cardiac NAD<sup>+</sup> depletion in mice promotes hypertrophic cardiomyopathy and arrhythmias prior to impaired bioenergetics.
Khanh V Doan, Timothy S Luongo, Thato T Ts'olo et al.
To evaluate exercise capacity and endurance, mice were run on a treadmill system (Maze Engineers: Treadmill 2009, Model No. MZ-3.0-8-52) with a stepwise acceleration protocol.
Comparative effect of atorvastatin and risperidone on modulation of TLR4/NF-κB/NOX-2 in a rat model of valproic acid-induced autism
Eman A E Farrag, Mona H Askar, Zienab Abdallah et al.
...in dim regions for a prolonged duration. The dark-bright box was executed in a box with 2 parts (MazeEngineers, USA). The test box (51 length × 51 width × 40 cm height) contained one more significant bright...
Intermittent cytomegalovirus infection alters neurobiological metabolism and induces cognitive deficits in mice
Harrison, M. A., Morris, S. L., Rudman, G. A. et al.
The Y-maze (Maze Engineers, Skokie, IL) consisted of three equal arms...
Abstract
Biology of sex differences2024
Early adversity causes sex-specific deficits in perforant pathway connectivity and contextual memory in adolescent mice
Rafiad Islam, Jordon D White, Tanzil M Arefin et al.
...test was done as previously described. Briefly, mice were allowed to explore a 40 × 40 cm arena (Maze Engineers, # 3201) illuminated at 60 l × for 5 min during which the distance traveled and the time spent...
Prophylactic senolytic treatment in aged mice reduces seizure severity and improves survival from Status Epilepticus
Tahiyana Khan, Abbas I Hussain, Timothy P Casilli et al.
...maze consists of an elevated circular platform (92 cm) with 20 holes (5 cm) around the perimeter (Maze Engineers). The target hole consisted of an escape box, and the remaining holes had a false floor. The...
The Journal of neuroscience : the official journal of the Society for Neuroscience2024
Neuronal Ensembles in the Amygdala Allow Social Information to Motivate Later Decisions
Henry W Kietzman, Gracy Trinoskey-Rice, Esther H Seo et al.
three-chamber social interaction apparatus (MazeEngineers, 40.5 x 60 x 25 cm)
Military Medical Research2024
FDA-approved cannabidiol [Epidiolex®] alleviates Gulf War Illness-linked cognitive and mood dysfunction, hyperalgesia, neuroinflammatory signaling, and declined neurogenesis
Maheedhar Kodali, Leelavathi N Madhu, Venkata Sai Vashishta Kolla et al.
...sucrose preference test (SPT). Hyperalgesia was ascertained using an electric Von Frey apparatus (Maze Engineers), which measured the force [millinewtons (mN)] exerted by the monofilament applied...
Methylphenidate differentially affects the social ultrasonic vocalizations of wild-type and prodromal Parkinsonian rats
Sarah A Lechner, Cynthia A Kelm-Nelson, Michelle R Ciucci
open-field arena (a square, empty arena, 60 cm x 60 cm surrounded by walls 40 cm in height, Maze Engineers, Illinois)
International journal of molecular sciences2024
In Vivo Evaluation of Nose-to-Brain Delivery of Liposomal Donepezil, Memantine, and BACE-1 siRNA for Alzheimer's Disease Therapy
David Lee, Andrew M Shen, Milin Shah et al.
...20 cm in height. These arms were attached at 120-degree angles, creating a maze-like structure (Maze Engineers, Skokie, IL, USA). The mouse was placed at one end and given 5 min to explore the three arms...
A subset of dopamine receptor-expressing neurons in the nucleus accumbens controls feeding and energy homeostasis
Yiqiong Liu, Ying Wang, Zheng-Dong Zhao et al.
...Each session lasted 60 min. Data were collected using the MazeEngineers behavioral software (Conduct Science).
Optogenetic modulations of post-fasted food intake
Mice received 20 min of laser stimulation...
Compensatory changes after spinal cord injury in a remyelination deficient mouse model
S B Manesh, B R Kondiles, S Wheeler et al.
variable speed rodent treadmill (Maze Engineers)
Frontiers in behavioral neuroscience2024
Behavioral, neurotransmitter and transcriptomic analyses in male and female Fmr1 KO mice
Deirdre M McCarthy, Cynthia Vied, Mia X Trupiano et al.
Plexiglass tube approximately 17 inches long and 1 inch internal diameter (Maze Engineers, Skokie, IL)
Cell Reports2024
Autism-associated CHD8 controls reactive gliosis and neuroinflammation via remodeling chromatin in astrocytes.
Platon Megagiannis, Yuan Mei, Rachel E Yan et al.
...Briefly, mice were placed in the center of an empty testing area (40 × 40 cm; 30cm height, Maze Engineers) and allowed to move freely for 10 min. The session was recorded and quantified using the HVS...
Cognitive behavioral phenotyping of DSCAM heterozygosity as a model for autism spectrum disorder
Ryan C Neff, Katherine A Stangis, Ujjawal Beniwal et al.
The apparatus (Maze Engineers, Skokie, IL) consisted of two chambers (20 x 20 x 20 cm)
Parasitology2024
Gastrointestinal nematode infection during pregnancy and lactation enhances spatial reference memory and reduces indicators of anxiety-like behaviour in uninfected adult female mouse offspring
Sophia Noel, Ryan LaFrancois, Marilyn E Scott
...born to uninfected dams (Patil et al.,). As previously described (Noel et al.,), the Barnes Maze (Maze engineers, 412 Wilmette Ave, Glenview, IL 60025, USA) is an opaque circular platform (diameter: 92 cm,...
Prior Negative Experience Biases Activity of Medial Amygdala during Interstrain Social Engagement in Male Rats.
Alexandra C Ritger, Nimah M Rasheed, Mallika Padival et al.
...preference test was performed in a three-chamber apparatus with an open top (100 × 45 × 40 cm, Maze Engineers). The chamber was divided into three compartments (center 25 × 45 × 40 cm) with a 13 cm opening...
Gamma frequency connectivity in frontostriatal networks associated with social preference is reduced with traumatic brain injury
Morteza Salimi, Tianzhi Tang, Milad Nazari et al.
...5 days).
Behavioral Apparatus
We used a standard three-chamber maze, 80 × 40 × 40 cm in size (Maze Engineers, Skokie, IL, USA). The three-chamber maze had a clear polycarbonate bottom, black sides and...
M2 receptors are required for spatiotemporal sequence learning in mouse primary visual cortex
Susrita Sarkar, Catalina Martinez Reyes, Cambria M Jensen et al.
40 x 40 x 30-cm box (Maze Engineers)
Nature Communications2024
Accumulation of F-actin drives brain aging and limits healthspan in Drosophila
Edward T Schmid, Joseph M Schinaman, Naomi Liu-Abramowicz et al.
...training
Aversion training was performed as described in using a system from MazeEngineers (Conduct Science). Briefly, flies were exposed to a neutral odor (3-octanol) by air pump in a training chamber for...
Cerebral Proteomic Changes in the rTg-D Rat Model of Cerebral Amyloid Angiopathy Type-2 With Cortical Microhemorrhages and Cognitive Impairments
Joseph M Schrader, Mark Majchrzak, Feng Xu et al.
...arm maze is a clear acrylic 8 arm maze with arms radiating from an octagonal center platform (Maze Engineers, Skokie, IL). Training on the maze was preceded by 3 habituation days during which the rats were...
PINK1 knockout rats show premotor cognitive deficits measured through a complex maze
Isabel Soto, Vicki A Nejtek, David P Siderovski et al.
...North Texas Health Science Center (UNTHSC) and the ACURO at the Department of Defense.
The CWM (MazeEngineers; Skokie, IL) is made of acrylic and consists of multiple arms arranged to produce a maze with...
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research2024
ATP1A1-linked diseases require a malfunctioning protein product from one allele.
Kerri Spontarelli, Victoria C Young, Ryan Sweazey et al.
...speed of 40 RPM. Each trial took a maximum of 3 min. All data included here were obtained with a six lane rotarod from Maze Engineers with a 3 cm diameter rod.
Using a Combination of Novel Research Tools to Understand Social Interaction in the Drosophila melanogaster Model for Fragile X Syndrome
Maja Stojkovic, Milan Petrovic, Maria Capovilla et al.
Drosophila Shallow Chamber (Maze Engineers, Skokie, IL)
eLife2024
Using synchronized brain rhythms to bias memory-guided decisions
John J Stout, Allison E George, Suhyeong Kim et al.
Automated T-maze (MazeEngineers)
Journal of neuroinflammation2024
Nanoligomers targeting NF-κB and NLRP3 reduce neuroinflammation and improve cognitive function with aging and tauopathy
Devin Wahl, Sydney J Risen, Shelby C Osburn et al.
...was performed as previously described. Mice were tested using the DST-110 Digital Force Gauge (Maze Engineers). A total of 5 trials were performed per mouse and the highest and lowest values were discarded...
Sex-specific effects of alcohol on neurobehavioral performance and endoplasmic reticulum stress: an analysis using neuron-specific MANF deficient mice
Wen Wen, Hui Li, Marisol Lauffer et al.
...36–38, balance beam for batch 2; Day 40, DigiGait for batch 2.
Balance beam
Balance beam test (Conduct Science MazeEngineers, Skokie, IL) was used to assess motor coordination. An 80 cm-long beam is elevated...
ASICs mediate fast excitatory synaptic transmission for tactile discrimination
Akihiro Yamada, Jennifer Ling, Ayaka I Yamada et al.
open field box was made with a black acrylic material, with a dimension of 60 cm x 60 cm x 40 cm (Maze engineers, USA)
Nature2024
Offline ensemble co-reactivation links memories across days
Yosif Zaki, Zachary T Pennington, Denisse Morales-Rodriguez et al.
Barnes maze apparatus (MazeEngineers)
International Journal of Molecular Sciences2024
Prolactin Drives Iron Release from Macrophages and Uptake in Mammary Cancer Cells through CD44.
Reagan Farrell, Nicholas Pascuzzi, Yi-Ling Chen et al.
suspended macrophages were removed and the remaining adherent EO771 cells were analyzed by flow cytometer (BSN-ZS-AS7S, Conduct Science, Skokie, IL, USA) to determine the iron transfer from macrophages. To further validate the cell identity, PE-Cy7-rat ag
Timing matters: Sex differences in inflammatory and behavioral outcomes following repetitive blast mild traumatic brain injury
Baskin, B. M., Logsdon, A. F., Janet Lee, S. et al.
...by 1–2 days.
Elevated zero maze (EZM):
Animals were allowed to explore an elevated zero maze (Maze Engineers, Skokie, IL) for 5 min. Decreased time spent exploring the open arms is thought to reflect an...
University of Washington?ProQuest Dissertations Publishing2023
University of Washington?ProQuest Dissertations Publishing, ?2023.?30246379
Baskin, Britahny M.? ?Central, Peripheral Nervous System Sequelae Following Blast Exposures: A Multi-Organ System Analysis of a Complex Full-Body Injury
Elevated zero maze (EZM): Animals were allowed to explore an elevated zero maze (Maze Engineers, Skokie, IL) for 5 min.
Dissertation
Pathogens (Basel, Switzerland)2023
Influence of RVFV Infection on Olfactory Perception and Behavior in Drosophila melanogaster
Stella Bergmann, Maja C Bohn, Susann Dornbusch et al.
Y-maze (MazeEngineers, Skokie, IL, USA)
IScience2023
Stress-mediated dysregulation of the Rap1 small GTPase impairs hippocampal structure and function
Bjornson, K. J., Vanderplow, A. M., Yang, Y. et al.
...were allowed to explore four novel objects in a square open field box purchased from Maze Engineers (40cm long, 40cm wide, 30cm tall) for 7 minutes (mice not exposed to the novel objects were used...
Identifying applications of virtual reality to benefit the stroke translational pipeline
Matan Bone, Maham Malik, Siobhan Crilly
Virtual Reality Morris Water Maze (MazeEngineers, conductscience.com)
Neuropharmacology2023
Decreased myelin-related gene expression in the nucleus accumbens during spontaneous neonatal opioid withdrawal in the absence of long-term behavioral effects in adult outbred CFW mice
Kristyn N Borrelli, Kelly K Wingfield, Emily J Yao et al.
...in diameter with 20 holes (5 cm diameter) equally spaced around the perimeter (2 cm from edge) (MazeEngineers, Skokie, IL). Four visual cues of different color were placed 30 cm from the edge of the maze and...
virtual Morris Water Maze software (Simian Labs-Maze Engineers, Build 20210821)
Mol Med2023
et al. Serotonin as a biomarker of toxin-induced Parkinsonism
Buchanan, A.M., Mena, S., Choukari, I
...as reported before (Tucker and McCabe). Mice were placed into the closed section of the maze (Maze Engineers, Boston, MA, USA) and were allowed to explore for 5 min. Time spent in the closed section was...
Heme-Induced Macrophage Phenotype Switching and Impaired Endogenous Opioid Homeostasis Correlate with Chronic Widespread Pain in HIV
Chatterjee, T., Arora, I., Underwood, L. B. et al.
...Plate Test
Thermal hyperalgesia was determined in mice using a specifically designed hot plate (MazeEngineers, Skokie, IL, USA). The plate temperature was set to 55 °C. Mouse was placed on the hot plate, and...
High Heme and Low Heme Oxygenase-1 Are Associated with Mast Cell Activation/Degranulation in HIV-Induced Chronic Widespread Pain
Chatterjee, T., Arora, I., Underwood, L. et al.
...the latency to response (in seconds) when mice were placed on a plexiglass-enclosed hot plate (MazeEngineers, Skokie, IL, USA). The hot plate temperature was set to 55 °C, and individual testing began once...
The Journal of neuroscience : the official journal of the Society for Neuroscience2023
Paraventricular Thalamic MC3R Circuits Link Energy Homeostasis with Anxiety-Related Behavior
Dajin Cho, Kyle O'Berry, Ingrid Camila Possa-Paranhos et al.
elevated zero maze (EZM; MazeEngineers)
Environmental and molecular mutagenesis2023
Intergenerational arsenic exposure on the mouse epigenome and metabolic physiology
Mathia L Colwell, Nicole Flack, Amanda Rezabek et al.
Mice were placed in one arm of a standard Y-maze (MazeEngineers, Boston, MA)
bioRxiv2023
Greally, Masako Suzuki, Marija Kundakovic. Early-life stress and ovarian hormones alter transcriptional regulation in the nucleus accumbens resulting in sex-specific responses to cocaine
Devin Rocks, Ivana Jaric, Fabio Bellia et al.
...Our CPP apparatus is custom made (Maze Engineers; Skokie, IL) and consists of two conditioning chambers separated by a corridor with sliding walls...
Biorxiv_fulltext
Molecular Pain2023
Assessment of pain-related behaviors in HIV-1 transgenic rats as a model of HIV-associated chronic pain
E Gryshyna, A., Chatterjee, T., J DeBerry, J. et al.
...was used in analyses.
Heat hyperalgesia
Thermal hyperalgesia was assessed using a hot plate (Maze Engineers). The testing temperature was set to 52.5°C. The heat sensitivity measures were always done...
...Object Recognition (NOR) Procedure:
Mice were habituated to open field arenas (40×40×40cm; MazeEngineers, USA) for 30 minutes on the first day and 15 minutes on the second day. In the single...
Estradiol withdrawal following a hormone simulated pregnancy induces deficits in affective behaviors and increases ?FosB in D1 and D2 neurons in the nucleus accumbens core in mice
Foster, W. B., Beach, K. F., Carson, P. F. et al.
...consists of an open field (40.5 × 40.5 × 30cm) composed entirely of solid, light gray plastic (Maze Engineers, Glenview, IL, USA). Mice were placed in the center of the apparatus and allowed to freely...
An updated Barnes maze protocol for assessing the outcome of controlled cortical impact mouse models of traumatic brain injury
Gee, C. C., Steffen, R., Kievit, F. M.
...Traditional Protocol
Both BM protocols utilized a 93 cm diameter blue platform obtained from Maze Engineers (Skokie, IL, USA) with 20 holes equally spaced around the outside of the platform. Each hole was...
2MDR, a Microcomputer-Controlled Visual Stimulation Device for Psychotherapy-Like Treatments of Mice
Isa Jauch, Jan Kamm, Luca Benn et al.
...behavioral setups. We used our 2MDR system with a regular auditory fear conditioning (FC) system (Maze Engineers) and a TTL trigger unit (Maze Engineers). We isolated the fear conditioning box with acoustic...
"Baf155 regulates skeletal muscle metabolism via HIF-1a signaling"
Kang JS, Kim D, Rhee J et al.
...to the treadmill (DJ2-242 Dual Treadmill, Daejong Instrument, Treadmill for 8 mice LT320, Maze engineers) before running tests. The acclimation scheme was the 10-min running at a speed of 10 m/min for 3...
Young, Ryan Sweazey, Alexandria Padro, Jeannie Lee, Tulio Bueso, Roberto M. Hernandez, Jongyeol Kim, Alexander Katz, Francis Rossignol, Clesson Turner, Caralynn M. Wilczewski, George L. Maxwell, Miguel Holmgren, Jeremy D. Bailoo, Sho T. Yano, Pablo Artigas. ATP1A1-linked diseases require a malfunctioning protein product from one allele
Kerri Spontarelli, Victoria C.
...All data included here were obtained with a six lane rotarod from Maze Engineers with are 3 cm diameter rod...
Biorxiv_fulltext
Scientific Reports2023
Disruptive lysosomal-metabolic signaling and neurodevelopmental deficits that precede Purkinje cell loss in a mouse model of Niemann-Pick Type-C disease
Kim, S., Ochoa, K., Melli, S. E. et al.
...of 100 metal rungs (3 mm each) forming a ladder floor that is raised above the surface (from Maze Engineers). The minimum space between the metal rungs is 1 cm. However, for this study, to challenge the...
Chronic pharmacological activation of SERCA with CDN1163 affects spatial cognitive flexibility but not attention and impulsivity in mice
Benjamin Klocke, Carter Moore, Hayden Ott et al.
...a commercially-obtained circular mouse swimming pool measuring 5 ft in diameter and 31 cm deep (Maze Engineers, MA, USA) was filled with tap water mixed with non-toxic water-based white paint. A video...
...for 15 minutes (pretest) and 5 minutes (test) in a cylinder with 30-cm diameter and 60-cm height (MazeEngineers, Skokie, IL, USA) filled with 30 cm tap water at a temperature of 24°C ± 1°C. Four cylinders were...
Social defeat stress induces genome-wide 5mC and 5hmC alterations in the mouse brain
Kuehner, J. N., Walia, N. R., Seong, R. et al.
...toward an unfamiliar CD1 target animal. The arena was a white open field (40 × 40 cm height; Maze Engineers) maintained in complete darkness supplemented with red lamp lights. 24 h after the final defeat,...
Predictors of prodromal Parkinson's disease in young adult Pink1?/? rats
Lechner, S. A., Welsch, J. M., Pahapill, N. K. et al.
...were assessed using an open field arena [60 cm × 60 cm surrounded by walls 40 cm in height (Maze Engineers, IL)]. Square grid crossings on the floor of the arena were used to track total distance traveled...
Supraphysiologic doses of 17β-estradiol aggravate depression-like behaviors in ovariectomized mice possibly via regulating microglial responses and brain glycerophospholipid metabolism.
Ming Li, Jing Zhang, Wendi Chen et al.
...field test consisted of 5 min trial in a white opaque arena of 45 cm × 45 cm × 30 cm in size (Maze Engineers, Boston, USA). The test arena was divided equally into nine square quadrants. Each mouse was...
A small molecule ligand for the novel pain target, GPR171, produces minimal reward in mice
Max V McDermott, Akila Ram, Matthew T Mattoon et al.
CPP apparatus (Maze Engineers)
Research Square2023
Generation and characterization of a knock-in mouse model for Spastic Tetraplegia, Thin Corpus Callosum, and Progressive Microcephaly (SPATCCM), 24 April 2023, PREPRINT (Version 1) available at
Megan L. Ratz, Greg Leary, Andrea Grindeland et al
...For the Rotarod test, mice from the same cage were placed on the apparatus (Maze Engineers) facing forward at a speed of 4 rpm...
Researchsquare_fulltext
Research square2023
Supraphysiologic doses of 17?-Estradiol aggravate depression-like behaviors in ovariectomized mice possibly via regulating microglial responses and brain glycerophospholipid metabolism, 08 May 2023, PREPRINT (Version 1) available at
Ming Li, Jing Zhang, Wendi Chen et al
...Open field test consisted of 5 min trial in a white opaque arena of 45 cm × 45 cm × 30 cm in size (Maze Engineers, Boston, USA)...
Researchsquare_fulltext
Frontiers in aging neuroscience2023
Concurrent behavioral and electrophysiological longitudinal recordings for in vivo assessment of aging
Christopher Daniel Morrone, Arielle A Tsang, Sarah M Giorshev et al.
Barnes maze (Maze Engineers)
Neuropsychopharmacology2023
The effect of selective nigrostriatal dopamine excess on behaviors linked to the cognitive and negative symptoms of schizophrenia
Moya, N. A., Yun, S., Fleps, S. W. et al.
We then habituated mice to an automated T-maze (Maze Engineers) for 2 days.
Getting ahead of Alzheimer's disease: Early intervention with focused ultrasound
Noel, R. L., Gorman, S. L., Batts, A. J. et al.
...IR-sensitive GigE camera with a transparent cylindrical enclosure measuring 60 cm in diameter (Maze Engineers, Skokie, IL, USA). The table was enclosed within a noise canceling room (MDL 4848 S, Whisper Room...
Acetate supplementation rescues social deficits and alters transcriptional regulation in prefrontal cortex of Shank3 deficient mice
Aya Osman, Nicholas L Mervosh, Ana N Strat et al.
elevated zero maze (Maze Engineers)
Neuron2023
Dorsomedial prefrontal hypoexcitability underlies lost empathy in frontotemporal dementia.
Hannah L Phillips, Huihui Dai, So Yoen Choi et al.
...of all movements and included sleeping and still and alert behaviors as advocated at https://conductscience.com/maze/resources/mouse-ethogram/inactive-behaviors-overview/. (v) Allogrooming, social...
Mammalian genome : official journal of the International Mammalian Genome Society2023
Generation and characterization of a knock-in mouse model for spastic tetraplegia, thin corpus callosum, and progressive microcephaly (SPATCCM)
Megan L Ratz-Mitchem, Greg Leary, Andrea Grindeland et al.
...engaging the grid.
For the Rotarod test, mice from the same cage were placed on the apparatus (Maze Engineers) facing forward at a speed of 4 rpm. Once the mice were in placed, the Rotarod accelerated from 4...
Early-life stress and ovarian hormones alter transcriptional regulation in the nucleus accumbens resulting in sex-specific responses to cocaine
Devin Rocks, Ivana Jaric, Fabio Bellia et al.
...the CPP phenotype to the C57Bl/6J cohort of animals across sex. Our CPP apparatus is custom made (Maze Engineers; Skokie, IL) and consists of two conditioning chambers separated by a corridor with sliding...
Nature and nurture: Comparing mouse behavior in classic versus revised anxiety-like and social behavioral assays in genetically or environmentally defined groups
Janet Ronquillo, Michael T Nguyen, Linnea Y Rothi et al.
...that are positioned out of sight of the animal when it is located on the central platform (MazeEngineers, Skokie, IL). This configuration provides unfamiliar open spaces with no “safe” zones as found in...
Effects of in utero Exposure to CASPR2 Autoantibodies on Neurodevelopment and Autism Spectrum Disorder. School of Medicine at
Su, Julia Y.? ?Donald, Barbara Zucker
Frontiers in Neuroscience2023
Sex linked behavioral and hippocampal transcriptomic changes in mice with cell-type specific Egr1 loss
Swilley, C., Lin, Y., Zheng, Y. et al.
...terminated, and the mouse was removed from the apparatus to prevent thermal injury.
Tail flick
Maze Engineers tail flick device was used to test each individual mouse. Mice were restrained in an A refrainer...
Functional IgG Autoantibodies against Autonomic Nervous System Receptors in Symptomatic Women with Silicone Breast Implants
Talalai, E., Gorobets, D., Halpert, G. et al.
...behavior, and was performed in a standardized arena of 40 × 40 cm made from inert plastic (Maze Engineers, Skokie, IL, USA). For a better habituation, all the animals were placed in the experimental room...
SLC30A10 manganese transporter in the brain protects against deficits in motor function and dopaminergic neurotransmission under physiological conditions.
Cherish A Taylor, Stephanie M Grant, Thomas Jursa et al.
Maze Engineers equipment referenced in supplementary materials.
PI3K block restores age-dependent neurovascular coupling defects associated with cerebral small vessel disease
Thakore P, Yamasaki E, Ali S et al.
...Y-Maze behavioral assay Memory function was assessed using the Y-maze (Maze Engineers, Skokie, IL, USA) using two different configurations...
Biorxiv_fulltext
JCI Insight2023
Liver-expressed antimicrobial peptide 2 elevation contributes to age-associated cognitive decline
Tian J, Guo L, Wang T et al.
...was blinded during the tests. Experiments were performed using the fear-conditioning system from Maze Engineers. On day 1, mice were placed in the fear-conditioning cage for 3 minutes to record pretraining...
Protocol for wireless deep brain stimulation in freely behaving mice with infrared light
Wu, X., Hong, G.
... Locking ball and socket mount Thorlabs TRB2 Power meter Thorlabs S405C Y maze Maze Engineers 3501 Virkon S Amazon ASIN#B0088OKF1E Thermal camera FLIR A325sc Video camera Canon VIXIA HF...
Further Characterization of Multi-Organ DEARE and Protection by 16,16 Dimethyl Prostaglandin E2 in a Mouse Model of the Hematopoietic Acute Radiation Syndrome. Radiat Res. 2023 May 1;199(5):468-489. PMID: 37014943
Wu T, Pelus LM, Plett PA et al.
...memory by spontaneous alternation test in the Y-maze. Mice were placed in one arm of a Y-maze (Maze Engineers, Skokie, IL) and allowed to freely navigate for 10 min. Behavior was tracked via AnyMaze video...
Microglial over-pruning of synapses during development in autism-associated SCN2A-deficient mice and human cerebral organoids. Research Square
Yang, Y., Wu, J., Zhang, J. et al.
...with three arms of 5 cm wide × 35 cm long with 20 cm tall transparent walls placed 120° apart (Maze Engineers). Black shapes (dots, stripes, and squares) were positioned at the end of each arm to serve as...
AJ76 and UH232 as potential agents for diagnosing early-stage Parkinson's disease. Neuropharmacology
Zhou, J., Li, J., Papaneri, A. B. et al.
...of mice.
Rotarod test in normal C57BL/6J mice
Mice were placed on a rotating rod (Mouse 6 Lane, Maze Engineers) with rotation speed gradually increasing from 4 to 40 RPM with an acceleration of 20 rpm2 over a...
AJ76 and UH232 as potential agents for diagnosing early-stage Parkinson's disease
Jingheng Zhou, Jicheng Li, Amy B Papaneri et al.
...of mice.
Rotarod test in normal C57BL/6J mice
Mice were placed on a rotating rod (Mouse 6 Lane, Maze Engineers) with rotation speed gradually increasing from 4 to 40 RPM with an acceleration of 20 rpm2 over a...
Influence of RVFV Infection on Olfactory Perception and Behavior in Drosophila melanogaster.
Stella Bergmann, Maja C Bohn, Susann Dornbusch et al.
athogens-12-00558">2.4. Olfactory Choice Test—Y-MazeTo evaluate the chemosensory responses, a Y-maze (MazeEngineers, Skokie, IL, USA) after Simonnet et al. (2014) [59] was used
Aconitum Alkaloid Songorine Exerts Potent Gamma-Aminobutyric Acid-A Receptor Agonist Action In Vivo and Effectively Decreases Anxiety without Adverse Sedative or Psychomotor Effects in the Rat
Zsolt Kristóf Bali, Nóra Bruszt, Zsombor Kőszegi et al.
...anxiolytic effects of SON were tested in the EOM apparatus.
2.3.2. Apparatus
The EOM apparatus (Maze Engineers, Glenview, IL, USA) consisted of a circular platform placed on 61 cm tall stands. The diameter of...
Logsdon, Suhjung Janet Lee, Brian D. Foresi, Elaine Peskind, William A. Banks, David G. Cook, Abigail G. Schindler. Timing matters: Sex differences in acute and chronic outcomes following repetitive blast mild traumatic brain injury bioRxiv doi:
Britahny M. Baskin, Aric F.
...Elevated zero maze (EZM): Animals were allowed to explore an elevated zero maze (Maze Engineers, Skokie, IL) for 5 min...
Biorxiv_fulltext
Neurobiology of aging2022
Ensemble-specific deficit in neuronal intrinsic excitability in aged mice
Lingxuan Chen, Taylor R Francisco, Austin M Baggetta et al.
Mice were housed in a custom-made homecage (Maze Engineers)
Wiley Online Library - Aging Cell2022
Inhibition of unfolded protein response prevents post?anesthesia neuronal hyperactivity and synapse loss in aged mice
Chen, K., Hu, Q., Gupta, R. et al.
...both objects.
Fear conditioning
Fear conditioning was conducted in a fear conditioning chamber (Maze Engineers). The ANY‐maze software (Stoelting) was used to control the delivery of tones and foot shocks....
et al. A tale of two transmitters: serotonin and histamine as in vivo biomarkers of chronic stress in mice
Hersey, M., Reneaux, M., Berger, S
...as previously described. Each mouse was placed into the closed section of the apparatus (Maze Engineers, Boston, MA, USA) and allowed to explore for 5 min. Time spent in the closed section was measured...
A tale of two transmitters: serotonin and histamine as in vivo biomarkers of chronic stress in mice
Melinda Hersey, Melissa Reneaux, Shane N Berger et al.
Each mouse was placed into the closed section of the apparatus (Maze Engineers, Boston, MA, USA). Tail suspension test apparatus (Maze Engineers, Boston, MA, USA)
Nanotheranostics2022
Dendrimer-2PMPA selectively blocks upregulated microglial GCPII activity and improves cognition in a mouse model of multiple sclerosis
Hollinger KR, Sharma A, Tallon C et al.
...approximately 5 weeks post-immunization. Briefly, mice were placed in the center of the maze (Maze Engineers, Glenview, IL) and trained to find a hidden target platform for 2 trials per day over 4...
Aging exacerbates the brain inflammatory micro-environment contributing to α-synuclein pathology and functional deficits in a mouse model of DLB/PD
Michiyo Iba, Ross A McDevitt, Changyoun Kim et al.
Mice were placed in a 40 cm x 40 cm x 40 cm white plexiglass chamber (Maze Engineers; Boston, MA)
UNIVERSIT� DE MONTR�AL2022
The Role of Astrocytes in the Effects of Early-Life Stress on Lateral Amygdala-Dependent Behaviour. UNIVERSIT' DE MONTR'AL, Thesis for Master of Science (M.Sc.) in Neurosciences
Ifeoluwa, A.
Cellular and molecular bioengineering2022
The Applications and Challenges of the Development of In Vitro Tumor Microenvironment Chips
Annika Johnson, Samuel Reimer, Ryan Childres et al.
ConductScience, Inc., US — Custom microfluidic chips including organ chips, tumor chips, and biosensors
PNAS2022
Transgenerational transmission of aspartame-induced anxiety and changes in glutamate-GABA signaling and gene expression in the amygdala. Proceedings of the National Academy of Sciences, 119(49), e2213120119
Jones, S. K., McCarthy, D. M., Vied, C. et al.
...elevated maze consisting of continuous alternating open and closed areas arranged in a circle (Maze Engineers, Boston, MA). The mouse was placed in an open area of the EZM and allowed to explore the maze...
Proceedings of the National Academy of Sciences of the United States of America2022
Transgenerational transmission of aspartame-induced anxiety and changes in glutamate-GABA signaling and gene expression in the amygdala
Sara K Jones, Deirdre M McCarthy, Cynthia Vied et al.
The EZM is a circular, elevated maze consisting of continuous alternating open and closed areas arranged in a circle (Maze Engineers, Boston, MA)
Nature Communications2022
Social incentivization of instrumental choice in mice requires amygdala-prelimbic cortex-nucleus accumbens connectivity
Henry W Kietzman, Gracy Trinoskey-Rice, Sarah A Blumenthal et al.
...were given 10 min to habituate to the middle section of a large chamber (40 × 20 × 25 cm; MazeEngineers) divided into three sections. Dividers between each section were sliding doors to allow for free...
Compromised Cortical-Hippocampal Network Function From Transient Hypertension: Linking Mid-Life Hypertension to Late Life Dementia Risk
Lai, A. Y., Bazzigaluppi, P., Morrone, C. D. et al.
...was measured by t-test.
Barnes Maze
We conducted all trials except the training of Barnes maze (Maze Engineers) testing in a behavioral suite with spatial cues and an aversive light. Following training to the...
Microvascular Dysfunction in Skeletal Muscle Precedes Myocardial Vascular Changes in Diabetic Cardiomyopathy: Sex-Dependent Differences
Sadi Loai, Xuetao Sun, Mansoor Husain et al.
...3 post-induction (Table 1). In brief, rats were placed on an exercise regime where the treadmill (Maze Engineers, USA) inclination was set at 12° and the speed started at a slow pace of 5 m/min for 2 min. The...
A., Yeger, H., Nunes, S. S., & Cheng, H. "Microvascular Dysfunction in Skeletal Muscle Precedes Myocardial Vascular Changes in Diabetic Cardiomyopathy: Sex-Dependent Differences."
Loai, S., Sun, X., Husain, M. et al.
...3 post-induction (Table 1). In brief, rats were placed on an exercise regime where the treadmill (Maze Engineers, USA) inclination was set at 12° and the speed started at a slow pace of 5 m/min for 2 min. The...
Distinct Cecal and Fecal Microbiome Responses to Stress Are Accompanied by Sex- and Diet-Dependent Changes in Behavior and Gut Serotonin
Lyte, J. M., Koester, L. R., Daniels, K. M. et al.
...Maze
The Barnes maze was conducted as previously described. In brief, the maze (Maze Engineers; Skokie, IL) consisted of 20 equally spaced holes each 5 cm in diameter with a single black...
C1q deletion exacerbates stress-induced learned helplessness behavior and induces neuroinflammation in mice. Transl Psychiatry
Madeshiya, A.K., Whitehead, C., Tripathi et al.
...(initiated by the test mouse only) was video recorded for 5 m.
Y-maze test
A Y-maze apparatus (Maze Engineers) was used to score the continuous and spontaneous alternation in mice. The Y-maze consists of...
C1q deletion exacerbates stress-induced learned helplessness behavior and induces neuroinflammation in mice
Amit Kumar Madeshiya, Carl Whitehead, Ashutosh Tripathi et al.
...(initiated by the test mouse only) was video recorded for 5 m.
Y-maze test
A Y-maze apparatus (Maze Engineers) was used to score the continuous and spontaneous alternation in mice. The Y-maze consists of...
Kamshilin, A. A. "Physical Training Reverses the Impaired Cardiac Autonomic Control and Exercise Tolerance Induced by Right-Side Vagal Denervation," in IEEE Access, vol. 10, pp. 10393-10401
Mamontov, O.V., Karpov, A.A, Minasian, S. M. et al.
Biorxiv2022
Morris, Grace A. Rudman, Daniel J. Rittenhouse, Chandler H. Monk, Siva SVP Sakamuri, MaryJane J. Jones, Md Mehedi Hasan, Mst Shamima Khatun, Hanyun Wang, Lucas P. Garfinkel, Elizabeth B. Norton, Chad Steele, Sangku Kim, Jay K. Kolls, S. Michal Jazwinski, Ricardo Mostany, Prasad VG Katakam, Elizabeth B. Engler-Chiurazzi, Kevin J. Zwezdaryk
Mark A.A. Harrison, Sara L.
...The floor of both chambers contains metal rungs on the floor connected to a shock delivery apparatus (Maze Engineers)...
Biorxiv_fulltext
Med. Forum2022
Borges , S. I. Farooqui , R. A. Siddiqui, S. N. Shah and Am. A. Khan "Aerobic Exercise: A Potent Method to Improve Morphology of Bone " in
M. Mukadam, K. J. J.
Translational Neurodegeneration2022
Parvalbumin neuroplasticity compensates for somatostatin impairment, maintaining cognitive function in Alzheimer's disease. Transl Neurodegener 11, 26 (2022)
Morrone, C.D., Lai, A.Y., Bishay et al.
...in the figure legends.
Barnes maze
All rats were naïve to behavioral assessment. Barnes maze (Maze Engineers, Boston, MA) testing was conducted in a behavioral suite with spatial cues, with an aversive...
Parvalbumin neuroplasticity compensates for somatostatin impairment, maintaining cognitive function in Alzheimer's disease
Christopher Daniel Morrone, Aaron Yenhsin Lai, Jossana Bishay et al.
...in the figure legends.
Barnes maze
All rats were naïve to behavioral assessment. Barnes maze (Maze Engineers, Boston, MA) testing was conducted in a behavioral suite with spatial cues, with an aversive...
Sophia C Noel, Liana Fortin-Hamel, Manjurul Haque et al.
The OFT/OLT arena (Maze engineers, 412 Wilmette Ave, Glenview, IL 60025, USA)
Antioxidants2022
Effect of Dietary Grapes on Female C57BL6/J Mice Consuming a High-Fat Diet: Behavioral and Genetic Changes
Parande, F., Dave, A., Park, E. et al.
...was conducted with an eight-armed commercially available radial arm maze with a center platform (MazeEngineers, Skokie, IL, USA). The mice were habituated to the radial arm maze for two days for 10 min per...
Pathological tau and reactive astrogliosis are associated with distinct functional deficits in a mouse model of tauopathy.
Patel H., Martinez P., Perkins A. et al.
Mice were subjected to the Y-Maze (MazeEngineers) test described in...
PMC Full Text
Neurobiology of Aging2022
Pathological tau and reactive astrogliosis are associated with distinct functional deficits in a mouse model of tauopathy
Patel Henika, Mart'nez Pablo
...and physiological assays
Spontaneous alternation Y-maze:
Mice were subjected to the Y-Maze (MazeEngineers) test described in, with modifications. Mice were allowed to freely explore the maze for 10 min....
Explicit memory, anxiety and depressive like behavior in mice exposed to chronic intermittent hypoxia, sleep fragmentation, or both during the daylight period
Clementine Puech, Mohammad Badran, Alexandra R Runion et al.
...set-ups were cleaned with ethanol 70% to prevent odor cues. All mazes were purchased at Maze Engineers (Cambridge, MA, USA). EPMT and NOR were recorded from a vertical point of view with a video...
Assessment of Binge-Like Eating of Unsweetened vs. Sweetened Chow Pellets in BALB/c Substrains
Katherine D Sena, Jacob A Beierle, Kayla T Richardson et al.
...observed in ByJ mice could be explained by a lack of preference between chow and palatable food (Maze Engineers.,). In order to determine if there is a difference in novelty preference, a novelty preference...
A Pitx3-deficient developmental mouse model for fine motor, olfactory, and gastrointestinal symptoms of Parkinson's disease
Bin Song, Jacob W Feldmann, Shibo Cao et al.
The Y-maze was purchased from Maze Engineers (Cambridge, MA, USA)
Science advances2022
Alzheimer's disease: Ablating single master site abolishes tau hyperphosphorylation
Kristie Stefanoska, Mehul Gajwani, Amanda R P Tan et al.
A hidden platform (12.6 cm in diameter, 1 cm below water surface, ConductScience)
Journal of Neuroscience2022
C., Chang, M., Zhao, S.,Grudzien, M., Oginsky, Y., Yang, S, E., Kwo
Mice were placed in an acrylic chamber equipped with a stainless-steel grid floor through which electric shock could be delivered (MazeEngineers).
PMC Full Text
bioRxiv2022
nhibitory interneurons within the deep dorsal horn integrate convergent sensory input to regulate motor performance Nofar Ozeri-Engelhard, Mark A Gradwell, Olivier D Laflamme, Aman Upadhyay, Adin Aoki, Tara Shrier, Melissa Gandhi, Melissa Gonzalez, Jaclyn T Eisdorfer, Gloria Abbas- Zadeh, Nusrath Yusuf, Jordan Katz, Michael Haas, Turgay Akay, Victoria Abraira bioRxiv doi:
...Horizontal ladder test Mice were trained for 2 days to cross a 60 cm long, horizontal ladder (Maze Engineers, Skokie, USA)...
Biorxiv_fulltext
Plos Biology2022
Vanderplow, A., Kermath, B., Bernhardt, C., Gums, K., Seablom, E., Radcliff, A., Ewald, A., Jones, M., Baker, T., Watters, J. and Cahill, M
PLoS Biol2022
A feature of maternal sleep apnea during gestation causes autism-relevant neuronal and behavioral phenotypes in offspring
Vanderplow AM, Kermath BA, Bernhardt CR et al.
...as animals must maintain and update a mental log of arm entries. The Y-maze was purchased from Maze Engineers (Skokie, IL, USA), with each arm 11-cm wide and 50-cm long. Y-maze methods were adopted from our...
Beach, Paige F. Carson, Kagan C. Harris, Brandon L. Alonso, Leo T. Costa, Roy C. Simamora, Jaclyn E. Corbin, Keegan F. Hoag, Sophia I. Mercado, Anya G. Bernhard, Cary H. Leung, Eric J. Nestler, Laura E. Been bioRxiv doi:
William B. Foster, Katherine F.
...The apparatus consists of an open field (40.5 × 40.5 × 30cm) composed entirely of solid, light gray plastic (Maze Engineers, Glenview, IL, USA)...
Biorxiv_fulltext
Sci Rep 11, 9031 (2021)2021
et al. Altered neural oscillations and behavior in a genetic mouse model of NMDA receptor hypofunction
Aguilar, D.D., Radzik, L.K., Schiffino, F.L
...at 2 kHz, and low pass filtered at 200 Hz.
Social task-elicited gamma
We utilized a 3 chamber (Maze Engineers, Boston, MA, USA) task protocol modified from DeVito, et al. portrayed in Fig. 1A. SRKO mice and...
Altered neural oscillations and behavior in a genetic mouse model of NMDA receptor hypofunction
David D Aguilar, Leana K Radzik, Felipe L Schiffino et al.
We utilized a 3 chamber (Maze Engineers, Boston, MA, USA) task protocol
Frontiers in Cell and Developmental Biology2021
Developmental Disruption of Erbb4 in Pet1+ Neurons Impairs Serotonergic Sub-System Connectivity and Memory Formation
Barettino, C., Ayl'n, A., Ort', L. et al.
...
2.4.8 Contextual Fear Conditioning
Fear memory was tested using the Fear Conditioning system (Maze Engineers, Boston, USA) in an acrylic plastic cage of 17 × 17 × 25 cm placed over a shock generator grid....
The Effects of Lavender and Peppermint Essential Oils on Anxiety-Like Behaviors in Rodents. 2021, Undergraduate Honors Program, Malone University, Honors Thesis
Beakas, J.A.
These arms are 50 cm long x 10 cm wide (Maze Engineers, n.d.). Opposing arms match each other, meaning that the open arms are opposite each other and the enclosed arms are opposite each other (Maze Engineers, n.d.).
Dissertation
The Journal of neuroscience : the official journal of the Society for Neuroscience2021
A Cortico-Cortical Pathway Targets Inhibitory Interneurons and Modulates Paw Movement during Locomotion in Mice
Chia-Wei Chang, Meiling Zhao, Samantha Grudzien et al.
an acrylic chamber equipped with a stainless-steel grid floor through which electric shock could be delivered (MazeEngineers)
Wiley Online Library2021
Generation and basic characterization of a gene-trap knockout mouse model of Scn2a with a substantial reduction of voltage-gated sodium channel Nav 1.2 expression. Genes Brain Behav 20(4):e12725
Eaton, M., Zhang, J., Ma, Z. et al.
BioMedCentral2021
Neuropathological and behavioral characterization of aged Grn R493X progranulin-deficient frontotemporal dementia knockin mice. Acta Neuropathol Commun
Frew, J., Nygaard, H.B.
...The test consisted of one 10 min trial in a white opaque 40 cm × 40 cm × 30 cm arena (Maze Engineers)...
Neuropathological and behavioral characterization of aged Grn R493X progranulin-deficient frontotemporal dementia knockin mice
Jonathan Frew, Haakon Berge Nygaard
...(Grn+/+). The test consisted of one 10 min trial in a white opaque 40 cm × 40 cm × 30 cm arena (Maze Engineers). The center zone was defined as a square covering 16% of the total area (16 cm × 16 cm central...
The Rap1 small GTPase is a critical mediator of the effects of stress on prefrontal cortical dysfunction.
B A Kermath, A M Vanderplow, K J Bjornson et al.
Testing was performed in a gray open field box 40cm long, 40cm wide, and with a height of 30cm purchased from Maze Engineers. 4 different objects approximately 8 cm tall were placed in the arena.
Skeletal Muscle Microvascular Dysfunction Manifests Early in Diabetic Cardiomyopathy
Sadi Loai, Yu-Qing Zhou, Kyle D W Vollett et al.
treadmill (Maze Engineers, USA)
Frontiers2021
Skeletal Muscle Microvascular Dysfunction Manifests Early in Diabetic Cardiomyopathy. Front. Cardiovasc. Med
Loai S, Zhou Y-Q, Vollett KDW et al.
...at 3 months post-diabetes. All rats were placed on an exercise regime where the treadmill (Maze Engineers, USA) inclination was set at 12° and the speed started at a slow pace of 5 m/min for 2 min. The...
Effect of exercise on peritoneal microenvironment and progression of ovarian cancer
Madeline J Morrisson, Fangfang Bi, Kevin Yang et al.
An automated 5-lane mouse treadmill (Maze Engineers, Skokie, IL) was used in the forced running model
American Journal of Cancer Research2021
J., Bi, F., Yang, K., Cady, S. L., Hartwich, T. M., Cerchia, A. P., Li, Z., Kim, J., Irwin, M. L., & Yang-Hartwich, Y. "Effect of exercise on peritoneal microenvironment and progression of ovarian cancer " in the
Morrisson, M
An automated 5-lane mouse treadmill (Maze Engineers, Skokie, IL) was used in the forced running model.
PMC Full Text
International Journal of Neuroscience2021
Hippocampal neuroinflammation following combined exposure to cyclophosphamide and naproxen in ovariectomized mice
Pavlock, S., McCarthy, M. D., Kesarwani, A. et al.
Animals : an open access journal from MDPI2021
Can the Hole-Board Test Predict a Rat's Exploratory Behavior in a Free-Exploration Test?
Wojciech Pisula, Klaudia Modlinska, Katarzyna Goncikowska et al.
...used a square hole–board arena measuring 600 × 600 × 450 mm (Hole–board for rats, manufactured by MazeEngineers, Skokie, IL, USA) (Figure 1). The transparent Plexiglas walls were covered to prevent the animals...
Spinophilin limits GluN2B-containing NMDAR activity and sequelae associated with excessive hippocampal NMDAR function
Salek, A. B., Bansal, R., Berbari, N. F. et al.
...120 cm MWM pool (Maze engineers, Cambridge, MA), Heater (Maze engineers), Platform (30cm, Maze engineers), Gantry (Maze engineers)...
Biorxiv_fulltext
Cell Reports2021
CCR2 deficiency alters activation of microglia subsets in traumatic brain injury
Somebang, K., Rudolph, J., Imhof, I. et al.
...at 4 weeks post-TBI at the San Francisco VA Animal Behavior Core Facility. A swimming pool (Maze Engineers) filled with opaque water was monitored using video tracking software, Ethovision XT13 (Noldus),...
Downregulating carnitine palmitoyl transferase 1 affects disease progression in the SOD1 G93A mouse model of ALS
Michael Sloth Trabjerg, Dennis Christian Andersen, Pam Huntjens et al.
...were counted by four blinded raters.
Y-maze test
The y-maze test was constructed according to Maze Engineers (USA). The mice were placed in the y-maze for 5 min to freely explore the three arms. The y-maze...
Pillai, A., Amit Madeshiya, Li, Y., Khodadadi, H., Ahmed, A., O., Turecki, G., Baban, B., Pillai, A. Type 1 interferon mediates chronic stress-induced neuroinflammation and behavioral deficits via complement component 3-dependent pathway. Mol Psychiatry
Tripathi, A., Whitehead, C., Surrao, K.
Y-maze (Maze Engineers) was used to perform a continuous spontaneous alternation test.
Type 1 interferon mediates chronic stress-induced neuroinflammation and behavioral deficits via complement component 3-dependent pathway
Ashutosh Tripathi, Carl Whitehead, Katelyn Surrao et al.
...was of similar age, same-sex, and similar weight as the test mouse.
Y-maze test
Y-maze (Maze Engineers) was used to perform a continuous spontaneous alternation test. There were three arms in Y-maze...
Trabjerg, M.S., Andersen, D.C., Huntjens, P., Egelund Oklinski, K., Bolther, L., Hald, J., L., Baisgaard A., E., M'rk, K., Warming, N., Kullab, U., B., Kroese L., J.,, Pritchard, C., E., J., Huijbers, I., J., Vestergaard Nieland J, D,.Downregulating carnitine palmitoyl transferase 1 affects disease progression in the SOD1 G93A mouse model of ALS. Commun Biol
Neuron2021
Akt-mTOR hypoactivity in bipolar disorder gives rise to cognitive impairments associated with altered neuronal structure and function
Amanda M Vanderplow, Andrew L Eagle, Bailey A Kermath et al.
...plastic open field box with dimensions of 40cm wide, 40cm long, and a 30cm height was purchased (Maze Engineers), and the box surrounded by distal spatial cues. The floor of the box contained a square textured...
Conjunctive spatial and self-motion codes are topographically organized in the GABAergic cells of the lateral septum
Suzanne van der Veldt, Guillaume Etter, Coralie-Anne Mosser et al.
...place paradigm: Mice were water scheduled (2 hours per day) and trained in an automatized T-maze (MazeEngineers, Skokie, Illinois, United States of America) to a nonmatch to place task. Briefly, each trial was...
Visual-stimuli Four-arm Maze test to Assess Cognition and Vision in Mice
Jean-Philippe Vit, Dieu-Trang Fuchs, Ariel Angel et al.
The prototype used to collect the present data shares the same specifications (including the color LED lights) with the now commercially available ViS4M manufactured by Maze Engineers.
Visual-stimuli Four-arm Maze test to Assess Cognition and Vision in Mice. Bio Protoc. 2021 Nov 20;11(22):e4234. PMID: 34909455; PMCID: PMC8635852
Vit JP, Fuchs DT, Angel A et al.
The prototype used to collect the present data shares the same specifications (including the color LED lights) with the now commercially available ViS4M manufactured by Maze Engineers.
Developmental cannabidiol exposure increases anxiety and modifies genome-wide brain DNA methylation in adult female mice. Clin Epigenet
Wanner, N.M., Colwell, M., Drown et al.
...novel areas. Mice were placed at the end of one arm facing the center in a standard Y-maze (MazeEngineers, Boston, MA) consisting of a high-walled chamber with three arms connected at 120°. Investigators...
Developmental cannabidiol exposure increases anxiety and modifies genome-wide brain DNA methylation in adult female mice
Nicole M Wanner, Mathia Colwell, Chelsea Drown et al.
...novel areas. Mice were placed at the end of one arm facing the center in a standard Y-maze (MazeEngineers, Boston, MA) consisting of a high-walled chamber with three arms connected at 120°. Investigators...
Attenuated dopamine signaling after aversive learning is restored by ketamine to rescue escape actions
Mingzheng Wu, Samuel Minkowicz, Vasin Dumrongprechachan et al.
...0.3 mA, 3 s; random 1–15 s inter-shock intervals). Active/Passive Avoidance Shuttle Boxes from MazeEngineers (Boston, MA) were used for the experiment. To assess the degree of aversive learning, test...
Making 'Good' Choices: Social Isolation in Mice Exacerbates the Effects of Chronic Stress on Decision Making
Arish, M. R., Tong Michelle, T. T.
...socially-housed groups. All mice were habituated to the experimenter and to the T-maze apparatus (Maze Engineers, Boston, MA; stem 30 × 10 cm, arm length 30 cm each) used for the CBC test at the beginning of...
(S)-5-(2'-Fluorophenyl)-N,N-dimethyl-1,2,3,4-tetrahydronaphthalen-2-amine, a Serotonin Receptor Modulator, Possesses Anticonvulsant, Prosocial, and Anxiolytic-like Properties in an Fmr1 Knockout Mouse Model of Fragile X Syndrome and Autism Spectrum Disorder
Jessica L Armstrong, Austen B Casey, Tanishka S Saraf et al.
Y-Maze (Maze Engineers, single arm dimensions 2.75 in. x 13.75 in. x 8 in.)
Current protocols in neuroscience2020
Assaying Fear Memory Discrimination and Generalization: Methods and Concepts
Hadley C Bergstrom
...fear conditioning systems available, including (Coulbourn Instruments, Whitehall PA, USA), MazeEngineers, (Boston MA, USA), Med Associates (St. Albans, VT USA), Stoelting Ugo Basile (Wood Dale, IL USA),...
The effects of age, sex, and handling on behavioral parameters in the multivariate concentric square fieldâ„¢ test
Jonathan Kent Gore-Langton, David Francis Werner, Linda Patia Spear
...consists of a square field (72 X 72 cm) surrounded by outer walls with a height of 25-28 cm (Maze Engineers; Boston, MA). The middle of the apparatus contains a central square arena (40 X 40 cm) that is...
Abrogation of atypical neurogenesis and vascular-derived EphA4 prevents repeated mild TBI-induced learning and memory impairments. Sci Rep
Greer, K., Basso, E.K.G., Kelly et al.
...for learning and memory utilizing the Barnes Maze (92 cm diameter, 20 holes, 5 cm holes) (Maze Engineers, Boston, MA USA) and the Ethovision XT software (Noldus, Leesburg, VA USA) at the same time each...
Abrogation of atypical neurogenesis and vascular-derived EphA4 prevents repeated mild TBI-induced learning and memory impairments
Kisha Greer, Erwin Kristobal Gudenschwager Basso, Colin Kelly et al.
...for learning and memory utilizing the Barnes Maze (92 cm diameter, 20 holes, 5 cm holes) (Maze Engineers, Boston, MA USA) and the Ethovision XT software (Noldus, Leesburg, VA USA) at the same time each...
I. Antidepressants and sexual behavior: Weekly ketamine injections increase sexual behavior initially in female and male rats
Guarraci, F. A., Ali, M., Gonzalez, C. M. et al.
Glia2020
Conditional depletion of Fus in oligodendrocytes leads to motor hyperactivity and increased myelin deposition associated with Akt and cholesterol activation
Kelly M Guzman, Lauren E Brink, Guillermo Rodriguez-Bey et al.
...a dark (enclosed side) connected by a small hole to allow the mouse to travel between each side (Maze Engineers). The mouse was placed in the dark side and movements were recorded using an overhead camera with...
Estrogen Withdrawal Increases Postpartum Anxiety via Oxytocin Plasticity in the Paraventricular Hypothalamus and Dorsal Raphe Nucleus
Hedges VL, Heaton EC, Amaral C et al.
bioRxiv2020
Microglia-targeted dendrimer-2PMPA therapy robustly inhibits GCPII and improves cognition in a mouse model of multiple sclerosis
Hollinger, K., Sharma, A., Tallon, C. et al.
...Briefly, mice were placed in the center of the maze (Maze Engineers, Glenview, IL) and trained to find a hidden target platform for 2 trials per day over 4 consecutive days...
Biorxiv_fulltext
Cell reports2020
Social Behavior Is Modulated by Valence-Encoding mPFC-Amygdala Sub-circuitry
Wen-Chin Huang, Aya Zucca, Jenna Levy et al.
...assay, a mouse connected to optic fibers habituated to a custom two/three-chamber apparatus (MazeEngineers, Boston, MA, USA) in the three-chamber configuration for 5 minutes. Immediately following the...
Surgery, Anesthesia and Intensive Care Environment Induce Delirium-Like Behaviors and Impairment of Synaptic Function-Related Gene Expression in Aged Mice. Frontiers in Aging Neuroscience
Illendula, M., Prasad, O. H., Bianca, F. et al.
Mice were allowed to explore a 40 × 40 × 40 cm box (MazeEngineers, United States) for 5 min.
PMC Full Text
Frontiers in aging neuroscience2020
Surgery, Anesthesia and Intensive Care Environment Induce Delirium-Like Behaviors and Impairment of Synaptic Function-Related Gene Expression in Aged Mice
Meghana Illendula, Hari Prasad Osuru, Bianca Ferrarese et al.
...test (OFT) was adapted from previous studies. Mice were allowed to explore a 40 × 40 × 40 cm box (MazeEngineers, United States) for 5 min. The total distance traveled by each mouse was used to evaluate mice’...
Social Isolation Induced Behavioural and Microstructural Differences in Juvenile Mice
Irwin, S.
Hippocampus2020
Dorsal hippocampus not always necessary in a radial arm maze delayed win-shift task
Layfield, D., Sidell, N., Abdullahi, A. et al.
Training took place on a custom automated radial maze (Maze Engineers, Cambridge, MA) with a 33.2 cm wide hub and pneumatic drop doors at the entrances to the 8 arms, each measuring 48.26 cm long, 10.79 cm wide with 20.95 cm tall walls.
Preprint
PloS One2020
Optimization and validation of a modified radial-arm water maze protocol using a murine model of mild closed head traumatic brain injury
Macheda T, Roberts KN, Morganti JM et al.
...RAWM test was performed in a circular pool (diameter = 121 cm, depth 75 cm, Fig 1A and 1B) (MazeEngineers, Boston, MA). A base (9 cm high), and an 8-shaped platform were added to the pool and eight...
Prion protein lowering is a disease-modifying therapy across prion disease stages, strains and endpoints, Nucleic Acids Research, 48(19) 10615'10631
Minikel, E. V., Zhao, H. T., Le, J. et al.
Mice were seated on a rod rotating at 4 rpm in a six-lane Rotarod apparatus (Maze Engineers).
PMC Full Text
Nucleic acids research2020
Prion protein lowering is a disease-modifying therapy across prion disease stages, strains and endpoints
Eric Vallabh Minikel, Hien T Zhao, Jason Le et al.
Six-lane Rotarod apparatus (Maze Engineers)
University of Toronto2020
Efficacy of ?-amyloid Attenuation Depends on Regional and Temporal Progression of Alzheimer's Disease
Morrone, C. D.
A circular field (Maze Engineers) was used (20 holes, one is the escape box).
PMC Full Text
Oxford Academic2020
Regional differences in Alzheimer's disease pathology confound behavioural rescue after amyloid-? attenuation, Brain
Morrone, C.D., Bazzigaluppi, P., Beckett, T.L. et al.
A circular field (Maze Engineers) was used (20 holes, one is the escape box).
PMC Full Text
Brain : a journal of neurology2020
Regional differences in Alzheimer's disease pathology confound behavioural rescue after amyloid-β attenuation
Christopher D Morrone, Paolo Bazzigaluppi, Tina L Beckett et al.
A circular field (Maze Engineers) was used (20 holes, one is the escape box)
Universidade Federal do Cear�2020
Parkinsonismo Experimental Induzido por Rotenona em Ratos: Um Estudo Temporal de Altera''es Motoras e n'o Motoras e Mecanismos Envolvidos. Faculdade de Medicina
Nascimento, T. S.
Fonte: Maze Engineers and Noldus
Dissertation
Scholar Commons2020
A Behavioral and Voltammetric Study of the Effects of Pb Exposure in Mice as a Model of Autism Spectrum Disorder. The University of South Carolina
Parke, B
An elevated zero apparatus was used from Maze Engineers (Boston, MA).
Dissertation
ScienceDirect2020
Perreault, S. T., Christie, B. R. Hippocampal cognitive impairment in juvenile rats after repeated mild traumatic brain injury. Behavioural Brain Research 387
Pinar, C., Trivino-Paredes, J., T.
Scientific Reports2020
Effects of cochlear hair cell ablation on spatial learning/memory
Qian, Z. J., Ricci, A. J.
...light cycle.
Spatial learning/memory was assayed using an automated 8 arm radial maze (Fig. 3a; MazeEngineers, Cambridge, MA, USA) integrated with EthoVision XT video tracking software (Noldus, Leesburg, VA,...
Prenatal alcohol exposure reduces posterior dorsomedial striatum excitability and motivation in a sex- and age-dependent fashion
Roselli, V., Guo, C., Huang, D. et al.
...respectively.
Open field test
The test chamber was 60 cm for both side-widths × 40cm in height (Maze Engineers) with a floor illumination at ~60–80 lux. Rats were placed in the peripheral area facing the...
TDP-43 mediated blood-brain barrier permeability and leukocyte infiltration promote neurodegeneration in a low-grade systemic inflammation mouse model
Zamudio, F., Loon, A.R., Smeltzer et al.
...and learning performance were assessed by placing mice onto an accelerating circular rod (Maze Engineers, Boston, MA, USA). The time until falling was recorded for each mouse. Mice were given four...
Tip60 protects against amyloid-β-induced transcriptomic alterations via different modes of action in early versus late stages of neurodegeneration
Haolin Zhang, Haolin Zhang, Bhanu Chandra Karisetty et al.
...assay was performed as described with minor revisions. The T-maze equipment was purchased from MazeEngineers (Boston, MA, USA). We trained the flies by electroshock consisting of twelve 3.75-second pulses...
Transcriptome analysis uncovers distinct modes of epigenetic gene changes in early versus late stages of amyloid-? induced Alzheimer's disease pathology
Zhang, H., Karisetty, C.B., Bhatnagar, A. et al.
The T-maze equipment was purchased from MazeEngineers (Boston, MA, USA).
Preprint
International Journal of Comparative Psychology2019
Drinks Like a Fish: Neural Maturation Mitigates the Effects of Ethanol on Associative Learning in Zebrafish (Danio rerio)
Fort, T. D, Negley, J., Mcewen, T.
Pharmacology, biochemistry, and behavior2019
Differential expression of nicotine withdrawal as a function of developmental age in the rat
Robin J Keeley, Tom E Mayer, Li-Ming Hsu et al.
custom-made opaque Plexiglas conditioning chambers (Maze Engineers, Glenview, IL, USA)
Molecular Neurodegeneration2019
Autophagy protein NRBF2 has reduced expression in Alzheimer's brains and modulates memory and amyloid-beta homeostasis in mice. Mol Neurodegeneration
Lachance, V., Wang, Q., Sweet, E. et al.
The Y-Maze (Maze Engineers) consisted of three gray acrylic closed arms measuring 35 cm L × 5 cm W × 20 cm H.
PMC Full Text
Molecular neurodegeneration2019
Autophagy protein NRBF2 has reduced expression in Alzheimer's brains and modulates memory and amyloid-beta homeostasis in mice
The Y-Maze (Maze Engineers) consisted of three gray acrylic closed arms measuring 35 cm L x 5 cm W x 20 cm H
ProQuest2019
Antioxidant Enzyme Targeting to ICAM-1 Improves Outcomes following Experimental Traumatic Brain Injury. Temple University
Mitchel, L. E.
Genes, brain, and behavior2019
Genetic background modifies CNS-mediated sensorimotor decline in the AD-BXD mouse model of genetic diversity in Alzheimer's disease
Kristen M S O'Connell, Andrew R Ouellette, Sarah M Neuner et al.
...mouse in the center of a 1 m long beam 12 mm wide that was elevated 50 cm above a table surface (Maze Engineers, Boston, Massachusetts). The time taken in seconds for each mouse to cross the beam to a safe...
Genetic background modifies CNS-mediated sensorimotor decline in the AD-BXD mouse model of genetic diversity in Alzheimer's disease. Genes, Brain and Behavior, 18(8), e12603
Ouellette, A. R., Neuner, S. M., Dunn, A. R. et al.
...mouse in the center of a 1 m long beam 12 mm wide that was elevated 50 cm above a table surface (Maze Engineers, Boston, Massachusetts). The time taken in seconds for each mouse to cross the beam to a safe...
Effects of the second-generation "bath salt" cathinone alpha-pyrrolidinopropiophenone (?-PPP) on behavior and monoamine neurochemistry in male mice. Psychopharmacology 236, 1107'1117
Ray, A., Chitre, N.M., Daphney et al.
Performance in the Y-maze was assessed by both automated quantitation (Maze Engineers; Cambridge, MA) and manual observation.
PMC Full Text
Virginia Tech2019
Geer. K. M. Aberrant hippocampal neurogenesis contributes to learning and memory deficits in a mouse model of repetitive mild traumatic brain injury
Mice were evaluated for learning and memory utilizing the Barnes Maze (92 cm diameter, 20 holes, 5 cm holes) (Maze Engineers, Boston, MA USA) and the Ethovision XT software (Noldus, Leesburg, VA USA)...
PMC Full Text
Scholar Commons2019
Ultra-Fast Sensors to Study the Fundamental Neurochemistry Underlying Disease. University of South Carolina
West, A.
An elevated zero apparatus was used from Maze Engineers (Boston, MA).
Dissertation
Cell2018
Dissociable Structural and Functional Hippocampal Outputs via Distinct Subiculum Cell Classes
Cembrowski, M. S., Phillips, M. G., DiLisio S. F. et al.
eNeuro2018
Behavioral Phenotyping of an Improved Mouse Model of Phelan-McDermid Syndrome with a Complete Deletion of the Shank3 Gene
Elodie Drapeau, Mohammed Riad, Yuji Kajiwara et al.
...holes evenly spaced around the edge of a brightly-lit 100 cm in diameter circular arena (Maze Engineers). While most of the holes (nontarget) have nothing beneath them and lead nowhere, the target...
The Behavioral Effects of Oral Psychostimulant Ingestion on a Laboratory Rat Sample: An Undergraduate Research Experience. Journal of
Howerter, D. D., Larson, J. G., Hill, E. M.
Purchased commercially, the acquisition of a simple EPM, designed for rat use, as described previously, would cost a university department approximately $2,200.00 (based on pricing information from Maze Engineers, Braintree Scientific Inc., Stoelting, and Kinder Scientific).
Reward behaviour is regulated by the strength of hippocampus-nucleus accumbens synapses
Tara A LeGates, Mark D Kvarta, Jessica R Tooley et al.
Three-chamber CPP Arena (Maze Engineers)
PLOS One2018
Repeated mild traumatic brain injury can cause acute neurologic impairment without overt structural damage in juvenile rats
Meconi, A., Wortman, R.C., Wright, D.K. et al.
...maze
The Barnes maze was used to assess spatial memory after injury. The Barnes maze (Maze Engineers, Cambridge, MA) is an elevated circular platform (122 cm diameter) with 20 holes (10cm diameter)...
S., An Evaluation of Alzheimer's Disease-related Pathology in Two Different Models of Diabetes in Immune-challenged Mice. University of Navada, Las Vegas Theses, Dissertations, Professional Papers, and Capstones. 3370
Murtishaw, A
The maze, made of white, circular plastic (92 cm diameter) with a black false bottom, was purchased from Maze Engineers (Glenview, IL).
Dissertation
Psychopharmacology2018
Effects of the second-generation "bath salt" cathinone alpha-pyrrolidinopropiophenone (α-PPP) on behavior and monoamine neurochemistry in male mice
Azizi Ray, Neha Milind Chitre, Cedrick Maceo Daphney et al.
...lasted for 10 minutes. Performance in the Y-maze was assessed by both automated quantitation (Maze Engineers; Cambridge, MA) and manual observation. Spontaneous alternations were calculated as the...
Proceedings of the National Academy of Sciences of the United States of America2017
Rhythmic brain stimulation reduces anxiety-related behavior in a mouse model based on meditation training
Aldis P Weible, Denise M Piscopo, Mary K Rothbart et al.
Light/Dark Box apparatus, 40 cm x 40 cm x 34.5 cm (Maze Engineers)
Title
Product
Journal
Year
Astrocytic PERK Deficiency Drives Prefrontal Circuit Dysfunction and Depressive-Like Behaviors.
Kai Chen, Riya Gupta et al.
Fear Conditioning
Advanced Science
2026
When Familiar Faces Feel Better: A Framework for Social Neurocognitive Aging in a Rat Model.
Subhadeep Dutta Gupta, Jeffrey M Long et al.
Sociability Chamber
eneuro
2026
Acetyl-carnitine improves hyperactivity and learning deficits in <i>KAT6A</i> haploinsufficient mice.
Samantha Eccles, Hannah K Vanyai et al.
Barnes Maze
Life Science Alliance
2026
MCD enzyme deficiency drives early mortality and multiorgan metabolic disruption in Dahl salt-sensitive rats.
Olha Kravtsova, Yifan Tan et al.
Treadmill
iScience
2026
APP-mediated intracellular signaling rescues sleep impairment and blood-brain barrier leakage in Alzheimer's disease mouse model.
Clémentine Puech, Anjana Sadanand et al.
Elevated Plus Maze
Alzheimer's & Dementia
2026
Furosemide prevents noise-induced hearing loss and enhances the preventive effect of N-acetylcysteine.
Hongguo Su, Fan Wu et al.
Startle Response System
Hearing Research
2026
The E-Protein Daughterless Regulates Olfactory Learning of Adult Drosophila melanogaster.
Laura Tamberg, Carl Sander Kiir et al.
T - Maze
eneuro
2026
Genetic depletion of the early autophagy protein ATG13 impairs mitochondrial energy metabolism, augments oxidative stress, induces the polarization of macrophages to the M1 inflammatory mode, and compromises myelin integrity in skeletal muscle.
Mubaraq A Toriola, Emma Timlin et al.
Grip Strength Meter
Inflammation Research
2026
Pathological gain-of-function human variants in the GRIK2 kainate receptor gene cause wide-ranging behavioral dysfunction and seizures in mouse models.
Brynna T Webb, Hieu Trinh et al.
Automated T Maze
Neurobiology of Disease
2026
Doxazosin Alleviates Chronic Orofacial Pain
Karin N. Westlund, Bingye Xue et al.
Elevated Plus Maze
International Journal of Molecular Sciences
2026
Development of visual-stimulus reversal learning-memory in mice is dependent on social interaction.
Sarah Wicki, Annika Canziani et al.
Attentional Set Shifting Chamber
iScience
2026
0.33<i>g</i> mitigates muscle atrophy while 0.67<i>g</i> preserves muscle function and myofiber type composition in mice during spaceflight.
Ryosuke Tsuji, Ryo Fujita et al.
Grip Strength Meter
Science Advances
2026
Analysis of Behavioral Characteristics by Population Size in Ornamental Fish: A Video Tracking-Based Experimental Study.
Jong-Mo Seo, Seung-Bin Heo et al.
ConductVision
2025 Korean Society of Environmental Biology (KOSEB) Annual Conference Proceedings
2025
The Impact of Rosemary and Ginger Extracts on Aging and Healthspan in Drosophila.
Ricardo Aparicio, Anna M Salazar et al.
Active/Passive Avoidance Shuttle Box
aging and disease
2025
Clearance of intracranial debris by ultrasound reduces inflammation and improves outcomes in hemorrhagic stroke models.
Matine M Azadian, Sepideh Kiani Shabestari et al.
Grip Strength Meter
Nature Biotechnology
2025
Depending on intensity, exercise improved or worsened pathology in a model of prodromal Parkinson's disease.
Leonie Baldauf, Malte Feja et al.
Treadmill
npj Parkinson's Disease
2025
Experimental Galactose-1-Phosphate Uridylyltransferase (GALT) mRNA Therapy Improves Motor-Related Phenotypes in a Mouse Model of Classic Galactosemia-A Pilot Study.
Olivia Bellagamba, Aaron J Guo et al.
Rotarod Test
Biomedicines
2025
MICU2 controls mitochondrial calcium signaling and migration in neurons during development.
Elena Berezhnaya, Benjamín Cartes-Saavedra et al.
Rotarod Test
Cell Reports
2025
Representations of stimulus features in the ventral hippocampus.
Jeremy S Biane, Max A Ladow et al.
Elevated Plus Maze
Neuron
2025
Longitudinal characterization reveals behavioral impairments in aged APP knock in mouse models
Lisa Blackmer-Raynolds, Lyndsey D Lipson et al.
Barnes Maze
Scientific Reports
2025
22 and 50 kHz rat ultrasonic vocalization playback reveals sex differences in behavior and cFos in brain regions associated with affective processing.
Sydney M Bonauto, Kaya A Patel et al.
Open Field Test
Behavioural Brain Research
2025
Pretreatment of Mice with 830 nm Light Enhances Endurance During Acute Exercise.
Nashwa Cheema, Namrata Ghag et al.
Treadmill
Muscles
2025
Moderate Chronic Treadmill Exercise Slows Dopaminergic Neuron Loss in a Rat Model of Parkinson's Disease and Alters RNA Content of Circulating Plasma Exosomes
Bruce A Citron, Maynard Guzman et al.
Treadmill
Journal of neuroscience research
2025
Chronic Alcohol Drinking Impairs Recognition Memory And Insulin-Associated Genes In The Medial Prefrontal Cortex.
Bryan Cruz, Michela Palmisano et al.
Automated Radial Arm Maze
Molecular Neurobiology
2025
Protective exercise responses in the dentate gyrus of Alzheimer's disease mouse model revealed with single-nucleus RNA-sequencing.
Joana F da Rocha, Michelle L Lance et al.
Fear Conditioning
Nature Neuroscience
2025
Therapeutic Treatment With OLX-07010 Inhibited Tau Aggregation and Ameliorated Motor Deficits in an Aged Mouse Model of Tauopathy
E J Davidowitz, P Lopez et al.
Rotarod Test
Journal of neurochemistry
2025
Central biogenic amine deficiency with concomitant exploratory behavioral deficits in Dnajc12 knock-out mice
Isaac Bul Deng, Jordan Follett et al.
Grip Strength Meter
NPJ Parkinson's disease
2025
Cellular and circuit features distinguish mouse dentate gyrus semilunar granule cells and granule cells activated during contextual memory formation
Laura Dovek, Mahboubeh Ahmadi et al.
Barnes Maze
eLife
2025
Spatial navigation entropy suggests allocentric dysfunction in PPPD
Inhibition of Rho-Associated Kinases ROCK1 and ROCK2 as a Therapeutic Strategy to Reactivate the Repressed <i>FXN</i> Gene in Friedreich Ataxia.
Minggang Fang, Shahid Banday et al.
Rotarod Test
The Journal of Neuroscience
2025
Behavioral Physiology of the CNTNAP2 Knockout Mouse
Tanya Gandhi, Charles C Lee
Open Field Test
HSOA trends in anatomy and physiology
2025
Complementary roles of dorsal and ventral hippocampus in the flexible adaptation of goal-directed behavior.
Maryam Hasantash, Yifei Li et al.
Barnes Maze
Science Advances
2025
Food reward entrainment increases mealtime anxiety in goldfish via a ghrelin-dependent mechanism
Lisbeth Herrera-Castillo, Nuria Saiz et al.
Light Dark Box
Scientific Reports
2025
A novel CD71 Centyrin:Gys1 siRNA conjugate reduces glycogen synthesis and glycogen levels in a mouse model of Pompe disease.
Bryce D Holt, Samuel J Elliott et al.
Rotarod Test
Molecular Therapy
2025
Accurate Tracking of Locomotory Kinematics in Mice Moving Freely in Three-Dimensional Environments
Bogna M Ignatowska-Jankowska, Lakshmipriya I Swaminathan et al.
Treadmill
eNeuro
2025
Presymptomatic targeted circuit manipulation for ameliorating Huntington's disease pathogenesis
Ebenezer C Ikefuama, Ashley N Slaviero et al.
Active/Passive Avoidance Shuttle Box
iScience
2025
Growth hormone-deficient Ames dwarf mice resist sarcopenia and exhibit enhanced endurance running performance at 24 months
Matthew J Johnston, Sharlene G Rakoczy et al.
Grip Strength Meter
GeroScience
2025
Conditional Dmd ablation in muscle and brain causes profound effects on muscle function and neurobehavior.
Muthukumar Karuppasamy, Katherine G English et al.
T - Maze
Communications Biology
2025
Magel2 in hypothalamic POMC neurons influences the impact of stress on anxiety-like behavior and spatial learning associated with a food reward in male mice.
Sangbhin Lee, Young-Hwan Jo
Open Field Test
Frontiers in Neural Circuits
2025
Targeting microRNA-dependent control of X chromosome inactivation improves the Rett Syndrome phenotype
Song Lou, Rachisan DJiake Tihagam et al.
Rotarod Test
Nature Communications
2025
A Protocol to Assess Time-of-Day-Dependent Learning and Memory in Mice Using the Novel Object Recognition Test
Jordan Mar, Matthew A McGregor et al.
Open Field Test
Bio-protocol
2025
Pathogenic variants in SMARCA1 cause an X-linked neurodevelopmental disorder modulated by NURF complex composition.
Ghayda M Mirzaa, Keqin Yan et al.
Morris Water Maze
Nature Communications
2025
A novel gene edited rat model of cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy (CARASIL).
Brittany Monte, Judianne Davis et al.
Open Field Test
Cerebral Circulation - Cognition and Behavior
2025
Autophagic impairment in sleep-wake circuitry is linked to sleep loss at the early stages of Alzheimer's disease
Christopher Daniel Morrone, Arielle A Tsang et al.
Barnes Maze
Molecular neurodegeneration
2025
Reduced IGF-1 signaling fails to limit Alzheimer's disease progression in a novel rat model of IGF-1R haploinsufficiency.
Sushma Narayan, Kai Mao et al.
Open Field Test
Scientific Reports
2025
Genetically diverse mice exhibit divergent domain-specific, sex-dependent behavioral outcomes following exposure to early life stress
Jennifer Nguyen, Kevin Shimizu et al.
Elevated Plus Maze
PloS one
2025
Cognitive Function, Sleep, and Neuroinflammatory Markers in Mice Exposed to Very Long-Term Intermittent Hypoxia
Clementine Puech, Mohammad Badran et al.
Open Field Test
International journal of molecular sciences
2025
AAV delivery of full-length SYNGAP1 rescues epileptic and behavioral phenotypes in a mouse model of SYNGAP1-related disorders.
Meagan A Quinlan, Rong Guo et al.
Open Field Test
Molecular Therapy
2025
Behavioral phenotyping identifies autism-like repetitive stereotypies in a Tsc2 haploinsufficient rat model
Antonia Ramme, Mirjam Zachow et al.
Morris Water Maze
Behavioral and brain functions : BBF
2025
Evaluation of the Therapeutic Potential of Synthetic Growth Hormone-Releasing Hormone Antagonist MIA-690 as a Cognitive Modulator in a Mouse Model of Gulf War Illness
Luis Manuel Salgueiro-Tosta, Arumugam Radhakrishnan Jayakumar et al.
Morris Water Maze
International journal of molecular sciences
2025
5xFAD mutations induce hearing impairment in the Ahl-corrected 5xFAD mice.
Hongguo Su, Fan Wu et al.
Startle Response System
Experimental Neurology
2025
Vasoactive neuropeptide dysregulation: A novel mechanism of microvascular dysfunction in vascular cognitive impairment.
Willians Tambo, Keren Powell et al.
Y Maze
Alzheimer's & Dementia
2025
Opposing roles of microglial and macrophagic C3ar1 signaling in stress-induced synaptic and behavioral changes
Ashutosh Tripathi, Alona Bartosh et al.
Y Maze
Molecular psychiatry
2025
Photobiomodulation Strengthens Muscles via Its Dual Functions in Gut Microbiota.
Prabhat Upadhyay, Asmita Banstola et al.
Treadmill
Advanced Science
2025
Hyperhomocysteinemia-induced VCID results in visual deficits, reduced neuroinflammation and vascular alterations in the retina
Erica M Weekman, Colin B Rogers et al.
Visual X Maze
Journal of neuroinflammation
2025
mWAKE in the Central Amygdala Regulates Fear Learning and Memory
Jiali Xiong, Anuradha Mehta et al.
Fear Conditioning
The Journal of neuroscience : the official journal of the Society for Neuroscience
2025
An AIM2 inflammasome biomimetic mineralization inhibitor for vascular dementia therapy
Yueqi Zhang, Lixian Jiang et al.
Barnes Maze
Theranostics
2025
Dietary fiber modulates gut microbiota and lipid metabolism ameliorating Alzheimer's pathology in 5xFAD mice.
Yuhai Zhao, Christopher M Taylor et al.
Open Field Test
Scientific Reports
2025
Profiling of research domain criteria-based behaviors following single prolonged stress in male C57BL/6J mice.
Krysten P O'Hara, Savanna M King et al.
Elevated Plus Maze
Stress
2025
Asymmetric Dimethylarginine Disrupts Tumor Antigen Presentation in Breast Cancer.
Mei Li, Yi-Ling Chen et al.
Flow Cytometer
International Journal of Molecular Sciences
2025
Electric field stimulation directs target-specific axon regeneration and partial restoration of vision after optic nerve crush injury.
Timothy Kim, Ege Iseri et al.
Open Field Test
PLOS ONE
2025
Inhibition of GSK3α,β rescues cognitive phenotypes in a preclinical mouse model of CTNNB1 syndrome
Jonathan M Alexander, Leeanne Vazquez-Ramirez et al.
Rotarod Test
EMBO molecular medicine
2024
Quantification of nutrient fluxes during acute exercise in mice.
Jessie Axsom, Tara TeSlaa et al.
Treadmill
Cell Metabolism
2024
A bespoke water T-maze apparatus and protocol: an optimized, reliable, and repeatable method for screening learning, memory, and executive functioning in laboratory mice
Jeremy Davidson Bailoo, Susan E Bergeson et al.
T - Maze
Frontiers in behavioral neuroscience
2024
Increased regional activity of a pro-autophagy pathway in schizophrenia as a contributor to sex differences in the disease pathology
Kathryn J Bjornson, Amanda M Vanderplow et al.
Open Field Test
Cell reports. Medicine
2024
Serotonin as a biomarker of toxin-induced Parkinsonism
Anna Marie Buchanan, Sergio Mena et al.
Elevated Zero Maze
Molecular medicine (Cambridge, Mass.)
2024
Cardiac NAD<sup>+</sup> depletion in mice promotes hypertrophic cardiomyopathy and arrhythmias prior to impaired bioenergetics.
Khanh V Doan, Timothy S Luongo et al.
Treadmill
Nature Cardiovascular Research
2024
Comparative effect of atorvastatin and risperidone on modulation of TLR4/NF-κB/NOX-2 in a rat model of valproic acid-induced autism
Eman A E Farrag, Mona H Askar et al.
Light Dark Box
Behavioral and brain functions : BBF
2024
Intermittent cytomegalovirus infection alters neurobiological metabolism and induces cognitive deficits in mice
Harrison, M. A., Morris, S. L. et al.
Active/Passive Avoidance Shuttle Box
Brain, Behavior, and Immunity
2024
Early adversity causes sex-specific deficits in perforant pathway connectivity and contextual memory in adolescent mice
Rafiad Islam, Jordon D White et al.
Open Field Test
Biology of sex differences
2024
Schwann cell-secreted PGE<sub>2</sub> promotes sensory neuron excitability during development.
Husniye Kantarci, Pablo D Elvira et al.
Horizontal Ladder
Cell
2024
Prophylactic senolytic treatment in aged mice reduces seizure severity and improves survival from Status Epilepticus
Tahiyana Khan, Abbas I Hussain et al.
Barnes Maze
Aging cell
2024
Neuronal Ensembles in the Amygdala Allow Social Information to Motivate Later Decisions
Henry W Kietzman, Gracy Trinoskey-Rice et al.
Sociability Chamber
The Journal of neuroscience : the official journal of the Society for Neuroscience
2024
FDA-approved cannabidiol [Epidiolex®] alleviates Gulf War Illness-linked cognitive and mood dysfunction, hyperalgesia, neuroinflammatory signaling, and declined neurogenesis
Maheedhar Kodali, Leelavathi N Madhu et al.
Von Frey Apparatus
Military Medical Research
2024
Methylphenidate differentially affects the social ultrasonic vocalizations of wild-type and prodromal Parkinsonian rats
Sarah A Lechner, Cynthia A Kelm-Nelson et al.
Open Field Test
Behavioral neuroscience
2024
In Vivo Evaluation of Nose-to-Brain Delivery of Liposomal Donepezil, Memantine, and BACE-1 siRNA for Alzheimer's Disease Therapy
David Lee, Andrew M Shen et al.
Y Maze
International journal of molecular sciences
2024
A subset of dopamine receptor-expressing neurons in the nucleus accumbens controls feeding and energy homeostasis
Yiqiong Liu, Ying Wang et al.
Operant Conditioning Chamber
Nature metabolism
2024
Compensatory changes after spinal cord injury in a remyelination deficient mouse model
S B Manesh, B R Kondiles et al.
Treadmill
Journal of neurochemistry
2024
Behavioral, neurotransmitter and transcriptomic analyses in male and female Fmr1 KO mice
Deirdre M McCarthy, Cynthia Vied et al.
Sociability Chamber
Frontiers in behavioral neuroscience
2024
Autism-associated CHD8 controls reactive gliosis and neuroinflammation via remodeling chromatin in astrocytes.
Platon Megagiannis, Yuan Mei et al.
Open Field Test
Cell Reports
2024
Cognitive behavioral phenotyping of DSCAM heterozygosity as a model for autism spectrum disorder
Ryan C Neff, Katherine A Stangis et al.
Active/Passive Avoidance Shuttle Box
Genes, brain, and behavior
2024
Gastrointestinal nematode infection during pregnancy and lactation enhances spatial reference memory and reduces indicators of anxiety-like behaviour in uninfected adult female mouse offspring
Sophia Noel, Ryan LaFrancois et al.
Barnes Maze
Parasitology
2024
Prior Negative Experience Biases Activity of Medial Amygdala during Interstrain Social Engagement in Male Rats.
Alexandra C Ritger, Nimah M Rasheed et al.
Sociability Chamber
eneuro
2024
Gamma frequency connectivity in frontostriatal networks associated with social preference is reduced with traumatic brain injury
Morteza Salimi, Tianzhi Tang et al.
Sociability Chamber
Network neuroscience (Cambridge, Mass.)
2024
M2 receptors are required for spatiotemporal sequence learning in mouse primary visual cortex
Susrita Sarkar, Catalina Martinez Reyes et al.
Open Field Test
Journal of neurophysiology
2024
Accumulation of F-actin drives brain aging and limits healthspan in Drosophila
Edward T Schmid, Joseph M Schinaman et al.
Active/Passive Avoidance Shuttle Box
Nature Communications
2024
Cerebral Proteomic Changes in the rTg-D Rat Model of Cerebral Amyloid Angiopathy Type-2 With Cortical Microhemorrhages and Cognitive Impairments
Joseph M Schrader, Mark Majchrzak et al.
Automated Radial Arm Maze
Neuroscience insights
2024
Role of the prefrontal cortical protease TACE/ADAM17 in neurobehavioral responses to chronic stress during adolescence
Fransua Sharafeddin, Julio Sierra et al.
Y Maze
Brain and behavior
2024
Shifts in naturalistic behaviors induced by early social isolation stress are associated with adult binge-like eating in female rats
Timothy B Simon, Julio Sierra et al.
Y Maze
Frontiers in behavioral neuroscience
2024
A Real-Time Approach for Assessing Rodent Engagement in a Nose-Poking Go/No-Go Behavioral Task Using ArUco Markers
Thomas J Smith, Trevor R Smith et al.
Operant Conditioning Chamber
Bio-protocol
2024
PINK1 knockout rats show premotor cognitive deficits measured through a complex maze
Isabel Soto, Vicki A Nejtek et al.
Morris Water Maze
Frontiers in neuroscience
2024
ATP1A1-linked diseases require a malfunctioning protein product from one allele.
Kerri Spontarelli, Victoria C Young et al.
Rotarod Test
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
2024
Using a Combination of Novel Research Tools to Understand Social Interaction in the Drosophila melanogaster Model for Fragile X Syndrome
Maja Stojkovic, Milan Petrovic et al.
Open Field Test
Biology
2024
Using synchronized brain rhythms to bias memory-guided decisions
John J Stout, Allison E George et al.
Automated T Maze
eLife
2024
Nanoligomers targeting NF-κB and NLRP3 reduce neuroinflammation and improve cognitive function with aging and tauopathy
Devin Wahl, Sydney J Risen et al.
Grip Strength Meter
Journal of neuroinflammation
2024
Sex-specific effects of alcohol on neurobehavioral performance and endoplasmic reticulum stress: an analysis using neuron-specific MANF deficient mice
Wen Wen, Hui Li et al.
Balance Beam
Frontiers in pharmacology
2024
ASICs mediate fast excitatory synaptic transmission for tactile discrimination
Akihiro Yamada, Jennifer Ling et al.
Open Field Test
Neuron
2024
Offline ensemble co-reactivation links memories across days
Yosif Zaki, Zachary T Pennington et al.
Barnes Maze
Nature
2024
Prolactin Drives Iron Release from Macrophages and Uptake in Mammary Cancer Cells through CD44.
Reagan Farrell, Nicholas Pascuzzi et al.
Flow Cytometer
International Journal of Molecular Sciences
2024
Base editing rescue of spinal muscular atrophy in cells and in mice
Arbab, M., Matuszek, Z. et al.
Horizontal Grid Test
Science
2023
Solriamfetol enhances wakefulness and improves cognition and anxiety in a murine model of OSA
Badran, M., Puech, C. et al.
Forced Swim Test
Sleep Medicine
2023
Timing matters: Sex differences in inflammatory and behavioral outcomes following repetitive blast mild traumatic brain injury
Baskin, B. M., Logsdon, A. F. et al.
Elevated Zero Maze
Brain, Behavior, and Immunity
2023
University of Washington?ProQuest Dissertations Publishing, ?2023.?30246379
Baskin, Britahny M.? ?Central et al.
Weight Drop TBI Model
University of Washington?ProQuest Dissertations Publishing
2023
Influence of RVFV Infection on Olfactory Perception and Behavior in Drosophila melanogaster
Stella Bergmann, Maja C Bohn et al.
Y Maze
Pathogens (Basel, Switzerland)
2023
Stress-mediated dysregulation of the Rap1 small GTPase impairs hippocampal structure and function
Bjornson, K. J., Vanderplow, A. M. et al.
Open Field Test
IScience
2023
Identifying applications of virtual reality to benefit the stroke translational pipeline
Matan Bone, Maham Malik et al.
Morris Water Maze
Brain and neuroscience advances
2023
Decreased myelin-related gene expression in the nucleus accumbens during spontaneous neonatal opioid withdrawal in the absence of long-term behavioral effects in adult outbred CFW mice
Kristyn N Borrelli, Kelly K Wingfield et al.
Barnes Maze
Neuropharmacology
2023
Functional Dizziness as a Spatial Cognitive Dysfunction
et al. Serotonin as a biomarker of toxin-induced Parkinsonism
Buchanan, A.M., Mena, S. et al.
Elevated Zero Maze
Mol Med
2023
Heme-Induced Macrophage Phenotype Switching and Impaired Endogenous Opioid Homeostasis Correlate with Chronic Widespread Pain in HIV
Chatterjee, T., Arora, I. et al.
Hot Plate or Hot/Cold Plate
Cells
2023
High Heme and Low Heme Oxygenase-1 Are Associated with Mast Cell Activation/Degranulation in HIV-Induced Chronic Widespread Pain
Chatterjee, T., Arora, I. et al.
Hot Plate or Hot/Cold Plate
Antioxidants
2023
Paraventricular Thalamic MC3R Circuits Link Energy Homeostasis with Anxiety-Related Behavior
Dajin Cho, Kyle O'Berry et al.
Elevated Zero Maze
The Journal of neuroscience : the official journal of the Society for Neuroscience
2023
Intergenerational arsenic exposure on the mouse epigenome and metabolic physiology
Mathia L Colwell, Nicole Flack et al.
Y Maze
Environmental and molecular mutagenesis
2023
Greally, Masako Suzuki, Marija Kundakovic. Early-life stress and ovarian hormones alter transcriptional regulation in the nucleus accumbens resulting in sex-specific responses to cocaine
Devin Rocks, Ivana Jaric et al.
Conditioned Place Preference Chamber
bioRxiv
2023
Assessment of pain-related behaviors in HIV-1 transgenic rats as a model of HIV-associated chronic pain
E Gryshyna, A., Chatterjee, T. et al.
Hot Plate or Hot/Cold Plate
Molecular Pain
2023
Role of Dopamine Neurons in Familiarity
Fleury, S., Kolaric, R. et al.
Open Field Test
bioRxiv
2023
Estradiol withdrawal following a hormone simulated pregnancy induces deficits in affective behaviors and increases ?FosB in D1 and D2 neurons in the nucleus accumbens core in mice
Foster, W. B., Beach, K. F. et al.
Elevated Plus Maze
Hormones and Behavior
2023
An updated Barnes maze protocol for assessing the outcome of controlled cortical impact mouse models of traumatic brain injury
Gee, C. C., Steffen, R. et al.
Barnes Maze
Journal of Neuroscience Methods
2023
2MDR, a Microcomputer-Controlled Visual Stimulation Device for Psychotherapy-Like Treatments of Mice
Isa Jauch, Jan Kamm et al.
Fear Conditioning
ENeuro
2023
"Baf155 regulates skeletal muscle metabolism via HIF-1a signaling"
Kang JS, Kim D et al.
Treadmill
PLoS BioL
2023
Young, Ryan Sweazey, Alexandria Padro, Jeannie Lee, Tulio Bueso, Roberto M. Hernandez, Jongyeol Kim, Alexander Katz, Francis Rossignol, Clesson Turner, Caralynn M. Wilczewski, George L. Maxwell, Miguel Holmgren, Jeremy D. Bailoo, Sho T. Yano, Pablo Artigas. ATP1A1-linked diseases require a malfunctioning protein product from one allele
Kerri Spontarelli, Victoria C.
Rotarod Test
Biorxiv
2023
Disruptive lysosomal-metabolic signaling and neurodevelopmental deficits that precede Purkinje cell loss in a mouse model of Niemann-Pick Type-C disease
Kim, S., Ochoa, K. et al.
Horizontal Ladder
Scientific Reports
2023
Chronic pharmacological activation of SERCA with CDN1163 affects spatial cognitive flexibility but not attention and impulsivity in mice
Benjamin Klocke, Carter Moore et al.
Morris Water Maze
Behavioural pharmacology
2023
(S)-Ketamine but Not (R)-Ketamine Shows Acute Effects on Depression-Like Behavior and Sleep-Wake Architecture in Rats
The international journal of neuropsychopharmacology
2023
Social defeat stress induces genome-wide 5mC and 5hmC alterations in the mouse brain
Kuehner, J. N., Walia, N. R. et al.
Open Field Test
G3 Genes|Genomes|Genetics
2023
Predictors of prodromal Parkinson's disease in young adult Pink1?/? rats
Lechner, S. A., Welsch, J. M. et al.
Open Field Test
Frontiers in Behavioral Neuroscience
2023
Supraphysiologic doses of 17β-estradiol aggravate depression-like behaviors in ovariectomized mice possibly via regulating microglial responses and brain glycerophospholipid metabolism.
Ming Li, Jing Zhang et al.
Open Field Test
Journal of Neuroinflammation
2023
A small molecule ligand for the novel pain target, GPR171, produces minimal reward in mice. Pharmacology Biochemistry and Behavior
McDermott, M. V., Ram, A. et al.
Conditioned Place Preference Chamber
Cell
2023
A small molecule ligand for the novel pain target, GPR171, produces minimal reward in mice
Max V McDermott, Akila Ram et al.
Conditioned Place Preference Chamber
Pharmacology, biochemistry, and behavior
2023
Generation and characterization of a knock-in mouse model for Spastic Tetraplegia, Thin Corpus Callosum, and Progressive Microcephaly (SPATCCM), 24 April 2023, PREPRINT (Version 1) available at
Megan L. Ratz, Greg Leary et al.
Rotarod Test
Research Square
2023
Supraphysiologic doses of 17?-Estradiol aggravate depression-like behaviors in ovariectomized mice possibly via regulating microglial responses and brain glycerophospholipid metabolism, 08 May 2023, PREPRINT (Version 1) available at
Ming Li, Jing Zhang et al.
Open Field Test
Research square
2023
Concurrent behavioral and electrophysiological longitudinal recordings for in vivo assessment of aging
Christopher Daniel Morrone, Arielle A Tsang et al.
Barnes Maze
Frontiers in aging neuroscience
2023
The effect of selective nigrostriatal dopamine excess on behaviors linked to the cognitive and negative symptoms of schizophrenia
Moya, N. A., Yun, S. et al.
Automated T Maze
Neuropsychopharmacology
2023
Getting ahead of Alzheimer's disease: Early intervention with focused ultrasound
Noel, R. L., Gorman, S. L. et al.
Active Place Avoidance
Frontiers in Neuroscience
2023
Acetate supplementation rescues social deficits and alters transcriptional regulation in prefrontal cortex of Shank3 deficient mice
Aya Osman, Nicholas L Mervosh et al.
Elevated Zero Maze
Brain, behavior, and immunity
2023
Dorsomedial prefrontal hypoexcitability underlies lost empathy in frontotemporal dementia.
Hannah L Phillips, Huihui Dai et al.
Open Field Test
Neuron
2023
Peptidergic and functional delineation of the Edinger-Westphal nucleus
Michael F Priest, Sara N Freda et al.
Active/Passive Avoidance Shuttle Box
Cell reports
2023
Solriamfetol improves chronic sleep fragmentation-induced increases in sleep propensity and ameliorates explicit memory in male mice
Puech, C., Badran, M. et al.
Forced Swim Test
Sleep
2023
Generation and characterization of a knock-in mouse model for spastic tetraplegia, thin corpus callosum, and progressive microcephaly (SPATCCM)
Megan L Ratz-Mitchem, Greg Leary et al.
Rotarod Test
Mammalian genome : official journal of the International Mammalian Genome Society
2023
Early-life stress and ovarian hormones alter transcriptional regulation in the nucleus accumbens resulting in sex-specific responses to cocaine
Devin Rocks, Ivana Jaric et al.
Conditioned Place Preference Chamber
Cell reports
2023
Nature and nurture: Comparing mouse behavior in classic versus revised anxiety-like and social behavioral assays in genetically or environmentally defined groups
Janet Ronquillo, Michael T Nguyen et al.
Elevated Plus Maze
Genes, brain, and behavior
2023
An inhibitory circuit-based enhancer of DYRK1A function reverses Dyrk1a-associated impairment in social recognition
Yu-Tzu Shih, Jason Bondoc Alipio et al.
Open Field Test
Neuron
2023
Effects of in utero Exposure to CASPR2 Autoantibodies on Neurodevelopment and Autism Spectrum Disorder. School of Medicine at
Sex linked behavioral and hippocampal transcriptomic changes in mice with cell-type specific Egr1 loss
Swilley, C., Lin, Y. et al.
Tail Flick
Frontiers in Neuroscience
2023
Functional IgG Autoantibodies against Autonomic Nervous System Receptors in Symptomatic Women with Silicone Breast Implants
Talalai, E., Gorobets, D. et al.
Open Field Test
Cells
2023
SLC30A10 manganese transporter in the brain protects against deficits in motor function and dopaminergic neurotransmission under physiological conditions.
Cherish A Taylor, Stephanie M Grant et al.
Balance Beam
Metallomics
2023
PI3K block restores age-dependent neurovascular coupling defects associated with cerebral small vessel disease
Thakore P, Yamasaki E et al.
Y Maze
bioRxiv
2023
Liver-expressed antimicrobial peptide 2 elevation contributes to age-associated cognitive decline
Tian J, Guo L et al.
Fear Conditioning
JCI Insight
2023
Armstrong, Jessica L.? Preclinical Development of a Novel Serotonin Receptor Modulator for Fragile X Syndrome.?
Dopamine pathways mediating affective state transitions after sleep loss
Mingzheng Wu, Xin Zhang et al.
Active/Passive Avoidance Shuttle Box
Neuron
2023
Protocol for wireless deep brain stimulation in freely behaving mice with infrared light
Wu, X., Hong, G.
Y Maze
STAR Protocols
2023
Further Characterization of Multi-Organ DEARE and Protection by 16,16 Dimethyl Prostaglandin E2 in a Mouse Model of the Hematopoietic Acute Radiation Syndrome. Radiat Res. 2023 May 1;199(5):468-489. PMID: 37014943
Wu T, Pelus LM et al.
Y Maze
Radiation Research
2023
Microglial over-pruning of synapses during development in autism-associated SCN2A-deficient mice and human cerebral organoids. Research Square
Yang, Y., Wu, J. et al.
Y Maze
Research Square
2023
AJ76 and UH232 as potential agents for diagnosing early-stage Parkinson's disease. Neuropharmacology
Zhou, J., Li, J. et al.
Rotarod Test
Neuropharmacology
2023
AJ76 and UH232 as potential agents for diagnosing early-stage Parkinson's disease
Jingheng Zhou, Jicheng Li et al.
Rotarod Test
Neuropharmacology
2023
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Elevated Zero Maze
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Plos Biology
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PLoS Biol
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Generation and basic characterization of a gene-trap knockout mouse model of Scn2a with a substantial reduction of voltage-gated sodium channel Nav 1.2 expression. Genes Brain Behav 20(4):e12725
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Neuropathological and behavioral characterization of aged Grn R493X progranulin-deficient frontotemporal dementia knockin mice. Acta Neuropathol Commun
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American journal of cancer research
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Communications biology
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Molecular psychiatry
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Elevated Plus Maze
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Glia
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Estrogen Withdrawal Increases Postpartum Anxiety via Oxytocin Plasticity in the Paraventricular Hypothalamus and Dorsal Raphe Nucleus
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Open Field Test
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bioRxiv
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Social Behavior Is Modulated by Valence-Encoding mPFC-Amygdala Sub-circuitry
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Sociability Chamber
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Surgery, Anesthesia and Intensive Care Environment Induce Delirium-Like Behaviors and Impairment of Synaptic Function-Related Gene Expression in Aged Mice
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Dorsal hippocampus not always necessary in a radial arm maze delayed win-shift task
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PloS One
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Oxford Academic
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Nucleic acids research
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University of Toronto
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Regional differences in Alzheimer's disease pathology confound behavioural rescue after amyloid-? attenuation, Brain
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Oxford Academic
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Automated Radial Arm Maze
Scientific Reports
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Prenatal alcohol exposure reduces posterior dorsomedial striatum excitability and motivation in a sex- and age-dependent fashion
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Open Field Test
ScienceDirect
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Alterations of GABA B receptors in the APP/PS1 mouse model of Alzheimer's disease.
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Neurobiology of Aging
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Open Field Test
Physiological reports
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Ketamine restores escape behavior by re-engaging dopamine systems to drive cortical spinogenesis
Wu, M., Minkowicz, S. et al.
Active/Passive Avoidance Shuttle Box
bioRxiv
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TDP-43 mediated blood-brain barrier permeability and leukocyte infiltration promote neurodegeneration in a low-grade systemic inflammation mouse model
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Rotarod Test
Journal of Neuroinflammation
2020
Tip60 protects against amyloid-β-induced transcriptomic alterations via different modes of action in early versus late stages of neurodegeneration
Haolin Zhang, Haolin Zhang et al.
T - Maze
Molecular and cellular neurosciences
2020
Transcriptome analysis uncovers distinct modes of epigenetic gene changes in early versus late stages of amyloid-? induced Alzheimer's disease pathology
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T - Maze
Biorxiv
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Four Arms Plus Maze
International Journal of Comparative Psychology
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Differential expression of nicotine withdrawal as a function of developmental age in the rat
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Pharmacology, biochemistry, and behavior
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Autophagy protein NRBF2 has reduced expression in Alzheimer's brains and modulates memory and amyloid-beta homeostasis in mice. Mol Neurodegeneration
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Molecular Neurodegeneration
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Autophagy protein NRBF2 has reduced expression in Alzheimer's brains and modulates memory and amyloid-beta homeostasis in mice
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ProQuest
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Genetic background modifies CNS-mediated sensorimotor decline in the AD-BXD mouse model of genetic diversity in Alzheimer's disease
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Genes, brain, and behavior
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Effects of the second-generation "bath salt" cathinone alpha-pyrrolidinopropiophenone (?-PPP) on behavior and monoamine neurochemistry in male mice. Psychopharmacology 236, 1107'1117
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Springer
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Geer. K. M. Aberrant hippocampal neurogenesis contributes to learning and memory deficits in a mouse model of repetitive mild traumatic brain injury
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Virginia Tech
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Ultra-Fast Sensors to Study the Fundamental Neurochemistry Underlying Disease. University of South Carolina
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Elevated Zero Maze
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Dissociable Structural and Functional Hippocampal Outputs via Distinct Subiculum Cell Classes
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Cell
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Behavioral Phenotyping of an Improved Mouse Model of Phelan-McDermid Syndrome with a Complete Deletion of the Shank3 Gene
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eNeuro
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The Behavioral Effects of Oral Psychostimulant Ingestion on a Laboratory Rat Sample: An Undergraduate Research Experience. Journal of
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Nature
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S., An Evaluation of Alzheimer's Disease-related Pathology in Two Different Models of Diabetes in Immune-challenged Mice. University of Navada, Las Vegas Theses, Dissertations, Professional Papers, and Capstones. 3370
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Psychopharmacology
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The Role of Pre-Synaptic MUNC 13-1 in Voluntary Ethanol Consumption and Tolerance
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University of Houston Libraries
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Regulatory BC1 RNA in cognitive control
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Rhythmic brain stimulation reduces anxiety-related behavior in a mouse model based on meditation training
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Proceedings of the National Academy of Sciences of the United States of America
2017
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