Papers by Daniele Panetta
SAGE Open Medicine
Objectives: To investigate microstructural alterations of explanted long-term central venous cath... more Objectives: To investigate microstructural alterations of explanted long-term central venous catheters of totally implantable venous access devices, using micro-computed tomography. Methods: A total of 16 catheters (9 made of silicone and 7 made of polyurethane), all non-fractured, have been analyzed in this study. Eight catheters were implanted for an average duration of 994 days (min–max: 98–2731 days), while the remaining eight catheters (four for each material, forming the SIref and PUref control groups) were analyzed before implant and used as a reference. X-ray micro-computed tomography was used to reconstruct the three-dimensional geometry of selected segments of each catheter (ca. 10 cm per sample). Results: Morphometric analysis of the catheters revealed increases wall thickness and section area in the polyurethane group as compared with the reference central venous catheters of the same materials (wall thickness: 403 ± 12 μm in the polyurethane (PU) group vs 382 ± 4 μm in ...
Journal of Clinical Medicine
Photon-counting detector (PCD) is a novel computed tomography detector technology (photon-countin... more Photon-counting detector (PCD) is a novel computed tomography detector technology (photon-counting computed tomography—PCCT) that presents many advantages in the neurovascular field, such as increased spatial resolution, reduced radiation exposure, and optimization of the use of contrast agents and material decomposition. In this overview of the existing literature on PCCT, we describe the physical principles, the advantages and the disadvantages of conventional energy integrating detectors and PCDs, and finally, we discuss the applications of the PCD, focusing specifically on its implementation in the neurovascular field.
Journal of Visualized Experiments
Magnetic Resonance Imaging
American Journal of Physical Anthropology, Mar 1, 2019
This year's Presidential Panel (Saturday, 1-2:30pm) focuses on scientific and public discourse in... more This year's Presidential Panel (Saturday, 1-2:30pm) focuses on scientific and public discourse involving genetics and race: a topical issue that biological anthropologists are uniquely positioned to evaluate, discuss, and contribute. It follows the AAPA-AAAG-AAA-HBA sponsored symposium, Interpreting and Communicating Genetic Variation in 2019: A Conversation on Race. The Presidential Panel is an open session that will offer guided discussion and the opportunity to exchange ideas on the important issues raised in the symposium. Everyone is encouraged to attend and participate. Saturday brings our meetings to a close, with the Student Awards Ceremony and Closing Reception from 6:00-9:00 pm. Please join us to learn who won the 2019 Student Presentation Awards! Finally, as we approach the meetings, we will be publicizing additional information regarding special events. These will be listed in the final meetings program. My sincere thanks to everyone who helped assemble the 2019 program. Thanks are due to our extraordinary business partners, Lori Strong and her team (from Burk & Associates), as well as Ed Hagen (our webmaster, app developer, and member of the Cleveland Advance Team). We are immensely grateful to the 50 remarkable and dedicated members of our Program Committee, who conducted and completed reviews thoughtfully, thoroughly, and expeditiously. We also thank the Cleveland Advance Team. The team includes our colleagues and representatives from Burk who came together in Cleveland in January to arrange the scientific program and to finalize hotel details. The program assistant, Kathleen McGuire, has been a tremendous help, as have the Officers and other members of the Executive Committee. Special thanks to Leslie Aiello for stepping in on numerous occasions to help with details and evaluate workshop proposals. Finally, we extend our most sincere thanks to the Local Arrangements Committee, Dr. Denise Su and Yohannes Haile-Selassie. These meetings would not have been possible without all these exemplary individuals, so please join me in thanking them when you see them in Cleveland!
Journal of Archaeological Method and Theory
Personal ornaments are widely viewed as indicators of social identity and personhood. Ornaments a... more Personal ornaments are widely viewed as indicators of social identity and personhood. Ornaments are ubiquitous from the Late Pleistocene to the Holocene, but they are most often found as isolated objects within archaeological assemblages without direct evidence on how they were displayed. This article presents a detailed record of the ornaments found in direct association with an Early Mesolithic buried female infant discovered in 2017 at the site of Arma Veirana (Liguria, Italy). It uses microscopic, 3D, and positional analyses of the ornaments as well as a preliminary perforation experiment to document how they were perforated, used, and what led to their deposit as part of the infant’s grave goods. This study provides important information on the use of beads in the Early Mesolithic, in general, as well as the relationship between beads and young subadults, in particular. The results of the study suggest that the beads were worn by members of the infant’s community for a consider...
American Journal of Biological Anthropology
ObjectivesDuring the middle‐to‐upper Paleolithic transition (50,000 and 40,000 years ago), intera... more ObjectivesDuring the middle‐to‐upper Paleolithic transition (50,000 and 40,000 years ago), interaction between Neanderthals and Homo sapiens varied across Europe. In southern Italy, the association between Homo sapiens fossils and non‐Mousterian material culture, as well as the mode and tempo of Neanderthal demise, are still vividly debated. In this research, we focus on the study of two human teeth by using 3D geometric morphometric approaches for a reliable taxonomical attribution as well as obtaining new radiometric dates on the archeological sequence.Material and MethodsThis work presents two lower deciduous molars uncovered at Roccia San Sebastiano (Mondragone‐Caserta, Italy), stratigraphically associated with Mousterian (RSS1) and Uluzzian (RSS2) artifacts. To obtain a probabilistic attribution of the two RSS teeth to each reference taxa group composed of Neanderthals and Homo sapiens, we performed and compared the performance of three supervised learning algorithms (flexible ...
3D Image Reconstruction for CT and PET, 2020
Located in the southern Caucasus, Georgia was a major geographic corridor for hominin dispersal i... more Located in the southern Caucasus, Georgia was a major geographic corridor for hominin dispersal into Eurasia since the Early Pleistocene. During the Late Pleistocene it has been suggested that the region was inhabited by Neandertals until 37 ka cal BP [1], potentially replaced by modern humans 38-34 ka cal BP [2]. However, the scanty fossil human remains retrieved from Late Pleistocene deposits in Georgia did not provide to date sufficient information to identify the makers of specific technocomplexes. Here we use non-invasive digital methods to provide the first dental morphological description and morphometric analyses of Upper Paleolithic human remains from Dzudzuana and Satsurblia caves, in western Georgia. The Upper Palaeolithic sequence at Dzudzuana cave comprises three occupational episodes separated by millennia long hiatuses: the lowermost UP phase, Unit D, dated to 34.5–32.2 ka cal. BP; the following Unit C, dated to 27–24 ka cal. BP (the human teeth studied were retrieved from the lower part of this Unit); and the latest UP phase, Unit B dated to 16.5–13.2 ka cal. BP [3]. Human occupational layers at Satsurblia Cave yielded a series of living surfaces dated to (a) prior to the Last Glacial Maximum (LGM) at 25.5–24.4 ka cal. BP and (b) after the LGM at 17.9–16.2 ka cal. BP. Human remains were from Area B, from layers dated to the post-LGM phases dated to 13 ka cal BP [4]. Dzu 1 (Rdm2, Layer C3) and Dzu 2 (Rdm2, Layer C4) from Dzudzuana, SATP5-2 (Rdi1, Area B) and a left fragment of a juvenile mandible (bearing an erupted Ldm 2 , ID= SATP5-3, and LM 1 , and un-erupted LP 3 , LP 4 , and LM 2 , Area B) from Satsurblia were scanned using micro-CT system. The resulting image data were segmented in order to produce three-dimensional digital copies, which were used for both morphological description and morphometric analyses. Besides mesio-distal (MD) and bucco-lingual (BL) crown diameters, we used crown (for Dzu 1 and SATP5-3) and cervical (for SATP5-3) outline analyses and we assessed the 3D enamel thickness of the permanent teeth. The morphometric data were compared with a sample of Neandertals, Early H. sapiens, UP H. sapiens and recent /textitH. sapiens teeth available from the literature, except for MD and BL diameters of the permanent teeth as well as the 3D enamel thickness, for which an ex novo comparative dataset was created. All morphological features (e.g., cusp numbers, fissure pattern) observed in all teeth align with modern humans. BL crown diameters of Dzu 1 and Dzu 2 are small and fall closer to the modern human variability, as also confirmed by the crown outline analysis of Dzu 1. Similar morphometric results were obtained for the human remains from Satsurblia Cave. Crown diameters for deciduous and permanent teeth are closer to the modern human range of variation. Also the crown and cervical outlines of SATP5-3 fall within the modern human range of variability. Finally, all permanent teeth of the Satsurblia mandibular fragment show thick enamel, higher than the mean values computed for Neandertals but within modern human variability. Overall, our results support the attribution of the Upper Paleolithic technocomplexes of both Dzudzuana and Satsurblia caves to modern humans. Moreover, the human remains from Dzudzuana represent, up to now, the oldest evidence of modern humans from southern Caucasus.
European Journal of Nuclear Medicine and Molecular Imaging, 2014
European Journal of Nuclear Medicine and Molecular Imaging, 2016
3D Image Reconstruction for CT and PET, 2020
Product or corporate names may be trademarks or registered trademarks, and are used only for iden... more Product or corporate names may be trademarks or registered trademarks, and are used only for identification and explanation without intent to infringe.
Academic Radiology, 2020
Computed Tomography (CT) has long been regarded as a purely anatomical imaging modality. Recent a... more Computed Tomography (CT) has long been regarded as a purely anatomical imaging modality. Recent advances on CT technology and Contrast Agents (CA) in both clinical and preclinical cardiac imaging offer opportunities for the use of CT in functional imaging. Combined with modern ECG-gating techniques, functional CT has now become a reality allowing a comprehensive evaluation of myocardial global and regional function, perfusion and coronary angiography. This article aims at reviewing the current status of cardiac CT perfusion and micro-CT perfusion with established and experimental scanners and contrast agents, from clinical practice to the experimental domain of investigations based on animal models of heart diseases.
Uploads
Papers by Daniele Panetta