Action of snake venom Hemolytic snake venoms-such as those found in rattlesnakes, moccasins, and ... more Action of snake venom Hemolytic snake venoms-such as those found in rattlesnakes, moccasins, and lanceheads-are complex cocktails of proteases, phospholipases, and phosphodiesterases. One protein found in the venom of lancehead vipers (genus Bothrops) is botrocetin, which causes aggregation of blood platelets wherever von Willebrand Factor (vWF) is present in the bloodstream (1). By binding vWF, botrocetin promotes inappropriate systemic clotting, reducing the ability of vWF to respond to ruptures caused by proteolytic venom proteins and promoting hemorrhage.
Shrew mice of the genus Archboldomys are poorly known members of an endemic clade of vermivorous/... more Shrew mice of the genus Archboldomys are poorly known members of an endemic clade of vermivorous/insectivorous murid rodents confined to Luzon Island, Philippines. Three species of these small, ground-living, diurnal mice were previously known, all from a handful of specimens from a few localities. The pattern of morphological and genetic differentiation among additional specimens of shrew mice from our recent field surveys in the Central Cordillera and Sierra Madre mountains of Luzon document the presence of two distinct species groups within Archboldomys as previously defined, as well as three new species. Gene-sequence data from the mitochondrial cytochrome b and nuclear IRBP genes confirm the existence of six distinct species, but also show that Archboldomys, as previously defined, is composed of two clades that are not sister taxa. Reevaluation of the presumed morphological synapomorphies among these shrew mice, together with analyses of karyological and gene-sequence data, support the following: (1) erection of Soricomys, new genus;
Shrew mice of the genus Archboldomys are poorly known members of an endemic clade ofvermivorous/i... more Shrew mice of the genus Archboldomys are poorly known members of an endemic clade ofvermivorous/insectivorous murid rodents confined to Luzon Island, Philippines. Three species of
these small, ground-living, diurnal mice were previously known, all from a handful of specimens from a few localities. The pattern of morphological and genetic differentiation among additional
specimens of shrew mice from our recent field surveys in the Central Cordillera and Sierra Madre mountains of Luzon document the presence of two distinct species groups within Archboldomys as previously defined, as well as three new species. Gene-sequence data from the mitochondrial cytochrome b and nuclear IRBP genes confirm the existence of six distinct species, but also show that Archboldomys, as previously defined, is composed of two clades that are not sister taxa. Reevaluation of the presumed morphological synapomorphies among these shrew mice, together with analyses
of karyological and gene-sequence data, support the following: (1) erection of Soricomys, new genus;
(2) transfer of A. kalinga and A. musseri to Soricomys; and
(3) recognition of Archboldomys maximus, n. sp., Soricomys leonardocoi, n. sp., and Soricomys montanus, n. sp.
The new genus and species are described, and their phylogenetic relationships, biogeography, and conservation are discussed.
Action of snake venom Hemolytic snake venoms-such as those found in rattlesnakes, moccasins, and ... more Action of snake venom Hemolytic snake venoms-such as those found in rattlesnakes, moccasins, and lanceheads-are complex cocktails of proteases, phospholipases, and phosphodiesterases. One protein found in the venom of lancehead vipers (genus Bothrops) is botrocetin, which causes aggregation of blood platelets wherever von Willebrand Factor (vWF) is present in the bloodstream (1). By binding vWF, botrocetin promotes inappropriate systemic clotting, reducing the ability of vWF to respond to ruptures caused by proteolytic venom proteins and promoting hemorrhage.
Shrew mice of the genus Archboldomys are poorly known members of an endemic clade of vermivorous/... more Shrew mice of the genus Archboldomys are poorly known members of an endemic clade of vermivorous/insectivorous murid rodents confined to Luzon Island, Philippines. Three species of these small, ground-living, diurnal mice were previously known, all from a handful of specimens from a few localities. The pattern of morphological and genetic differentiation among additional specimens of shrew mice from our recent field surveys in the Central Cordillera and Sierra Madre mountains of Luzon document the presence of two distinct species groups within Archboldomys as previously defined, as well as three new species. Gene-sequence data from the mitochondrial cytochrome b and nuclear IRBP genes confirm the existence of six distinct species, but also show that Archboldomys, as previously defined, is composed of two clades that are not sister taxa. Reevaluation of the presumed morphological synapomorphies among these shrew mice, together with analyses of karyological and gene-sequence data, support the following: (1) erection of Soricomys, new genus;
Shrew mice of the genus Archboldomys are poorly known members of an endemic clade ofvermivorous/i... more Shrew mice of the genus Archboldomys are poorly known members of an endemic clade ofvermivorous/insectivorous murid rodents confined to Luzon Island, Philippines. Three species of
these small, ground-living, diurnal mice were previously known, all from a handful of specimens from a few localities. The pattern of morphological and genetic differentiation among additional
specimens of shrew mice from our recent field surveys in the Central Cordillera and Sierra Madre mountains of Luzon document the presence of two distinct species groups within Archboldomys as previously defined, as well as three new species. Gene-sequence data from the mitochondrial cytochrome b and nuclear IRBP genes confirm the existence of six distinct species, but also show that Archboldomys, as previously defined, is composed of two clades that are not sister taxa. Reevaluation of the presumed morphological synapomorphies among these shrew mice, together with analyses
of karyological and gene-sequence data, support the following: (1) erection of Soricomys, new genus;
(2) transfer of A. kalinga and A. musseri to Soricomys; and
(3) recognition of Archboldomys maximus, n. sp., Soricomys leonardocoi, n. sp., and Soricomys montanus, n. sp.
The new genus and species are described, and their phylogenetic relationships, biogeography, and conservation are discussed.
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Papers by Tim Sosa
these small, ground-living, diurnal mice were previously known, all from a handful of specimens from a few localities. The pattern of morphological and genetic differentiation among additional
specimens of shrew mice from our recent field surveys in the Central Cordillera and Sierra Madre mountains of Luzon document the presence of two distinct species groups within Archboldomys as previously defined, as well as three new species. Gene-sequence data from the mitochondrial cytochrome b and nuclear IRBP genes confirm the existence of six distinct species, but also show that Archboldomys, as previously defined, is composed of two clades that are not sister taxa. Reevaluation of the presumed morphological synapomorphies among these shrew mice, together with analyses
of karyological and gene-sequence data, support the following: (1) erection of Soricomys, new genus;
(2) transfer of A. kalinga and A. musseri to Soricomys; and
(3) recognition of Archboldomys maximus, n. sp., Soricomys leonardocoi, n. sp., and Soricomys montanus, n. sp.
The new genus and species are described, and their phylogenetic relationships, biogeography, and conservation are discussed.
these small, ground-living, diurnal mice were previously known, all from a handful of specimens from a few localities. The pattern of morphological and genetic differentiation among additional
specimens of shrew mice from our recent field surveys in the Central Cordillera and Sierra Madre mountains of Luzon document the presence of two distinct species groups within Archboldomys as previously defined, as well as three new species. Gene-sequence data from the mitochondrial cytochrome b and nuclear IRBP genes confirm the existence of six distinct species, but also show that Archboldomys, as previously defined, is composed of two clades that are not sister taxa. Reevaluation of the presumed morphological synapomorphies among these shrew mice, together with analyses
of karyological and gene-sequence data, support the following: (1) erection of Soricomys, new genus;
(2) transfer of A. kalinga and A. musseri to Soricomys; and
(3) recognition of Archboldomys maximus, n. sp., Soricomys leonardocoi, n. sp., and Soricomys montanus, n. sp.
The new genus and species are described, and their phylogenetic relationships, biogeography, and conservation are discussed.