Papers by Funda Catan Inan
Türkiye klinikleri tıp bilimleri dergisi, Dec 31, 2022
Pnömoni, çoğunlukla bakteri ve virüsler gibi patojenik mikroorganizmaların neden olduğu akciğer p... more Pnömoni, çoğunlukla bakteri ve virüsler gibi patojenik mikroorganizmaların neden olduğu akciğer parankiminin inflamasyonudur. Özellikle 5 yaşından küçük çocukların immün fonksiyonları ve solunum sistemleri yeteri kadar olgunlaşmamış olduğundan tedavi edilmezlerse veya yanlış tedavi edilirlerse kalp yetersizliği, ensefalopati veya şok gibi ciddi durumlara yol açabilir ve bu nedenle daha ölümcül seyre-
Archives of clinical and biomedical research, 2022
Background: Most of the documented literature to date has reported that the COVID-19 pandemic is ... more Background: Most of the documented literature to date has reported that the COVID-19 pandemic is associated with greater distress, anxiety, anger, stress, and agitation among the general public compared to before the onset of the pandemic. Method and study design: A review was done to now the evidence for the antiviral and immunemodulatory properties of micronutrients. A search was done in PubMed, Scopus, and Google Scholar for the nutrients with proven effect against viral infection.
International journal of technology in teaching and learning, 2022
One of the most emphasized skills for social, educational and workplace settings is creativity in... more One of the most emphasized skills for social, educational and workplace settings is creativity in the present decade. This study aims to understand whether a collaborative digital storytelling production project improves the creativity of undergraduate students. 109 students engaged in group work and employed a range of digital tools (i.e. wikis, storyboard creation tools, video editing programs) for creating digital stories about the 21stcentury problems they think relevant. Students were able to review and comment on each other’s scenarios and pres ent their digital stories to their classmates at the end of the project. The adapted version of ‘How Creative Are You?’ scale (Whetten & Cameron, 2011) was used for measuring the students’ creativity scores before and after the implementation. Whereas resu lts indicated that creativity scores were increased by the digital storytelling production project, this effect was not significant. However, observation of the production process revealed some components of creative thinking skills of students.
British journal of medicine and medical research, Jan 10, 2016
This work was carried out in collaboration between all authors. Author AB designed and supervised... more This work was carried out in collaboration between all authors. Author AB designed and supervised the study and involved in data collection, statistical analysis, the writing of the paper. Author AOAAAH involved in data collection, interpretation of data and writing manuscript. Authors FC, KUR and MG involved in interpretation of data and writing manuscript. All authors approved the final version.
PubMed, Oct 1, 2019
Background: The aim of the present study was to determine the prevalence of disordered internet u... more Background: The aim of the present study was to determine the prevalence of disordered internet use among adolescent university students and its association with various health complaints and behaviours, and most importantly to examine the psychometric properties of 9-item Internet Disorder Scale-Short Form (IDS9-SF) using factor analyses and Rasch analysis. Methods: A total of 1988 university students aged 18 to 25 years were selected via a multi-stage stratified random sampling technique among university students in Istanbul, Turkey (September 2017 to February 2018). Data collected included socio-demographics, lifestyle and dietary habits, and the 9-item IDS9-SF. Statistical analysis included descriptive statistics, multivariate analyses, factor analyses, path analysis, and Rasch analysis. Findings: Using confirmatory factor analysis (CFA), the study investigated the latent structure of the IDS9-SF instrument and results supported its reliability and validity. The prevalence of disordered internet use was 18.3% in the sample. There were significant differences between those who had disordered internet use and those who did not in gender, family income, school performance, number of bedrooms at home, and number of people living at home, as well as internet use duration. Using multivariate regression analysis, key predictors of disordered internet use included (among others): gender, body mass index (BMI), household income, number of people living at home, having a computer at home, internet facilities, duration of internet use, sleeping hours, frequency of eating fast food, watching television, headache, hurting eyes, tired eyes, and hearing problems. Rash analysis demonstrated that four of the nine items (2, 3, 6, and 7) were more difficult for individuals to endorse compared to other items. Conclusion: Problems arising from excessive internet use were apparent among the study sample and the IDS9-SF is a valid and reliable measure for assessing disordered internet use among Turkish adolescent population.
Children (Basel), Mar 9, 2023
This article is an open access article distributed under the terms and conditions of the Creative... more This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY
The aim of the present study was to determine the prevalence of disordered internet use among ado... more The aim of the present study was to determine the prevalence of disordered internet use among adolescent university students, its association with various health complaints, and behaviors, and most importantly to examine the psychometric properties of IDS9-SF. Despite the many potential benefits associated with using the internet, numerous problems such as exposure to inappropriate images and content, absence of privacy, and internet addiction (IA) among a small minority have been reported as a result of this increasing usage [1]. Although internet addiction has been identified as a prevalent problem among a small minority of the population, it has never been classed as a formal disorder most likely because internet addiction is an umbrella term covering more specific online problematic behaviors such as online problematic gaming and problematic social media use [2]. Many psychometric studies have been carried out and there are over 20 different assessment scales that have been developed to assess problematic internet use behavior [3]. Irrespective of whether disordered internet use is an addiction, research has consistently shown that eexcessive internet use can lead to psychological and behavioral problems among a small minority of individuals [4], including physical health issues (e.g., dry eyes, neck, back and shoulder pain, regular headaches, numbness pain in the thumb, index and middle fingers) [5, 6]. Furthermore, there have been many reporting negative of impacts of excessive internet use among adolescents including poor dietary habits [7], physical inactivity, lack of adequate sleep [5, 8] increased depression and loneliness, and social anxiety [5, 9]. Table 1. Socio-demographic characteristics of participants (N=1,988) with and without internet disorder
Erciyes medical journal, 2020
The aim of this study was to determine the relationship between microvascular Type 2 diabetes mel... more The aim of this study was to determine the relationship between microvascular Type 2 diabetes mellitus (T2DM) complications and the severity and duration of diabetes in the light of sociodemographic and lifestyle variables. Materials and Methods: This is a prospective cohort study based on 899 (527 females, 372 males) patients with T2DM aged 25-70 years. Patient information including socio-demographic variables; body mass index (BMI); lifestyle habits and duration of diabetes; treatment of diabetes; values for hemoglobin A1c (HbA1c); development of diabetes complications; and the presence of neuropathy, nephropathy, and retinopathy were recorded. A univariate and multivariate statistical analysis were performed. Results: Significant differences were found between diabetics with HbA1c ≤7 and >7 in terms of the education level, occupation, household income, duration of diabetes, the number of children, smoking, physical exercise, eating fast food, control regularity, and diabetes education. A total of 17.1% of patients had diabetic retinopathy, 17.0% had neuropathy, and 13.7% had nephropathy. Among diabetics, 2.3% had three microvascular complications, whereas 66.6% had none of them. The prevalence of diabetes complications was lower in patients who had good glycemic control than those who had poor glycemic control. Furthermore, the highest reduction in the level of HbA1c was for sulfonylurea usage. Conclusion: A high prevalence of diabetes complications is a burden for both the patients and the health care system. Screening, early diagnosis, management of the glucose level, and the follow-up may result in delayed diabetes complications.
JCPSP. Journal of the College of Physicians & Surgeons Pakistan, May 1, 2022
Objective: To determine the relationship between lipid profile and non-alcoholic fatty liver dise... more Objective: To determine the relationship between lipid profile and non-alcoholic fatty liver disease in obese children and adolescents. Study Design: A comparative cross-sectional study.
Annals of African Medicine, 2018
Background: Fasting during the holy month of Ramadan is a religious obligation for all Muslims wh... more Background: Fasting during the holy month of Ramadan is a religious obligation for all Muslims who represent 1.8 billion of the world population (24%). This study explores the effect of Ramadan fasting on the blood glucose, glycated hemoglobin (HbA1c), lipid profile, sleeping quality, and essential lifestyle parameters and also explores the safety of fasting for a whole month among diabetic patients. Aim: The aim of the present study was to assess the impact of Ramadan fasting on the blood glucose, HbA1c, lipid profile, sleeping quality, and lifestyle parameters among patients with type 2 diabetes mellitus (T2DM) in Turkey. Subjects and Methods: A total of 1780 diabetic patients were approached, and 1246 (70%) participated in this cross-sectional study carried out during the period from May 27, 2017, to June 24, 2017. Data analysis comprised sociodemographic features, lifestyle habits, blood pressure measurements, serum lipid profiles, serum calcium, Vitamin D 25-hydroxy, uric acid, and HbA1c at before 4 weeks and after 12 weeks from Ramadan. Results: Out of 1246 patients, 593 (47.6%) were male and 653 (52.4%) were female. The mean ± standard deviation age of the patients was 50.39 ± 15.3 years. Males were significantly older than females (51.53 ± 12.56 vs. 49.26 ± 14.4; P = 0.003, respectively). Significant differences were found in Vitamin D, blood glucose, HbA1c level, creatinine, bilirubin, albumin, total cholesterol, triglycerides, high-density lipoprotein-cholesterol (female), low-density lipoprotein-cholesterol (male), uric acid, and systolic and diastolic blood pressure after and before the holy month of Ramadan (P < 0.05 for each). HbA1c (P < 0.001), physical activity (P < 0.001), hours of sleeping (P < 0.001), systolic blood pressure (BP) (mmHg) (P = 0.007), BMI (P = 0.016), diastolic BP (mmHg) (P = 0.018), family history (P = 0.021), and smoking (P = 0.045) were identified as significantly associated with Ramadan fasting as contributing factors. Conclusion: In one of the largest studies of its kind, we show that Ramadan fasting has positive effects on T2DM patients as it reduces their blood pressure, blood glucose, HbA1C, and BMI. Furthermore, there are improvements in the duration of sleep and physical activity, the role of Ramadan fasting in diabetes therapy has been confirmed.
The brain is a complex system which contains a large number of neurons. This complex nature of th... more The brain is a complex system which contains a large number of neurons. This complex nature of the brain can be simplified by mathematical models. Mathematical models are almost equally as important as biological experiments and represent some part of the real world by mathematical terms. They help us to understand mathematical neuroscience. The functional dynamics of brain and the behaviour of neurons have become popular recently. Hence, mathematical neuroscience becomes an attractive prospective to study because of a large availability of biological and computation data. In the first part of the thesis, we outline a literature review covering background material for this thesis. Neuroimaging techniques are used to understand the structure and dynamics of the brain. Then, we analyse the Liley and Janset-Rit model as the neural mass models. After a brief and selective description of neurobiology, our study demonstrates the relationship between functional connectivity (FC) and structural connectivity (SC) via using Wilson-Cowan model. The bifurcation diagram of Wilson-Cowan model is plotted in XPP package programme. While SC is calculated from CoComac database which are taken from the macaque brain, FC is calculated by correlation. Then, the relationship between FC and SC is measured by the Pearson and Spearman correlation. A greater similarity is seen along the border of the Hopf bifurcation. Hence, phase response curves are calculated by the adjoint method, and then phase interaction functions are produced in Matlab in order to examine the stability of the synchronised solutions. Following this, one question of interest is the relationship between epileptic discharges as measured by EEG and the haemodynamic response as measured by fMRI. The haemodynamic model is discussed and its outputs as BOLD signals are computed. Then, the haemodynamic model is coupled to the Wilson-Cowan model and the Liley model. Eventually the BOLD signals are calculated after coupling. The system has BOLD signal dynamics including an initial dip, positive response and poststimulus undershoot.
Aging medicine and healthcare, Jun 30, 2023
Journal of Infection in Developing Countries, Jan 31, 2023
Journal of hearing science, Sep 30, 2022
Background: Hearing loss and hypertension are leading causes of disability, affecting over 360 mi... more Background: Hearing loss and hypertension are leading causes of disability, affecting over 360 million people. The aim of this study was to assess the impacts of factors such as vitamin D and sleep disorder on the risk of hearing loss among hypertensive patients. Material and methods: This prospective cohort study involved 885 patients aged between 25 and 65 years old who visited our ENT and Endocrinology departments. The study was based on biochemical tests, physical examination, hearing assessment, and Pittsburgh Sleep Quality Index test. Statistical analysis used bivariate and multivariate stepwise regression. Results: Of 855 hypertensive patients, 184 (21.5%) had hearing loss. There were statistically significant differences between hypertensive patients with and without hearing loss in terms of BMI, smoking, family history of diabetes, tinnitus, vertigo, and headache. Moreover, there were statistically significant differences between hypertensive patients with hearing loss versus those with normal hearing in terms of vitamin D, calcium, magnesium, potassium, fasting glucose, HbA1C, HDL, systolic and diastolic blood pressure, microalbuminuria, and sleep quality. Among hypertensive patients, a multivariate regression analysis (stepwise method) indicated that vertigo, systolic blood pressure, vitamin D deficiency, numbness in the hand, tinnitus, vigorous activity, metabolic syndrome, sleep disturbance, and obesity were all risk predictors of hearing loss. Conclusions: Controlling hypertension, vitamin D level, sleep, and lifestyle might lower the risk of hearing loss among hypertensive patients.
Turkish journal of family medicine and primary care, Sep 10, 2021
Aim: Acute gastroenteritis (AGE) is one of the important causes of mortality and morbidity for ch... more Aim: Acute gastroenteritis (AGE) is one of the important causes of mortality and morbidity for children worldwide, especially in developing countries. Rotavirus is transmitted by the feces of the people carrying it through food and hands. Additionally, door handles, telephones, sockets, and toys may play a role in spreading the infection. In addition to fecal-oral transmission, transmission via droplets has also been reported. In this study, we aimed to evaluate the frequency and characteristics of rotavirus in pediatric acute gastroenteritis cases in our institution and reveal the effect of the increased mask, social distancing and general hygiene recommendations with COVID-19 pandemic on rotavirus gastroenteritis. Methods: A total of 4781 patients aged 0-18 diagnosed with AGE between January 2019 and December 2020 were included in the study. The rotavirus positivity of patients diagnosed with acute gastroenteritis before and after the pandemic was statistically compared according to season, gender, and age variables. Results: Four hundred nine (8.6%) of 4781 patients were determined as rotavirus positive. The frequency of rotavirus in the age range of 0-2 was higher than that of in the other age ranges. Rotavirus is more common in the winter and spring seasons. In the modeling performed for patients with AGE in our hospital, provided that the other variables remained constant, the risk of rotavirus positivity increased by 1.14 times with the season variable while it decreased by 0.66 times with age. It was concluded that as the age increased, the odds value of being rotavirus positive decreased by 33.4%. While the prevalence of rotavirus gastroenteritis was 7.5% between March 2019 and December 2019, this frequency decreased to 4.7% with the pandemic (March 2020-December 2020), which was statistically significant (X 2 =8.620; p=0.003). Conclusion: Increasing masks, social distancing and general hygiene recommendations due to COVID 19 have led to a decrease in the frequency of rotavirus infections in children.
The Nigerian journal of general practice, 2016
Aim: The aim of the present study is to determine the frequency of mobile phone use while driving... more Aim: The aim of the present study is to determine the frequency of mobile phone use while driving and associated factors in a sample of road traffic among Turkish drivers in Istanbul. Design: This is a cross-sectional study design. Subjects and Methods: The study included a representative sample of 1200 drivers. However, 891 drivers agreed to participate and completed the driver behavior questionnaire (DBQ). Methods: The Manchester DBQ was used to measure the aggressive and aberrant driving behaviors causing accidents in terms of sociodemographics, driving attitudes, and behaviors, adherence to traffic laws, and mobile phone use. Results: The present study expressed that the frequency of mobile phone use while driving was very high among Turkish drivers who were involved with traffic crashes. There was a significant difference found between mobile phone users and nonusers while driving in age group (P < 0.01), education (P < 0.001), occupation (P < 0.001), seat belt use (P < 0.001), vehicle type (P < 0.001), and excessive speed (P < 0.001). Furthermore, attempting to overtake, missing give way signal, and turning right/left nearly hitting other car were reported as errors. For lapses, there was no significant association found between correct and incorrect parking for drivers in all of the DBQ items. The data showed that the drivers reported higher mean scores of violations such as driving close to the car to go faster, running a red light, disregarding speed limit at night or early in the morning. Conclusion: Together, the results provide important insights into mobile phone use and its related factors among Turkish drivers. The type of vehicle, excessive speeding, occupational status, educational level, age group, seat belt use, and crossing a red light were statistically significant associated with mobile phone use among drivers who were involved in the road crashes. When drivers use a mobile phone, there is an increased likelihood of the road accidents that result in injury. There is no doubt that hands-free phone use while driving may not minimize the risk totally. In fact, advancing technology will increase mobile phone use in motor vehicles so it may cause more crashes and fatalities.
Aging Medicine and Healthcare
Children (Basel), Mar 9, 2023
This article is an open access article distributed under the terms and conditions of the Creative... more This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY
The Journal of Infection in Developing Countries
Introduction: Despite significant advances in the management of patients with COVID-19, there is ... more Introduction: Despite significant advances in the management of patients with COVID-19, there is a need for markers to guide treatment and predict disease severity. In this study, we aimed to evaluate the relationship of the ferritin/albumin (FAR) ratio with disease mortality. Methodology: Acute Physiology and Chronic Health Assessment II scores and laboratory results of patients diagnosed with severe COVID-19 pneumonia were retrospectively analyzed. The patients were divided into two groups: survivors and non-survivors. Data for ferritin, albumin, and ferritin/albumin ratio among COVID-19 patients were analyzed and compared. Results: The mean age was higher in non-survivors (p = 0.778, p < 0.001, respectively). The ferritin/albumin ratio was significantly higher in the non-survival group (p < 0.05). Taking the cut-off value of the ferritin/albumin ratio of 128.71 in the ROC analysis, it predicted the critical clinical status of COVID-19 with 88.4% sensitivity and 88.4% specif...
Archives of clinical and biomedical research, 2022
Background: Most of the documented literature to date has reported that the COVID-19 pandemic is ... more Background: Most of the documented literature to date has reported that the COVID-19 pandemic is associated with greater distress, anxiety, anger, stress, and agitation among the general public compared to before the onset of the pandemic. Method and study design: A review was done to now the evidence for the antiviral and immunemodulatory properties of micronutrients. A search was done in PubMed, Scopus, and Google Scholar for the nutrients with proven effect against viral infection.
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Papers by Funda Catan Inan