How to Analyze Proteomics Data
How to Analyze Proteomics Data Using Omics Playground Steps involved in the analysis, statistical methods applied and suggested analyses to visually interpret your proteomics data. Published on December 23rd, 2024⏱ …
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Streamlined Proteomics and Transcriptomics Data Analysis for Drug Discovery in Oncology
Streamlined Proteomics and Transcriptomics Data Analysis for Drug Discovery in Oncology Analyze omics data and explore biomarkers and pathways with no coding expertise required. Download the case study Try Omics …
Key Challenges in Multi-omics Data Integration
Key Challenges in Multi-Omics Data Integration Published on October 21, 2025Written by Antonino Zito 10 min read Introduction Multi-omics data integration aims to harmonize multiple layers of biological data, such …
BigOmics Analytics Raises the First Tranche of its Next Round
BigOmics Analytics Successfully Completes the First Tranche of its Next Round to Fast-track Omics Data Analysis and Unlock Precision Medicine Lugano, October 8, 2025 – BigOmics Analytics, a Swiss bioinformatics …
Guide to Public RNA-Seq and single-cell RNA-Seq Databases: a Comparative Review
The Ultimate Guide to Public RNA-Seq and single-cell RNA-Seq Databases: a Comparative Review Last updated on September 2025 13 min read Introduction The wealth of publicly available RNA-sequencing (RNA-seq) and single-cell …
Introduction to WGCNA: Applications in Gene Correlation Network Analysis
A Complete Guide to WGCNA: Applications in Gene Correlation Network Analysis Published on October 2, 2025Last updated on February 23, 2026 by Antonino Zito 10 min read Introduction Weighted gene co-expression …
Using Omics Playground to Analyze Olink Proteomic Data
Using Omics Playground to Analyze Olink Proteomic Data Published on August 6th, 2025 3 min read Introduction Olink Target proteomics data are protein measurements obtained using Olink’s Proximity Extension Assay …
Efficient Single-Sample Gene Set Enrichment Scoring Methods for Large-Scale Datasets
Efficient Single-Sample Gene Set Enrichment Scoring Methods for Large-Scale Datasets Published on July 23, 2025Written by Antonino Zito⏱ 4 min read The prominent problem of scalable single sample gene set …
Combining Multi-Omics Factorization Methods for Robust Biomarker Identification
Combining Multi-Omics Factorization Methods for Robust Biomarker Identification Written by Ivo Kwee⏱ 5 min read Introduction Multi-omics biomarker identification is crucial for advancing biomedical research and personalized medicine. Computational genomic …
Preprocessing of MS-based Proteomics Data: Overview and Software Options
Preprocessing of MS-based Proteomics Data: Overview and Software Options Published on April 23nd, 2025Written by Shujia Dai, Ph.D⏱ 12 min read Introduction to Proteomics Data Preprocessing Mass spectrometry (MS)-based proteomics …
From Raw Data to Therapeutic Insights: End-to-End RNA-Seq Analysis of IL-17A in Osteoarthritis
USE CASE From Raw Data to Therapeutic Insights: End-to-End RNA-Seq Analysis of IL-17A in Osteoarthritis Written by Axel Martinelli in collaboration with Almaden Genomics. Introduction In 2021 Mimpen et al. …
How to Identify Biomarkers: Definition, Examples, and Algorithms for Detection
How to Identify Biomarkers:Definition, Examples, and Algorithms for Detection How to Identify Biomarkers: Definition, Examples, and Algorithms for Detection ⏱ 9 min readby Axel Martinelli Introduction Novel biomarker discovery is crucial …
Why and How to Normalize RNA-Seq Data
In this article, we give an overview of why RNA-seq normalization is essential, and we break down different RNA-seq normalization methods to help you master your next RNA-seq analysis.
A Short Guide to Enrichment Analysis
A Short Guide to Enrichment Analysis by Ivo Kwee, CTO Enrichment Analysis (EA), or also called Gene Set Analysis (GSA), is a computational method used to analyze gene expression data …
Synergizing mTOR Inhibitors with STL001’s Enhanced Modes of Action and Tetrandrine Potential
Advancing Cancer Therapeutics: Synergizing mTOR Inhibitors with STL001’s Enhanced Modes of Action and Tetrandrine Potential Written by Axel Martinelli in collaboration with Lexogen⏱ 6 min read FOXM1, a transcription factor …
Proteomics Normalization: Methods and How to Choose the Best One for Your Data
Proteomics Normalization: Methods and How to Choose the Best One for Your Data A guide to proteomics normalization and methods involved to get the most out of your analysis Published …
Insights into Aging from the GTEx Tissue Collection: Exploring Biomarkers of Aging and Aging Pathways
Insights into Aging from the GTEx Tissue Collection Exploring Biomarkers of Aging and Aging Pathways Written by Axel Martinelli⏱ 9 min read Last updated on December 6th, 2024Published on August …
How to Perform Differential Gene Expression Analysis
How to Perform Differential Gene Expression Analysis Steps in analyses of gene expression data and popular differential gene expression analysis methods Published on January 30th, 2024 by Antonino Zito, PhD ⏱ 6 …
What are Batch Effects and How to Correct Them
What are Batch Effects in Omics Data and How to Correct Them The Tricky Problem of ‘Batch Effects’ in Biological Data Published on March 8th, 2024Last updated on November 12th, …
What’s New in Omics Playground V3.5: A Complete Guide to the Latest Features
What’s New in Omics Playground V3.5: A Complete Guide to the Latest Features Published on November 12th, 2024⏱ 13 min read Introduction We are thrilled to announce the latest release of …
Top Pharmacogenomics Databases for Drug Discovery
Top Pharmacogenomics Databases for Drug Discovery Published on November 8th, 2024⏱ 4 min read Introduction Pharmacogenomics databases are indispensable resources for drug discovery and development. These databases compile extensive datasets on …
Reanalyzing Olink Proteomics Data with Omics Playground: Uncovering Therapeutic Drug Potential for Sarcoidosis
Reanalyzing Olink Proteomics Data with Omics Playground: Uncovering Therapeutic Drug Potential for Sarcoidosis Published on October 14th, 2024by Axel Martinelli ⏱ 5 min read Introduction Omics Playground supports a wide …
How to Prepare Your RNA-Seq and Proteomics Data for Omics Playground
How to Prepare your RNA-Seq and Proteomics data for Omics Playground Last updated on December 13th, 2024First Published on February 22nd, 2023⏱ 9 min read Omics Playground is a cloud-based …
How to Upload your RNA-Seq and Proteomics Data to Omics Playground
How to Upload Your RNA-Seq and Proteomics Data to Omics Playground Step-by-step tutorial Last Updated on December 10th, 2024Published on February 5th, 2024⏱ 13 min read Introduction In this step-by-step guide, …
Fast and Flexible Omics Data Analysis for Proteomics Research in Oncology
Fast and Flexible Omics Data Analysis for Proteomics Research in Oncology Download the case study Client Profile The Section for Translational Surgical Oncology and Biomaterial Banks at the University of …
Biomarker Data Analysis with Omics Playground: A Step-by-Step Tutorial
Biomarker Data Analysis with Omics Playground: A Step-by-Step Tutorial Published on June 3rd, 2024 Written by Axel Martinelli ⏱ 9 min read Introduction In this biomarker data analysis tutorial, we will guide …
Achieving End-to-End Omics Data Analysis and Facilitating Interactive Results Sharing in Sequencing Units
Achieving End-to-End Omics Data Analysis and Facilitating Interactive Results Sharing in Sequencing Units Published on March 28th, 2024by Murat Akhmedov ⏱ 12 min read Introduction I recently had the opportunity to …
Fast, Flexible and Creative Omics Data Analysis for Cancer Drug Discovery
Fast, Flexible and Creative Omics Data Analysis for Cancer Drug Discovery ✅ Rapid data retrieval and reanalysis. ✅ Efficient Biomarker Identification ✅ Simplified insight extraction Download the case study Request …
Beyond Basic Transcriptomics Data Analysis: How to Extract the Most Information from Your Data
Beyond Basic Transcriptomics Data Analysis: How to Extract the Most Information from Your Data 7 approaches for your transcriptomics data analysis to get the most out of your experiments. Published …
BigOmics and Almaden Genomics Collaborate to Provide End-to-End Omics Data Analysis
BigOmics and Almaden Genomics Collaborate to Provide End-to-End Omics Data Analysis Published on February 22nd, 2024⏱ 3 min read LUGANO, Switzerland – February 22nd, 2024 – BigOmics Analytics has announced its …
Unleashing the Power of httpOnly Cookies in R Shiny Applications: A Comprehensive Guide
Unleashing the Power of httpOnly Cookies in R Shiny Applications A Comprehensive Guide Published on February 20th, 2024Written by Xavier Escribà Montagut, Software engineer ⏱ 13 min read What’s In Store? …
Three Shades of Bioinformatics: Full service, Self-Service, Governed Self-Service Analytics
Three Shades of Bioinformatics Analysis: Full Service, Self-Service, Governed Self-Service Analytics The Role of Omics Data Analysis Solutions in Bioinformatics Analysis Published on February 6th, 2024 by Murat Akhmedov, CEO ⏱ 9 …
Omics Data Analysis Software as an Educational and Training Tool
Omics Data Analysis Software as an Educational and Training Tool Omics Playground: Your Essential Solution for Data Analysis Training and Publication Reviewing Published on January 16th, 2024⏱ 5 min read Introduction …
Imputation of Missing Values in Proteomics
What causes missing values in proteomics (and metabolomics) and how to assess several imputation methods.
Omics Playground V3 – A Fresh Look and Exciting New Features
Omics Playground V3:A Fresh Look and Exciting New Features Published on December 14th, 2023⏱ 9 min read Introduction We’re excited to announce the release of Version 3 of Omics Playground. As …
Three Main Challenges in Omics Data Analysis and the Future of Bioinformatics – Interview with Tommy Tang
Three Main Challenges in Omics Data Analysis and the Future of Bioinformatics – Interview with Ming Tommy Tang Published on December 12th, 2023⏱ 9 min read Introduction There are several challenging …
Experimental Design and Data Analysis: Common Bioinformatics Mistakes
Common Bioinformatics Data Analysis Mistakes Checklist of errors to avoid and recommendations for successful bioinformatic data analysis. Published on November 20th, 2023⏱ 9 min read Introduction In this blog article, we …
The Landscape of Bioinformatics Tools and the Importance of Interoperability for “End-to-end” Omics data Analysis
The Landscape of Bioinformatics Tools and the Importance of Interoperability for “End-to-end” Omics Data Analysis Published on November 20th, 2023 by Murat Akhmedov, CEO⏱ 9 min read Introduction Omics experiments involve …
Exploring Omics Playground: A Computational Biologist’s Review
Exploring Omics Playground: A Computational Biologist’s Evaluation Published on Nov 8, 2023Written by Murat Akhmedov, CEO ⏱ 8 min read I recently had the opportunity to interview Jonathan Landry, a computational …
The Evolution of Biodata Analysis and Visualization
The Evolution of Biodata Analysis and Visualization From Script to Reports to Interactive Dashboards Published on October 31st, 2023 Written by Murat Akhmedov, CEO⏱ 9 min read Introduction The enormous amounts …
Common Mistakes in Omics Experimental Design for Biologists
Common Mistakes in Omics Experimental Design for Biologists Published on October 18th, 2023Written by Axel Martinelli⏱ 5 min read Introduction Scientists frequently make mistakes in experimental design. The good news …
Top RNA Seq Service Providers for Your Experiment
Top RNA Seq Service Providers for Your Experiment Top CROs, their role in RNA-Seq data generation and how to choose the right one for your RNA-Seq experiment. Published on September …
Enabling Omics Data Analysis at Scale
Enabling Omics Data Analysis at Scale Bioinformatics Support to Understand Human Immunology Download the case study Goal The Institute for Research in Biomedicine (IRB) in Bellinzona stands out as an …
Accelerating Drug Repurposing with Intuitive and Easy-To-Use Omics Data Analytics
Accelerating Drug Repurposing with Intuitive and Easy-To-Use Omics Data Analytics Using Human Brain Organoids for Drug Screening. Download the case study Goal A leading interdisciplinary research institute in Boston with …
Build or Buy: Big Data Challenges in Transcriptomics and Proteomics
Build or Buy: Big Data Challenges in Omics Data Analysis Advantages and disadvantages of developing an in-house solution versus buying commercial bioinformatics omics tools for biotech and pharma companies. Published …
DNAnexus and BigOmics Analytics Join Forces to Improve Proteomics and Transcriptomics Data Visualization and Interpretation
DNAnexus and BigOmics Analytics Join Forces to Improve Proteomics and Transcriptomics Data Visualization and Interpretation Published on August 2nd, 2023by BigOmics Complete collaborative environment with intuitive interface addresses common analysis …
Omics Data Analysis for Novel Cancer Drug Discovery
Revolutionizing Novel Cancer Drug Discovery with Flexible, Trusted and User-Friendly Omics Data Analysis Download the case study Request a demo Goal Valerio Therapeutics is a clinical-stage biotechnology company developing novel …
Advances in Parkinson’s Disease Research and Michael J. Fox’s story
Advances in Parkinson’s Disease Research and Michael J. Fox’s Story Published on July 4th, 2023by Axel Martinelli, PhD ⏱ 7 min read Neurodegenerative Diseases – Can They Be Eradicated in Our …
Comparative analysis and Identification of Therapeutic Targets for Neurodegenerative Diseases: a Re-Analysis
Comparative analysis and Identification of Therapeutic Targets for Neurodegenerative Diseases: a Re-Analysis Learn about the similarities and differences between Alzheimer’s disease and Parkinson’s disease and how to identify therapeutic targets …
The Application of RNA-Seq and Proteomics in Cancer Research
The Application of RNA-Seq and Proteomics in Cancer Research Published on June 20th, 2023by Axel Martinelli, PhD ⏱ 5 min read Introduction Pharmaceutical companies are under intense pressure to succeed in …
Revolutionary Cancer Research Breakthroughs
Revolutionary Cancer Research Breakthroughs The impact of RNA-seq and Proteomics technologies in advancing cancer treatments, improving therapies and driving cancer research breakthroughs. Published on June 6th, 2023by Axel Martinelli, PhD …
RNA-seq transcriptome analysis of the anti-inflammatory effect of artesunate on cerebral malaria
RNA-seq transcriptome analysis of the anti-inflammatory effect of artesunate on cerebral malaria Re-Analysis Published on April 25th, 2023by Axel Martinelli, PhD ⏱ 11 min read Introduction to the Cerebral Malaria …
9 factors you should consider when choosing RNA-seq analysis and visualization software
9 factors you should consider when choosing RNA-seq analysis and visualization software Published on April 20th, 2023 by BigOmics ⏱ 11 min read Commercial RNA-seq data analysis software allows researchers, biotechnology, …
How to convert FASTQ files into read count tables using Galaxy
How to Convert FASTQ Files Into Read Count Tables Using Galaxy Published on August 2nd, 2022 by Axel Martinelli This short guide is meant for biologists with little or no …
From sample to data to discovery: how to get the most out of your experiments
Omics data is becoming ubiquitous both in biological and, increasingly, medical research. Rapid developments in reagents, sequencing technologies and analysis are constantly pushing down costs while increasing the amount of …
Profilin 1 and its role in proteasome inhibitors resistance
Profilin 1 and its role in proteasome inhibitors resistance Published on May 19th, 2022Written by Axel Martinelli⏱ 2 min read Introduction Browsing through the most recent proteomics dataset on the …
BigOmics closes Pre-Series A with additional investment from Eppendorf
Lugano, March 17, 2022 – BigOmics Analytics, a Swiss biodata analytics startup, announces raising additional funding from Eppendorf, a leading life science company that develops and sells instruments, consumables and …
The Role of Osteopontin on Prostatic Fibrosis and Inflammation
The Role of Osteopontin on Prostatic Fibrosis and Inflammation Re-analysis of an RNA-Seq dataset looking at the osteopontin function in prostate fibrosis and identifying potential therapeutic targets Last updated on …
BigOmics to assist Remix Therapeutics with omics data analysis in their mission to reprogram RNA processing
Remix Therapeutics is a Boston-based biotechnology company developing novel small molecule therapies for reprogramming RNA processing and treating disease in entirely new ways. As protein targeting therapies reach the limits …
BigOmics Raises $1.85M to Revolutionize Omics Data Analytics
Bellinzona, Switzerland, December 10, 2021 – BigOmics Analytics SA (“BigOmics”), a Swiss biodata analytics startup, announced today that it raised a total of $1.85 million in financing. This funding will …
Meet us at BioData & Genomics Live World Congress!
We are excited to announce that we are exhibitors at the BioData & Genomics Live World Congress in Basel. BioData World covers big data in pharmaceutical development and healthcare. Genomics …
The Role of the Microbiome on Social Interactions in Mice: RNA-Seq Data Analysis
The Role of the Microbiome on Social Interactions in Mice: RNA-Seq Data Analysis Last updated on December 6th, 2024Published on October 21st, 2021Written by Axel Martinelli⏱ 9 min read Introduction The …
Bioinformatic Platforms: Bridging the Gap Between Biologists and Bioinformaticians
Bioinformatic Platforms: Bridging the Gap Between Biologists and Bioinformaticians Written by Axel Martinelli Last updated on December 13, 2024Published on August 26, 2021⏱ 5 min read Introduction The analysis of …
Meet BigOmics at the [BC]2 Conference!
We are excited to announce that BigOmics will be sponsoring the BC2 conference that will take place at the Congress Center Basel and online from 13 – 15 September 2021. …
Glucocorticoid Resistance in Multiple Myeloma: a Dataset Re-analysis
RNA-Seq Data Re-Analysis Glucocorticoid Resistance in Multiple Myeloma Withaferin A and BTK Inhibitors: Analyzing Drug Resistance Mechanisms in Multiple Myeloma Dataset Written by Axel MartinelliLast updated on December 13th, 2024Published …
In-house or out-house: Is it time to outsource bioinformatics?
In-house or out-house: Is it time to outsource bioinformatics? Exploring how commercialization can address the challenges faced by bioinformatics in academia, while paving the way for more efficient and specialized …
Now Hiring – Account Executive
Achieving sales, account growth, and client success objectives within a geographical territory of mid-market Biotech accounts. This includes identifying and qualifying opportunities and efficiently leveraging resources in order to bring opportunities to successful conclusions.
Omics Playground 4 – Discover the Latest Features
Omics Playground 4 – The Newest Key Features Discover the key features available in the new beta version of Omics Playground. Published on May 20, 2025. Introduction The beta version …