To investigate choroidal thickness using enhanced-depth imaging optical coherence tomography in p... more To investigate choroidal thickness using enhanced-depth imaging optical coherence tomography in paediatric patients with adenotonsillar hypertrophy, with comparison to healthy children, three months after adenotonsillectomy. The patients were assigned to three groups: an adenotonsillar hypertrophy group, an adenotonsillectomy group and a healthy control group. In all groups, subfoveal, temporal and nasal choroidal thickness measurements were taken. In the subfoveal, temporal and nasal regions, choroidal tissue was found to be significantly thinner in adenotonsillar hypertrophy children than healthy children (p = 0.012, p = 0.027 and p = 0.020). The subfoveal and temporal choroidal thickness measurements of adenotonsillar hypertrophy group cases were significantly decreased compared to those in the adenotonsillectomy group (p = 0.038 and p = 0.048). There was a significant association between decreased choroidal thickness and adenotonsillar hypertrophy. Adenotonsillar hypertrophy may play an important role in decreased choroidal thickness.
Objective:An examination was conducted of the number, level, clinical association and treatment a... more Objective:An examination was conducted of the number, level, clinical association and treatment approaches for vertebral arterial loop formation in patients with this condition with and without concurrent cervicogenic dizziness, and classified them according to the vertebral artery segment in which it was present.Method:A cross-sectional retrospective study.Results:Thirty-seven patients who had undergone double-sided magnetic resonance angiography were examined; vertebral arterial loop formation was observed at only 1 level in 26 patients and at several levels in 9 patients. Segment one (V1) was involved in 78.3 per cent of cases and segment two (V2) was involved in 21.6 per cent. Symptoms in patients with vertebral arterial loop formation included: positional vertigo, in 100 per cent; and pulsatile tinnitus, in 83.7 per cent.Conclusion:Loop formation at the vertebral artery was observed most often on the proximal side in patients with cervicogenic dizziness (78.3 per cent). The incidence on the left side was twice as high as on the right side.
ObjectiveSuperior semicircular canal dehiscence is an uncommon neurotological disorder in which t... more ObjectiveSuperior semicircular canal dehiscence is an uncommon neurotological disorder in which the petrous temporal bone overlying the superior semicircular canal lacks bone. Its most common symptoms include amplification of internal sounds, autophony, tinnitus, sound- and pressure-induced vertigo, hyperacusis, oscillopsia, and hearing loss. This video presentation aimed to demonstrate endoscopic-assisted repair of superior semicircular canal dehiscence with middle fossa craniotomy.MethodEleven patients with superior semicircular canal dehiscence, verified with temporal computed tomography, were enrolled in the study.ResultAn endoscopy-assisted middle fossa approach was applied to all patients. Superior semicircular canal dehiscence was successfully repaired with an endoscope in 11 patients.ConclusionEndoscopic-assisted repair of superior semicircular canal dehiscence may be a superior approach compared with binocular operative microscopy.
Bu çalışmanın amacı, paranazal sinüs anatomik varyasyonlu hastalarda alerjik rinit sıklığını araş... more Bu çalışmanın amacı, paranazal sinüs anatomik varyasyonlu hastalarda alerjik rinit sıklığını araştırmaktır. YÖNTEM ve GEREÇLER: En az bir paranazal sinüs anatomik varyasyonu olan 124 hasta çalışma grubunu, hiçbir paranazal sinüs anatomik varyasyonu olmayan 86 kişi kontrol grubunu oluşturdu. Gruplar hakkında bilgisi olmayan bir araştırmacı çalışmaya katılan bütün hastaların detaylı hikayesini aldı ve alerjik rinitin major bulguları açısından sorgulayıp kaydetti. Tüm hastalar kulak burun boğaz fizik muayenesinden geçirildi. Yine gruplar hakkında bilgisi olmayan başka bir araştırmacı da hastaların deri prick testlerini yaptı. BULGULAR: Kontrol grubunda 17 hastaya (%19,8) alerjik rinit tanısı konulmuşken, çalışma grubunda 35 hastaya (%28,2) alerjik rinit tanısı konuldu. Alerjik rinitli hastalarda istatistiksel olarak anlamlı düzeyde daha sık agger nasi, hipertrofik etmoid bulla ve konka büllosa mevcuttu. Ayrıca alerjik riniti olmayanlara göre alerjik rinitli hastalarda istatistiksel olarak anlamlı düzeyde daha fazla sayıda anatomik varyasyon saptandı. TARTIŞMA ve SONUÇ: Paranazal sinüs anatomik varyasyon sayısının artmış alerjik rinit insidansı ile anlamlı derecede ilişkili olduğu gözlendi.
Bu çalışmada tekrar eden tonsilit nedeniyle tonsillektomi geçiren çocuklarda serum, tonsil yüzey ... more Bu çalışmada tekrar eden tonsilit nedeniyle tonsillektomi geçiren çocuklarda serum, tonsil yüzey epitel doku ve parankim melatonin düzeyleri karşılaştırıldı. Hastalar ve Yöntemler: Çalışmaya tonsillektomi cerrahisi planlanan 33 pediatrik hasta (17 erkek, 16 kız; ort. yaş 7.3 yıl; dağılım, 3-10 yıl) dahil edildi. Hastalardan 5 mL venöz kan örneği ve 25 g iki farklı tonsil doku, parankim ve kapsül toplandı ve saklandı. Plazma ve doku örneklerindeki melatoninin saptanmasında yüksek performanslı sıvı kromatografisi kullanıldı. Bulgular: Tonsil yüzey doku melatonin düzeyleri eş zamanlı plazma melatonin düzeylerinden daha düşük idi (p<0.0135). Plazma melatonin düzeyleri eş zamanlı tonsil parankim doku melatonin düzeylerinden daha yüksek idi (p<0.016). Tonsil yüzey doku melatonin düzeyleri eş zamanlı tonsil parankim doku melatonin düzeylerinden daha düşük idi (p<0.002). Sonuç: Kronik tonsilitli çocuklarda plazma melatonin konsantrasyonları ve tonsil yüzey epitel doku ve parankim melatonin konsantrasyonları düşük idi. Bu bulguya göre, tonsillektomi için endike hastalarda serum melatonin düzeylerinin kontrol edilmesini önerebiliriz. Anahtar sözcükler: İmmünmodülatör, melatonin düzeyi, tekrar eden tonsilit, tonsillektomi. Objectives: This study aims to compare the serum, tonsil surface epithelial tissue and parenchyma levels of melatonin in children who underwent tonsillectomy due to recurrent tonsillitis. The study included 33 pediatric patients (17 males, 16 females; mean age 7.3 years; range, 3 to 10 years) scheduled for tonsillectomy surgery. Five milliliter venous blood samples and 25 g of two different types of tonsil tissues, parenchyma and capsule were collected from the patients and stored. High performance liquid chromatography was used for the determination of melatonin in plasma and tissue samples. The tonsil surface tissue levels of melatonin were lower than the simultaneous plasma levels of melatonin (p<0.0135). The plasma levels of melatonin were higher than the simultaneous tonsil parenchyma tissue levels of melatonin (p<0.016). The tonsil surface tissue levels of melatonin were lower than the simultaneous tonsil parenchyma tissue levels of melatonin (p<0.002). The plasma concentrations of melatonin and tonsil surface epithelial tissue and parenchyma concentrations of melatonin in children with chronic tonsillitis were low. According to this finding, we may recommend serum levels of melatonin to be checked in patients indicated for tonsillectomy.
Background: Hyperbaric Oxygen therapy is recommended as an adjuvant therapy for diabetic neuropat... more Background: Hyperbaric Oxygen therapy is recommended as an adjuvant therapy for diabetic neuropathy. To investigate olfactory dysfunction and show the effectiveness of hyperbaric oxygen treatment in patients with type 2 diabetic neuropathy. Material and Methods: Patients diagnosed with Type 2 DM and diabetic neuropathy were included in the group 1. Patients of Group 1 were administered with a hyperbaric oxygen therapy for 30 sessions and patients who returned for a check up following 30 sessions were incorporated into the Group 2. Healthy volunteers with no medical problems were included in the study as a control group (Group 3). Connecticut Chemosensory Clinical Research (CCCRC) test and the subjective visual analog scale (VAS; 0-100) were utilized to evaluate the olfactory function. Results: There was a statistically significant difference both between the control group and the patient group as well as before and after the HBO therapy in terms of total CCCRC scoring averages and VAS Scoring averages. When compared to normal individuals, type 2 diabetic neuropathy can cause an olfactory dysfunction, and a statistically significant improvement in olfaction can be obtained with HBO therapy. This is the first study demonstrating that the HBO therapy can play a role in treating olfactory dysfunctions suffered by the patients with diabetic olfactory neuropathies.
To investigate choroidal thickness using enhanced-depth imaging optical coherence tomography in p... more To investigate choroidal thickness using enhanced-depth imaging optical coherence tomography in paediatric patients with adenotonsillar hypertrophy, with comparison to healthy children, three months after adenotonsillectomy. The patients were assigned to three groups: an adenotonsillar hypertrophy group, an adenotonsillectomy group and a healthy control group. In all groups, subfoveal, temporal and nasal choroidal thickness measurements were taken. In the subfoveal, temporal and nasal regions, choroidal tissue was found to be significantly thinner in adenotonsillar hypertrophy children than healthy children (p = 0.012, p = 0.027 and p = 0.020). The subfoveal and temporal choroidal thickness measurements of adenotonsillar hypertrophy group cases were significantly decreased compared to those in the adenotonsillectomy group (p = 0.038 and p = 0.048). There was a significant association between decreased choroidal thickness and adenotonsillar hypertrophy. Adenotonsillar hypertrophy may play an important role in decreased choroidal thickness.
Objective:An examination was conducted of the number, level, clinical association and treatment a... more Objective:An examination was conducted of the number, level, clinical association and treatment approaches for vertebral arterial loop formation in patients with this condition with and without concurrent cervicogenic dizziness, and classified them according to the vertebral artery segment in which it was present.Method:A cross-sectional retrospective study.Results:Thirty-seven patients who had undergone double-sided magnetic resonance angiography were examined; vertebral arterial loop formation was observed at only 1 level in 26 patients and at several levels in 9 patients. Segment one (V1) was involved in 78.3 per cent of cases and segment two (V2) was involved in 21.6 per cent. Symptoms in patients with vertebral arterial loop formation included: positional vertigo, in 100 per cent; and pulsatile tinnitus, in 83.7 per cent.Conclusion:Loop formation at the vertebral artery was observed most often on the proximal side in patients with cervicogenic dizziness (78.3 per cent). The incidence on the left side was twice as high as on the right side.
ObjectiveSuperior semicircular canal dehiscence is an uncommon neurotological disorder in which t... more ObjectiveSuperior semicircular canal dehiscence is an uncommon neurotological disorder in which the petrous temporal bone overlying the superior semicircular canal lacks bone. Its most common symptoms include amplification of internal sounds, autophony, tinnitus, sound- and pressure-induced vertigo, hyperacusis, oscillopsia, and hearing loss. This video presentation aimed to demonstrate endoscopic-assisted repair of superior semicircular canal dehiscence with middle fossa craniotomy.MethodEleven patients with superior semicircular canal dehiscence, verified with temporal computed tomography, were enrolled in the study.ResultAn endoscopy-assisted middle fossa approach was applied to all patients. Superior semicircular canal dehiscence was successfully repaired with an endoscope in 11 patients.ConclusionEndoscopic-assisted repair of superior semicircular canal dehiscence may be a superior approach compared with binocular operative microscopy.
Bu çalışmanın amacı, paranazal sinüs anatomik varyasyonlu hastalarda alerjik rinit sıklığını araş... more Bu çalışmanın amacı, paranazal sinüs anatomik varyasyonlu hastalarda alerjik rinit sıklığını araştırmaktır. YÖNTEM ve GEREÇLER: En az bir paranazal sinüs anatomik varyasyonu olan 124 hasta çalışma grubunu, hiçbir paranazal sinüs anatomik varyasyonu olmayan 86 kişi kontrol grubunu oluşturdu. Gruplar hakkında bilgisi olmayan bir araştırmacı çalışmaya katılan bütün hastaların detaylı hikayesini aldı ve alerjik rinitin major bulguları açısından sorgulayıp kaydetti. Tüm hastalar kulak burun boğaz fizik muayenesinden geçirildi. Yine gruplar hakkında bilgisi olmayan başka bir araştırmacı da hastaların deri prick testlerini yaptı. BULGULAR: Kontrol grubunda 17 hastaya (%19,8) alerjik rinit tanısı konulmuşken, çalışma grubunda 35 hastaya (%28,2) alerjik rinit tanısı konuldu. Alerjik rinitli hastalarda istatistiksel olarak anlamlı düzeyde daha sık agger nasi, hipertrofik etmoid bulla ve konka büllosa mevcuttu. Ayrıca alerjik riniti olmayanlara göre alerjik rinitli hastalarda istatistiksel olarak anlamlı düzeyde daha fazla sayıda anatomik varyasyon saptandı. TARTIŞMA ve SONUÇ: Paranazal sinüs anatomik varyasyon sayısının artmış alerjik rinit insidansı ile anlamlı derecede ilişkili olduğu gözlendi.
Bu çalışmada tekrar eden tonsilit nedeniyle tonsillektomi geçiren çocuklarda serum, tonsil yüzey ... more Bu çalışmada tekrar eden tonsilit nedeniyle tonsillektomi geçiren çocuklarda serum, tonsil yüzey epitel doku ve parankim melatonin düzeyleri karşılaştırıldı. Hastalar ve Yöntemler: Çalışmaya tonsillektomi cerrahisi planlanan 33 pediatrik hasta (17 erkek, 16 kız; ort. yaş 7.3 yıl; dağılım, 3-10 yıl) dahil edildi. Hastalardan 5 mL venöz kan örneği ve 25 g iki farklı tonsil doku, parankim ve kapsül toplandı ve saklandı. Plazma ve doku örneklerindeki melatoninin saptanmasında yüksek performanslı sıvı kromatografisi kullanıldı. Bulgular: Tonsil yüzey doku melatonin düzeyleri eş zamanlı plazma melatonin düzeylerinden daha düşük idi (p<0.0135). Plazma melatonin düzeyleri eş zamanlı tonsil parankim doku melatonin düzeylerinden daha yüksek idi (p<0.016). Tonsil yüzey doku melatonin düzeyleri eş zamanlı tonsil parankim doku melatonin düzeylerinden daha düşük idi (p<0.002). Sonuç: Kronik tonsilitli çocuklarda plazma melatonin konsantrasyonları ve tonsil yüzey epitel doku ve parankim melatonin konsantrasyonları düşük idi. Bu bulguya göre, tonsillektomi için endike hastalarda serum melatonin düzeylerinin kontrol edilmesini önerebiliriz. Anahtar sözcükler: İmmünmodülatör, melatonin düzeyi, tekrar eden tonsilit, tonsillektomi. Objectives: This study aims to compare the serum, tonsil surface epithelial tissue and parenchyma levels of melatonin in children who underwent tonsillectomy due to recurrent tonsillitis. The study included 33 pediatric patients (17 males, 16 females; mean age 7.3 years; range, 3 to 10 years) scheduled for tonsillectomy surgery. Five milliliter venous blood samples and 25 g of two different types of tonsil tissues, parenchyma and capsule were collected from the patients and stored. High performance liquid chromatography was used for the determination of melatonin in plasma and tissue samples. The tonsil surface tissue levels of melatonin were lower than the simultaneous plasma levels of melatonin (p<0.0135). The plasma levels of melatonin were higher than the simultaneous tonsil parenchyma tissue levels of melatonin (p<0.016). The tonsil surface tissue levels of melatonin were lower than the simultaneous tonsil parenchyma tissue levels of melatonin (p<0.002). The plasma concentrations of melatonin and tonsil surface epithelial tissue and parenchyma concentrations of melatonin in children with chronic tonsillitis were low. According to this finding, we may recommend serum levels of melatonin to be checked in patients indicated for tonsillectomy.
Background: Hyperbaric Oxygen therapy is recommended as an adjuvant therapy for diabetic neuropat... more Background: Hyperbaric Oxygen therapy is recommended as an adjuvant therapy for diabetic neuropathy. To investigate olfactory dysfunction and show the effectiveness of hyperbaric oxygen treatment in patients with type 2 diabetic neuropathy. Material and Methods: Patients diagnosed with Type 2 DM and diabetic neuropathy were included in the group 1. Patients of Group 1 were administered with a hyperbaric oxygen therapy for 30 sessions and patients who returned for a check up following 30 sessions were incorporated into the Group 2. Healthy volunteers with no medical problems were included in the study as a control group (Group 3). Connecticut Chemosensory Clinical Research (CCCRC) test and the subjective visual analog scale (VAS; 0-100) were utilized to evaluate the olfactory function. Results: There was a statistically significant difference both between the control group and the patient group as well as before and after the HBO therapy in terms of total CCCRC scoring averages and VAS Scoring averages. When compared to normal individuals, type 2 diabetic neuropathy can cause an olfactory dysfunction, and a statistically significant improvement in olfaction can be obtained with HBO therapy. This is the first study demonstrating that the HBO therapy can play a role in treating olfactory dysfunctions suffered by the patients with diabetic olfactory neuropathies.
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