The microbial transformation of (؉)-catechin (1) and (؊)epicatechin (2) by endophytic fungi isola... more The microbial transformation of (؉)-catechin (1) and (؊)epicatechin (2) by endophytic fungi isolated from a tea plant was investigated. It was found that the endophytic filamentous fungus Diaporthe sp. transformed them (1, 2) into the 3,4-cis-dihydroxyflavan derivatives, (؉)-(2R,3S,4S)-3,4,5,7,3,4-hexahydroxyflavan (3) and (؊)-(2R,3R,4R)-3,4,5,7,3,4-hexahydroxyflavan (7), respectively, whereas (؊)-catechin (ent-1) and (؉)epicatechin (ent-2) with a 2S-phenyl group resisted the biooxidation.
The major biotransformation product were isolated and purified through column chromatography tech... more The major biotransformation product were isolated and purified through column chromatography techniques using Sephadex LH-20 and silica gel. The chemical structure of the major product were elucidated as (-)-2R,3S-dihydromyricetin based on their IR, FAB-MS, 1D-and 2D-NMR spectra.
The fungus AFK-8 is one of endophytic filamentous fungus isolated from young stems of kayu kuning... more The fungus AFK-8 is one of endophytic filamentous fungus isolated from young stems of kayu kuning [Archangelesia flava (L.) Merr.]. The ethyl acetate extract derived from fungus culture shows their antibiotic activity tested against bacteria and fungi on a disc diffusion ...
Totaly eighteen kinds of endophytic fungi have been isolated from the young stems of kayu kuning ... more Totaly eighteen kinds of endophytic fungi have been isolated from the young stems of kayu kuning [Archangelisia flava (L.) Merr.] collected from Bogor Botanic Garden. All of isolated fungi have been screened for their capability to transform the host plant alkaloid berberine ...
An amlysi, by gas chromatogrryh and mass spectrcphototncter on the chcmical compoun^ds of Chtonwl... more An amlysi, by gas chromatogrryh and mass spectrcphototncter on the chcmical compoun^ds of Chtonwlacna odorata weed gtucted by luxaw was conducted. TIw results irdicued there u,cne 15 components in tlw iiowct five components in thi baves, 27 conponcnts in tlu stem and I5 componcnts in the root parc. In total tlure was 48 components in plart wene identified as allcantes, fatty acids, all@Ioi{ stercid and hydrazine. Some of the compounds were act cts alleloplnty and nxic to animals.
The microbial transformation of (؉)-catechin (1) and (؊)epicatechin (2) by endophytic fungi isola... more The microbial transformation of (؉)-catechin (1) and (؊)epicatechin (2) by endophytic fungi isolated from a tea plant was investigated. It was found that the endophytic filamentous fungus Diaporthe sp. transformed them (1, 2) into the 3,4-cis-dihydroxyflavan derivatives, (؉)-(2R,3S,4S)-3,4,5,7,3,4-hexahydroxyflavan (3) and (؊)-(2R,3R,4R)-3,4,5,7,3,4-hexahydroxyflavan (7), respectively, whereas (؊)-catechin (ent-1) and (؉)epicatechin (ent-2) with a 2S-phenyl group resisted the biooxidation.
The major biotransformation product were isolated and purified through column chromatography tech... more The major biotransformation product were isolated and purified through column chromatography techniques using Sephadex LH-20 and silica gel. The chemical structure of the major product were elucidated as (-)-2R,3S-dihydromyricetin based on their IR, FAB-MS, 1D-and 2D-NMR spectra.
The fungus AFK-8 is one of endophytic filamentous fungus isolated from young stems of kayu kuning... more The fungus AFK-8 is one of endophytic filamentous fungus isolated from young stems of kayu kuning [Archangelesia flava (L.) Merr.]. The ethyl acetate extract derived from fungus culture shows their antibiotic activity tested against bacteria and fungi on a disc diffusion ...
Totaly eighteen kinds of endophytic fungi have been isolated from the young stems of kayu kuning ... more Totaly eighteen kinds of endophytic fungi have been isolated from the young stems of kayu kuning [Archangelisia flava (L.) Merr.] collected from Bogor Botanic Garden. All of isolated fungi have been screened for their capability to transform the host plant alkaloid berberine ...
An amlysi, by gas chromatogrryh and mass spectrcphototncter on the chcmical compoun^ds of Chtonwl... more An amlysi, by gas chromatogrryh and mass spectrcphototncter on the chcmical compoun^ds of Chtonwlacna odorata weed gtucted by luxaw was conducted. TIw results irdicued there u,cne 15 components in tlw iiowct five components in thi baves, 27 conponcnts in tlu stem and I5 componcnts in the root parc. In total tlure was 48 components in plart wene identified as allcantes, fatty acids, all@Ioi{ stercid and hydrazine. Some of the compounds were act cts alleloplnty and nxic to animals.
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