Last Updated: December 2025

>At Athaca, we believe advanced AI systems especially those applied to healthcare and life sciences must be built and deployed responsibly. This page outlines our principles and practices for the ethical use of artificial intelligence, data stewardship, and clinical responsibility.

1. Purpose and Scope

Athaca develops AI systems designed to simulate disease dynamics and patient trajectories using synthetic data and computational models, often referred to as Clinical World Models.

Our technology is intended to support research, education, feasibility analysis, and decision-support exploration not to replace clinical judgment, regulatory review, or real-world evidence generation.

2. No Clinical Decision-Making

Athaca's AI systems:

• • Do not provide medical advice, diagnoses, or treatment recommendations
• • Are not intended for direct clinical decision-making
• • Are not substitutes for clinical trials, physician expertise, or regulatory approval
• • Are not FDA-cleared or approved medical devices

All outputs are synthetic, probabilistic, and research-oriented and must be interpreted accordingly.

3. Synthetic-First Data Philosophy

Athaca is built on a synthetic-first approach to data use:

• • We do not require or accept real patient data through our website
• • We prohibit the upload or use of Protected Health Information (PHI)
• • Our simulations generate synthetic cohorts that do not correspond to real individuals
• • Synthetic outputs are designed to reduce privacy risk while enabling research insight

This approach is foundational to our commitment to privacy, safety, and scalability.

4. Data Stewardship & Privacy

Athaca is committed to responsible data handling:

• • We collect only limited, non-sensitive information through our website
• • We do not knowingly collect health data or sensitive personal information
• • Website interaction data is used only in aggregated or non-identifiable form
• • Data practices are governed by our Privacy Policy

Enterprise or research collaborations involving data are governed by separate contractual agreements with appropriate safeguards.

5. Transparency & Explainability

We strive to design AI systems that are:

• • Transparent about their intended use and limitations
• • Clear that outputs are models, not ground truth
• • Explainable at a conceptual level for scientific and educational users

We actively avoid overstating model certainty or predictive authority.

6. Bias Awareness & Model Limitations

Athaca acknowledges that all models have limitations.

Our approach includes:

• • Continuous evaluation of model behavior across populations and scenarios
• • Awareness of potential bias introduced by source data or modeling assumptions
• • Ongoing research into robustness, generalizability, and fairness

No model output should be interpreted in isolation or without domain expertise.

7. Human Oversight

Athaca's technology is designed to augment human expertise, not replace it.

Responsible use requires:

• • Human review and interpretation
• • Domain-appropriate expertise
• • Contextual understanding of model assumptions and constraints

Users are responsible for ensuring appropriate oversight in any research or evaluation setting.

8. Educational & Research Access

Athaca supports educational use, including by students and researchers, provided that:

• • Use remains informational or exploratory
• • Outputs are not used for real-world clinical decisions
• • Prohibited data (e.g., real patient data) is not introduced

We believe responsible access supports learning while maintaining safeguards.

9. Continuous Improvement & Governance

Responsible AI is an ongoing process. Athaca commits to:

• • Monitoring evolving regulatory guidance
• • Updating practices as standards mature
• • Incorporating feedback from scientific, clinical, and regulatory stakeholders
• • Suspending or modifying capabilities if responsible use cannot be ensured

10. Questions or Concerns

We welcome dialogue on responsible AI.

If you have questions, concerns, or believe our technology is being used inappropriately, please contact us:

Athaca Corporation

1907 Rio SecoLeander, TX 78641

Email: [email protected]