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In this perspective, m-Health technologies offer an unobtrusive and rapid solution for home monitoring. We developed a multi-scale method based on motion signal extracted from an unobtrusive device to evaluate sleep behavior. Data used in this study were collected during two different acquisition campaigns by using a Pressure Bed Sensor (PBS). The first one was carried out with 22 subjects for sleep problems, and the second one comprises 11 healthy shift workers. All underwent full PSG and PBS recordings. The algorithm consists of extracting sleep quality and fragmentation indexes correlating to clinical metrics. In particular, the method classifies sleep windows of 1-s of the motion signal into: displacement (DI), quiet sleep (QS), disrupted sleep (DS) and absence from the bed (ABS). QS proved to be positively correlated (0.72\u00b10.014) to Sleep Efficiency (SE) and DS\/DI positively correlated (0.85\u00b10.007) to the Apnea-Hypopnea Index (AHI). The work proved to be potentially helpful in the early investigation of sleep in the home environment. The minimized intrusiveness of the device together with a low complexity and good performance might provide valuable indications for the home monitoring of sleep disorders and for subjects\u2019 awareness.<\/jats:p>","DOI":"10.3390\/s22145295","type":"journal-article","created":{"date-parts":[[2022,7,18]],"date-time":"2022-07-18T01:53:22Z","timestamp":1658109202000},"page":"5295","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Multi-Scale Evaluation of Sleep Quality Based on Motion Signal from Unobtrusive Device"],"prefix":"10.3390","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8237-2443","authenticated-orcid":false,"given":"Davide","family":"Coluzzi","sequence":"first","affiliation":[{"name":"Dipartimento di Elettronica, Informazione e Bioingegneria Politecnico di Milano, 20133 Milano, Italy"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2978-1704","authenticated-orcid":false,"given":"Giuseppe","family":"Baselli","sequence":"additional","affiliation":[{"name":"Dipartimento di Elettronica, Informazione e Bioingegneria Politecnico di Milano, 20133 Milano, Italy"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8290-7460","authenticated-orcid":false,"given":"Anna Maria","family":"Bianchi","sequence":"additional","affiliation":[{"name":"Dipartimento di Elettronica, Informazione e Bioingegneria Politecnico di Milano, 20133 Milano, Italy"}]},{"given":"Guillermina","family":"Guerrero-Mora","sequence":"additional","affiliation":[{"name":"Unidad Acad\u00e9mica Multidisciplinaria Zona Media, Universidad Aut\u00f3noma de San Luis Potos\u00ed, San Luis Potos\u00ed 79615, Mexico"}]},{"given":"Juha M.","family":"Kortelainen","sequence":"additional","affiliation":[{"name":"VTT Technical Research Center of Finland, Tampere, Finland"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0202-8392","authenticated-orcid":false,"given":"Mirja L.","family":"Tenhunen","sequence":"additional","affiliation":[{"name":"Department of Clinical Neurophysiology, Medical Imaging Centre, Pirkanmaa Hospital District, Tampere, Finland"},{"name":"Department of Medical Physics, Tampere University Hospital, Medical Imaging Centre, Pirkanmaa Hospital District, Tampere, Finland"}]},{"given":"Martin O.","family":"Mendez","sequence":"additional","affiliation":[{"name":"Dipartimento di Elettronica, Informazione e Bioingegneria Politecnico di Milano, 20133 Milano, Italy"},{"name":"Laboratorio Nacional\u2014Centro de Investigaci\u00f3n, Instrumentaci\u00f3n e Imagenolog\u00eda M\u00e9dica, Facultad de Ciencias, Universidad Aut\u00f3noma de San Luis Potos\u00ed, San Luis Potos\u00ed 78210, Mexico"}]}],"member":"1968","published-online":{"date-parts":[[2022,7,15]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"151","DOI":"10.2147\/NSS.S134864","article-title":"Short- and long-term health consequences of sleep disruption","volume":"9","author":"Medic","year":"2017","journal-title":"Nat. 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