Ritu Roy
PROGR ANL 3
HDF Comprehensive Cancer Ctr
School of Medicine

Publications (85)

Top publication keywords:
Epigenesis, GeneticRenin-Angiotensin SystemComparative Genomic HybridizationLeukemia, Biphenotypic, AcuteNeoplasmsFatiguePrecursor T-Cell Lymphoblastic Leukemia-LymphomaGene Expression ProfilingAntineoplastic Agents, ImmunologicalCarotenoidsNeoplastic Cells, CirculatingPrecursor Cell Lymphoblastic Leukemia-LymphomaGene Expression Regulation, LeukemicDNA MethylationSingle-Cell Analysis

• A Data-Driven Epigenetic Characterization of Morning Fatigue Severity in Oncology Patients Receiving Chemotherapy: Associations With Epigenetic Age Acceleration, Blood Cell Types, and Expression-Associated Methylation.
  Cancer medicine 2025 Le C, Lewis M, Harris CS, Berger L, Chavez-Iglesias E, Morse L, Sucher A, Roy R, Olshen A, Hammer MJ, Paul S, Wallhagen M, Chan R, Sayer M, Yom S, Cho NW, Chan A, Levine J, Dhruva A, Miaskowski C, …
• SNACS: a tool for demultiplexing single-cell DNA sequencing data.
  Bioinformatics (Oxford, England) 2025 Kennedy VE, Roy R, Peretz CAC, Koh A, Tran E, Smith CC, Olshen AB
• Early adverse symptoms to predict response to treatment among patients in the I-SPY trial.
  Journal of Clinical Oncology 2025 Amrita Basu, Saumya Umashankar, Denise M. Wolf, Christina Yau, Ritu Roy, Kathryn Jean Ruddy, Anne Hudson Blaes, Adam B. Olshen, Angela DeMichele, Jane Perlmutter, Douglas Yee, Nola Hylton, Laura van t…
• Perturbations in the neuroactive ligand-receptor interaction and renin angiotensin system pathways are associated with cancer-related cognitive impairment.
  Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 2025 Chan RJ, Walker A, Vardy J, Chan A, Oppegaard K, Conley YP, Paul SM, Kober KM, Harris C, Shin J, Morse L, Roy R, Olshen A, Hammer MJ, Levine JD, Miaskowski C
• Identifying symptom clusters associated with acute and chronic fatigue in patients with breast cancer treated with neoadjuvant therapy on the I-SPY 2 trial.
  Journal of Clinical Oncology 2024 Amrita Basu, Saumya Umashankar, Denise M. Wolf, Hannah Chay, Ritu Roy, Diane Heditsian, Thelma Brown, Beverly Parker, Abigail Abikoye, Susie Brain, Tina J. Hieken, Kathryn Jean Ruddy, Candace Bavette …

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• Self-reported cancer-related cognitive impairment is associated with perturbed neurotransmission pathways.
  Journal of neural transmission (Vienna, Austria : 1996) 2024 Oppegaard KR, Conley YP, Paul S, Cooper B, Harris CS, Shin J, Morse L, Levine JD, Cartwright F, Roy R, Melisko M, Kober KM, Hammer MJ, Miaskowski C
• Multiomic single cell sequencing identifies stemlike nature of mixed phenotype acute leukemia.
  Nature communications 2024 Peretz CAC, Kennedy VE, Walia A, Delley CL, Koh A, Tran E, Clark IC, Hayford CE, D'Amato C, Xue Y, Fontanez KM, May-Zhang AA, Smithers T, Agam Y, Wang Q, Dai HP, Roy R, Logan AC, Perl AE, Abate A, …
• Neurodegenerative disease pathways are perturbed in patients with cancer who self-report cognitive changes and anxiety: A pathway impact analysis.
  Cancer 2024 Oppegaard KR, Mayo SJ, Armstrong TS, Dokiparthi V, Melisko M, Levine JD, Olshen AB, Anguera JA, Roy R, Paul S, Cooper B, Conley YP, Hammer MJ, Miaskowski C, Kober KM
• Perturbations in inflammatory pathways are associated with shortness of breath profiles in oncology patients receiving chemotherapy.
  Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 2024 Shin J, Miaskowski C, Wong ML, Yates P, Olshen AB, Roy R, Dokiparthi V, Cooper B, Paul S, Conley YP, Levine JD, Hammer MJ, Kober K
• Torch-eCpG: a fast and scalable eQTM mapper for thousands of molecular phenotypes with graphical processing units.
  BMC bioinformatics 2024 Kober KM, Berger L, Roy R, Olshen A
• Abstract B095: Leukemia inhibitory factor fosters tumor growth in KRAS-driven pancreatic ductal adenocarcinoma.
  Cancer Research 2024 Lisa Miller-Phillips, Imene Boukhalfa Hanafi, Sarah Umetsu, Adam Olshen, Ritu Roy, Ashley Kiemen, Man-Tzu Wang, Eric Collisson
• Analysis of DNA methylation at birth and in childhood reveals changes associated with season of birth and latitude.
  Clinical epigenetics 2023 Kadalayil L, Alam MZ, White CH, Ghantous A, Walton E, Gruzieva O, Merid SK, Kumar A, Roy RP, Solomon O, Huen K, Eskenazi B, Rzehak P, Grote V, Langhendries JP, Verduci E, Ferre N, Gruszfeld D, Gao L, …
• Venetoclax and dinaciclib elicit synergistic preclinical efficacy against hypodiploid acute lymphoblastic leukemia.
  Haematologica 2023 Pariury H, Fandel J, Bachl S, Ang KK, Markossian S, Wilson CG, Braun BS, Popescu B, Wohlfeil M, Beckman K, Xirenayi S, Roy RP, Olshen AB, Smith C, Arkin MR, Loh ML, Diaz-Flores E
• Prediction of morning fatigue severity in outpatients receiving chemotherapy: less may still be more.
  Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 2023 Kober KM, Roy R, Conley Y, Dhruva A, Hammer MJ, Levine J, Olshen A, Miaskowski C
• Torch-eCpG: A fast and scalable eQTM mapper for thousands of molecular phenotypes with graphical processing units.
  bioRxiv : the preprint server for biology 2023 Kober KM, Berger L, Roy R, Olshen A
• Therapeutic implications of transcriptomics in head and neck cancer patient-derived xenografts.
  PloS one 2023 Lee RH, Roy R, Li H, Hechmer A, Zhu TR, Izgutdina A, Olshen AB, Johnson DE, Grandis JR
• A Transcriptional Classifier Identifies Pediatric T-Cell Acute Lymphoblastic Leukemias at High Risk for End of Induction Minimal Residual Disease.
  Blood 2022 Lauren K. Meyer, Ritu P. Roy, Petri Pölönen, Abdelrahman Elsayed, Benjamin J. Huang, Shunsuke Kimura, Cristina Delgado-Martin, Tiffaney L. Vincent, Theresa Ryan, Brent L. Wood, Zhiguo Chen, Yu Liu, …
• Multiomic Single-Cell Sequencing of Mixed Phenotypic Acute Leukemia (MPAL) Reveals Complex Immunophenotypic, Transcriptional, and Genetic Heterogeneity.
  Blood 2022 Cheryl Peretz, Vanessa E. Kennedy, Anushka Walia, Cyrille Delley, Andrew Koh, Elaine Tran, Iain Clark, Corey Hayford, Yi Xue, Chris D'Amato, Kristina Fontanez, Ritu P. Roy, Adam Olshen, Aaron C. Logan…
• 049 A TARGETED GENE EXPRESSION CLASSIFIER IDENTIFIES PEDIATRIC T-ALL PATIENTS AT HIGH RISK FOR END INDUCTION MINIMAL RESIDUAL DISEASE POSITIVITY.
  Leukemia Research 2022 L. Meyer, Ritu P. Roy, B. Huang, S. Kimura, Petri Polonen, C. Delgado-Martin, T. Vincent, T. Ryan, B. Wood, Y. Liu, J. Zhang, C. Mullighan, T. Horton, M. Loh, M. Devidas, E. Raetz, R. Hayashi, S. …
• Caveolin-1 and Sox-2 are predictive biomarkers of cetuximab response in head and neck cancer.
  JCI insight 2021 Bouhaddou M, Lee RH, Li H, Bhola NE, O'Keefe RA, Naser M, Zhu TR, Nwachuku K, Duvvuri U, Olshen AB, Roy R, Hechmer A, Bolen J, Keysar SB, Jimeno A, Mills GB, Vandenberg S, Swaney DL, Johnson DE, …
• Targeted gene expression classifier identifies pediatric T-cell acute lymphoblastic leukemia (T-ALL) patients at high risk for end induction minimal residual disease positivity.
  Journal of Clinical Oncology 2021 Lauren K. Meyer, Ritu Roy, Benjamin J. Huang, Cristina Delgado-Martin, Tiffaney L. Vincent, Brent L. Wood, Yu Liu, Jinghui Zhang, Charles Grenfell Mullighan, Terzah M. Horton, Mignon L. Loh, Meenakshi…
• Prediction of evening fatigue severity in outpatients receiving chemotherapy: less may be more.
  Fatigue : biomedicine, health & behavior 2021 Kober KM, Roy R, Dhruva A, Conley YP, Chan RJ, Cooper B, Olshen A, Miaskowski C
• Human pediatric B-cell acute lymphoblastic leukemias can be classified as B-1 or B-2-like based on a minimal transcriptional signature.
  Experimental hematology 2020 Fitch B, Roy R, Geng H, Montecino-Rodriguez E, Bengtsson H, Gaillard C, Hiam K, Casero D, Olshen AB, Dorshkind K, Kogan SC
• Glucocorticoids paradoxically facilitate steroid resistance in T cell acute lymphoblastic leukemias and thymocytes.
  The Journal of clinical investigation 2020 Meyer LK, Huang BJ, Delgado-Martin C, Roy RP, Hechmer A, Wandler AM, Vincent TL, Fortina P, Olshen AB, Wood BL, Horton TM, Shannon KM, Teachey DT, Hermiston ML
• Next-Generation Sequencing of Retinoblastoma Identifies Pathogenic Alterations beyond RB1 Inactivation That Correlate with Aggressive Histopathologic Features.
  Ophthalmology 2019 Afshar AR, Pekmezci M, Bloomer MM, Cadenas NJ, Stevers M, Banerjee A, Roy R, Olshen AB, Van Ziffle J, Onodera C, Devine WP, Grenert JP, Bastian BC, Solomon DA, Damato BE
• The Genome-Wide Impact of Trisomy 21 on DNA Methylation and Its Implications for Hematologic Malignancies.
  Blood 2019 Joseph L. Wiemels, Ivo S Muskens, Shaobo Li, Priyatama Pandey, Ritu Roy, Helen M Hansen, Kimberly D Siegmund, Beth A Mueller, Xiaomei Ma, Catherine Metayer, Adam J de Smith
• Gene expression signature associated with in vitro dexamethasone resistance and post-induction minimal residual disease in pediatric T-cell acute lymphoblastic leukemia.
  Journal of Clinical Oncology 2019 Lauren K. Meyer, Cristina Delgado-Martin, Ritu Roy, Benjamin J. Huang, Tiffaney Vincent, Adam Olshen, Brent L. Wood, Yu Liu, Jinghui Zhang, Charles Grenfell Mullighan, Terzah M. Horton, Mignon L. Loh,…
• Next-Generation Sequencing of Uveal Melanoma for Detection of Genetic Alterations Predicting Metastasis.
  Translational vision science & technology 2019 Afshar AR, Damato BE, Stewart JM, Zablotska LB, Roy R, Olshen AB, Joseph NM, Bastian BC
• Autocrine TGFβ Is a Survival Factor for Monocytes and Drives Immunosuppressive Lineage Commitment.
  Cancer immunology research 2018 Gonzalez-Junca A, Driscoll KE, Pellicciotta I, Du S, Lo CH, Roy R, Parry R, Tenvooren I, Marquez DM, Spitzer MH, Barcellos-Hoff MH
• Glucocorticoids Paradoxically Induce Intrinsic Steroid Resistance through a STAT5-Mediated Survival Mechanism in T-Cell Acute Lymphoblastic Leukemia.
  Blood 2018 Lauren K. Meyer, Benjamin Huang, Ritu Roy, Aaron Hechmer, Anica Wandler, Cristina Delgado-Martin, Adam B. Olshen, Terzah M. Horton, David T Teachey, Kevin M. Shannon, Michelle L. Hermiston
• Genomic and expression profiling reveal molecular heterogeneity of disseminated tumor cells in bone marrow of early breast cancer.
  NPJ breast cancer 2018 Magbanua MJM, Rugo HS, Hauranieh L, Roy R, Scott JH, Lee JC, Hsiao F, Sosa EV, Van't Veer L, Esserman LJ, Park JW
• Abstract 5578: Genomic and expression profiling reveals molecular heterogeneity of disseminated tumor cells in early breast cancer.
  Clinical Research (Excluding Clinical Trials) 2018 Mark Jesus M. Magbanua, Hope Rugo, Louai Hauranieh, Ritu Roy, Janet Scott, Jen Chieh Lee, Feng Hsiao, Eduardo Sosa, Denise Wolf, Laura van't Veer, Laura Esserman, John Park
• Replication confers β cell immaturity.
  Nature communications 2018 Puri S, Roy N, Russ HA, Leonhardt L, French EK, Roy R, Bengtsson H, Scott DK, Stewart AF, Hebrok M
• Cohort Profile: Pregnancy And Childhood Epigenetics (PACE) Consortium.
  International journal of epidemiology 2018 Felix JF, Joubert BR, Baccarelli AA, Sharp GC, Almqvist C, Annesi-Maesano I, Arshad H, Baïz N, Bakermans-Kranenburg MJ, Bakulski KM, Binder EB, Bouchard L, Breton CV, Brunekreef B, Brunst KJ, Burchard…
• Expanded Genomic Profiling of Circulating Tumor Cells in Metastatic Breast Cancer Patients to Assess Biomarker Status and Biology Over Time (CALGB 40502 and CALGB 40503, Alliance).
  Clinical cancer research : an official journal of the American Association for Cancer Research 2018 Magbanua MJM, Rugo HS, Wolf DM, Hauranieh L, Roy R, Pendyala P, Sosa EV, Scott JH, Lee JS, Pitcher B, Hyslop T, Barry WT, Isakoff SJ, Dickler M, Van't Veer L, Park JW
• Characterization of Metabolic, Diffusion, and Perfusion Properties in GBM: Contrast-Enhancing versus Non-Enhancing Tumor.
  Translational oncology 2017 Autry A, Phillips JJ, Maleschlijski S, Roy R, Molinaro AM, Chang SM, Cha S, Lupo JM, Nelson SJ
• Association of early changes in 1H MRSI parameters with survival for patients with newly diagnosed glioblastoma receiving a multimodality treatment regimen.
  Neuro-oncology 2017 Nelson SJ, Kadambi AK, Park I, Li Y, Crane J, Olson M, Molinaro A, Roy R, Butowski N, Cha S, Chang S
• Abstract P1-01-04: Comprehensive genomic characterization of circulating tumor cells (CTCs) in metastatic breast cancer (MBC) sheds light on the biology of blood-borne metastasis.
  Poster Session Abstracts 2017 MJ Magbanua, L Hauranieh, R Roy, D Wolf, S Benz, C Vaske, P Pendyala, E Sosa, J Scott, JS Lee, A Ordonez, B Ho, T Solanki, L VantVeer, H Rugo, J Park
• Correlates of Prenatal and Early-Life Tobacco Smoke Exposure and Frequency of Common Gene Deletions in Childhood Acute Lymphoblastic Leukemia.
  Cancer research 2017 de Smith AJ, Kaur M, Gonseth S, Endicott A, Selvin S, Zhang L, Roy R, Shao X, Hansen HM, Kang AY, Walsh KM, Dahl GV, McKean-Cowdin R, Metayer C, Wiemels JL
• Immunomethylomic approach to explore the blood neutrophil lymphocyte ratio (NLR) in glioma survival.
  Clinical epigenetics 2017 Wiencke JK, Koestler DC, Salas LA, Wiemels JL, Roy RP, Hansen HM, Rice T, McCoy LS, Bracci PM, Molinaro AM, Kelsey KT, Wrensch MR, Christensen BC
• Genetic Subtypes of Human Pediatric ALLs Show Gene Expression Differences That Parallel Those Observed in Mouse B1 and B2 Progenitors, Suggesting Divergent Developmental Origins.
  Blood 2016 Scott C. Kogan, Huimin Geng, Ritu Roy, Encarnacion Montecino-Rodriguez, Coline M Gaillard, Kamir Hiam, Henrik Bengtsson, David Casero, Adam B Olshen, Kenneth Dorshkind
• GENT-13. IMMUNOMETHYLOMIC ASSAY OF BLOOD NEUTROPHIL LYMPHOCYTE RATIO (NLR) IN GLIOMA SURVIVAL.
  Neuro-Oncology 2016 John Wiencke, Devin Koestler, Annette Molinaro, Joseph Wiemels, Ritu Roy, Helen Hansen, Terri Rice, Paige Bracci, Lucie McCoy, Karl Kelsey, Margaret Wrensch, Brock Christensen
• Serial analysis of 3D H-1 MRSI for patients with newly diagnosed GBM treated with combination therapy that includes bevacizumab.
  Journal of neuro-oncology 2016 Nelson SJ, Li Y, Lupo JM, Olson M, Crane JC, Molinaro A, Roy R, Clarke J, Butowski N, Prados M, Cha S, Chang SM
• Genetic contribution to variation in DNA methylation at maternal smoking-sensitive loci in exposed neonates.
  Epigenetics 2016 Gonseth S, de Smith AJ, Roy R, Zhou M, Lee ST, Shao X, Ohja J, Wrensch MR, Walsh KM, Metayer C, Wiemels JL
• An improved CTC isolation scheme for pairing with downstream genomics: Demonstrating clinical utility in metastatic prostate, lung and pancreatic cancer.
  Cancer letters 2016 Premasekharan G, Gilbert E, Okimoto RA, Hamirani A, Lindquist KJ, Ngo VT, Roy R, Hough J, Edwards M, Paz R, Foye A, Sood R, Copren KA, Gubens M, Small EJ, Bivona TG, Collisson EA, Friedlander TW, …
• Genomic profiling to distinguish poorly differentiated neuroendocrine carcinomas arising in different sites.
  Journal of Clinical Oncology 2016 Emily K. Bergsland, Ritu Roy, Phil Stephens, Jeffrey S. Ross, Mark Bailey, Adam Olshen
• Association of Diffusion and Anatomic Imaging Parameters with Survival for Patients with Newly Diagnosed Glioblastoma Participating in Two Different Clinical Trials.
  Translational oncology 2015 Wen Q, Jalilian L, Lupo JM, Li Y, Roy R, Molinaro AM, Chang SM, Prados M, Butowski N, Clarke J, Nelson SJ
• Associations between circulating carotenoids, genomic instability and the risk of high-grade prostate cancer.
  The Prostate 2015 Nordström T, Van Blarigan EL, Ngo V, Roy R, Weinberg V, Song X, Simko J, Carroll PR, Chan JM, Paris PL
• Exome sequencing of desmoplastic melanoma identifies recurrent NFKBIE promoter mutations and diverse activating mutations in the MAPK pathway.
  Nature genetics 2015 Shain AH, Garrido M, Botton T, Talevich E, Yeh I, Sanborn JZ, Chung J, Wang NJ, Kakavand H, Mann GJ, Thompson JF, Wiesner T, Roy R, Olshen AB, Gagnon A, Gray JW, Huh N, Hur JS, Busam KJ, Scolyer RA, …
• Abstract 1591: Comprehensive molecular profiling of circulating tumor cells from metastatic breast cancer patients.
  Clinical Research (Excluding Clinical Trials) 2015 Mark Jesus Mendoza Magbanua, Louai Hauranieh, Ritu Roy, Praveen Pendyala, Eduardo Sosa, Janet Scott, Hope Rugo, John Park
• Abstract 2763: Maternal folate intake at periconception and genome-wide DNA methylation modifications at birth in children.
  Epidemiology 2015 Semira Gonseth, Ritu Roy, E. Andres Houseman, Adam de Smith, Mi Zhou, Seung-Tae Lee, Sébastien Nusslé, Amanda W. Singer, Margaret R. Wrensch, Catherine Metayer, Joseph L. Wiemels
• Abstract 2968: Exome sequencing of desmoplastic melanoma reveals recurrent NFKBIE promoter mutations and diverse MAPK/PI3K pathway activating mutations.
  Molecular and Cellular Biology 2015 Alan H. Shain, Maria Garrido, Thomas Botton, Eric Talevich, Iweh Yeh, Zack Sanborn, Jongsuk Chung, Nicholas Wang, Hojabr Kakavand, Graham Mann, John Thompson, Thomas Wiesner, Ritu Roy, Adam Olshen, …
• Abstract 831: In utero polycyclic aromatic hydrocarbons exposure and genome-wide DNA methylation modifications at birth in children who develop acute lymphoblastic leukemia.
  Epidemiology 2015 Semira Gonseth, Todd P. Whitehead, Ritu Roy, E. Andres Houseman, Adam J. de Smith, Mi Zhou, Seung-Tae Lee, Margaret R. Wrensch, Stephen M. Rappaport, Catherine Metayer, Joseph L. Wiemels
• Transcription and methylation analyses of preleukemic promyelocytes indicate a dual role for PML/RARA in leukemia initiation.
  Haematologica 2015 Gaillard C, Tokuyasu TA, Rosen G, Sotzen J, Vitaliano-Prunier A, Roy R, Passegué E, de Thé H, Figueroa ME, Kogan SC
• Epigenetic remodeling in B-cell acute lymphoblastic leukemia occurs in two tracks and employs embryonic stem cell-like signatures.
  Nucleic acids research 2015 Lee ST, Muench MO, Fomin ME, Xiao J, Zhou M, de Smith A, Martín-Subero JI, Heath S, Houseman EA, Roy R, Wrensch M, Wiencke J, Metayer C, Wiemels JL
• Periconceptional folate consumption is associated with neonatal DNA methylation modifications in neural crest regulatory and cancer development genes.
  Epigenetics 2015 Gonseth S, Roy R, Houseman EA, de Smith AJ, Zhou M, Lee ST, Nusslé S, Singer AW, Wrensch MR, Metayer C, Wiemels JL
• Two-Track Epigenetic Remodeling and Backtracking to Embryonic Stem Cell Bivalency in B-Cell Acute Lymphoblastic Leukemias.
  Blood 2014 Seung-Tae Lee, Marcus O. Muench, Marina Fomin, Jianqiao Xiao, Mi Zhou, Adam J. de Smith, José Martín-Subero, Simon Heath, E. Andres Houseman, Ritu Roy, Margaret R. Wrensch, John K. Wiencke, Catherine …
• Genetic variants of Adam17 differentially regulate TGFβ signaling to modify vascular pathology in mice and humans.
  Proceedings of the National Academy of Sciences of the United States of America 2014 Kawasaki K, Freimuth J, Meyer DS, Lee MM, Tochimoto-Okamoto A, Benzinou M, Clermont FF, Wu G, Roy R, Letteboer TG, Ploos van Amstel JK, Giraud S, Dupuis-Girod S, Lesca G, Westermann CJ, Coffey RJ, …
• Genome-wide copy number analysis of cerebrospinal fluid tumor cells and their corresponding archival primary tumors.
  Genomics data 2014 Magbanua MJ, Roy R, Sosa EV, Hauranieh L, Kablanian A, Eisenbud LE, Ryazantsev A, Au A, Scott JH, Melisko M, Park JW
• PTPRG inhibition by DNA methylation and cooperation with RAS gene activation in childhood acute lymphoblastic leukemia.
  International journal of cancer 2014 Xiao J, Lee ST, Xiao Y, Ma X, Houseman EA, Hsu LI, Roy R, Wrensch M, de Smith AJ, Chokkalingam A, Buffler P, Wiencke JK, Wiemels JL
• Molecular profiling of tumor cells in cerebrospinal fluid and matched primary tumors from metastatic breast cancer patients with leptomeningeal carcinomatosis.
  Cancer research 2013 Magbanua MJ, Melisko M, Roy R, Sosa EV, Hauranieh L, Kablanian A, Eisenbud LE, Ryazantsev A, Au A, Scott JH, Park JW
• Detection and genomic interrogation of invasive circulating tumor cells (iCTCs) derived from men with metastatic castration resistant prostate cancer (mCRPC).
  Journal of Clinical Oncology 2013 Terence W. Friedlander, Vivian K. Weinberg, Ritu Roy, Vy Ngo, Huang Dong, Shaun Doty, Qiang Zhao, Gayatri Premasekharan, Elizabeth Gilbert, Charles J. Ryan, Wen-Tien Chen, Pamela Paris
• Genomic profiling of isolated circulating tumor cells from metastatic breast cancer patients.
  Cancer research 2012 Magbanua MJ, Sosa EV, Roy R, Eisenbud LE, Scott JH, Olshen A, Pinkel D, Rugo HS, Park JW
• Diversity of antigen-specific responses induced in vivo with CTLA-4 blockade in prostate cancer patients.
  Journal of immunology (Baltimore, Md. : 1950) 2012 Kwek SS, Dao V, Roy R, Hou Y, Alajajian D, Simko JP, Small EJ, Fong L
• Regulators of skeletal development: a cluster analysis of 206 bone tumors reveals diagnostically useful markers.
  Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2012 Horvai AE, Roy R, Borys D, O'Donnell RJ
• Abstract 5079: A genomic copy number biomarker to identify oral cancer patients at low risk for metastasis.
  Molecular and Cellular Biology 2012 Aditi Bhattacharya, Antoine M. Snijders, Ritu Roy, Gregory Hamilton, Jesse Paquette, Taku Tokuyasu, Henrik Bengtsson, Richard CK Jordan, Adam Olshen, Daniel Pinkel, Brian L. Schmidt, Donna G. …
• Mouse and human strategies identify PTPN14 as a modifier of angiogenesis and hereditary haemorrhagic telangiectasia.
  Nature communications 2012 Benzinou M, Clermont FF, Letteboer TG, Kim JH, Espejel S, Harradine KA, Arbelaez J, Luu MT, Roy R, Quigley D, Higgins MN, Zaid M, Aouizerat BE, van Amstel JK, Giraud S, Dupuis-Girod S, Lesca G, …
• Erratum: Mouse and human strategies identify PTPN14 as a modifier of angiogenesis and hereditary haemorrhagic telangiectasia.
  Nature Communications 2012 Michael Benzinou, Frederic F. Clermont, Tom G W. Letteboer, Jai-hyun Kim, Silvia Espejel, Kelly A. Harradine, Juan Arbelaez, Minh Thu Luu, Ritu Roy, David Quigley, Mamie Nakayama Higgins, Musa Zaid, …
• P1-06-09: Patient-Specific Integrative Pathway Analysis Using PARADIGM Identifies Key Activities in I-SPY 1 Breast Cancer Patients (CALGB 150007/150012; ACRIN 6657).
  Poster Session Abstracts 2011 DM Wolf, C Yau, S Benz, C Vaske, J Stuart, R Roy, A Olshen, A Boudreau, D Haussler, J Gray, P Spellman, S Davis, N Hylton, L Van Veer, L Esserman
• Common structural and epigenetic changes in the genome of castration-resistant prostate cancer.
  Cancer research 2011 Friedlander TW, Roy R, Tomlins SA, Ngo VT, Kobayashi Y, Azameera A, Rubin MA, Pienta KJ, Chinnaiyan A, Ittmann MM, Ryan CJ, Paris PL
• Abstract A69: Subtype-specific targeting of RAS signal transduction in pancreatic ductal adenocarcinoma.
  Cellular Responses to Therapy 2011 Olga K. Mirzoeva, Eric A. Collisson, Peter M. Schaefer, Ritu Roy, W. Michael Korn
• Two distinct routes to oral cancer differing in genome instability and risk for cervical node metastasis.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2011 Bhattacharya A, Roy R, Snijders AM, Hamilton G, Paquette J, Tokuyasu T, Bengtsson H, Jordan RC, Olshen AB, Pinkel D, Schmidt BL, Albertson DG
• Genome-wide copy number analysis of circulating tumor cells from patients (pts) with metastatic breast cancer (MBC).
  Journal of Clinical Oncology 2011 M. J. M. Magbanua, E. Sosa, R. Roy, L. Eisenbud, J. Scott, A. Olshen, D. Pinkel, H. S. Rugo, J. W. Park
• Gene expression and biological pathways in tissue of men with prostate cancer in a randomized clinical trial of lycopene and fish oil supplementation.
  PloS one 2011 Magbanua MJ, Roy R, Sosa EV, Weinberg V, Federman S, Mattie MD, Hughes-Fulford M, Simko J, Shinohara K, Haqq CM, Carroll PR, Chan JM
• Genomic alterations and phenotype of large compared to small high-grade ductal carcinoma in situ.
  Human pathology 2011 Hwang ES, Lal A, Chen YY, DeVries S, Swain R, Anderson J, Roy R, Waldman FM
• Identification of gene copy number and whole-genome methylation changes associated with lethal metastatic castration-resistant prostate cancer (CRPC).
  Journal of Clinical Oncology 2011 T. W. Friedlander, R. Roy, S. A. Tomlins, Y. Kobayashi, M. A. Rubin, K. J. Pienta, A. Chinnaiyan, E. J. Small, C. J. Ryan, P. Paris
• Genetic and morphologic features for melanoma classification.
  Pigment cell & melanoma research 2010 Broekaert SM, Roy R, Okamoto I, van den Oord J, Bauer J, Garbe C, Barnhill RL, Busam KJ, Cochran AJ, Cook MG, Elder DE, McCarthy SW, Mihm MC, Schadendorf D, Scolyer RA, Spatz A, Bastian BC
• Identification of novel prostate cancer-associated antigens through antibody profiling of prostate cancer patients treated with CTLA-4 blockade.
  Journal of Clinical Oncology 2010 L. Fong, S. Kwek, V. Dao, R. Roy, Y. Hou, J. Simko, E. J. Small
• Abstract 2137: Association of copy number aberrations with oral cancer metastasis and progression of pre-malignant oral lesions.
  Cellular and Molecular Biology 2010 Aditi Bhattachayra, Antoine M. Snijders, Ritu Roy, Taku Tokuyasu, Richard C. K. Jordan, Adam Olshen, Daniel Pinkel, Brian L. Schmidt, Donna G. Albertson
• A group of genome-based biomarkers that add to a Kattan nomogram for predicting progression in men with high-risk prostate cancer.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2009 Paris PL, Weinberg V, Albo G, Roy R, Burke C, Simko J, Carroll P, Collins C
• Loss of Blm enhances basal cell carcinoma and rhabdomyosarcoma tumorigenesis in Ptch1+/- mice.
  Carcinogenesis 2009 Davari P, Hebert JL, Albertson DG, Huey B, Roy R, Mancianti ML, Horvai AE, McDaniel LD, Schultz RA, Epstein EH
• Genetic and phenotypic characteristics of pleomorphic lobular carcinoma in situ of the breast.
  The American journal of surgical pathology 2009 Chen YY, Hwang ES, Roy R, DeVries S, Anderson J, Wa C, Fitzgibbons PL, Jacobs TW, MacGrogan G, Peterse H, Vincent-Salomon A, Tokuyasu T, Schnitt SJ, Waldman FM
• Similarity in genetic alterations between paired well-differentiated and dedifferentiated components of dedifferentiated liposarcoma.
  Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2009 Horvai AE, DeVries S, Roy R, O'Donnell RJ, Waldman F
• Integration of genomic analysis and in vivo transfection to identify sprouty 2 as a candidate tumor suppressor in liver cancer.
  Hepatology (Baltimore, Md.) 2008 Lee SA, Ho C, Roy R, Kosinski C, Patil MA, Tward AD, Fridlyand J, Chen X
• Evaluation of whole genome amplification protocols for array and oligonucleotide CGH.
  Diagnostic molecular pathology : the American journal of surgical pathology, part B 2007 Hittelman A, Sridharan S, Roy R, Fridlyand J, Loda M, Collins C, Paris PL