Jacque Duncan, MD
Professor
Ophthalmology
School of Medicine

My clinical specialty is diagnosing and caring for patients with these diseases, using modalities from fluorescein angiography, to optical coherence tomography (OCT), to electroretinography (ERG).

In both RP and AMD, loss of vision is a result of photoreceptor cell degeneration and death. Treatments that can prevent photoreceptor degeneration in experimental models of retinal degenerations may have utility in preventing degeneration in both RP and AMD. I am interested in investigating novel treatments to preserve retinal function in patients with RP, cone rod dystrophy, Stargardt disease, Best disease and AMD.

Patients with rod specific defects undergo degeneration not only of rods, but also of cone photoreceptors. Because cones are responsible for fine visual acuity and color perception, their degeneration is particularly disabling for patients. I am interested in studying the relationship between cone photoreceptor survival and rod-specific gene defects in hereditary retinal degenerations, with the goal of preserving visual function mediated by both rods and cones.

A major challenge in the study of retinal degenerations lies in the fact that the cells affected by these diseases, the photoreceptors and retinal pigment epithelial (RPE) cells, are not visible in the eyes of living people. My collaborator Dr. Austin Roorda at the UC Berkeley School of Optometry has developed a novel device, the adaptive optics scanning laser ophthalmoscope (AOSLO), with the ability to image individual cone photoreceptors in the central retina of living eyes. We have studied cones in patients with RP, cone-rod dystrophy and other types of retinal degeneration to better understand why vision is lost in these diseases. See Dr. Roorda’s laboratory webpage for additional details about this research.

The UCSF Retinal Degenerations Clinic participated in 3 multi-center clinical trials for patients with inherited retinal degenerations. Two Phase II/III clinical trials evaluated the effect that a growth factor called ciliary neurotrophic factor (CNTF) has on retinal function in patients with early and late stages of RP. A Phase I study evaluated the safety and efficacy of a new generation epiretinal prosthetic device to stimulate visual perception in patients with end-stage RP. These clinical trials are among the first to study possible treatments for patients with these blinding diseases.

• Longitudinal Assessment of Cone Structure, Choriocapillaris, and Retinal Sensitivity in Choroideremia.
  Investigative ophthalmology & visual science 2025 Shen LL, Zhang Y, Wong J, Foote KG, Porco TC, Wang RK, Roorda A, Duncan JL
• Ciliary Neurotrophic Factor - A Promising New Therapy for Macular Telangiectasia Type 2.
  NEJM evidence 2025 Duncan JL
• Repeated Low-Level Red Light-More Than Meets the Eye?
  JAMA ophthalmology 2025 Duncan JL
• Natural History of Microperimetry and Optical Coherence Tomography in USH2A-Retinopathy: A Structure-Function Association Study.
  American journal of ophthalmology 2025 Vincent A, Liang W, Maguire MG, Duncan JL, Ayala AR, Bernstein PS, Carroll J, Cheetham JK, Durham TA, Farsiu S, Hoyng CB, Huckfeldt RM, Jaffe GJ, Loo J, Pennesi ME, Sahel JA, Singh MS, Zemborain ZZ, …
• Functional Vision Assessment Over 4 Years in USH2A Using the Veteran Affairs Low-Vision Visual Functioning Questionnaire.
  Investigative ophthalmology & visual science 2025 Parekh B, Peck-Dimit N, Duncan JL, Samarakoon L, Abalem MF, Andrews CA, Audo I, Ayala AR, Bradley C, Cheetham JK, Dagnelie G, Durham TA, Huckfeldt RM, Lacy GD, Malbin B, Michaelides M, Musch DC, …
• High Resolution Imaging and Fixation Analysis of Eccentric Preferred Retinal Loci in Macular Diseases.
  Investigative ophthalmology & visual science 2025 Kolawole OU, Bensinger E, Wong J, Rinella N, Foote KG, Zhou H, Wang RK, Duncan JL, Roorda A
• Variants in CFAP410 cause a range of retinal and skeletal phenotypes.
  NPJ genomic medicine 2025 Schmidt RE, Pohodich AE, Birch D, Jones K, Lam BL, Jung EH, Jain N, Georgiou M, Mahroo OA, Webster AR, Michaelides M, Bakall B, Iannaccone A, Vincent A, Parameswarappa DC, Heon E, Scholl HPN, …
• Characterization of Visual Field Loss Over 4 Years in the Rate of Progression in USH2A-Related Retinal Degeneration (RUSH2A) Study.
  American journal of ophthalmology 2025 Duncan JL, Maguire MG, McDaniel LS, Doucet NR, Audo I, Ayala AR, Cheetham JK, Cheng P, Durham TA, Huckfeldt RM, Hufnagel RB, Jayasundera KT, Khan N, Malbin B, Maldonado RS, Michaelides M, Pennesi ME, …
• Assessing structure - Function relationships in non-neovascular age-related macular degeneration.
  Experimental eye research 2025 Chew EY, Cukras C, Duncan JL, Dysli C, He Y, Henry E, Holz F, Moult E, Owsley C, Roorda A, Sarraf D, Schwartz R, Spaide R, Taylor L, Teussink M, Zhang Y, Staurenghi G
• Corrigendum to "Baseline Visual Field Findings in the RUSH2A Study: Associated Factors and Correlation With Other Measures of Disease Severity" [Am J Ophthalmol 2020;219:87-100].
  American journal of ophthalmology 2025 Duncan JL, Liang W, Maguire MG, Audo I, Ayala AR, Birch DG, Carroll J, Cheetham JK, Esposti SD, Durham TA, Erker L, Farsiu S, Ferris FL, Heon E, Hufnagel RB, Iannaccone A, Jaffe GJ, Kay CN, …
• Long-term natural history of ellipsoid zone width in USH2A-retinopathy.
  The British journal of ophthalmology 2025 Heyang M, Warren JL, Ocieczek P, Duncan JL, Moosajee M, Del Priore LV, Shen LL
• Outer retinal reflectivity and visual function loss after anatomically successful macula-off rhegmatogenous retinal detachment repair.
  American journal of ophthalmology case reports 2025 Kolli A, Wong J, Duret S, Stewart JM, Connor TB, Roorda A, Carroll J, Duncan JL
• Characterizing the Genetic Basis for Inherited Retinal Disease: Lessons Learned From the Foundation Fighting Blindness Clinical Consortium's Gene Poll.
  Investigative ophthalmology & visual science 2025 Branham K, Samarakoon L, Audo I, Ayala AR, Cheetham JK, Daiger SP, Dhooge P, Duncan JL, Durham TA, Fahim AT, Huckfeldt RM, Hufnagel RB, Kohl S, Maldonado RS, Melia M, Michaelides M, Pennesi ME, Sahel …
• De novo and inherited dominant variants in U4 and U6 snRNAs cause retinitis pigmentosa.
  medRxiv : the preprint server for health sciences 2025 Quinodoz M, Rodenburg K, Cvackova Z, Kaminska K, de Bruijn SE, Iglesias-Romero AB, Boonen EGM, Ullah M, Zomer N, Folcher M, Bijon J, Holtes LK, Tsang SH, Corradi Z, Freund KB, Shliaga S, Panneman DM, …
• Inherited Retinal Degenerations and Non-Neovascular Age-Related Macular Degeneration: Progress and Unmet Needs.
  Translational vision science & technology 2024 Duncan JL, Bowman A, Laster A, Gelfman C, Birch DG, Boye SE, Daiger SP, Del Priore L, Zack DJ, Handa JT, Foundation Fighting Blindness Scientific Advisory Board
• Retinal Disorders.
  Cold Spring Harbor perspectives in medicine 2024 Sahel JA, Banin E, Bennett J, Duncan JL, Roska B
• Novel BBS1 deletion and BBS9 nonsense pathogenic variant in Bardet-Biedl syndrome.
  Ophthalmic genetics 2024 Li JM, Tavares E, Duncan JL, Vincent A, Héon E
• Coding and non-coding variants in the ciliopathy gene CFAP410 cause early-onset non-syndromic retinal degeneration.
  NPJ genomic medicine 2024 Sangermano R, Gupta P, Price C, Han J, Navarro J, Condroyer C, Place EM, Antonio A, Mukai S, Zanlonghi X, Sahel JA, DiTroia S, O'Heir E, Duncan JL, Pierce EA, Zeitz C, Audo I, Huckfeldt RM, Bujakowska…
• Visual Acuity, Full-field Stimulus Thresholds, and Electroretinography for 4 Years in The Rate of Progression of USH2A-related Retinal Degeneration (RUSH2A) Study.
  Ophthalmology science 2024 Birch DG, Cheng P, Maguire MG, Duncan JL, Ayala AR, Cheetham JK, Doucet NR, Durham TA, Fahim AT, Ferris FL, Huckfeldt RM, Melia M, Michaelides M, Pennesi ME, Sahel JA, Stingl K, Vincent A, Weng CY
• Differences in COVID-19 Vaccination and Experiences among Patients with Hypertension in Colombia and Jamaica during the COVID-19 Pandemic.
  International journal of environmental research and public health 2024 Duncan JP, Geng S, Lindsay C, Ferguson TS, Mills KT, Lopez-Lopez JP, He H, Lanza P, Marshall AN, Williams MJ, Tonwe V, Reyes M, Campo A, Lopez-Jaramillo P, Tulloch-Reid MK
• Endpoints and Design for Clinical Trials in USH2A-Related Retinal Degeneration: Results and Recommendations From the RUSH2A Natural History Study.
  Translational vision science & technology 2024 Maguire MG, Birch DG, Duncan JL, Ayala AR, Ayton LN, Cheetham JK, Cheng P, Durham TA, Ferris FL, Hoyng CB, Huckfeldt RM, Jaffe GJ, Kay C, Lad EM, Leroy BP, Liang W, McDaniel LS, Melia M, Michaelides M…
• XOLARIS: A 24-Month, Prospective, Natural History Study of 201 Participants with Retinitis Pigmentosa GTPase Regulator-Associated X-Linked Retinitis Pigmentosa.
  Ophthalmology science 2024 MacLaren RE, Duncan JL, Fischer MD, Lam BL, Meunier I, Pennesi ME, Sankila EK, Gow JA, Li J, Tsang SF, XOLARIS Study Group
• Neuropathy target esterase activity defines phenotypes among PNPLA6 disorders.
  Brain : a journal of neurology 2024 Liu J, He Y, Lwin C, Han M, Guan B, Naik A, Bender C, Moore N, Huryn LA, Sergeev YV, Qian H, Zeng Y, Dong L, Liu P, Lei J, Haugen CJ, Prasov L, Shi R, Dollfus H, Aristodemou P, Laich Y, Németh AH, …
• Perimacular Atrophy Following Voretigene Neparvovec-Rzyl Treatment in the Setting of Previous Contralateral Eye Treatment With a Different Viral Vector.
  Translational vision science & technology 2024 Ku CA, Igelman AD, Huang SJ, Bailey ST, Lauer AK, Duncan JL, Weleber RG, Yang P, Pennesi ME
• Self-Reported Functional Vision in USH2A-Associated Retinal Degeneration as Measured by the Michigan Retinal Degeneration Questionnaire.
  Investigative ophthalmology & visual science 2024 Parekh B, Duncan JL, Samarakoon L, Melia M, Abalem MF, Andrews CA, Audo I, Ayala AR, Bradley C, Cheetham JK, Dagnelie G, Durham TA, Huckfeldt RM, Lacy GD, Malbin B, Michaelides M, Musch DC, Peck-Dimit…
• Disease modeling and pharmacological rescue of autosomal dominant retinitis pigmentosa associated with RHO copy number variation.
  eLife 2024 Kandoi S, Martinez C, Chen KX, Mehine M, Reddy LVK, Mansfield BC, Duncan JL, Lamba DA
• Disease modeling and pharmacological rescue of autosomal dominant retinitis pigmentosa associated with RHO copy number variation.
  eLife 2024 Sangeetha Kandoi, Cassandra Martinez, Kevin Xu Chen, Miika Mehine, L Vinod K Reddy, Brian C Mansfield, Jacque L Duncan, Deepak A Lamba
• Generative Artificial Intelligence Enhancements for Reducing Image-based Training Data Requirements.
  Ophthalmology science 2024 Chen D, Han Y, Duncan J, Jia L, Shan J
• Retinal End Points for ATXN7-Related Spinocerebellar Ataxia.
  JAMA ophthalmology 2024 Duncan JL
• Differences in COVID-19 Vaccination and Experiences among Patients with Hypertension in Colombia and Jamaica during the COVID-19 Pandemic.
  medRxiv : the preprint server for health sciences 2024 Duncan JP, Geng S, Lindsay C, Ferguson T, Mills K, Lopez-Lopez JP, He H, Lanza P, Williams M, Tutse-Tonwe V, Reyes M, Campo A, Marshall A, Lopez-Jaramillo P, Tulloch-Reid MK
• Coding and non-coding variants in the ciliopathy gene CFAP410 cause early-onset non-syndromic retinal degeneration.
  Research square 2024 Sangermano R, Gupta P, Price C, Han J, Navarro J, Condroyer C, Place EM, Antonio A, Mukai S, Zanlonghi X, Sahel JA, Duncan JL, Pierce EA, Zeitz C, Audo I, Huckfeldt RM, Bujakowska KM
• Functional Vision in Patients With Biallelic USH2A Variants.
  American journal of ophthalmology 2023 Heon E, Melia M, Bocchino LE, Samarakoon L, Duncan JL, Ayala AR, Audo I, Bradley C, Cheetham JK, Dagnelie G, Durham TA, Hoyng CB, Jain N, Jayasundera KT, Pennesi ME, Weng CY, Foundation Fighting …
• Disease modeling and pharmacological rescue of autosomal dominant Retinitis Pigmentosa associated with RHO copy number variation.
  medRxiv : the preprint server for health sciences 2023 Kandoi S, Martinez C, Chen KX, Reddy LVK, Mehine M, Mansfield BC, Duncan JL, Lamba DA
• Classification and Growth Rate of Chorioretinal Atrophy after Voretigene Neparvovec-Rzyl for RPE65-Mediated Retinal Degeneration.
  Ophthalmology. Retina 2023 Bommakanti N, Young BK, Sisk RA, Berrocal AM, Duncan JL, Bakall B, Mathias MT, Ahmed I, Chorfi S, Comander J, Nagiel A, Besirli CG
• Adaptive Optics Imaging of Inherited Retinal Disease.
  Cold Spring Harbor perspectives in medicine 2023 Duncan JL, Carroll J
• Enhanced S-Cone Syndrome: Elevated Cone Counts Confer Supernormal Visual Acuity in the S-Cone Pathway.
  Investigative ophthalmology & visual science 2023 Wang Y, Wong J, Duncan JL, Roorda A, Tuten WS
• Neuropathy target esterase activity predicts retinopathy among PNPLA6 disorders.
  bioRxiv : the preprint server for biology 2023 Liu J, He Y, Lwin C, Han M, Guan B, Naik A, Bender C, Moore N, Huryn LA, Sergeev Y, Qian H, Zeng Y, Dong L, Liu P, Lei J, Haugen CJ, Prasov L, Shi R, Dollfus H, Aristodemou P, Laich Y, Németh AH, …
• Change in Cone Structure Over 24 Months in USH2A-Related Retinal Degeneration.
  American journal of ophthalmology 2023 Duncan JL, Liang W, Maguire MG, Porco TC, Wong J, Audo I, Cava JA, Grieve K, Kalitzeos A, Kreis J, Michaelides M, Norberg N, Paques M, Carroll J, Foundation Fighting Blindness Consortium Investigator …
• Static Perimetry in the Rate of Progression in USH2A-related Retinal Degeneration (RUSH2A) Study: Assessment Through 2 Years.
  American journal of ophthalmology 2023 Duncan JL, Cheng P, Maguire MG, Ayala AA, Birch DG, Cheetham JK, Durham TA, Fahim AT, Hoyng CB, Ishikawa H, Michaelides M, Pennesi ME, Sahel JA, Stingl K, Weng CY, Foundation Fighting Blindness …
• Cone Structure and Function in RPGR- and USH2A-Associated Retinal Degeneration.
  American journal of ophthalmology 2023 Micevych PS, Wong J, Zhou H, Wang RK, Porco TC, Carroll J, Roorda A, Duncan JL
• Enhanced S-cone Syndrome, a Mini-review.
  Advances in experimental medicine and biology 2023 Wang Y, Wong J, Duncan JL, Roorda A, Tuten WS
• Retinopathy and optic atrophy in a case of COQ2-related primary coenzyme Q10 deficiency.
  Ophthalmic genetics 2022 Stallworth JY, Blair DR, Slavotinek A, Moore AT, Duncan JL, de Alba Campomanes AG
• Baseline Microperimetry and OCT in the RUSH2A Study: Structure-Function Association and Correlation With Disease Severity.
  American journal of ophthalmology 2022 Lad EM, Duncan JL, Liang W, Maguire MG, Ayala AR, Audo I, Birch DG, Carroll J, Cheetham JK, Durham TA, Fahim AT, Loo J, Deng Z, Mukherjee D, Heon E, Hufnagel RB, Guan B, Iannaccone A, Jaffe GJ, Kay CN…
• Multisystem Inflammatory Syndrome in Adults (MIS-A) After COVID-19 Infection and Recent Vaccination with Recombinant Adenoviral Vector Encoding the Spike Protein Antigen of SARS-CoV-2 (ChAdOx1 nCoV-19, Vaxzevria).
  Journal of intensive care medicine 2022 Ehikhametalor K, Deans-Minott J, Duncan JP
• VALIDATION OF A DEEP LEARNING-BASED ALGORITHM FOR SEGMENTATION OF THE ELLIPSOID ZONE ON OPTICAL COHERENCE TOMOGRAPHY IMAGES OF AN USH2A-RELATED RETINAL DEGENERATION CLINICAL TRIAL.
  Retina (Philadelphia, Pa.) 2022 Loo J, Jaffe GJ, Duncan JL, Birch DG, Farsiu S
• Chorioretinal Findings as the Initial Presentation of Chronic Granulomatous Disease.
  Ophthalmic surgery, lasers & imaging retina 2022 Chen TA, Rayess N, Afshar AR, Moshfeghi DM, Duncan JL, de Alba Campomanes AG
• Expanding the phenotype of TTLL5-associated retinal dystrophy: a case series.
  Orphanet journal of rare diseases 2022 Oh JK, Vargas Del Valle JG, Lima de Carvalho JR, Sun YJ, Levi SR, Ryu J, Yang J, Nagasaki T, Emanuelli A, Rasool N, Allikmets R, Sparrow JR, Izquierdo NJ, Duncan JL, Mahajan VB, Tsang SH
• Tissue-specific genotype-phenotype correlations among USH2A-related disorders in the RUSH2A study.
  Human mutation 2022 Hufnagel RB, Liang W, Duncan JL, Brewer CC, Audo I, Ayala AR, Branham K, Cheetham JK, Daiger SP, Durham TA, Guan B, Heon E, Hoyng CB, Iannaccone A, Kay CN, Michaelides M, Pennesi ME, Singh MS, Ullah E…
• The RUSH2A Study: Dark-Adapted Visual Fields in Patients With Retinal Degeneration Associated With Biallelic Variants in the USH2A Gene.
  Investigative ophthalmology & visual science 2022 Birch DG, Samarakoon L, Melia M, Duncan JL, Ayala AR, Audo I, Cheetham JK, Durham TA, Iannaccone A, Pennesi ME, Stingl K, Foundation Fighting Blindness Consortium Investigator Group
• Choriocapillaris Changes in Myopic Macular Degeneration.
  Translational vision science & technology 2022 Li J, Zhou H, Feinstein M, Wong J, Wang RK, Chan L, Dai Y, Porco T, Duncan JL, Schwartz DM
• Comparative Natural History of Visual Function From Patients With Biallelic Variants in BBS1 and BBS10.
  Investigative ophthalmology & visual science 2021 Grudzinska Pechhacker MK, Jacobson SG, Drack AV, Scipio MD, Strubbe I, Pfeifer W, Duncan JL, Dollfus H, Goetz N, Muller J, Vincent AL, Aleman TS, Tumber A, Van Cauwenbergh C, De Baere E, Bedoukian E, …
• Deciphering the genetic architecture and ethnographic distribution of IRD in three ethnic populations by whole genome sequence analysis.
  PLoS genetics 2021 Biswas P, Villanueva AL, Soto-Hermida A, Duncan JL, Matsui H, Borooah S, Kurmanov B, Richard G, Khan SY, Branham K, Huang B, Suk J, Bakall B, Goldberg JL, Gabriel L, Khan NW, Raghavendra PB, Zhou J, …
• Allele-specific gene editing to rescue dominant CRX-associated LCA7 phenotypes in a retinal organoid model.
  Stem cell reports 2021 Chirco KR, Chew S, Moore AT, Duncan JL, Lamba DA
• Retinal Degeneration Secondary to MERTK Mutations: Potential Candidate for Gene Therapy.
  International ophthalmology clinics 2021 Shen-Sampas JH, Duret S, Duncan JL
• Correlation Between Localized Choriocapillaris Perfusion and Macular Function in Eyes with Geographic Atrophy.
  American journal of ophthalmology 2021 Rinella NT, Zhou H, Wong J, Zhang Q, Nattagh K, Porco TC, Wang RK, Schwartz DM, Duncan JL
• Auditory and olfactory findings in patients with USH2A-related retinal degeneration-Findings at baseline from the rate of progression in USH2A-related retinal degeneration natural history study (RUSH2A).
  American journal of medical genetics. Part A 2021 Iannaccone A, Brewer CC, Cheng P, Duncan JL, Maguire MG, Audo I, Ayala AR, Bernstein PS, Bidelman GM, Cheetham JK, Doty RL, Durham TA, Hufnagel RB, Myers MH, Stingl K, Zein WM, Foundation Fighting …
• PRESUMED FOVEAL BACILLARY LAYER DETACHMENT IN A PATIENT WITH TOXOPLASMOSIS CHORIORETINITIS AND PACHYCHOROID DISEASE.
  Retinal cases & brief reports 2021 Mehta N, Chong J, Tsui E, Duncan JL, Curcio CA, Freund KB, Modi Y
• Macular Degeneration, Age Related.
  2021 Liron Naftali Ben Haim, Jacque L Duncan, Shiri Zayit-Soudry
• LEBER CONGENITAL AMAUROSIS DUE TO CEP290 MUTATIONS-SEVERE VISION IMPAIRMENT WITH A HIGH UNMET MEDICAL NEED: A Review.
  Retina (Philadelphia, Pa.) 2021 Leroy BP, Birch DG, Duncan JL, Lam BL, Koenekoop RK, Porto FBO, Russell SR, Girach A
• PHENOTYPIC HETEROGENEITY IN A FAMILY WITH X-LINKED FAMILIAL EXUDATIVE VITREORETINOPATHY WITH PREVENTION OF VISUAL LOSS IN AN AFFECTED MALE CHILD WITH LASER TREATMENT IN INFANCY.
  Retinal cases & brief reports 2021 Flores Pimentel MA, De la Huerta I, Duncan JL, Slavotinek AM, Moore AT, de Alba Campomanes AG
• Tackling the Challenges of Product Development Through a Collaborative Rare Disease Network: The Foundation Fighting Blindness Consortium.
  Translational vision science & technology 2021 Durham TA, Duncan JL, Ayala AR, Birch DG, Cheetham JK, Ferris FL, Hoyng CB, Pennesi ME, Sahel JA, Foundation Fighting Blindness Consortium Investigator Group
• SARS-CoV-2: an occupational hazard presenting challenges for low- and middle-income countries.
  International archives of occupational and environmental health 2021 Duncan JP, Figueroa JP
• Biometrics, Impact, and Significance of Basal Linear Deposit and Subretinal Drusenoid Deposit in Age-Related Macular Degeneration.
  Investigative ophthalmology & visual science 2021 Chen L, Messinger JD, Kar D, Duncan JL, Curcio CA
• The HIV epidemic in Jamaica: a need to strengthen the National HIV Program.
  Revista panamericana de salud publica = Pan American journal of public health 2020 Figueroa JP, Duncan JP, Bailey A, Skyers N
• Promises and pitfalls of evaluating photoreceptor-based retinal disease with adaptive optics scanning light ophthalmoscopy (AOSLO).
  Progress in retinal and eye research 2020 Wynne N, Carroll J, Duncan JL
• Response to: Comment on: Dark without pressure retinal changes in a paediatric age group.
  Eye (London, England) 2020 Pimentel MAF, Duncan JL, de Alba Campomanes AG, Moore AT
• The RUSH2A Study: Best-Corrected Visual Acuity, Full-Field Electroretinography Amplitudes, and Full-Field Stimulus Thresholds at Baseline.
  Translational vision science & technology 2020 Birch DG, Cheng P, Duncan JL, Ayala AR, Maguire MG, Audo I, Cheetham JK, Durham TA, Fahim AT, Ferris FL, Heon E, Huckfeldt RM, Iannaccone A, Khan NW, Lad EM, Michaelides M, Pennesi ME, Stingl K, …
• Biallelic variants in the RNA exosome gene EXOSC5 are associated with developmental delays, short stature, cerebellar hypoplasia and motor weakness.
  Human molecular genetics 2020 Slavotinek A, Misceo D, Htun S, Mathisen L, Frengen E, Foreman M, Hurtig JE, Enyenihi L, Sterrett MC, Leung SW, Schneidman-Duhovny D, Estrada-Veras J, Duncan JL, Haaxma CA, Kamsteeg EJ, Xia V, …
• ABUNDANCE AND MULTIMODAL VISIBILITY OF SOFT DRUSEN IN EARLY AGE-RELATED MACULAR DEGENERATION: A Clinicopathologic Correlation.
  Retina (Philadelphia, Pa.) 2020 Chen L, Messinger JD, Sloan KR, Wong J, Roorda A, Duncan JL, Curcio CA
• Dark without pressure retinal changes in a paediatric age group.
  Eye (London, England) 2020 Flores Pimentel MA, Duncan JL, de Alba Campomanes AG, Moore A
• Advancing Clinical Trials for Inherited Retinal Diseases: Recommendations from the Second Monaciano Symposium.
  Translational Vision Science & Technology 2020 Debra A. Thompson, Alessandro Iannaccone, Robin R. Ali, Vadim Y. Arshavsky, Isabelle Audo, James W. B. Bainbridge, Cagri G. Besirli, David G. Birch, Kari E. Branham, Artur V. Cideciyan, Steven P. …
• Advancing Clinical Trials for Inherited Retinal Diseases: Recommendations from the Second Monaciano Symposium.
  Translational vision science & technology 2020 Thompson DA, Iannaccone A, Ali RR, Arshavsky VY, Audo I, Bainbridge JWB, Besirli CG, Birch DG, Branham KE, Cideciyan AV, Daiger SP, Dalkara D, Duncan JL, Fahim AT, Flannery JG, Gattegna R, …
• OCT Angiography to Predict Geographic Atrophy Progression using Choriocapillaris Flow Void as a Biomarker.
  Translational vision science & technology 2020 Nattagh K, Zhou H, Rinella N, Zhang Q, Dai Y, Foote KG, Keiner C, Deiner M, Duncan JL, Porco TC, Wang RK, Schwartz DM
• Baseline Visual Field Findings in the RUSH2A Study: Associated Factors and Correlation With Other Measures of Disease Severity.
  American journal of ophthalmology 2020 Duncan JL, Liang W, Maguire MG, Audo I, Ayala AR, Birch DG, Carroll J, Cheetham JK, Esposti SD, Durham TA, Erker L, Farsiu S, Ferris FL, Heon E, Hufnagel RB, Iannaccone A, Jaffe GJ, Kay CN, …
• Comparing Cone Structure and Function in RHO- and RPGR-Associated Retinitis Pigmentosa.
  Investigative ophthalmology & visual science 2020 Foote KG, Wong JJ, Boehm AE, Bensinger E, Porco TC, Roorda A, Duncan JL
• Automated morphometric measurement of the retinal pigment epithelium complex and choriocapillaris using swept source OCT.
  Biomedical optics express 2020 Zhou H, Dai Y, Gregori G, Rosenfeld PR, Duncan JL, Schwartz DM, Wang RK
• Perspectives on Gene Therapy: Choroideremia Represents a Challenging Model for the Treatment of Other Inherited Retinal Degenerations.
  Translational Vision Science & Technology 2020 Ian M. MacDonald, Christopher Moen, Jacque L. Duncan, Stephen H. Tsang, Jasmina Cehajic-Kapetanovic, Tomas S. Aleman
• Perspectives on Gene Therapy: Choroideremia Represents a Challenging Model for the Treatment of Other Inherited Retinal Degenerations.
  Translational vision science & technology 2020 MacDonald IM, Moen C, Duncan JL, Tsang SH, Cehajic-Kapetanovic J, Aleman TS
• CHOROIDEREMIA: Retinal Degeneration With an Unmet Need.
  Retina (Philadelphia, Pa.) 2019 Pennesi ME, Birch DG, Duncan JL, Bennett J, Girach A
• Cone Structure Persists Beyond Margins of Short-Wavelength Autofluorescence in Choroideremia.
  Investigative ophthalmology & visual science 2019 Foote KG, Rinella N, Tang J, Bensaid N, Zhou H, Zhang Q, Wang RK, Porco TC, Roorda A, Duncan JL
• Gene Therapy for Choroideremia-Progress and Remaining Questions.
  JAMA ophthalmology 2019 Duncan JL
• Quantifying Choriocapillaris Flow Voids in Patients With Geographic Atrophy Using Swept-Source OCT Angiography.
  Ophthalmic surgery, lasers & imaging retina 2019 Rinella NT, Zhou H, Zhang Q, Keiner C, Oldenburg CE, Duncan JL, Wang RK, Schwartz DM
• Quantifying choriocapillaris hypoperfusion in patients with choroidal neovascularization using swept-source OCT angiography.
  Clinical ophthalmology (Auckland, N.Z.) 2019 Keiner CM, Zhou H, Zhang Q, Wang RK, Rinella NT, Oldenburg CE, Duncan JL, Schwartz DM
• Influence of eye pigmentation on retinal degeneration in P23H and S334ter mutant rhodopsin transgenic rats.
  Experimental eye research 2019 Lowe RJ, Daniello KM, Duncan JL, Yang H, Yasumura D, Matthes MT, LaVail MM
• Loss of Foveal Cone Structure Precedes Loss of Visual Acuity in Patients With Rod-Cone Degeneration.
  Investigative ophthalmology & visual science 2019 Bensinger E, Rinella N, Saud A, Loumou P, Ratnam K, Griffin S, Qin J, Porco TC, Roorda A, Duncan JL
• Ciliary Neurotrophic Factor Treatment Improves Retinal Structure and Function in Macular Telangiectasia Type 2.
  Ophthalmology 2019 Duncan JL
• Understanding Ocular Inflammation in Eyes Treated With Intravitreal Gene Therapy.
  JAMA ophthalmology 2019 Duncan JL
• Cone Spacing Correlates With Retinal Thickness and Microperimetry in Patients With Inherited Retinal Degenerations.
  Investigative ophthalmology & visual science 2019 Foote KG, De la Huerta I, Gustafson K, Baldwin A, Zayit-Soudry S, Rinella N, Porco TC, Roorda A, Duncan JL
• Diagnosis and Complementary Examinations.
  Cell-Based Therapy for Degenerative Retinal Disease 2019 Young Ju Lew, Jacque L. Duncan
• Dysflective Cones.
  Advances in experimental medicine and biology 2019 Duncan JL, Roorda A
• Multimodal Imaging in Choroideremia.
  Advances in experimental medicine and biology 2019 Foote KG, Roorda A, Duncan JL
• OCT Angiography and Cone Photoreceptor Imaging in Geographic Atrophy.
  Investigative ophthalmology & visual science 2018 Qin J, Rinella N, Zhang Q, Zhou H, Wong J, Deiner M, Roorda A, Porco TC, Wang RK, Schwartz DM, Duncan JL
• Cobalamin D Deficiency Identified Through Newborn Screening.
  JIMD reports 2018 Abu-El-Haija A, Mendelsohn BA, Duncan JL, Moore AT, Glenn OA, Weisiger K, Gallagher RC
• Inherited Retinal Degenerations: Current Landscape and Knowledge Gaps.
  Translational vision science & technology 2018 Duncan JL, Pierce EA, Laster AM, Daiger SP, Birch DG, Ash JD, Iannaccone A, Flannery JG, Sahel JA, Zack DJ, Zarbin MA, and the Foundation Fighting Blindness Scientific Advisory Board
• Relationship Between Foveal Cone Structure and Visual Acuity Measured With Adaptive Optics Scanning Laser Ophthalmoscopy in Retinal Degeneration.
  Investigative ophthalmology & visual science 2018 Foote KG, Loumou P, Griffin S, Qin J, Ratnam K, Porco TC, Roorda A, Duncan JL
• A mutation in IFT43 causes non-syndromic recessive retinal degeneration.
  Human molecular genetics 2017 Biswas P, Duncan JL, Ali M, Matsui H, Naeem MA, Raghavendra PB, Frazer KA, Arts HH, Riazuddin S, Akram J, Hejtmancik JF, Riazuddin SA, Ayyagari R
• High-resolution Imaging in Male Germ Cell-Associated Kinase (MAK)-related Retinal Degeneration.
  American journal of ophthalmology 2017 Lew YJ, Rinella N, Qin J, Chiang J, Moore AT, Porco TC, Roorda A, Duncan JL
• Phenotypic characterization of P23H and S334ter rhodopsin transgenic rat models of inherited retinal degeneration.
  Experimental eye research 2017 LaVail MM, Nishikawa S, Steinberg RH, Naash MI, Duncan JL, Trautmann N, Matthes MT, Yasumura D, Lau-Villacorta C, Chen J, Peterson WM, Yang H, Flannery JG
• Correction: Gustafson et al., Whole Genome Sequencing Revealed Mutations in Two Independent Genes as the Underlying Cause of Retinal Degeneration in an Ashkenazi Jewish Pedigree. Genes 2017, 8, 210.
  Genes 2017 Gustafson K, Duncan JL, Biswas P, Soto-Hermida A, Matsui H, Jakubosky D, Suk J, Telenti A, Frazer KA, Ayyagari R
• High prevalence of psychiatric and substance use disorders among persons seeking treatment for HIV and other STIs in Jamaica: a short report.
  AIDS care 2017 Beckford Jarrett S, De La Haye W, Miller Z, Figueroa JP, Duncan J, Harvey K
• Whole Genome Sequencing Revealed Mutations in Two Independent Genes as the Underlying Cause of Retinal Degeneration in an Ashkenazi Jewish Pedigree.
  Genes 2017 Gustafson K, Duncan JL, Biswas P, Soto-Hermida A, Matsui H, Jakubosky D, Suk J, Telenti A, Frazer KA, Ayyagari R
• Report From the NEI/FDA Endpoints Workshop on Age-Related Macular Degeneration and Inherited Retinal Diseases.
  Investigative ophthalmology & visual science 2017 Csaky K, Ferris F, Chew EY, Nair P, Cheetham JK, Duncan JL
• Photoreceptor-Based Biomarkers in AOSLO Retinal Imaging.
  Investigative ophthalmology & visual science 2017 Litts KM, Cooper RF, Duncan JL, Carroll J
• Dysflective cones: Visual function and cone reflectivity in long-term follow-up of acute bilateral foveolitis.
  American journal of ophthalmology case reports 2017 Tu JH, Foote KG, Lujan BJ, Ratnam K, Qin J, Gorin MB, Cunningham ET, Tuten WS, Duncan JL, Roorda A
• Inner retinal dystrophy in a patient with biallelic sequence variants in BRAT1.
  Ophthalmic genetics 2017 Oatts JT, Duncan JL, Hoyt CS, Slavotinek AM, Moore AT
• Visual Consequences of Delivering Therapies to the Subretinal Space.
  JAMA ophthalmology 2017 Duncan JL
• Genetic analysis of 10 pedigrees with inherited retinal degeneration by exome sequencing and phenotype-genotype association.
  Physiological genomics 2017 Biswas P, Duncan JL, Maranhao B, Kozak I, Branham K, Gabriel L, Lin JH, Barteselli G, Navani M, Suk J, Parke M, Schlechter C, Weleber RG, Heckenlively JR, Dagnelie G, Lee P, Riazuddin SA, Ayyagari R
• Ocular findings in a patient with fucosidosis.
  American journal of ophthalmology case reports 2016 Sánchez LR, Oatts JT, Duncan JL, Packman S, Moore AT
• Performance of real-world functional vision tasks by blind subjects improves after implantation with the Argus® II retinal prosthesis system.
  Clinical & experimental ophthalmology 2016 Dagnelie G, Christopher P, Arditi A, da Cruz L, Duncan JL, Ho AC, Olmos de Koo LC, Sahel JA, Stanga PE, Thumann G, Wang Y, Arsiero M, Dorn JD, Greenberg RJ, Argus® II Study Group
• Improvements in vision-related quality of life in blind patients implanted with the Argus II Epiretinal Prosthesis.
  Clinical & experimental optometry 2016 Duncan JL, Richards TP, Arditi A, da Cruz L, Dagnelie G, Dorn JD, Ho AC, Olmos de Koo LC, Barale PO, Stanga PE, Thumann G, Wang Y, Greenberg RJ
• Long-term Follow-up of Patients With Retinitis Pigmentosa Receiving Intraocular Ciliary Neurotrophic Factor Implants.
  American journal of ophthalmology 2016 Birch DG, Bennett LD, Duncan JL, Weleber RG, Pennesi ME
• Five-Year Safety and Performance Results from the Argus II Retinal Prosthesis System Clinical Trial.
  Ophthalmology 2016 da Cruz L, Dorn JD, Humayun MS, Dagnelie G, Handa J, Barale PO, Sahel JA, Stanga PE, Hafezi F, Safran AB, Salzmann J, Santos A, Birch D, Spencer R, Cideciyan AV, de Juan E, Duncan JL, Eliott D, Fawzi …
• A missense mutation in ASRGL1 is involved in causing autosomal recessive retinal degeneration.
  Human molecular genetics 2016 Biswas P, Chavali VR, Agnello G, Stone E, Chakarova C, Duncan JL, Kannabiran C, Homsher M, Bhattacharya SS, Naeem MA, Kimchi A, Sharon D, Iwata T, Riazuddin S, Reddy GB, Hejtmancik JF, Georgiou G, …
• Col4a1 mutations cause progressive retinal neovascular defects and retinopathy.
  Scientific reports 2016 Alavi MV, Mao M, Pawlikowski BT, Kvezereli M, Duncan JL, Libby RT, John SW, Gould DB
• An analysis of observer-rated functional vision in patients implanted with the Argus II Retinal Prosthesis System at three years.
  Clinical & experimental optometry 2016 Geruschat DR, Richards TP, Arditi A, da Cruz L, Dagnelie G, Dorn JD, Duncan JL, Ho AC, Olmos de Koo LC, Sahel JA, Stanga PE, Thumann G, Wang V, Greenberg RJ
• Adaptive optics ophthalmoscopy.
  Annual review of vision science 2015 Roorda A, Duncan JL
• Repeatability of Cone Spacing Measures in Eyes With Inherited Retinal Degenerations.
  Investigative ophthalmology & visual science 2015 Zayit-Soudry S, Sippl-Swezey N, Porco TC, Lynch SK, Syed R, Ratnam K, Menghini M, Roorda AJ, Duncan JL
• DIRECTIONAL OPTICAL COHERENCE TOMOGRAPHY PROVIDES ACCURATE OUTER NUCLEAR LAYER AND HENLE FIBER LAYER MEASUREMENTS.
  Retina (Philadelphia, Pa.) 2015 Lujan BJ, Roorda A, Croskrey JA, Dubis AM, Cooper RF, Bayabo JK, Duncan JL, Antony BJ, Carroll J
• Spontaneous Regeneration of Human Photoreceptor Outer Segments.
  Scientific reports 2015 Horton JC, Parker AB, Botelho JV, Duncan JL
• Correlation of Serial Scleral and Corneal Pneumatonometry.
  Ophthalmology 2015 Kuo DS, Ou Y, Jeng BH, Bhisitkul R, Stewart JM, Duncan JL, Han Y
• Long-Term Results from an Epiretinal Prosthesis to Restore Sight to the Blind.
  Ophthalmology 2015 Ho AC, Humayun MS, Dorn JD, da Cruz L, Dagnelie G, Handa J, Barale PO, Sahel JA, Stanga PE, Hafezi F, Safran AB, Salzmann J, Santos A, Birch D, Spencer R, Cideciyan AV, de Juan E, Duncan JL, Eliott D,…
• Adaptive optics microperimetry and OCT images show preserved function and recovery of cone visibility in macular telangiectasia type 2 retinal lesions.
  Investigative ophthalmology & visual science 2015 Wang Q, Tuten WS, Lujan BJ, Holland J, Bernstein PS, Schwartz SD, Duncan JL, Roorda A
• Correlation of outer nuclear layer thickness with cone density values in patients with retinitis pigmentosa and healthy subjects.
  Investigative ophthalmology & visual science 2014 Menghini M, Lujan BJ, Zayit-Soudry S, Syed R, Porco TC, Bayabo K, Carroll J, Roorda A, Duncan JL
• Effects of the absence of apolipoprotein e on lipoproteins, neurocognitive function, and retinal function.
  JAMA neurology 2014 Mak AC, Pullinger CR, Tang LF, Wong JS, Deo RC, Schwarz JM, Gugliucci A, Movsesyan I, Ishida BY, Chu C, Poon A, Kim P, Stock EO, Schaefer EJ, Asztalos BF, Castellano JM, Wyss-Coray T, Duncan JL, …
• Ocular Phenotype of a Family with FAM161A-associated Retinal Degeneration.
  Ophthalmic genetics 2014 Duncan JL, Biswas P, Kozak I, Navani M, Syed R, Soudry S, Menghini M, Caruso RC, Jeffrey BG, Heckenlively JR, Reddy GB, Lee P, Roorda A, Ayyagari R
• The reliability of parafoveal cone density measurements.
  The British journal of ophthalmology 2014 Liu BS, Tarima S, Visotcky A, Pechauer A, Cooper RF, Landsem L, Wilk MA, Godara P, Makhijani V, Sulai YN, Syed N, Yasumura G, Garg AK, Pennesi ME, Lujan BJ, Dubra A, Duncan JL, Carroll J
• Diagnosis and complementary examinations.
  Developments in ophthalmology 2014 Menghini M, Duncan JL
• Retinal hemangioblastoma.
  JAMA ophthalmology 2014 Gorovoy IR, Duncan JL
• Mutations in the small nuclear riboprotein 200 kDa gene (SNRNP200) cause 1.6% of autosomal dominant retinitis pigmentosa.
  Molecular vision 2013 Bowne SJ, Sullivan LS, Avery CE, Sasser EM, Roorda A, Duncan JL, Wheaton DH, Birch DG, Branham KE, Heckenlively JR, Sieving PA, Daiger SP
• Cone structure imaged with adaptive optics scanning laser ophthalmoscopy in eyes with nonneovascular age-related macular degeneration.
  Investigative ophthalmology & visual science 2013 Zayit-Soudry S, Duncan JL, Syed R, Menghini M, Roorda AJ
• Quinacrine treatment trial for sporadic Creutzfeldt-Jakob disease.
  Neurology 2013 Geschwind MD, Kuo AL, Wong KS, Haman A, Devereux G, Raudabaugh BJ, Johnson DY, Torres-Chae CC, Finley R, Garcia P, Thai JN, Cheng HQ, Neuhaus JM, Forner SA, Duncan JL, Possin KL, Dearmond SJ, Prusiner…
• Relationship between foveal cone structure and clinical measures of visual function in patients with inherited retinal degenerations.
  Investigative ophthalmology & visual science 2013 Ratnam K, Carroll J, Porco TC, Duncan JL, Roorda A
• Adaptive Optics Scanning Laser Ophthalmoscopy (AOSLO).
  Advanced Biophotonics 2013 Yuhua Zhang, Christopher Girkin, Jacque Duncan, Austin Roorda
• Randomized trial of ciliary neurotrophic factor delivered by encapsulated cell intraocular implants for retinitis pigmentosa.
  American journal of ophthalmology 2013 Birch DG, Weleber RG, Duncan JL, Jaffe GJ, Tao W, Ciliary Neurotrophic Factor Retinitis Pigmentosa Study Groups
• High-resolution images of retinal structure in patients with choroideremia.
  Investigative ophthalmology & visual science 2013 Syed R, Sundquist SM, Ratnam K, Zayit-Soudry S, Zhang Y, Crawford JB, MacDonald IM, Godara P, Rha J, Carroll J, Roorda A, Stepien KE, Duncan JL
• Cone structure in patients with usher syndrome type III and mutations in the Clarin 1 gene.
  JAMA ophthalmology 2013 Ratnam K, Västinsalo H, Roorda A, Sankila EM, Duncan JL
• Mutations in RPGR and RP2 account for 15% of males with simplex retinal degenerative disease.
  Investigative ophthalmology & visual science 2012 Branham K, Othman M, Brumm M, Karoukis AJ, Atmaca-Sonmez P, Yashar BM, Schwartz SB, Stover NB, Trzupek K, Wheaton D, Jennings B, Ciccarelli ML, Jayasundera KT, Lewis RA, Birch D, Bennett J, Sieving PA…
• Identification of a novel mutation in the CDHR1 gene in a family with recessive retinal degeneration.
  Archives of ophthalmology (Chicago, Ill. : 1960) 2012 Duncan JL, Roorda A, Navani M, Vishweswaraiah S, Syed R, Soudry S, Ratnam K, Gudiseva HV, Lee P, Gaasterland T, Ayyagari R
• Discordant anatomical, electrophysiological, and visual behavioral profiles of retinal degeneration in rat models of retinal degenerative disease.
  Investigative ophthalmology & visual science 2012 McGill TJ, Prusky GT, Douglas RM, Yasumura D, Matthes MT, Lowe RJ, Duncan JL, Yang H, Ahern K, Daniello KM, Silver B, LaVail MM
• Macular Degeneration, Age Related.
  eLS 2012 Shiri Zayit-Soudry, Jacque L Duncan
• Interim results from the international trial of Second Sight's visual prosthesis.
  Ophthalmology 2012 Humayun MS, Dorn JD, da Cruz L, Dagnelie G, Sahel JA, Stanga PE, Cideciyan AV, Duncan JL, Eliott D, Filley E, Ho AC, Santos A, Safran AB, Arditi A, Del Priore LV, Greenberg RJ, Argus II Study Group
• Abnormal cone structure in foveal schisis cavities in X-linked retinoschisis from mutations in exon 6 of the RS1 gene.
  Investigative ophthalmology & visual science 2011 Duncan JL, Ratnam K, Birch DG, Sundquist SM, Lucero AS, Zhang Y, Meltzer M, Smaoui N, Roorda A
• Outer retinal structure in patients with acute zonal occult outer retinopathy.
  American journal of ophthalmology 2011 Mkrtchyan M, Lujan BJ, Merino D, Thirkill CE, Roorda A, Duncan JL
• Growth Factor Therapy for Retinal Neuroprotection.
  Retinal Physician 2011 REEMA SYED, JACQUE L. DUNCAN
• Observation of cone and rod photoreceptors in normal subjects and patients using a new generation adaptive optics scanning laser ophthalmoscope.
  Biomedical optics express 2011 Merino D, Duncan JL, Tiruveedhula P, Roorda A
• Cone photoreceptor abnormalities correlate with vision loss in patients with Stargardt disease.
  Investigative ophthalmology & visual science 2011 Chen Y, Ratnam K, Sundquist SM, Lujan B, Ayyagari R, Gudiseva VH, Roorda A, Duncan JL
• Longitudinal study of cone photoreceptors during retinal degeneration and in response to ciliary neurotrophic factor treatment.
  Investigative ophthalmology & visual science 2011 Talcott KE, Ratnam K, Sundquist SM, Lucero AS, Lujan BJ, Tao W, Porco TC, Roorda A, Duncan JL
• BBS genotype-phenotype assessment of a multiethnic patient cohort calls for a revision of the disease definition.
  Human mutation 2011 Deveault C, Billingsley G, Duncan JL, Bin J, Theal R, Vincent A, Fieggen KJ, Gerth C, Noordeh N, Traboulsi EI, Fishman GA, Chitayat D, Knueppel T, Millán JM, Munier FL, Kennedy D, Jacobson SG, Innes …
• Cone structure in retinal degeneration associated with mutations in the peripherin/RDS gene.
  Investigative ophthalmology & visual science 2011 Duncan JL, Talcott KE, Ratnam K, Sundquist SM, Lucero AS, Day S, Zhang Y, Roorda A
• Visual field loss in patients with cytomegalovirus retinitis.
  Ophthalmology 2010 Thorne JE, Van Natta ML, Jabs DA, Duncan JL, Srivastava SK, Studies of Ocular Complications of AIDS Research Group
• Adaptive optics retinal imaging: emerging clinical applications.
  Optometry and vision science : official publication of the American Academy of Optometry 2010 Godara P, Dubis AM, Roorda A, Duncan JL, Carroll J
• Heterogeneous patterns of tissue injury in NARP syndrome.
  Journal of neurology 2010 Gelfand JM, Duncan JL, Racine CA, Gillum LA, Chin CT, Zhang Y, Zhang Q, Wong LJ, Roorda A, Green AJ
• Mutations in chaperonin-like BBS genes are a major contributor to disease development in a multiethnic Bardet-Biedl syndrome patient population.
  Journal of medical genetics 2010 Billingsley G, Bin J, Fieggen KJ, Duncan JL, Gerth C, Ogata K, Wodak SS, Traboulsi EI, Fishman GA, Paterson A, Chitayat D, Knueppel T, Millán JM, Mitchell GA, Deveault C, Héon E
• Intense cyclic light-induced retinal degeneration in rats.
  Archives of ophthalmology (Chicago, Ill. : 1960) 2010 Duncan JL, LaVail MM
• Retinal vascular abnormalities and dragged maculae in a carrier with a new NDP mutation (c.268delC) that caused severe Norrie disease in the proband.
  Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus 2010 Lin P, Shankar SP, Duncan J, Slavotinek A, Stone EM, Rutar T
• Advances in imaging of Stargardt disease.
  Advances in experimental medicine and biology 2010 Chen Y, Roorda A, Duncan JL
• Phenotypic variability due to a novel Glu292Lys variation in exon 8 of the BEST1 gene causing best macular dystrophy.
  Archives of ophthalmology (Chicago, Ill. : 1960) 2009 Sohn EH, Francis PJ, Duncan JL, Weleber RG, Saperstein DA, Farrell DF, Stone EM
• Sustained delivery of NT-3 from lens fiber cells in transgenic mice reveals specificity of neuroprotection in retinal degenerations.
  The Journal of comparative neurology 2008 Lavail MM, Nishikawa S, Duncan JL, Yang H, Matthes MT, Yasumura D, Vollrath D, Overbeek PA, Ash JD, Robinson ML
• Adaptive optics scanning laser ophthalmoscopy images in a family with the mitochondrial DNA T8993C mutation.
  Investigative ophthalmology & visual science 2008 Yoon MK, Roorda A, Zhang Y, Nakanishi C, Wong LJ, Zhang Q, Gillum L, Green A, Duncan JL
• Retinal TrkB receptors regulate neural development in the inner, but not outer, retina.
  Molecular and cellular neurosciences 2008 Grishanin RN, Yang H, Liu X, Donohue-Rolfe K, Nune GC, Zang K, Xu B, Duncan JL, Lavail MM, Copenhagen DR, Reichardt LF
• Intraocular CNTF reduces vision in normal rats in a dose-dependent manner.
  Investigative ophthalmology & visual science 2007 McGill TJ, Prusky GT, Douglas RM, Yasumura D, Matthes MT, Nune G, Donohue-Rolfe K, Yang H, Niculescu D, Hauswirth WW, Girman SV, Lund RD, Duncan JL, LaVail MM
• Rapid and stable knockdown of an endogenous gene in retinal pigment epithelium.
  Human gene therapy 2007 Paskowitz DM, Greenberg KP, Yasumura D, Grimm D, Yang H, Duncan JL, Kay MA, Lavail MM, Flannery JG, Vollrath D
• Vesicular glutamate transporter 1 is required for photoreceptor synaptic signaling but not for intrinsic visual functions.
  The Journal of neuroscience : the official journal of the Society for Neuroscience 2007 Johnson J, Fremeau RT, Duncan JL, Rentería RC, Yang H, Hua Z, Liu X, LaVail MM, Edwards RH, Copenhagen DR
• High-resolution imaging with adaptive optics in patients with inherited retinal degeneration.
  Investigative ophthalmology & visual science 2007 Duncan JL, Zhang Y, Gandhi J, Nakanishi C, Othman M, Branham KE, Swaroop A, Roorda A
• High-resolution in vivo imaging of the RPE mosaic in eyes with retinal disease.
  Investigative ophthalmology & visual science 2007 Roorda A, Zhang Y, Duncan JL
• Molecular and cellular alterations induced by sustained expression of ciliary neurotrophic factor in a mouse model of retinitis pigmentosa.
  Investigative ophthalmology & visual science 2007 Rhee KD, Ruiz A, Duncan JL, Hauswirth WW, Lavail MM, Bok D, Yang XJ
• Neurotrophic factors minimize the retinal toxicity of verteporfin photodynamic therapy.
  Investigative ophthalmology & visual science 2007 Paskowitz DM, Donohue-Rolfe KM, Yang H, Yasumura D, Matthes MT, Hosseini K, Graybeal CM, Nune G, Zarbin MA, Lavail MM, Duncan JL
• Factors affecting attrition in a longitudinal study of patients with AIDS.
  AIDS care 2006 Brown DM, Thorne JE, Foster GL, Duncan JL, Brune LM, Muñana A, Meinert CL, Jabs DA
• Scotopic visual signaling in the mouse retina is modulated by high-affinity plasma membrane calcium extrusion.
  The Journal of neuroscience : the official journal of the Society for Neuroscience 2006 Duncan JL, Yang H, Doan T, Silverstein RS, Murphy GJ, Nune G, Liu X, Copenhagen D, Tempel BL, Rieke F, Krizaj D
• Correlation between clinical suspicion and polymerase chain reaction verification of infectious vitritis.
  American journal of ophthalmology 2006 Acharya N, Lietman T, Cevallos V, Whitcher JP, Saidel M, Stone D, Duncan J, Margolis TP
• Preface.
  International Ophthalmology Clinics 2006 Jacque L. Duncan, James Palmer
• Retinal damage caused by photodynamic therapy can be reduced using BDNF.
  Advances in experimental medicine and biology 2006 Duncan JL, Paskowitz DM, Nune GC, Yasumura D, Yang H, Matthes MT, Zarbin MA, LaVail MM
• Mouse models may provide new insight into the relation between cholesterol and age related macular degeneration.
  The British journal of ophthalmology 2005 Duncan JL
• Bilateral endogenous Scedosporium prolificans endophthalmitis after lung transplantation.
  American journal of ophthalmology 2005 Vagefi MR, Kim ET, Alvarado RG, Duncan JL, Howes EL, Crawford JB
• Macular schisis detachment associated with angle-closure glaucoma.
  Archives of ophthalmology (Chicago, Ill. : 1960) 2005 Hollander DA, Barricks ME, Duncan JL, Irvine AR
• Acute zonal occult outer retinopathy in a patient with graft-versus-host disease.
  American journal of ophthalmology 2004 Cheung MC, Nune GC, Hwang DG, Sutter EE, Duncan JL
• Deficiency of pantothenate kinase 2 (Pank2) in mice leads to retinal degeneration and azoospermia.
  Human molecular genetics 2004 Kuo YM, Duncan JL, Westaway SK, Yang H, Nune G, Xu EY, Hayflick SJ, Gitschier J
• BDNF reduces the retinal toxicity of verteporfin photodynamic therapy.
  Investigative ophthalmology & visual science 2004 Paskowitz DM, Nune G, Yasumura D, Yang H, Bhisitkul RB, Sharma S, Matthes MT, Zarbin MA, Lavail MM, Duncan JL
• Statin and aspirin therapy are associated with decreased rates of choroidal neovascularization among patients with age-related macular degeneration.
  American journal of ophthalmology 2004 Wilson HL, Schwartz DM, Bhatt HR, McCulloch CE, Duncan JL
• Detection of localized retinal dysfunction in a choroideremia carrier.
  American journal of ophthalmology 2004 Cheung MC, Nune GC, Wang M, McTaggart KE, MacDonald IM, Duncan JL
• An RCS-like retinal dystrophy phenotype in mer knockout mice.
  Investigative ophthalmology & visual science 2003 Duncan JL, LaVail MM, Yasumura D, Matthes MT, Yang H, Trautmann N, Chappelow AV, Feng W, Earp HS, Matsushima GK, Vollrath D
• Macular Degeneration, Age Related.
  eLS 2003 Jacque L Duncan, Jeffrey W Berger, Stuart L Fine
• Inherited retinal dystrophy in Mer knockout mice.
  Advances in experimental medicine and biology 2003 Duncan JL, Yang H, Vollrath D, Yasumura D, Matthes MT, Trautmann N, Chappelow AV, Feng W, Earp HS, Matsushima GK, LaVail MM
• Effects of adeno-associated virus-vectored ciliary neurotrophic factor on retinal structure and function in mice with a P216L rds/peripherin mutation.
  Experimental eye research 2002 Bok D, Yasumura D, Matthes MT, Ruiz A, Duncan JL, Chappelow AV, Zolutukhin S, Hauswirth W, LaVail MM
• Macular pigment and lutein supplementation in choroideremia.
  Experimental eye research 2002 Duncan JL, Aleman TS, Gardner LM, De Castro E, Marks DA, Emmons JM, Bieber ML, Steinberg JD, Bennett J, Stone EM, MacDonald IM, Cideciyan AV, Maguire MG, Jacobson SG
• Correction of the retinal dystrophy phenotype of the RCS rat by viral gene transfer of Mertk.
  Proceedings of the National Academy of Sciences of the United States of America 2001 Vollrath D, Feng W, Duncan JL, Yasumura D, D'Cruz PM, Chappelow A, Matthes MT, Kay MA, LaVail MM
• Macular pigment and lutein supplementation in retinitis pigmentosa and Usher syndrome.
  Investigative ophthalmology & visual science 2001 Aleman TS, Duncan JL, Bieber ML, de Castro E, Marks DA, Gardner LM, Steinberg JD, Cideciyan AV, Maguire MG, Jacobson SG
• Linear nevus sebaceous syndrome: Authors’ reply.
  Ophthalmology 1999 Jacque L Duncan, Emmett T Cunningham
• 6-substituted tricyclic partial ergoline compounds are selective and potent 5-hydroxytryptamine1A receptor agents.
  Life sciences 1990 Slaughter JL, Harrington MA, Peroutka SJ