Jacob Young, MD
Assistant Professor
Neurological Surgery
School of Medicine

His clinical research explores how to optimize functional outcomes and minimize complications after surgery for intrinsic brain tumors.

Dr. Young's translational research interests include first-in-human early-phase clinical trials of new immunotherapies and innovative ways to deliver drugs to treat cancerous brain tumors. In his lab, he focuses on understanding the microenvironment of glioma and how it contributes to intratumoral heterogeneity (differences between cancer cells within the same tumor), treatment resistance and cancer evolution at the time of progression. Working with numerous collaborators, his ultimate goal is to design treatment strategies that improve outcomes for patients with brain tumors. His glioblastoma research has been recognized at the institutional, regional, and national levels. During his postdoctoral training, he was awarded the Chan Zuckerberg Biohub Physician-Scientist fellowship, the Andrew J. Lockhart Focused Ultrasound and Immuno-Oncology fellowship, and the American Society of Clinical Oncology Young Investigator Award.

Dr. Young earned his medical degree from the University of Chicago Pritzker School of Medicine, where he was elected to the Alpha Omega Alpha Honor Medical Society. He completed a residency in neurosurgery and a postdoctoral fellowship in tumor immunology at UCSF, where he received an Exceptional Physician Award during his training. He was recognized with the Krevan's Award for excellence in patient care at the Zuckerberg San Francisco General Hospital and the Howard Naffziger Award for Outstanding Clinical Service from the department of neurological surgery.

• Radiation-induced sarcoma after glioma resection in patients with Li-Fraumeni syndrome: illustrative cases.
  Journal of neurosurgery. Case lessons 2025 Kondapavulur S, Young JS, Berger MS
• The Intraoperative Utility of Raman Spectroscopy for Neurosurgical Oncology.
  Cancers 2025 Chen JS, Oh JY, Hollon TC, Hervey-Jumper SL, Young JS, Berger MS
• A prognostic classification system for extent of resection in IDH-mutant grade 2 glioma: an international, multicentre, retrospective cohort study with external validation by the RANO resect group.
  The Lancet. Oncology 2025 Karschnia P, Young JS, Wijnenga MMJ, Sciortino T, Teske N, Corell A, Wagner A, Youssef G, Park YW, Häni L, Jünger ST, Dono A, Ehret F, Mireles EEM, Neidert N, Bruno F, Tuchek CA, van der Vaart T, …
• SURG-57. AI-based quantification of tumor infiltration as a major determinant of glioblastoma recurrence and predictive modeling.
  Neuro-Oncology 2025 Sanjeev Herr, Niels Olshausen, Melike Pekmezci, Jasleen Kaur, Youssef Sibih, Vardhaan Ambati, Katie Scotford, Amit Persad, Thiebaud Picart, Akhil Kondepudi, Nancy Ann Oberheim-Bush, Albert Kim, Jacob …
• Blood Ethanol Level Influences Presenting Glasgow Coma Scale Interpretation After Traumatic Brain Injury: A Transforming Research and Clinical Knowledge in Traumatic Brain Injury Study.
  Neurosurgery 2025 Peeran Z, Young JS, DiGiorgio AM, Haddad AF, Markowitz AJ, Grandhi R, Temkin NR, Barber J, Manley GT
• JS09.5.A SPATIAL TRANSCRIPTOMIC AND ELECTRODIAGNOSTIC PROFILING REVEALS SYNAPTIC CONNECTIVITY IS A HALLMARK OF OLIGODENDROGLIOMA RECURRENCE AND MALIGNANT TRANSFORMATION.
  Neuro-Oncology 2025 S Oten, K Mirchia, T Picart, M P Nguyen, V Ambati, H Vasudevan, J Young, J Taylor, S Krishna, D J Brang, J J Phillips, A Perry, M S Berger, S Chang, J de Groot, S Hervey-Jumper, D R Raleigh
• OS08.6.A A PROGNOSTIC CLASSIFICATION SYSTEM FOR EXTENT OF RESECTION IN IDH-MUTANT GRADE 2 GLIOMA: A REPORT BY THE RANO RESECT GROUP.
  Neuro-Oncology 2025 P Karschnia, J Young, M M Wijnenga, T Sciortino, N Teske, A Corell, A Wagner, G C Youssef, Y Park, L Häni, S T Juenger, A Dono, F Ehret, E E Mendoza Mireles, N Neidert, F Bruno, C Tuchek, T van der …
• OS11.5.A PREOPERATIVE ASSESSMENT OF TUMOR ELOQUENCE AND RESECTABILITY: AN INTERNATIONAL SURVEY.
  Neuro-Oncology 2025 E Rammeloo, J Young, J W Schouten, E Bos, S Hervey-Jumper, C Jungk, S M Krieg, T R Smith, J Rincon-Toroella, C Bettegowda, T Maruyama, A Wagner, P Schucht, M L Broekman, S De Vleeschouwer, B Nahed, M …
• P02.02.A IL6 UNDERLIES MICROENVIRONMENT IMMUNOSUPPRESSION AND RESISTANCE TO THERAPY IN GLIOBLASTOMA.
  Neuro-Oncology 2025 J S Young, N Cho, C G Lucas, K Seo, H Najem, K Mirchia, W C Chen, N Zakimi, V Daggubati, T Casey-Clyde, M P Nguyen, A Chen, J J Phillips, T Ozawa, M K Aghi, J W Taylor, J L DeRisi, A Bhaduri, A …
• P07.10.B INTER-RATER AGREEMENT FROM A MULTI-NATIONAL EXPERT PANEL ON RESECTABILITY OF RECURRENT GLIOBLASTOMA: A COMPLEMENTARY POST-HOC ANALYSIS OF THE PROSPECTIVE, RANDOMIZED DIRECTOR TRIAL.
  Neuro-Oncology 2025 P Karschnia, N Teske, E Le Rhun, H Wirsching, A S Jakola, C Roder, D P Cahill, E O Vik-Mo, M S Berger, J S Young, K J Drummond, L Bello, M L Broekman, M A Vogelbaum, Y Esquenazi, O Schnell, M Weller, …
• Correction to: Preoperative assessment of tumor eloquence and resectability: an international survey.
  Journal of neuro-oncology 2025 Rammeloo E, Young JS, Schouten JW, Bos EM, Hervey-Jumper SL, Jungk C, Krieg SM, Smith T, Rincon-Torroella J, Bettegowda C, Maruyama T, Wagner A, Schucht P, Broekman MLD, De Vleeschouwer S, Nahed BV, …
• Point/counterpoint: The role of re-resection in recurrent glioblastoma.
  Neuro-oncology 2025 Young JS, Berger MS, Lasocki A, Suwala AK, Niyazi M, Chang SM, Schnell O, Karschnia P
• Tumor heterogeneity underlies clinical outcome and MEK inhibitor response in somatic NF1-mutant glioblastoma.
  JCI insight 2025 Pan S, Mirchia K, Payne E, Liu SJ, Al-Adli N, Peeran Z, Shukla P, Young JS, Gupta R, Wu J, Pak J, Ozawa T, Na B, Reddy AT, Braunstein SE, Phillips JJ, Chang S, Solomon DA, Perry A, Raleigh DR, Berger …
• Management of glioma-associated epilepsy in the molecular era: a review of the literature and an institutional experience.
  Neurosurgical focus 2025 Shukla PD, Nguyen MP, Lee AT, Chang EF, Young JS
• Correlation between time to postoperative seizure onset and time to tumor progression in a cohort of adult-type diffuse gliomas with molecular characterization.
  Journal of neurosurgery 2025 Nguyen MP, Shukla PD, Lee AT, Chang EF, Young JS
• Functional Gonadotroph Adenomas in Male Patients: Clinical Characteristics, Surgical Outcomes, and Hormonal Follow-up.
  Operative neurosurgery (Hagerstown, Md.) 2025 Peeran Z, Osorio RC, Perez M, Kabir AS, Mehari M, Dada A, Badani A, Khela HS, Young JS, El-Sayed IH, Gurrola JG, Theodosopoulos P, Blevins L, Kunwar S, Aghi MK
• Ipsilateral tumor-side-down approach to mesial parietal and occipital gliomas: patient series.
  Journal of neurosurgery. Case lessons 2025 Elguindy MM, Bernabei JM, Young JS, Berger MS
• Practical and statistical aspects of subgroup analyses in surgical neuro-oncology: A comprehensive review from the PIONEER consortium.
  Neuro-oncology 2025 Gerritsen JKW, Karschnia P, Young JS, van den Bent MJ, Chang SM, Smith TR, Nahed BV, Rincon-Torroella J, Bettegowda C, Sanai N, Krieg SM, Maruyama T, Schucht P, Broekman MLD, Tonn JC, Wen PY, De …
• The role of Lobectomy in Glioblastoma management: A Retrospective series.
  Brain & spine 2025 Arvaniti CK, Brotis AG, Young JS, Sivanrupan S, Menna G, Nishide M, Schucht P, Berger M, Fountas KN
• A prognostic classification system for extent of resection in IDH-mutant grade 2 glioma: A report by the RANO resect group.
  Journal of Clinical Oncology 2025 Philipp Karschnia, Jacob S. Young, Maarten Wijnenga, Arthur Wagner, Oliver Schnell, Levin Häni, Yoshua Esquenazi, Einar Vik-Mo, Roberta Rudà, Michael A. Vogelbaum, Shawn L. Hervey-Jumper, Juergen Beck…
• Glioma-neuronal circuit remodeling induces regional immunosuppression.
  Nature communications 2025 Nejo T, Krishna S, Yamamichi A, Lakshmanachetty S, Jimenez C, Lee KY, Baker DL, Young JS, Chen T, Phyu SSS, Phung L, Gallus M, Maldonado GC, Okada K, Ogino H, Watchmaker PB, Diebold D, Choudhury A, …
• Preoperative assessment of tumor eloquence and resectability: an international survey.
  Journal of neuro-oncology 2025 Rammeloo E, Young JS, Schouten JW, Bos EM, Hervey-Jumper SL, Jungk C, Krieg SM, Smith T, Rincon-Torroella J, Bettegowda C, Maruyama T, Wagner A, Schucht P, Broekman MLD, De Vleeschouwer S, Nahed BV, …
• Development and validation of a clinical risk model for postoperative outcome in newly diagnosed glioblastoma: A report of the RANO resect group.
  Neuro-oncology 2025 Karschnia P, Young JS, Youssef GC, Dono A, Häni L, Sciortino T, Bruno F, Juenger ST, Teske N, Dietrich J, Weller M, Vogelbaum MA, van den Bent M, Beck J, Thon N, Gerritsen JKW, Hervey-Jumper S, Cahill…
• Current and Future Applications of 5-Aminolevulinic Acid in Neurosurgical Oncology.
  Cancers 2025 Chen JS, Young JS, Berger MS
• 1330 The Impact of Systemic Disease Status on Postoperative Outcomes After Resection of Brain Metastases: A Single Center Study.
  Neurosurgery 2025 Tony Catalan, Austin Lui, Jacob Young, Philip V. Theodosopoulos, Shawn L. Hervey-Jumper, Manish Kumar Aghi, Ramin Morshed
• 1337 The Impact of Brain Metastasis Multiplicity on Postoperative Survival and CNS Progression: A Single Center Study.
  Neurosurgery 2025 Austin Lui, Tony Catalan, Jacob Young, Philip V. Theodosopoulos, Shawn L. Hervey-Jumper, Manish Kumar Aghi, Ramin Morshed
• Simulation tools in neuro-oncological surgery: a scoping review of perioperative and training applications.
  Journal of neuro-oncology 2025 Menna G, Riva D, Marino S, Garber J, Gerritsen JKW, Mattogno PP, Young JS, Olivi A, Doglietto F, Berger MS, Della Pepa GM
• IL-6 underlies microenvironment immunosuppression and resistance to therapy in glioblastoma.
  bioRxiv : the preprint server for biology 2025 Young JS, Cho NW, Lucas CG, Najem H, Mirchia K, Chen WC, Seo K, Zakimi N, Daggubati V, Casey-Clyde T, Nguyen MP, Chen A, Phillips JJ, Ozawa T, Aghi MK, Taylor JW, DeRisi JL, Bhaduri A, Berger MS, …
• Association of lower tumor mutation burden with rapid local progression in patients with brain metastases.
  Journal of neurosurgery 2025 Shukla PD, Nguyen MP, Lui A, Catalan T, Young JS, Berger MS, Theodosopoulos PV, Hervey-Jumper SL, Huppert LA, Aghi MK, Vasudevan HN, Morshed RA
• Chimeric antigen receptor T-cell therapy in patients with malignant glioma-From neuroimmunology to clinical trial design considerations.
  Neuro-oncology 2025 Gallus M, Young JS, Cook Quackenbush S, Khasraw M, de Groot J, Okada H
• Longitudinal profiling of IDH-mutant astrocytomas reveals acquired RAS-MAPK pathway mutations associated with inferior survival.
  Neuro-oncology advances 2025 Rodriguez Almaraz E, Guerra GA, Al-Adli NN, Young JS, Dada A, Quintana D, Taylor JW, Oberheim Bush NA, Clarke JL, Butowski NA, de Groot J, Pekmezci M, Perry A, Bollen AW, Scheffler AW, Glidden DV, …
• Focused ultrasound therapy as a strategy for improving glioma treatment.
  Journal of neurosurgery 2025 Young JS, Semonche A, Morshed RA, Al-Adli NN, Haddad AF, Gerritsen JKW, Saggi S, Narsinh K, de Groot J, Aghi MK
• Longitudinal multimodal profiling of IDH-wildtype glioblastoma reveals the molecular evolution and cellular phenotypes underlying prognostically different treatment responses.
  Neuro-oncology 2025 Lucas CG, Al-Adli NN, Young JS, Gupta R, Morshed RA, Wu J, Ravindranathan A, Shai A, Oberheim Bush NA, Taylor JW, de Groot J, Villanueva-Meyer JE, Pekmezci M, Perry A, Bollen AW, Theodosopoulos PV, …
• Development and validation of a novel prognostic classification system for extent of resection in IDH-mutant grade 2 glioma: a report by the RANO resect group.
  Brain and Spine 2025 Philipp Karschnia, Jacob S. Young, Maarten M.J. Wijnenga, Arthur Wagner, Oliver Schnell, Yoshua Esquenazi, Einar O. Vik-Mo, Roberta Rudà, Michael A. Vogelbaum, Shawn L. Hervey-Jumper, Jorg Dietrich, …
• Co-evolution of glioma and immune microenvironment.
  Journal for immunotherapy of cancer 2024 Elguindy MM, Young JS, Ho WS, Lu RO
• The impact of intraoperative mapping during re-resection in recurrent gliomas: a systematic review.
  Journal of neuro-oncology 2024 van Opijnen MP, Sadigh Y, Dijkstra ME, Young JS, Krieg SM, Ille S, Sanai N, Rincon-Torroella J, Maruyama T, Schucht P, Smith TR, Nahed BV, Broekman MLD, De Vleeschouwer S, Berger MS, Vincent AJPE, …
• CNSC-52. OLIGODENDROGLIOMA SPATIAL TRANSCRIPTOMIC SEQUENCING REVEALS THERAPY-DEPENDENT EVOLUTION OVER TIME.
  Neuro-Oncology 2024 Kanish Mirchia, Jacob Young, Minh Nguyen, Harish Vasudevan, John de Groot, David Raleigh
• EPID-28. TRENDS IN LOW GRADE GLIOMA PROGNOSIS AND THE EVOLVING IMPACT OF GROSS TOTAL RESECTION ACROSS FIFTY YEARS: A MULTICOHORT ANALYSIS.
  Neuro-Oncology 2024 Michael Jin, Jacob Young, Gray Umbach, Karthik Ravi, Michael Lim, Shawn Hervey-Jumper
• PATH-08. MOLECULAR DIVERGENCE RATES DIFFER BETWEEN BRAIN METASTASES AND EXTRACRANIAL DISEASE SITES ACROSS PRIMARY TUMOR HISTOLOGIES.
  Neuro-Oncology 2024 Ramin Morshed, Harmon Khela, Minh Nguyen, Jacob Young, Ezequiel Goldschmidt, Michael McDermott, Noor Malik, Ian Parney, Edward Chang, Mitchel Berger, Philip Theodosopoulos, Shawn Hervey-Jumper, Laura …
• PATH-53. DNA MUTATION SEQUENCING AND METHYLATION ANALYSIS OF SOMATICNF1 MUTANT IDH-WILDTYPE GLIOBLASTOMA IDENTIFIES THREE EPIGENETIC GROUPS ANDCDKN2A/B LOSS AS A NEGATIVE PROGNOSTIC BIOMARKER.
  Neuro-Oncology 2024 Kanish Mirchia, Sixuan Pan, Emily Payne, John Liu, Zain Peeran, Poojan Shukla, Jacob Young, Rohit Gupta, Jasper Wu, Joanna Pak, Kyounghee Seo, Tomoko Ozawa, Brian Na, Alyssa Reddy, Steve Braunstein, …
• SURG-21. DEVELOPMENT AND VALIDATION OF A CLINICAL RISK SCORE FOR POSTOPERATIVE OUTCOME IN NEWLY DIAGNOSED GLIOBLASTOMA: A REPORT OF THE RANORESECT GROUP.
  Neuro-Oncology 2024 Philipp Karschnia, Jacob S Young, Gilbert C Youssef, Antonio Dono, Levin Häni, Tommaso Sciortino, Francesco Bruno, Stephanie T Juenger, Nico Teske, Jorg Dietrich, Michael Weller, Michael A Vogelbaum, …
• SURG-24. MAXIMAL SAFE RESECTION OF INSULAR GLIOMAS: AN EVALUATION OF SURGICAL AND PROGNOSTIC OUTCOMES IN 461 CASES.
  Neuro-Oncology 2024 Nadeem N Al-Adli, Jacob S Young, Jing Li, Daniel Quintana, Abraham Dada, Grazia Menna, Jasper K W Gerritsen, Ramin A Morshed, Shawn L Hervey-Jumper, Mitchel S Berger
• P18.54.B DEVELOPMENT AND VALIDATION OF A CLINICAL RISK SCORE FOR POSTOPERATIVE OUTCOME IN NEWLY DIAGNOSED GLIOBLASTOMA: A REPORT OF THE RANO RESECT GROUP.
  Neuro-Oncology 2024 P Karschnia, J S Young, G C Youssef, A Dono, L Häni, T Sciortino, F Bruno, S T Juenger, N Teske, J Dietrich, M Weller, M A Vogelbaum, M van den Bent, J Beck, N Thon, J K Gerritsen, S Hervey-Jumper, D …
• Reporting standards in randomized controlled trials involving neuro-oncology caregivers: A systematic review report from the RANO-Cares working group.
  Neuro-oncology practice 2024 Boele FW, Hertler C, Sherwood P, Cachia D, Dirven L, Young JS, Walbert T, Stockdill M, Rodriguez Almaraz E, Piil K
• Resection versus biopsy in patients with glioblastoma (RESBIOP study): study protocol for an international multicentre prospective cohort study (ENCRAM 2202).
  BMJ open 2024 Gerritsen JKW, Young JS, Krieg SM, Jungk C, Ille S, Schucht P, Nahed BV, Broekman MLD, Berger M, De Vleeschouwer S, Vincent AJPE
• Glioblastoma induces the recruitment and differentiation of dendritic-like "hybrid" neutrophils from skull bone marrow.
  Cancer cell 2024 Lad M, Beniwal AS, Jain S, Shukla P, Kalistratova V, Jung J, Shah SS, Yagnik G, Saha A, Sati A, Babikir H, Nguyen AT, Gill S, Rios J, Young JS, Lui A, Salha D, Diaz A, Aghi MK
• MerlinS13 phosphorylation regulates meningioma Wnt signaling and magnetic resonance imaging features.
  Nature communications 2024 Eaton CD, Avalos L, Liu SJ, Chen Z, Zakimi N, Casey-Clyde T, Bisignano P, Lucas CG, Stevenson E, Choudhury A, Vasudevan HN, Magill ST, Young JS, Krogan NJ, Villanueva-Meyer JE, Swaney DL, Raleigh DR
• Interventional neurorehabilitation for glioma patients: A systematic review.
  Neuro-oncology practice 2024 Ekert JO, Goyal A, Young JS, Hervey-Jumper SL, Berger MS
• Development and validation of a clinical risk score for postoperative outcome in newly diagnosed glioblastoma: A report of the RANO Resect group.
  Journal of Clinical Oncology 2024 Philipp Karschnia, Jacob S Young, Antonio Dono, Levin Häni, Stephanie T. Jünger, Tommaso Sciortino, Nico Teske, Gilbert Youssef, Francesco Bruno, Michael A. Vogelbaum, Roberta Rudà, Raymond Yi-kun …
• SUPRAMAX-study: supramaximal resection versus maximal resection for glioblastoma patients: study protocol for an international multicentre prospective cohort study (ENCRAM 2201).
  BMJ open 2024 Gerritsen JKW, Young JS, Chang SM, Krieg SM, Jungk C, van den Bent MJ, Satoer DD, Ille S, Schucht P, Nahed BV, Broekman MLD, Berger M, De Vleeschouwer S, Vincent AJPE
• Strategies to Improve Drug Delivery Across the Blood-Brain Barrier for Glioblastoma.
  Current neurology and neuroscience reports 2024 Narsinh KH, Perez E, Haddad AF, Young JS, Savastano L, Villanueva-Meyer JE, Winkler E, de Groot J
• 1236 Skull-Derived Myeloid Cells Augment T Cell Responses and Suppress Glioblastoma Growth.
  Neurosurgery 2024 Meeki Lad, Jacob Young, Austin Lui, Diana Salha, Manish Kumar Aghi
• Prognostic Evaluation of Surgical Re-Resection for Recurrent Glioblastoma Using the Novel RANO Classification for Extent of Resection by The RANO Resect Group.
  Neurosurgery 2024 Philipp Karschnia, Antonio Gabriel Dono Ostorga, Jacob Young, Stephanie T. Jünger, Nico Teske, Levin Häni, Tommaso Sciortino, Christine Y. Mau, Francesco Bruno, Luis C. Nunez, Michael Weller, Martin …
• Skull-Derived Myeloid Cells Augment T Cell Responses and Suppress Glioblastoma Growth.
  Neurosurgery 2024 Meeki Lad, Jacob Young, Diana Salha, Austin Lui, Manish Kumar Aghi
• Targeted DNA Sequencing Reveals Molecular Factors Associated with Clinical Outcomes in Recurrent Glioblastoma.
  Neurosurgery 2024 Nadeem Al-Adli, William Chen, Jacob Young, Kanish Mirchia, Zain Peeran, Steve Braunstein, Arie Perry, John de Groot, David R. Raleigh, Joseph Costello, Mitchel Berger, Harish Vasudevan
• Associations between recurrence patterns and outcome in glioblastoma patients undergoing re-resection: A complementary report of the RANO resect group.
  Neuro-oncology 2024 Karschnia P, Dono A, Young JS, Juenger ST, Teske N, Häni L, Sciortino T, Mau CY, Bruno F, Nunez L, Morshed RA, Haddad AF, Weller M, van den Bent M, Thon N, Beck J, Hervey-Jumper S, Molinaro AM, Tandon…
• The importance of considering competing risks in recurrence analysis of intracranial meningioma.
  Journal of neuro-oncology 2024 Mirian C, Jensen LR, Juratli TA, Maier AD, Torp SH, Shih HA, Morshed RA, Young JS, Magill ST, Bertero L, Stummer W, Spille DC, Brokinkel B, Oya S, Miyawaki S, Saito N, Proescholdt M, Kuroi Y, Gousias …
• A Comparison of the Volumetric Growth Rate of Nonfunctional Pituitary Microadenomas Versus Macroadenomas.
  Journal of Neurological Surgery Part B Skull Base 2024 Zain Peeran, Tej Tummala, Edward Fisher, Elaina Wang, Jacob Young, Robert C. Osorio, Manish K. Aghi
• Prognostic Value of Immediate Postoperative Prolactin following Prolactinoma Resection on Long-Term Remission of Hyperprolactinemia.
  Journal of Neurological Surgery Part B Skull Base 2024 Zain Peeran, Tej Tummala, Chris Kourkoulakos, Jacob Young, Austin Lui, Aarav Badani, Harmon Khela, Aymen Kabir, Robert C. Osorio, Manish K. Aghi
• Glioma-Immune Cell Crosstalk in Tumor Progression.
  Cancers 2024 Elguindy M, Young JS, Mondal I, Lu RO, Ho WS
• Surgical management and outcome of newly diagnosed glioblastoma without contrast enhancement (low-grade appearance): a report of the RANO resect group.
  Neuro-oncology 2024 Karschnia P, Dietrich J, Bruno F, Dono A, Juenger ST, Teske N, Young JS, Sciortino T, Häni L, van den Bent M, Weller M, Vogelbaum MA, Morshed RA, Haddad AF, Molinaro AM, Tandon N, Beck J, Schnell O, …
• "De novo replication repair deficient glioblastoma, IDH-wildtype" is a distinct glioblastoma subtype in adults that may benefit from immune checkpoint blockade.
  Acta neuropathologica 2023 Hadad S, Gupta R, Oberheim Bush NA, Taylor JW, Villanueva-Meyer JE, Young JS, Wu J, Ravindranathan A, Zhang Y, Warrier G, McCoy L, Shai A, Pekmezci M, Perry A, Bollen AW, Phillips JJ, Braunstein SE, …
• The surgical management of diffuse gliomas: Current state of neurosurgical management and future directions.
  Neuro-oncology 2023 Young JS, Morshed RA, Hervey-Jumper SL, Berger MS
• Advances in Intraoperative Glioma Tissue Sampling and Infiltration Assessment.
  Brain sciences 2023 Al-Adli NN, Young JS, Scotford K, Sibih YE, Payne J, Berger MS
• BIOM-31. TARGETED DNA SEQUENCING OF RECURRENT GLIOBLASTOMA IDENTIFIES MOLECULAR FACTORS ASSOCIATED WITH CLINICAL OUTCOMES.
  Neuro-Oncology 2023 Nadeem Al-Adli, William Chen, Jacob Young, Kanish Mirchia, Zain Peeran, Steve Braunstein, Arie Perry, John de Groot, David Raleigh, Joseph Costello, Mitchel Berger, Harish Vasudevan
• CNSC-06. REDIRECTING IMMUNOSUPPRESSIVE GLIOMA MICROENVIRONMENT THROUGH PHARMACOLOGICAL INTERVENTION TARGETING NEURONAL ACTIVITY.
  Neuro-Oncology 2023 Takahide Nejo, Saritha Krishna, Akane Yamamichi, Christian Jimenez, Senthilnath Lakshmanachetty, Jacob Young, Su Phyu, Payal Watchmaker, Shawn Hervey-Jumper, Hideho Okada
• EPCO-28. MULTIPLATFORM MOLECULAR AND FUNCTIONAL GENOMIC ANALYSES OF NF1 MUTANT GLIOBLASTOMA IDENTIFY DISTINCT CO-MUTATION PATTERNS AND DRUGGABLE DEPENDENCIES UNDERLYING SELUMETINIB RESPONSE.
  Neuro-Oncology 2023 Kanish Mirchia, Emily Payne, Sixuan Pan, Nadeem Al-Adli, Jacob Young, William Chen, Joanna Pak, Kyounghee Seo, Tomoko Ozawa, Alyssa T Reddy, Arie Perry, John Liu, Mitchel Berger, David Raleigh, Harish…
• EXTH-34. LOCAL DELIVERY OF AN IL-15 SUPERAGONIST USING A REPLICATING RETROVIRUS SYNGERIZES WITH TEMOZOLOMIDE TO INCREASE LYMPHOCYTE INFILTRATION AND SURVIVAL IN TWO POORLY IMMUNOGENIC GLIOBLASTOMA MOUSE MODELS.
  Neuro-Oncology 2023 Alexander F Haddad, Jordan Spatz, Atul Saha, Megan Montoya, Sara Collins, Sabraj Gill, Elaina Wang, Pavlina Chuntova, Diana Salha, Jacob Young, Noriyuki Kasahara, Manish Aghi
• EXTH-68. SYSTEMIC NEUTRALIZATION OF IL6 SENSITIZES IDH-WILDTYPE GLIOBLASTOMA PRECLINICAL MODELS TO IMMUNE CHECKPOINT INHIBITION.
  Neuro-Oncology 2023 Jacob Young, Nam Woo Cho, Calixto-Hope Lucas, Kanish Mirchia, Kyounghee Seo, William Chen, Minh Nguyen, Arya Chen, Joanna Phillips, Tomoko Ozawa, Aparna Bhaduri, Manish Aghi, Joseph DeRisi, Mitchel …
• IMMU-04. LOW-INTENSITY PULSED ULTRASOUND ENHANCES CAR T CELL THERAPY BY INDUCING TWO-WAY IMMUNE CELL TRAFFICKING – T CELL INTO TUMOR AND MYELOID CELL INTO PERIPHERY IN A SYNGENEIC MOUSE GLIOBLASTOMA MODEL.
  Neuro-Oncology 2023 Akane Yamamichi, Tiffany Chen, Su Phyu, Jacob Young, Keith Kyewarabye, Ryusuke Hatae, Marco Gallus, Michael Canney, Adam Sonabend, Hideho Okada
• PATH-40. “DE NOVO REPLICATION REPAIR DEFICIENT GLIOBLASTOMA, IDH-WILDTYPE” IS A DISTINCT GLIOBLASTOMA SUBTYPE IN ADULTS THAT MAY BENEFIT FROM IMMUNE CHECKPOINT BLOCKADE.
  Neuro-Oncology 2023 Sara Hadad, Nancy Ann Oberheim Bush, Jennifer Clarke, Jennie Taylor, Jacob Young, Javier Villanueva-Meyer, Yalan Zhang, Rohit Gupta, Jasper Wu, Ajay Ravindranathan, Shawn Hervey-Jumper, Susan Chang, …
• TMIC-34. SKULL-DERIVED MYELOID CELLS AUGMENT T CELL RESPONSES AND SUPPRESS GLIOBLASTOMA GROWTH.
  Neuro-Oncology 2023 Meeki Lad, Venina Kalistratova, Jacob Young, Sabraj Gill, Atul Saha, Jennifer Rios, Diana Salha, Austin Lui, Manish Aghi
• Targeted gene expression profiling predicts meningioma outcomes and radiotherapy responses.
  Nature medicine 2023 Chen WC, Choudhury A, Youngblood MW, Polley MC, Lucas CG, Mirchia K, Maas SLN, Suwala AK, Won M, Bayley JC, Harmanci AS, Harmanci AO, Klisch TJ, Nguyen MP, Vasudevan HN, McCortney K, Yu TJ, Bhave V, …
• Insular Gliomas: A Review of Surgical Anatomy and Operative Considerations.
  Functional Anatomy of the Brain: A View from the Surgeon’s Eye 2023 Ramin A. Morshed, Jacob S. Young, Alexander F. Haddad, Mitchel S. Berger
• Asleep triple-modality motor mapping for perirolandic gliomas: an update on outcomes.
  Journal of neurosurgery 2023 Morshed RA, Cummins DD, Clark JP, Young JS, Haddad AF, Gogos AJ, Hervey-Jumper SL, Berger MS
• Adjuvant Chemoradiotherapy within One Year of Resection for Molecularly Defined Astrocytoma.
  International Journal of Radiation Oncology • Biology • Physics 2023 S.J. Liu, W.C. Chen, Y. Zhang, J.S. Young, R.A. Morshed, M.P. Nguyen, J. Villanueva-Meyer, J. Phillips, N.A. Oberheim, M.K. Aghi, P.K. Sneed, S.E. Braunstein, J. de Groot, M.S. Berger, A.M. Molinaro, …
• JS05.7.A SURGICAL RE-RESECTION FOR RECURRENT GLIOBLASTOMA: PROGNOSTIC EVALUATION USING THE NOVEL RANO CLASSIFICATION FOR EXTENT OF RESECTION FROM THE RANORESECT GROUP.
  Neuro-Oncology 2023 P Karschnia, A Dono, J S Young, S T Juenger, N Teske, L Häni, T Sciortino, C Y Mau, F Bruno, L Nunez, R A Morshed, A F Haddad, M Weller, M van den Bent, J Beck, S Hervey-Jumper, A M Molinaro, N Tandon…
• Prognostic evaluation of re-resection for recurrent glioblastoma using the novel RANO classification for extent of resection: A report of the RANO resect group.
  Neuro-oncology 2023 Karschnia P, Dono A, Young JS, Juenger ST, Teske N, Häni L, Sciortino T, Mau CY, Bruno F, Nunez L, Morshed RA, Haddad AF, Weller M, van den Bent M, Beck J, Hervey-Jumper S, Molinaro AM, Tandon N, Rudà…
• Glioma-neuronal circuit remodeling induces regional immunosuppression.
  bioRxiv : the preprint server for biology 2023 Nejo T, Krishna S, Jimenez C, Yamamichi A, Young JS, Lakshmanachetty S, Chen T, Phyu SSS, Ogino H, Watchmaker P, Diebold D, Choudhury A, Daniel AGS, Raleigh DR, Hervey-Jumper SL, Okada H
• Analysis of upfront resection or stereotactic radiosurgery for local control of solid and cystic cerebellar hemangioblastomas.
  Journal of neurosurgery 2023 Carrete LR, Morshed RA, Young JS, Avalos LN, Sneed PK, Aghi MK, McDermott MW, Theodosopoulos PV
• Molecular Features of Resected Melanoma Brain Metastases, Clinical Outcomes, and Responses to Immunotherapy.
  JAMA network open 2023 Vasudevan HN, Delley C, Chen WC, Mirchia K, Pan S, Shukla P, Aabedi AA, Nguyen MP, Morshed RA, Young JS, Boreta L, Fogh SE, Nakamura JL, Theodosopoulos PV, Phillips J, Hervey-Jumper SL, Daras M, Pike …
• High-volume facilities are not always low risk: comparing risk-standardized mortality rates versus facility volume as quality measures in surgical neuro-oncology.
  Journal of neurosurgery 2023 Chalif EJ, Young JS, Villa GR, Aghi MK, Lenzi J, Berger MS
• Does waiting for surgery matter? How time from diagnostic MRI to resection affects outcomes in newly diagnosed glioblastoma.
  Journal of neurosurgery 2023 Young JS, Al-Adli NN, Muster R, Chandra A, Morshed RA, Pereira MP, Chalif EJ, Hervey-Jumper SL, Theodosopoulos PV, McDermott MW, Berger MS, Aghi MK
• Prognostic evaluation of surgical re-resection for recurrent glioblastoma using the novel RANO classification for extent of resection: A report of the RANO resect group.
  Journal of Clinical Oncology 2023 Philipp Karschnia, Antonio Dono, Jacob S Young, Stephanie T. Jünger, Nico Teske, Levin Häni, Tommaso Sciortino, Christine Y. Mau, Francesco Bruno, Michael Weller, Roberta Ruda, Michael A. Vogelbaum, …
• Prognostic validation of a new classification system for extent of resection in glioblastoma: A report of the RANO resect group.
  Neuro-oncology 2023 Karschnia P, Young JS, Dono A, Häni L, Sciortino T, Bruno F, Juenger ST, Teske N, Morshed RA, Haddad AF, Zhang Y, Stoecklein S, Weller M, Vogelbaum MA, Beck J, Tandon N, Hervey-Jumper S, Molinaro AM, …
• Technical Aspects of Motor and Language Mapping in Glioma Patients.
  Cancers 2023 Al-Adli NN, Young JS, Sibih YE, Berger MS
• A Preoperative Scoring System to Predict Function-Based Resection Limitation Due to Insufficient Participation During Awake Surgery.
  Neurosurgery 2023 Elia A, Young JS, Simboli GA, Roux A, Moiraghi A, Trancart B, Al-Adli N, Aboubakr O, Bedioui A, Leclerc A, Planet M, Parraga E, Benevello C, Oppenheim C, Chretien F, Dezamis E, Berger MS, Zanello M, …
• Abstract 2497: Glioma-induced neuronal remodeling promotes regional immunosuppression.
  Cancer Research 2023 Takahide Nejo, Saritha Krishna, Christian Jimenez, Akane Yamamichi, Jacob S. Young, Tiffany Chen, Senthilnath Lakshmanachetty, Payal Watchmaker, Abrar Choudhury, Hirokazu Ogino, David R. Raleigh, …
• 870 Association of MGMT Methylation With Response to Chemotherapy in WHO Grade 2 Low Grade Glioma.
  Neurosurgery 2023 Eric Chalif, Jacob Young, Manish Kumar Aghi
• 880 Electrophysiological Patterns of Glioma-Induced Neuronal Network Remodeling are a General Property of Brain Tumors Regardless of Subtype.
  Neurosurgery 2023 Alexander Arash Aabedi, Benjamin Lipkin, Jacob Young, Leighton Hinkley, Anne Findlay, Andy Daniel, Saritha Krishna, Gray Umbach, Akhil Surapaneni, Jasleen Kaur, Mitchel Berger, Annette Molinaro, David…
• 885 Reprogramming the Glioblastoma Immune Microenvironment With Convection Enhanced Gene Therapy Reveals Intratumor IL6 Drives Glioblastoma Immunosuppression and Growth.
  Neurosurgery 2023 Jacob Young, Nam Woo Cho, Calixto-Hope Lucas, Kyounghee Seo, Raquel Santos, S. John Liu, Joanna Phillips, Tomoko Ozawa, Aparna Bhaduri, Manish Kumar Aghi, Mitchel Berger, David R. Raleigh
• 886 Stereotactic Radiosurgery Reprograms Macrophage, Microglia, and T Cell Populations in the Glioblastoma Immune Microenvironment.
  Neurosurgery 2023 Jacob Young, Nam Woo Cho, Calixto-Hope Lucas, Kyounghee Seo, Raquel Santos, Joanna Phillips, Tomoko Ozawa, Mitchel Berger, David R. Raleigh
• Glioblastoma induces the recruitment and differentiation of hybrid neutrophils from skull bone marrow.
  bioRxiv : the preprint server for biology 2023 Lad BM, Beniwal AS, Jain S, Shukla P, Jung J, Shah SS, Yagnik G, Babikir H, Nguyen AT, Gill S, Young JS, Lui A, Salha D, Diaz A, Aghi MK
• Pseudoprogression versus true progression in glioblastoma: what neurosurgeons need to know.
  Journal of neurosurgery 2023 Young JS, Al-Adli N, Scotford K, Cha S, Berger MS
• Clinical Characteristics and Outcomes of Thyroid Stimulating Hormone-Secreting Adenomas.
  Journal of Neurological Surgery Part B Skull Base 2023 Zain Peeran, Jacob S. Young, Harmon Khela, Aarav Badani, Robert C. Osorio, Manish K. Aghi
• Functional Gonadotroph Adenomas: A Single-Institution Case Series.
  Journal of Neurological Surgery Part B Skull Base 2023 Zain Peeran, Jacob S. Young, Aarav Badani, Robert C. Osorio, Manish K. Aghi
• Pituitary Hyperplasia: A Case Series of 23 Observed and 4 Surgical Patients.
  Journal of Neurological Surgery Part B Skull Base 2023 Zain Peeran, William Carson, Jacob S. Young, Robert C. Osorio, Manish K. Aghi
• CDKN2A/B co-deletion is associated with increased risk of local and distant intracranial recurrence after surgical resection of brain metastases.
  Neuro-oncology advances 2023 Morshed RA, Nguyen MP, Cummins DD, Saggi S, Young JS, Haddad AF, Goldschmidt E, Chang EF, McDermott MW, Berger MS, Theodosopoulos PV, Hervey-Jumper SL, Daras M, Aghi MK
• Identification of risk factors associated with leptomeningeal disease after resection of brain metastases.
  Journal of neurosurgery 2023 Morshed RA, Saggi S, Cummins DD, Molinaro AM, Young JS, Viner JA, Villanueva-Meyer JE, Goldschmidt E, Boreta L, Braunstein SE, Chang EF, McDermott MW, Berger MS, Theodosopoulos PV, Hervey-Jumper SL, …
• Interactive Effects of Molecular, Therapeutic, and Patient Factors on Outcome of Diffuse Low-Grade Glioma.
  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2023 Hervey-Jumper SL, Zhang Y, Phillips JJ, Morshed RA, Young JS, McCoy L, Lafontaine M, Luks T, Ammanuel S, Kakaizada S, Egladyous A, Gogos A, Villanueva-Meyer J, Shai A, Warrier G, Rice T, Crane J, …
• Recent advances in the molecular prognostication of meningiomas.
  Frontiers in oncology 2023 Wang EJ, Haddad AF, Young JS, Morshed RA, Wu JPH, Salha DM, Butowski N, Aghi MK
• Evaluation Of Surgical Resection for Recurrent Glioblastoma Using The RANO Classification For Extent Of Resection: A Report Of The RANO Resect Group.
  Brain and Spine 2023 Philipp Karschnia, Antonio Dono, Jacob S. Young, Stephanie T. Jünger, Nico Teske, Levin Häni, Tommaso Sciortino, Christine Y. Mau, Francesco Bruno, Michael Weller, Roberta Rudà, Michael A. Vogelbaum, …
• BIOM-02. MUTATIONAL ANALYSIS AND SINGLE CELL SEQUENCING OF MELANOMA BRAIN METASTASES REVEALS BRAF STATUS CORRELATES WITH CLINICAL OUTCOME AND DIFFERENTIAL IMMUNE POPULATIONS.
  Neuro-Oncology 2022 Harish Vasudevan, Cyrille Delley, Alexander Aabedi, Poojan Shukla, Minh Nguyen, Ramin A Morshed, Jacob S Young, Ben Demaree, Devan Diwanji, Shawn L Hervey-Jumper, Lauren Boreta, Shannon Fogh, Jean …
• BIOM-31. TEMPOROSPATIAL PROTEIN PROFILING OF HUMAN GLIOBLASTOMAS REVEALS MOLECULAR MECHANISMS AND BIOMARKERS UNDERLYING RESPONSES TO IMMUNE CHECKPOINT INHIBITION.
  Neuro-Oncology 2022 Jacob S Young, Calixto-Hope Lucas, Kyounghee Seo, Minh Nguyen, William Chen, David A Solomon, Mitchel S Berger, Joanna J Phillips, Manish Aghi, David Raleigh
• CNSC-05. ELECTROPHYSIOLOGICAL PATTERNS OF GLIOMA-INDUCED NEURONAL NETWORK REMODELING ARE CONSERVED ACROSS TUMOR SUBTYPE.
  Neuro-Oncology 2022 Alexander Aabedi, Benjamin Lipkin, Jacob S Young, Leighton Hinkley, Anne Findlay, Andy Daniel, Saritha Krishna, Gray Umbach, Jasleen Kaur, Mitchel S Berger, Annette Molinaro, David Brang, Srikantan …
• CNSC-19. GLIOMA-INDUCED NEURONAL REMODELING PROMOTES REGIONAL IMMUNOSUPPRESSION.
  Neuro-Oncology 2022 Takahide Nejo, Saritha Krishna, Jacob S Young, Akane Yamamichi, Christian Jimenez, Tiffany Chen, Payal Watchmaker, Abrar Choudhury, David Diebold, Hirokazu Ogino, David Raleigh, Shawn L Hervey-Jumper,…
• RBIO-04. STEREOTACTIC RADIOSURGERY REPROGRAMS MACROPHAGE, MICROGLIA, AND CD8+ T CELL POPULATIONS IN THE GLIOBLASTOMA IMMUNE MICROENVIRONMENT.
  Neuro-Oncology 2022 Jacob S Young, Nam Woo Cho, Calixto-Hope Lucas, Kyounghee Seo, Raquel Santos, Joanna J Phillips, Tomoko Ozawa, Mitchel S Berger, David Raleigh
• SURG-04. CDK2NA/B, SMAD4, AND PIK3R1 MUTATIONS ARE ASSOCIATED WITH INCREASED RISK OF LOCAL RECURRENCE AFTER SURGICAL RESECTION OF BRAIN METASTASES.
  Neuro-Oncology 2022 Ramin A Morshed, Daniel Cummins, Minh Nguyen, Jacob S Young, Philip Theodospoulos, Shawn L Hervey-Jumper, Manish Aghi, Mariza Daras
• SURG-05. SUPERVISED MACHINE LEARNING IDENTIFIES RISK FACTORS ASSOCIATED WITH LEPTOMENINGEAL DISEASE AFTER SURGICAL RESECTION OF BRAIN METASTASES.
  Neuro-Oncology 2022 Ramin A Morshed, Satvir Saggi, Daniel Cummins, Jacob S Young, Jennifer Viner, Javier Villanueva-Meyer, Ezequiel Goldschmidt, Lauren Boreta, Steve Braunstein, Edward Chang, Michael McDermott, Mitchel S…
• TMIC-36. REPROGRAMMING THE GLIOBLASTOMA IMMUNE MICROENVIRONMENT WITH CONVECTION ENHANCED GENE THERAPY REVEALS INTRATUMOR IL6 DRIVES GLIOBLASTOMA IMMUNOSUPPRESSION AND GROWTH.
  Neuro-Oncology 2022 Jacob S Young, Nam Woo Cho, Calixto-Hope Lucas, Kyounghee Seo, Raquel Santos, S John Liu, Joanna J Phillips, Tomoko Ozawa, Aparna Bhaduri, Manish Aghi, Mitchel S Berger, David Raleigh
• Transsphenoidal Surgery for Acromegaly.
  Acromegaly 2022 Ryan R. L. Phelps, Jacob S. Young, José Gurrola, Manish K. Aghi
• Recognizing the psychological impact of a glioma diagnosis on mental and behavioral health: a systematic review of what neurosurgeons need to know.
  Journal of neurosurgery 2022 Young JS, Al-Adli N, Sibih YE, Scotford KL, Casey M, James S, Berger MS
• Mutational Analysis and Single Cell Sequencing of Melanoma Brain Metastases.
  International Journal of Radiation Oncology • Biology • Physics 2022 H. Vasudevan, C. Delley, A. Aabedi, M.P. Nguyen, R.A. Morshed, J.S. Young, B. Demaree, D. Diwanji, S. Hervey-Jumper, L. Boreta, S.E. Fogh, J.L. Nakamura, P.V. Theodosopoulos, J. Phillips, M. Daras, K.…
• Timing of Adjuvant Radiotherapy and Survival Analysis for Molecularly Defined Low Grade Glioma.
  International Journal of Radiation Oncology • Biology • Physics 2022 S.J. Liu, W.C. Chen, Y. Zhang, J.S. Young, R.A. Morshed, J. Villanueva-Meyer, J. Phillips, N.A. Oberheim, M.K. Aghi, P.K. Sneed, S.E. Braunstein, M.S. Berger, A.M. Molinaro, S. Hervey-Jumper, D. …
• Chronic convection-enhanced intratumoural delivery of chemotherapy for glioblastoma.
  The Lancet. Oncology 2022 Young JS, Aghi MK
• A case (report) for mechanistic validation of meningioma molecular therapies.
  Neuro-oncology advances 2022 Nguyen MP, Seo K, Eaton CD, Lucas CG, Chen WC, Choudhury A, Young JS, Raleigh DR
• Prospective genomically guided identification of "early/evolving" and "undersampled" IDH-wildtype glioblastoma leads to improved clinical outcomes.
  Neuro-oncology 2022 Zhang Y, Lucas CG, Young JS, Morshed RA, McCoy L, Oberheim Bush NA, Taylor JW, Daras M, Butowski NA, Villanueva-Meyer JE, Cha S, Wrensch M, Wiencke JK, Lee JC, Pekmezci M, Phillips JJ, Perry A, Bollen…
• TERT promotor status does not add prognostic information in IDH-wildtype glioblastomas fulfilling other diagnostic WHO criteria: A report of the RANO resect group.
  Neuro-oncology advances 2022 Karschnia P, Young JS, Dono A, Häni L, Juenger ST, Sciortino T, Bruno F, Teske N, Morshed RA, Haddad AF, Zhang Y, Stoecklein S, Vogelbaum MA, Beck J, Tandon N, Hervey-Jumper S, Molinaro AM, Rudà R, …
• OS07.6.A Extent of resection in glioblastoma: refinement and prognostic validation of a classification system from the RANO resect group.
  Neuro-Oncology 2022 P Karschnia, J S Young, A Dono, L Häni, T Sciortino, F Bruno, S T Jünger, N Teske, M Weller, R Rudà, L Bello, O Schnell, Y Esquenazi, S J Grau, A M Molinaro, M S Berger, S M Chang, M van den Bent, J …
• LOCL-06 SUPERVISED MACHINE LEARNING IDENTIFIES RISK FACTORS ASSOCIATED WITH LEPTOMENINGEAL DISEASE AFTER SURGICAL RESECTION OF BRAIN METASTASES.
  Neuro-Oncology Advances 2022 Ramin Morshed, Satvir Saggi, Daniel Cummins, Jacob Young, Jennifer Viner, Javier Villanueva-Meyer, Lauren Boreta, Steve Braunstein, Michael McDermott, Philip Theodosopoulos, Mitchel Berger, Shawn …
• CDK 4/6 inhibitors for the treatment of meningioma.
  Frontiers in oncology 2022 Young JS, Kidwell RL, Zheng A, Haddad AF, Aghi MK, Raleigh DR, Schulte JD, Butowski NA
• Involvement of White Matter Language Tracts in Glioma: Clinical Implications, Operative Management, and Functional Recovery After Injury.
  Frontiers in neuroscience 2022 Aabedi AA, Young JS, Chang EF, Berger MS, Hervey-Jumper SL
• Machine learning for predicting hemorrhage in pediatric patients with brain arteriovenous malformation.
  Journal of neurosurgery. Pediatrics 2022 Saggi S, Winkler EA, Ammanuel SG, Morshed RA, Garcia JH, Young JS, Semonche A, Fullerton HJ, Kim H, Cooke DL, Hetts SW, Abla A, Lawton MT, Gupta N
• A targeted gene expression biomarker and association with meningioma outcomes and radiotherapy.
  Journal of Clinical Oncology 2022 William Cheng Chen, Abrar Choudhury, Harish Vasudevan, Calixto-Hope C. Lucas, Minh P. Nguyen, Jacob S Young, Theresa Yu, Jason Chan, Nancy Ann Oberheim Bush, Jessica Schulte, Javier Villanueva-Meyer, …
• Convection-delivered adenoviral gene therapy reprograms the immunosuppressive glioblastoma microenvironment.
  Journal of Clinical Oncology 2022 Jacob S Young, Nam Woo Cho, Ti Casey-Clyde, Raquel Santos, Kyounghee Seo, Joanna J. Phillips, Mitchel S. Berger, Tomoko Ozawa, David R. Raleigh
• Prognostic validation and refinement of a classification system for extent of resection in glioblastoma: A report of the RANO resect group.
  Journal of Clinical Oncology 2022 Philipp Karschnia, Jacob S Young, Antonio Dono, Levin Häni, Tommaso Sciortino, Francesco Bruno, Stefanie T. Jünger, Nico Teske, Michael Weller, Roberta Ruda, Lorenzo Bello, Oliver Schnell, Yoshua …
• Factors associated with preoperative and postoperative seizures in patients undergoing resection of brain metastases.
  Journal of neurosurgery 2022 Garcia JH, Morshed RA, Chung J, Millares Chavez MA, Sudhakar V, Saggi S, Avalos LN, Gallagher A, Young JS, Daras M, McDermott MW, Garcia PA, Chang EF, Aghi MK
• Pituitary adenoma in the elderly: surgical outcomes and treatment trends in the United States.
  Journal of neurosurgery 2022 Chalif EJ, Morshed RA, Young JS, Haddad AF, Jain S, Aghi MK
• FLAIRectomy: Resecting beyond the Contrast Margin for Glioblastoma.
  Brain sciences 2022 Haddad AF, Young JS, Morshed RA, Berger MS
• The benefit of early surgery on overall survival in incidental low-grade glioma patients: A multicenter study.
  Neuro-oncology 2022 Ius T, Ng S, Young JS, Tomasino B, Polano M, Ben-Israel D, Kelly JJP, Skrap M, Duffau H, Berger MS
• Surgery for Control of Brain Metastases After Previous Checkpoint Inhibitor Immunotherapy.
  World neurosurgery 2022 Morshed RA, Chung JE, Cummins DD, Sudhakar V, Young JS, Daras M, Hervey-Jumper SL, Theodosopoulos PV, Aghi MK
• Resistance to immune checkpoint blockade: Mechanisms, counter-acting approaches, and future directions.
  Seminars in cancer biology 2022 Haddad AF, Young JS, Gill S, Aghi MK
• Advanced Imaging Techniques for Newly Diagnosed and Recurrent Gliomas.
  Frontiers in neuroscience 2022 Carrete LR, Young JS, Cha S
• A Transcriptomic Biomarker for Predicting Meningioma Recurrence, Survival, and Radiotherapy Response.
  Journal of Neurological Surgery Part B Skull Base 2022 William C. Chen, Abrar Choudhury, Harish N. Vasudevan, Calixto-Hope G. Lucas, Minh P. Nguyen, Jacob S. Young, Theresa Yu, Tai-CHung Lam, Jenny K. Pu, Lai-Fung Li, Gilberto K. Leung, Jason W. Chan, …
• Sarcopenia Diagnosed Using Masseter Muscle Diameter as a Survival Correlate in Elderly Patients with Glioblastoma.
  World neurosurgery 2022 Morshed RA, Young JS, Casey M, Wang EJ, Aghi MK, Berger MS, Hervey-Jumper SL
• The immunology of low-grade gliomas.
  Neurosurgical focus 2022 Haddad AF, Young JS, Oh JY, Okada H, Aghi MK
• Association of Neurological Impairment on the Relative Benefit of Maximal Extent of Resection in Chemoradiation-Treated Newly Diagnosed Isocitrate Dehydrogenase Wild-Type Glioblastoma.
  Neurosurgery 2022 Aabedi AA, Young JS, Zhang Y, Ammanuel S, Morshed RA, Dalle Ore C, Brown D, Phillips JJ, Oberheim Bush NA, Taylor JW, Butowski N, Clarke J, Chang SM, Aghi M, Molinaro AM, Berger MS, Hervey-Jumper SL
• Reducing complication rates for repeat craniotomies in glioma patients: a single-surgeon experience and comparison with the literature.
  Acta neurochirurgica 2021 Morshed RA, Young JS, Gogos AJ, Haddad AF, McMahon JT, Molinaro AM, Sudhakar V, Al-Adli N, Hervey-Jumper SL, Berger MS
• Pseudo-insular glioma syndrome: illustrative cases.
  Journal of neurosurgery. Case lessons 2021 Haddad AF, Young JS, Morshed RA, Josephson SA, Cha S, Berger MS
• Association of Neurological Impairment on the Relative Benefit of Maximal Extent of Resection in Chemoradiation-Treated Newly Diagnosed Isocitrate Dehydrogenase Wild-Type Glioblastoma.
  Neurosurgery 2021 Alexander A. Aabedi, Jacob S. Young, Yalan Zhang, Simon Ammanuel, Ramin A. Morshed, Cecilia Dalle Ore, Desmond Brown, Joanna J. Phillips, Nancy Ann Oberheim Bush, Jennie W. Taylor, Nicholas Butowski, …
• Functional outcomes after resection of middle frontal gyrus diffuse gliomas.
  Journal of neurosurgery 2021 Morshed RA, Lee AT, Wang EJ, Young JS, Cha S, Hervey-Jumper SL, Berger MS
• Functional alterations in cortical processing of speech in glioma-infiltrated cortex.
  Proceedings of the National Academy of Sciences of the United States of America 2021 Aabedi AA, Lipkin B, Kaur J, Kakaizada S, Valdivia C, Reihl S, Young JS, Lee AT, Krishna S, Berger MS, Chang EF, Brang D, Hervey-Jumper SL
• BIOM-40. TARGETED GENE EXPRESSION PROFILING PREDICTS MENINGIOMA OUTCOMES AND RADIOTHERAPY RESPONSES.
  Neuro-Oncology 2021 William Chen, Abrar Choudhury, Harish Vasudevan, Calixto Lucas, Minh Nguyen, Jacob Young, Theresa Yu, Tai-Chung Lam, Jenny Pu, Lai-Fung Li, Gilberto Leung, Jason Chan, Nancy Ann Oberheim-Bush, Javier …
• EXTH-13. LOCAL DELIVERY OF AN IL-15 SUPERAGONIST USING A REPLICATING RETROVIRUS SIGNIFICANTLY IMPROVES SURVIVAL AND LYMPHOCYTE INFILTRATION IN POORLY IMMUNOGENIC MURINE GLIOBLASTOMA MODELS.
  Neuro-Oncology 2021 Alexander Haddad, Jordan Spatz, Megan Montoya, Sara Collins, Sabraj Gill, Elaina Wang, Polly Chuntova, Jacob Young, Noriyuki Kasahara, Manish K Aghi
• SURG-08. SARCOPENIA IS A PROGNOSTIC FACTOR OF 90-DAY MORTALITY AND OVERALL SURVIVAL IN ELDERLY PATIENTS WITH GLIOBLASTOMA.
  Neuro-Oncology 2021 Ramin Morshed, Jacob Young, Megan Casey, Elaina Wang, Manish K Aghi, Mitchel Berger, Shawn Hervey-Jumper
• TAMI-66. FUNCTIONAL ALTERATIONS IN CORTICAL PROCESSING OF SPEECH IN GLIOMA-INFILTRATED CORTEX.
  Neuro-Oncology 2021 alexander Aabedi, Benjamin Lipkin, Jasleen Kaur, Sofia Kakaizada, Jacob Young, Anthony Lee, Saritha Krishna, Edward Chang, David Brang, Shawn Hervey-Jumper
• TWMP-01. RESECTION OF SUPPLEMENTARY MOTOR AREA GLIOMAS: REVISITING SUPPLEMENTARY MOTOR SYNDROME AND THE ROLE OF THE FRONTAL ASLANT TRACT.
  Neuro-Oncology 2021 Jacob Young, Andrew Gogos, Alex Aabedi, Ramin Morshed, Matheus Pereira, Samuel Lashof-Regas, Ziba Mansoori, Tracy Luks, Shawn Hervey-Jumper, Javier Villanueva-Meyer, Mitchel Berger
• Comparing the Quality of Life after Brain Injury-Overall Scale and Satisfaction with Life Scale as Outcome Measures for Traumatic Brain Injury Research.
  Journal of neurotrauma 2021 Kreitzer N, Jain S, Young JS, Sun X, Stein MB, McCrea MA, Levin HS, Giacino JT, Markowitz AJ, Manley GT, Nelson LD, Transforming Research and Clinical Knowledge in Traumatic Brain Injury (TRACK-TBI) …
• Facial pain and sensory outcomes following resection of tumors compressing the trigeminal nerve.
  Journal of neurosurgery 2021 Castro MRH, Magill ST, Morshed RA, Young JS, Braunstein SE, McDermott MW, Chang EF
• Resection of supplementary motor area gliomas: revisiting supplementary motor syndrome and the role of the frontal aslant tract.
  Journal of neurosurgery 2021 Young JS, Gogos AJ, Aabedi AA, Morshed RA, Pereira MP, Lashof-Regas S, Mansoori Z, Luks T, Hervey-Jumper SL, Villanueva-Meyer JE, Berger MS
• Comparison of Outcomes following Primary and Repeat Resection of Craniopharyngioma.
  Journal of neurological surgery. Part B, Skull base 2021 Aabedi AA, Young JS, Phelps RRL, Winkler EA, McDermott MW, Theodosopoulos PV
• Comparison of Outcomes following Primary and Repeat Resection of Craniopharyngioma.
  Journal of Neurological Surgery Part B Skull Base 2021 Alexander A. Aabedi, Jacob S. Young, Ryan R. L. Phelps, Ethan A. Winkler, Michael W. McDermott, Philip V. Theodosopoulos
• Prosopagnosia following nonlanguage dominant inferior temporal lobe low-grade glioma resection in which the inferior longitudinal fasciculus was disrupted preoperatively: illustrative case.
  2021 Jacob S. Young, Ramin A. Morshed, John P. Andrews, Soonmee Cha, Mitchel S. Berger
• Prosopagnosia following nonlanguage dominant inferior temporal lobe low-grade glioma resection in which the inferior longitudinal fasciculus was disrupted preoperatively: illustrative case.
  Journal of neurosurgery. Case lessons 2021 Young JS, Morshed RA, Andrews JP, Cha S, Berger MS
• A Review of Cortical and Subcortical Stimulation Mapping for Language.
  Neurosurgery 2021 Young JS, Lee AT, Chang EF
• SURG-11. Surgery for control of brain metastases after prior checkpoint inhibitor immunotherapy: a single-center series.
  Neuro-Oncology Advances 2021 Ramin Morshed, Jason Chung, Vivek Sudhakar, Daniel Cummins, Jacob Young, Shawn Hervey-Jumper, Philip Theodosopoulos, Manish Aghi
• Mouse Models of Glioblastoma for the Evaluation of Novel Therapeutic Strategies.
  Neuro-Oncology Advances 2021 Alexander F Haddad, Jacob S Young, Dominic Amara, Mitchel S Berger, David R Raleigh, Manish K Aghi, Nicholas A Butowski
• Mouse models of glioblastoma for the evaluation of novel therapeutic strategies.
  Neuro-oncology advances 2021 Haddad AF, Young JS, Amara D, Berger MS, Raleigh DR, Aghi MK, Butowski NA
• Clinical Pearls and Methods for Intraoperative Awake Language Mapping.
  Neurosurgery 2021 Morshed RA, Young JS, Lee AT, Berger MS, Hervey-Jumper SL
• A Neurosurgeon's Guide to Cognitive Dysfunction in Adult Glioma.
  Neurosurgery 2021 Morshed RA, Young JS, Kroliczek AA, Berger MS, Brang D, Hervey-Jumper SL
• A single institution retrospective analysis on survival based on treatment paradigms for patients with anaplastic oligodendroglioma.
  Journal of neuro-oncology 2021 Bush NAO, Young JS, Zhang Y, Dalle Ore CL, Molinaro AM, Taylor J, Clarke J, Prados M, Braunstein SE, Raleigh DR, Chang SM, Berger MS, Butowski NA
• Detection of glioma infiltration at the tumor margin using quantitative stimulated Raman scattering histology.
  Scientific reports 2021 Pekmezci M, Morshed RA, Chunduru P, Pandian B, Young J, Villanueva-Meyer JE, Tihan T, Sloan EA, Aghi MK, Molinaro AM, Berger MS, Hervey-Jumper SL
• Balancing task sensitivity with reliability for multimodal language assessments.
  Journal of neurosurgery 2021 Aabedi AA, Kakaizada S, Young JS, Ahn E, Weissman DH, Berger MS, Brang D, Hervey-Jumper SL
• Oncology and Spinal Neurosurgeons Performing Resections of Intramedullary Ependymomas Compared with Single Neurosurgeons: A 13-Year Experience at a Single Institution.
  World neurosurgery 2021 Nichols NM, Young JS, Magill ST, Morshed RA, Aabedi AA, Chou D, Mummaneni PV, McDermott MW, Theodosopoulos PV
• Letter: COVID Conundrum: Postoperative COVID-19 Infections Following Endonasal Transsphenoidal Pituitary Surgery.
  Neurosurgery 2021 Young JS, Oh T, Arora T, Blevins LS, Aghi MK, El-Sayed IH, Kunwar S, Theodosopoulos PV
• The Relationship Between Stimulation Current and Functional Site Localization During Brain Mapping.
  Neurosurgery 2021 Muster RH, Young JS, Woo PYM, Morshed RA, Warrier G, Kakaizada S, Molinaro AM, Berger MS, Hervey-Jumper SL
• Convergence of heteromodal lexical retrieval in the lateral prefrontal cortex.
  Scientific reports 2021 Aabedi AA, Kakaizada S, Young JS, Kaur J, Wiese O, Valdivia C, Krishna S, Weyer-Jamora C, Berger MS, Weissman DH, Brang D, Hervey-Jumper SL
• Commentary: Planning Brain Tumor Resection Using a Probabilistic Atlas of Cortical and Subcortical Structures Critical for Functional Processing: A Proof of Concept.
  Operative neurosurgery (Hagerstown, Md.) 2021 Morshed RA, Young JS, Hervey-Jumper SL
• Using viral vectors to deliver local immunotherapy to glioblastoma.
  Neurosurgical focus 2021 Haddad AF, Young JS, Aghi MK
• Preoperative Applications of Navigated Transcranial Magnetic Stimulation.
  Frontiers in neurology 2021 Haddad AF, Young JS, Berger MS, Tarapore PE
• Effects of ventricular entry on patient outcome during glioblastoma resection.
  Journal of neurosurgery 2021 Young JS, Gogos AJ, Pereira MP, Morshed RA, Li J, Barkovich MJ, Hervey-Jumper SL, Berger MS
• Immunologic aspects of viral therapy for glioblastoma and implications for interactions with immunotherapies.
  Journal of neuro-oncology 2021 Haddad AF, Young JS, Mummaneni NV, Kasahara N, Aghi MK
• Effects of Ventricular Entry During Glioblastoma Resection on Tumor Spread and Survival.
  Neurosurgery 2020 Jacob S Young, Andrew J Gogos, Matheus Pereira, Ramin Morshed, Matthew Barkovich, Jing Li, Shawn L Hervey-Jumper, Mitchel S Berger
• Functional Neurologic and Surgical Outcomes Among Patients Undergoing Reoperation for Craniopharyngioma Recurrence.
  Neurosurgery 2020 Alexander A Aabedi, Jacob S Young, Ryan R.L Phelps, Ethan A Winkler, Philip V Theodosopoulos
• Local Delivery of a Novel Combination Immunotherapy Increases T Cell Infiltration and Significantly Improves Survival in a Poorly Immunogenic Model of Glioblastoma.
  Neurosurgery 2020 Alexander F Haddad, Jordan Spatz, Sara Collins, Matheus P Pereira, Sabraj Gill, Megan Montoya, Pavlina Chuntova, Jacob S Young, Nikhil Mummaneni, Noriyuki Kasahara, Manish K Aghi
• Outcomes After Surgical Resection of Melanoma Brain Metastases in the Age of Checkpoint Inhibitor Treatment.
  Neurosurgery 2020 Ramin Morshed, Ramin A Morshed, Jason Chung, Vivek Sudhakar, Daniel Cummins, Jacob S Young, Mariza Daras, Manish K Aghi
• The Glioma-Network Interface: A Review of the Relationship Between Glioma Molecular Subtype and Intratumoral Function.
  Neurosurgery 2020 Jacob S Young, Ramin A Morshed, Andrew J Gogos, Dominic Amara, Javier E Villanueva-Meyer, Mitchel S Berger, Shawn L Hervey-Jumper
• The Glioma-Network Interface: A Review of the Relationship Between Glioma Molecular Subtype and Intratumoral Function.
  Neurosurgery 2020 Young JS, Morshed RA, Gogos AJ, Amara D, Villanueva-Meyer JE, Berger MS, Hervey-Jumper SL
• EXTH-17. LOCAL DELIVERY OF CYTOKINES AND SYNTHETIC IMMUNOMODULATORS INCREASES T CELL INFILTRATION AND SIGNIFICANTLY IMPROVES SURVIVAL IN A POORLY IMMUNOGENIC MODEL OF GLIOBLASTOMA.
  Neuro-Oncology 2020 Alexander Haddad, Jordan Spatz, Sara Collins, Matheus Pereira, Sabraj Gill, Megan Montoya, Polly Chuntova, Jacob Young, Nikhil Mummaneni, Noriyuki Kasahara, Manish Aghi
• PATH-37. IDENTIFYING HIGH-RISK PATIENTS FOR WHO GRADE I MENINGIOMA RECURRENCE USING HISTOPATHOLOGICAL FEATURES AND THE MIB-1 INDEX.
  Neuro-Oncology 2020 Alexander Haddad, Jacob Young, Ishan Kanungo, Sweta Sudhir, Jia-Shu Chen, David Raleigh, Stephen Magill, Michael McDermott, Manish Aghi
• SURG-07. DETECTION OF GLIOMA INFILTRATION AT THE TUMOR MARGIN USING QUANTITATIVE STIMULATED RAMAN SCATTERING MICROSCOPY.
  Neuro-Oncology 2020 Melike Pekmezci, Ramin Morshed, Pranathi Chunduru, Balaji Pandian, Jacob Young, Javier Villanueva-Meyer, Tarik Tihan, Emily Sloan, Manish Aghi, Annette Molinaro, Mitchel Berger, Shawn Hervey-Jumper
• SURG-25. EFFECT OF VENTRICULAR ENTRY DURING GLIOBLASTOMA RESECTION ON PATIENT OUTCOMES.
  Neuro-Oncology 2020 Jacob Young, Andrew Gogos, Matheus Pereira, Ramin Morshed, Jing Li, Matthew Barkovich, Shawn Hervey-Jumper, Mitchel Berger
• Functional Mapping for Glioma Surgery, Part 2: Intraoperative Mapping Tools.
  Neurosurgery clinics of North America 2020 Morshed RA, Young JS, Lee AT, Hervey-Jumper SL
• Functional Mapping for Glioma Surgery, Part 2 Intraoperative Mapping Tools.
  Neurosurgery Clinics of North America 2020 Ramin A. Morshed, Jacob S. Young, Anthony T. Lee, Shawn L. Hervey-Jumper
• Achieving efficacious immunotherapy for patients with glioblastoma.
  Expert review of anticancer therapy 2020 Young JS
• Surgical management of incidentally discovered low-grade gliomas.
  Journal of neurosurgery 2020 Gogos AJ, Young JS, Pereira MP, Morshed RA, Potts MB, Hervey-Jumper SL, Berger MS
• WHO Grade I Meningioma Recurrence: Identifying High Risk Patients Using Histopathological Features and the MIB-1 Index.
  Frontiers in oncology 2020 Haddad AF, Young JS, Kanungo I, Sudhir S, Chen JS, Raleigh DR, Magill ST, McDermott MW, Aghi MK
• Intraoperative Stereotactic Frame Registration Using a Three-Dimensional Imaging System with and without Preoperative Computed Tomography for Image Fusion.
  Stereotactic and functional neurosurgery 2020 Spatz JM, Conner AK, Young JS, Starr PA
• 12. OUTCOMES AFTER SURGICAL RESECTION OF MELANOMA BRAIN METASTASES IN THE AGE OF CHECKPOINT INHIBITOR TREATMENT.
  Neuro-Oncology Advances 2020 Ramin Morshed, Jason Chung, Vivek Sudhakar, Daniel Cummins, Jacob Young, Mariza Daras, Manish Aghi
• Triple motor mapping: transcranial, bipolar, and monopolar mapping for supratentorial glioma resection adjacent to motor pathways.
  Journal of neurosurgery 2020 Gogos AJ, Young JS, Morshed RA, Avalos LN, Noss RS, Villanueva-Meyer JE, Hervey-Jumper SL, Berger MS
• Abstract A056: A study of race and socioeconomic status impacting therapeutic clinical trial enrollment in adult gliomas patients.
  Cancer Epidemiology Biomarkers & Prevention 2020 Sheantel J Reihl, Ramin A Morshed, Sofia Kakaizada, Eric Zhang, Jacob S Young, Jennifer Clarke, Nicholas Butowski, Jennie Taylor, Nancy Ann Bush, Manish K Aghi, Mitchel S Berger, Susan Chang, Shawn L …
• Clinical characteristics and outcomes of null-cell versus silent gonadotroph adenomas in a series of 1166 pituitary adenomas from a single institution.
  Neurosurgical focus 2020 Haddad AF, Young JS, Oh T, Pereira MP, Joshi RS, Pereira KM, Osorio RC, Donohue KC, Peeran Z, Sudhir S, Jain S, Beniwal A, Chopra AS, Sandhu NS, Theodosopoulos PV, Kunwar S, El-Sayed IH, Gurrola J, …
• Molecular characteristics of diffuse lower grade gliomas: what neurosurgeons need to know.
  Acta neurochirurgica 2020 Young JS, Gogos AJ, Morshed RA, Hervey-Jumper SL, Berger MS
• A Safe Transitions Pathway for post-craniotomy neurological surgery patients: high-value care that bypasses the intensive care unit.
  Journal of neurosurgery 2020 Young JS, Chan AK, Viner JA, Sankaran S, Chan AY, Imershein S, Meary-Miller A, Theodosopoulos PV, Jacques L, Aghi MK, Chang EF, Hervey-Jumper SL, Ward T, Gibson L, Ward MM, Sanftner P, Wong S, Amara D…
• The influence of race and socioeconomic status on therapeutic clinical trial screening and enrollment.
  Journal of neuro-oncology 2020 Morshed RA, Reihl SJ, Molinaro AM, Kakaizada S, Young JS, Schulte JD, Butowski N, Taylor J, Bush NA, Aghi MK, Berger MS, Chang S, Clarke J, Hervey-Jumper SL
• Awake glioma surgery: technical evolution and nuances.
  Journal of neuro-oncology 2020 Gogos AJ, Young JS, Morshed RA, Hervey-Jumper SL, Berger MS
• The impact of high functional connectivity network hub resection on language task performance in adult low- and high-grade glioma.
  Journal of neurosurgery 2020 Lee AT, Faltermeier C, Morshed RA, Young JS, Kakaizada S, Valdivia C, Findlay AM, Tarapore PE, Nagarajan SS, Hervey-Jumper SL, Berger MS
• Association of Maximal Extent of Resection of Contrast-Enhanced and Non-Contrast-Enhanced Tumor With Survival Within Molecular Subgroups of Patients With Newly Diagnosed Glioblastoma.
  JAMA oncology 2020 Molinaro AM, Hervey-Jumper S, Morshed RA, Young J, Han SJ, Chunduru P, Zhang Y, Phillips JJ, Shai A, Lafontaine M, Crane J, Chandra A, Flanigan P, Jahangiri A, Cioffi G, Ostrom Q, Anderson JE, Badve C…
• Mesolimbic dopamine D2 receptors and neural representations of subjective value.
  Scientific reports 2019 Castrellon JJ, Young JS, Dang LC, Cowan RL, Zald DH, Samanez-Larkin GR
• ACTR-35. A STUDY OF RACE AND SOCIOECONOMIC STATUS IMPACTING THERAPEUTIC CLINICAL TRIAL ENROLLMENT IN ADULT GLIOMAS PATIENTS.
  Neuro-Oncology 2019 Ramin Morshed, Sheantel Reihl, Sofia Kakaizada, Eric Zhang, Jacob Young, Jennifer Clarke, Nicholas Butowski, Jennie Taylor, Nancy Ann Oberheim-Bush, Manish Aghi, Mitchel Berger, Susan Chang, Shawn …
• QOLP-22. DRIVERS OF COST OF SURGERY IN NEWLY-DIAGNOSED GLIOBLASTOMA PATIENTS.
  Neuro-Oncology 2019 Ankush Chandra, Jacob Young, Cecilia Dalle-Ore, Darryl Lau, Jonathan Rick, Harsh Wadhwa, Mike McDermott, Mitchel Berger, Manish Aghi
• RTHP-33. A SINGLE INSTITUTION RETROSPECTIVE ANALYSIS ON SURVIVAL BASED ON TREATMENT PARADIGMS FOR PATIENTS WITH ANAPLASTIC OLIGODENDROGLIOMA.
  Neuro-Oncology 2019 Jacob Young, Yalan Zhang, Annette Molinaro, Jennie Taylor, Jennifer Clarke, Michael Prados, Susan Chang, Mitchel Berger, Nicholas Butowski, Nancy Ann Oberheim-Bush
• SURG-14. DOES WAITING MATTER? HOW TIME FROM DIAGNOSTIC MRI TO SURGICAL RESECTION AFFECTS OUTCOMES IN NEWLY DIAGNOSED GLIOBLASTOMA.
  Neuro-Oncology 2019 Jacob Young, Rachel Muster, Ankush Chandra, Ramin Morshed, Manish Aghi
• SURG-20. IDENTIFICATION OF INFILTRATIVE CANCER CELLS AT THE GLIOMA RESECTION CAVITY MARGIN USING STIMULATED RAMAN SCATTERING MICROSCOPY.
  Neuro-Oncology 2019 Ramin Morshed, Melike Pekmezci, Jacob Young, Manish Aghi, Mike McDermott, Philip Theodosopoulos, Mitchel Berger, Shawn Hervey-Jumper
• Disruption of Frontal Aslant Tract Is Not Associated with Long-Term Postoperative Language Deficits.
  World neurosurgery 2019 Young JS, Morshed RA, Mansoori Z, Cha S, Berger MS
• Safe Transitions Pathway for Postcraniotomy Neurological Surgery Patients: High-Value Care That Bypasses the Intensive Care Unit.
  Neurosurgery 2019 Jacob S Young, Andrew Kai-Hong Chan, Jennifer Viner, Sujatha Sankaran, Alvin Y Chan, Dominic Amara, Stephen T Magill, Joseph A Osorio, Lizbeth Gibson, Peter Sanftner, Mariann Ward, Tracy Ward, Stacy …
• Management of Noncatastrophic Internal Carotid Artery Injury in Endoscopic Skull Base Surgery.
  Cureus 2019 Safaee M, Young JS, El-Sayed IH, Theodosopoulos PV
• Insurance type impacts the economic burden and survival of patients with newly diagnosed glioblastoma.
  Journal of neurosurgery 2019 Chandra A, Young JS, Dalle Ore C, Dayani F, Lau D, Wadhwa H, Rick JW, Nguyen AT, McDermott MW, Berger MS, Aghi MK
• Assessment of wakefulness during awake craniotomy to predict intraoperative language performance.
  Journal of neurosurgery 2019 Aabedi AA, Ahn E, Kakaizada S, Valdivia C, Young JS, Hervey-Jumper H, Zhang E, Sagher O, Weissman DH, Brang D, Hervey-Jumper SL
• The management of low-grade gliomas in adults.
  Journal of neurosurgical sciences 2019 Morshed RA, Young JS, Hervey-Jumper SL, Berger MS
• Delirium Risk Factors and Associated Outcomes in a Neurosurgical Cohort: A Case-Control Study.
  World neurosurgery 2019 Morshed RA, Young JS, Safaee M, Sankaran S, Berger MS, McDermott MW, Hervey-Jumper SL
• The transcortical equatorial approach for gliomas of the mesial temporal lobe: techniques and functional outcomes.
  Journal of neurosurgery 2019 Morshed RA, Young JS, Han SJ, Hervey-Jumper SL, Berger MS
• Immunotherapy for High-Grade Gliomas: A Clinical Update and Practical Considerations for Neurosurgeons.
  World neurosurgery 2019 Young JS, Dayani F, Morshed RA, Okada H, Aghi MK
• Individual Differences in Dopamine Are Associated with Reward Discounting in Clinical Groups But Not in Healthy Adults.
  The Journal of neuroscience : the official journal of the Society for Neuroscience 2018 Castrellon JJ, Seaman KL, Crawford JL, Young JS, Smith CT, Dang LC, Hsu M, Cowan RL, Zald DH, Samanez-Larkin GR
• QOLP-02. INSURANCE STATUS IMPACTS THE ECONOMIC BURDEN AND SURVIVAL OF GLIOBLASTOMA PATIENTS WITH HEALTH INSURANCE.
  Neuro-Oncology 2018 Ankush Chandra, Jacob Young, Cecilia Dalle Ore, Darryl Lau, Jonathan Rick, Fara Dayani, Alan Nguyen, Joseph Garcia, Michael McDermott, Mitchel Berger, Manish Aghi
• A Dendritic Cell-Targeted Adenoviral Vector Facilitates Adaptive Immune Response Against Human Glioma Antigen (CMV-IE) and Prolongs Survival in a Human Glioma Tumor Model.
  Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2018 Kim JW, Kane JR, Panek WK, Young JS, Rashidi A, Yu D, Kanojia D, Hasan T, Miska J, Gómez-Lim MA, Ulasov IV, Balyasnikova IV, Ahmed AU, Wainwright DA, Lesniak MS
• Perioperative outcomes following reoperation for recurrent insular gliomas.
  Journal of neurosurgery 2018 Morshed RA, Young JS, Han SJ, Hervey-Jumper SL, Berger MS
• Using genomics to guide treatment for glioblastoma.
  Pharmacogenomics 2018 Young JS, Prados MD, Butowski N
• Gene Therapy and Virotherapy of Gliomas.
  Progress in neurological surgery 2018 Kim JW, Chang AL, Kane JR, Young JS, Qiao J, Lesniak MS
• Convection-Enhanced Delivery of Polymeric Nanoparticles Encapsulating Chemotherapy in Canines with Spontaneous Supratentorial Tumors.
  World neurosurgery 2018 Young JS, Bernal G, Polster SP, Nunez L, Larsen GF, Mansour N, Podell M, Yamini B
• Sharpening the Surgeon's Knife: Value of Extent of Resection for Glioma in Molecular Age.
  World neurosurgery 2018 Morshed RA, Young JS, Hervey-Jumper SL
• Safety and outcomes of resection of butterfly glioblastoma.
  Neurosurgical focus 2018 Dayani F, Young JS, Bonte A, Chang EF, Theodosopoulos P, McDermott MW, Berger MS, Aghi MK
• Relationship between tumor location, size, and WHO grade in meningioma.
  Neurosurgical focus 2018 Magill ST, Young JS, Chae R, Aghi MK, Theodosopoulos PV, McDermott MW
• Chapter 15 Gene/Viral Treatment Approaches for Malignant Brain Cancer.
  Handbook of Brain Tumor Chemotherapy, Molecular Therapeutics, and Immunotherapy 2018 Julius W. Kim, Katarzyna C. Pituch, Annie Xiao, Jacob S. Young, Wojciech K. Panek, Megan E. Muroski, Aida Rashidi, J. Robert Kane, Deepak Kanojia, Maciej S. Lesniak
• Large-Scale Network Coupling with the Fusiform Cortex Facilitates Future Social Motivation.
  eNeuro 2017 Utevsky AV, Smith DV, Young JS, Huettel SA
• Hitting the nail on the head: combining oncolytic adenovirus-mediated virotherapy and immunomodulation for the treatment of glioma.
  Oncotarget 2017 Panek WK, Kane JR, Young JS, Rashidi A, Kim JW, Kanojia D, Lesniak MS
• Management of glioblastoma in elderly patients.
  Journal of the neurological sciences 2017 Young JS, Chmura SJ, Wainwright DA, Yamini B, Peters KB, Lukas RV
• A Comparative Study of Replication-Incompetent and -Competent Adenoviral Therapy-Mediated Immune Response in a Murine Glioma Model.
  Molecular therapy oncolytics 2017 Kim JW, Miska J, Young JS, Rashidi A, Kane JR, Panek WK, Kanojia D, Han Y, Balyasnikova IV, Lesniak MS
• P08.46 Synergistic Therapeutic Efficacy via Immunomodulatory Platelet Rich Fibrin Patch (PRF-P) in Combination with Oncolytic Adenovirus for the Treatment of Glioma.
  Neuro-Oncology 2017 W. K. Panek, Julius W. Kim, Katarzyna C. Pituch, Joshua R. Kane, Deepak Kanojia, Alex Cordero, Jason Miska, Aida Rashidi, Jacob S. Young, Maciej S. Lesniak
• 19 All Aboard Mesenchymal Stem/Stromal Cells as Cell Carriers for Virotherapy.
  Mesenchymal Stromal Cells as Tumor Stromal Modulators 2017 J.W. Kim, J. Murphy, A.L. Chang, D.A. Spencer, J.R. Kane, D. Kanojia, A. Rashidi, J.S. Young, M.S. Lesniak
• IMST-46. DENDRITIC CELL-BASED IMMUNOTHERAPY FOR MALIGNANT GLIOMA BY WAY OF A NOVEL DENDRITIC CELL-TARGETED (scFvDEC205) ADENOVIRAL VECTOR.
  Neuro-Oncology 2016 Julius W Kim, J.Robert Kane, Jacob Young, Dou Yu, Jason Miska, Alan Chang, Aida Rashidi, Atique Ahmed, Irina Balyasnikova, Maciej Lesniak
• The Impact of Traumatic Brain Injury on the Aging Brain.
  Current psychiatry reports 2016 Young JS, Hobbs JG, Bailes JE
• Single dose GLP toxicity and biodistribution study of a conditionally replicative adenovirus vector, CRAd-S-pk7, administered by intracerebral injection to Syrian hamsters.
  Journal of translational medicine 2016 Kim JW, Auffinger B, Spencer DA, Miska J, Chang AL, Kane JR, Young JS, Kanojia D, Qiao J, Mann JF, Zhang L, Wu M, Ahmed AU, Aboody KS, Strong TV, Hébert CD, Lesniak MS
• Sports-related concussions: diagnosis, complications, and current management strategies.
  Neurosurgical focus 2016 Hobbs JG, Young JS, Bailes JE
• A novel single-chain antibody redirects adenovirus to IL13Rα2-expressing brain tumors.
  Scientific reports 2015 Kim JW, Young JS, Solomaha E, Kanojia D, Lesniak MS, Balyasnikova IV
• ATPS-41DENDRITIC CELL BASED IMMUNOTHERAPY OF MALIGNANT GLIOMA VIA A NOVEL CD8a+ DC TARGETED ADENOVIRAL VECTOR.
  Neuro-Oncology 2015 Julius W. Kim, J. Robert Kane, Jacob S. Young, Dou Yu, Jason Miska, Alan L. Chang, Aida Rashidi, Atique Ahmed, Irina Balyasnikova, Maciej S. Lesniak
• A Genetically Modified Adenoviral Vector with a Phage Display-Derived Peptide Incorporated into Fiber Fibritin Chimera Prolongs Survival in Experimental Glioma.
  Human gene therapy 2015 Kim JW, Kane JR, Young JS, Chang AL, Kanojia D, Morshed RA, Miska J, Ahmed AU, Balyasnikova IV, Han Y, Zhang L, Curiel DT, Lesniak MS
• 22. A Novel Single-Chain Antibody for Selective Targeting of IL13Ra2-Expressing Brain Tumors.
  Molecular Therapy 2015 Julius W. Kim, Jacob S. Young, Maciej S. Lesniak, Irina V. Balyasnikova
• Neural stem cell-mediated delivery of oncolytic adenovirus.
  Current protocols in human genetics 2015 Kim JW, Kane JR, Young JS, Chang AL, Kanojia D, Qian S, Spencer DA, Ahmed AU, Lesniak MS
• Synchrony between sensory and cognitive networks is associated with subclinical variation in autistic traits.
  Frontiers in human neuroscience 2015 Young JS, Smith DV, Coutlee CG, Huettel SA
• Sui generis: gene therapy and delivery systems for the treatment of glioblastoma.
  Neuro-oncology 2015 Kane JR, Miska J, Young JS, Kanojia D, Kim JW, Lesniak MS
• Unlocking the promise of oncolytic virotherapy in glioma: combination with chemotherapy to enhance efficacy.
  Therapeutic delivery 2015 Spencer DA, Young JS, Kanojia D, Kim JW, Polster SP, Murphy JP, Lesniak MS
• ET-29AN OPTIMIZED ONCOLYTIC ADENOVIRUS FOR GLIOMA THERAPY: SPECIFIC TARGETING, EFFICIENT INFECTION, AND RESTRICTED REPLICATION IN GLIOMA.
  Neuro-Oncology 2014 Julius W. Kim, J. Robert Kane, Jacob S. Young, Ramin A. Morshed, Alan A. Chang, Atique U. Ahmed, Irina V. Balyasnikova, Maciej S. Lesniak
• Caudate asymmetry is related to attentional impulsivity and an objective measure of ADHD-like attentional problems in healthy adults.
  Brain structure & function 2014 Dang LC, Samanez-Larkin GR, Young JS, Cowan RL, Kessler RM, Zald DH
• Advances in stem cells, induced pluripotent stem cells, and engineered cells: delivery vehicles for anti-glioma therapy.
  Expert opinion on drug delivery 2014 Young JS, Morshed RA, Kim JW, Balyasnikova IV, Ahmed AU, Lesniak MS
• Therapeutic cell carriers: a potential road to cure glioma.
  Expert review of neurotherapeutics 2014 Young JS, Kim JW, Ahmed AU, Lesniak MS
• Radiation Dosimetry of (18)F-FPEB in Humans.
  Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2014 Kessler RM, Seibyl J, Cowan RL, Zald D, Young JS, Ansari MS, Stabin MG