Saad Megahed

Al-Azhar University, Biophysics and biomaterials, Faculty Member

University of Hamburg, Physics, Graduate Student

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Ph.D. in Physics - Biophysics, University of Hamburg.
Supervisors: Prof. Wolfgang Parak
Phone: 01117333723
Address: Egypt

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Amal Ali

National Research Centre

Dr-wasnaa Albaghdady

Univ. of Technology

Anwar Ezzat

University Of Mosul

Rereta Almeshahdy

University of Baghdad

Hanan A R Akkar

Collage Of Engineering University Of Baghdad

University of Technology/Iraq

Salem Salah Salem

Al Azhar Egypt

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Antimicrobial Effects of Ag and ZnO Nanoparticles

by Saad Megahed and mohamed El Gohary

Nanotechnology has emerged in the past decades with different disciplines including medicine that... more Nanotechnology has emerged in the past decades with different disciplines including medicine that play an important role in improvement of human health. Utilization of nanomaterials in antimicrobial application may help to avoid drawbacks of antibiotics or help to improve their antimicrobial effect against resistance of microorganisms. In the present work, silver (Ag) and zinc oxide (ZnO) nanoparticles (NPs) are synthesized and characterized using UV-Vis spectroscopy, transmission electron microscope (TEM), X-Ray diffraction (XRD), and Fourier-transform infrared spectroscopy (FT-IR). The antimicrobial activities of the synthesized ZnO and Ag NPs are carried out by well diffusion method and a microtiter method against different pathogens (Fungi, Gram-positive and Gram-negative bacteria) to reveal their minimum inhibitory concentration (MIC) and the half-maximal inhibitory concentration (IC50). The obtained results indicate that both types of nanoparticles have antimicrobial activity, while silver is more potent than ZnO NPs.

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Papers by Saad Megahed

Antimicrobial Effects of Ag and ZnO Nanoparticles

ANOTECHNOLOGY has emerged in the past decades with ……different disciplines including medicine tha... more ANOTECHNOLOGY has emerged in the past decades with ……different disciplines including medicine that plays an important role in improvement of human health. Utilization of nanomaterials in antimicrobial application may help to avoid drawbacks of antibiotics or help to improve their antimicrobial effect against resistance of microorganisms. In the present work, silver (Ag) and zinc oxide (ZnO) nanoparticles (NPs) are synthesized and characterized using UV-Vis spectroscopy, transmission electron microscope (TEM), X-Ray diffraction (XRD), and Fourier-transform infrared spectroscopy (FT-IR). The antimicrobial activities of the synthesized ZnO and Ag NPs are carried out by the well diffusion and a microtiter methods against different pathogens (Fungi, Gram-positive and Gram-negative bacteria) to reveal their minimum inhibitory concentration (MIC) and the half-maximal inhibitory concentration (IC 50). The obtained results indicate that both types of nanoparticles are bacteriostatic and bactericidal while silver is more potent than ZnO NPs. Nanotechnology, the deliberate manipulation of matter at size scales of less than 100 nm, holds the promise of creating new materials and devices that take advantage of unique phenomena realized at those dimensions, because of their high reactivity due to the large surface area to volume ratio. The Nanoparticles possess extraordinary physicochemical, optical and biological properties which can be manipulated suitably for desired applications (1). Nanosized inorganic particles, of either simple or composite nature, display unique physical and chemical properties and represent an increasingly important material in the development of novel nanodevices which can be used in numerous physical, biological, biomedical, and pharmaceutical applications (2). Silver is a safe and effective anti-bactericidal metal because it is non-toxic to animal cells and highly toxic to bacteria such as Escherchia coli (E. coli) and Staphylococcus aureas (3). Nano-silver in the form of powder as well as suspension have been used as anti-bacterial agents because they enables the loading of small quantities of silver and thus makes the product cost effective.

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Antimicrobial Effects of Ag and ZnO Nanoparticles

by Saad Megahed and mohamed El Gohary

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Antimicrobial Effects of Ag and ZnO Nanoparticles

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