Papers by Ekaette Edelduok
Nigerian Journal of Parasitology, 2021
This study was carried out to evaluate the effect of drug treatments and enzymes level on the wor... more This study was carried out to evaluate the effect of drug treatments and enzymes level on the worm burden in an experimental Schistosoma haematobium infected guinea pig. Eggs of S. haematobium were collected from the urine of infected persons and hatched into miracidia. Fresh water Snail species Bulinus truncatus were exposed to miracidia and allowed for five weeks to establish infection and develop to cercaria. Guinea pigs were exposed to S. haematobium cercaraie by subcutaneous injection. The infected guinea pigs were divided into four groups, designated as 7, 28, 90 days post infection and controls. The guinea pigs were treated singly and in combination with different doses of Praziquantel (PZQ), Artemether (ART) and Artequine (ARQ). The efficacy of the different drugs on worm burden were assessed. Blood samples were collected from the guinea pigs before and after treatment for determination of Alkaline Phosphatase (ALP), Alanine Aminotransferase (ALT) and Aspartate Aminotransfer...
Animal Research International, 2009
The study was conducted with the aim of detecting intestinal helminth infection in those living i... more The study was conducted with the aim of detecting intestinal helminth infection in those living in Lattakia Governorate, and to determine their species and prevalence through laboratory screening of stool samples for patients visiting the Microbiology Laboratory at Tishreen University Hospital -Lattakia during the years 2016 -2017. By investigating the presence of eggs in the stool samples, the results of the laboratory tests conducted on the stool samples showed a prevalence of helminth infection in the intestinal tract in the population of Lattakia. Seven species of intestinal parasitic worms were recorded due to the patients examined: 3 Species of Nematoda (Enterobius vermicularis, Ascaris lumbricoides, and Ancylostoma duodenale), and 4 Species of Platehelminthes: two species belong to the class Trematoda: Class: Paragonimus Westermani and Schistosoma mansoni, and two cases belonging to the class Cestoda: Hymenolepis nana. This study has recorded, for the first time, the infection with Ancylostoma duodenale and Schistosoma Mausoni in Syria. The overall prevalence of intestinal helminth infection was reported in patients who were referred to the Microbiology laboratory in Lattakia during the years 2016-2017 was 3.77%. The vast majority of those infected with only one species of intestinal worms, while registered two cases of infection multiplier: Ascaris lumbricoides and Enterobius Vermicularis. The study showed that Enterobius Vermicularis is the most common intestinal worms in the population in Lattakia (13.2%), followed by the Ascaris lumbricoides, then the stalagmites. The prevalence of intestinal helminth infection in Lattakia was higher among males than females, and prevalence of intestinal helminthiasis was highest in winter and autumn of 2016-2017.
The bio-insecticidal potentials of testa powder of melon, Citrullus vulgaris for reducing infesta... more The bio-insecticidal potentials of testa powder of melon, Citrullus vulgaris for reducing infestation of maize grains by the maize weevil, Sitophilus zeamais was investigated. Maize mixed with testa powder of melon, Citrullus vulgaris at the dosage rates of 0.5g, 1.0g, 1.5g, 2.0g, 2.5g and 3.0g per 50g of maize was infested with five males and five females of S. zeamais for twenty-eight days. Melon testa powder significantly reduced the oviposition and natality of S. zeamais (P 0.05). Testa powder of melon seed could therefore be used as a grain protectant in storage pest management systems. Keywords: Bio-insecticidal potentials, Citrullus vulgaris, Sitophilus zeamais, maize grains
IOSR Journal of Pharmacy and Biological Sciences, 2013
The relationship between soil-transmitted helminth infections and the knowledge and practice of p... more The relationship between soil-transmitted helminth infections and the knowledge and practice of preventive measures among school children in rural communities in Igbo-Eze South Local Government Area of Enugu State, South-Eastern Nigeria, was investigated. Stool samples were obtained from 1,296 school children (ages 4 -15 years) from six schools randomly selected from the study area. Structured epidemiological questionnaires were administered to the children. Out of 1,296 school children examined, 106 (8.1 %) of the children were infected by soil-transmitted infections thus: 64 (4.9 %) with Ascarislumbricoides, 33 (2.5 %) with hookworm, and 9 (0.7 %) with Trichuristrichiura. There were significant differences in the prevalence of these infections (P < 0.05). Soil-transmitted helminth infections showed statistically significant (P < 0.05) relationships with knowledge and practice of preventive measures among school children in the study area. The study revealed that soil-transmitted helminth infections were abundant among school children of the study area, indicating the necessity of implementing control measures such as chemotherapy, provision of adequate sanitary facilities and safe drinking water.
The relationship between soil-transmitted helminth infections and the knowledge and practice of p... more The relationship between soil-transmitted helminth infections and the knowledge and practice of preventive measures among school children in rural communities in Igbo-Eze South Local Government Area of Enugu State, South-Eastern Nigeria, was investigated. Stool samples were obtained from 1,296 school children (ages 4 -15 years) from six schools randomly selected from the study area. Structured epidemiological questionnaires were administered to the children. Out of 1,296 school children examined, 106 (8.1 %) of the children were infected by soil-transmitted infections thus: 64 (4.9 %) with Ascarislumbricoides, 33 (2.5 %) with hookworm, and 9 (0.7 %) with Trichuristrichiura. There were significant differences in the prevalence of these infections (P < 0.05). Soil-transmitted helminth infections showed statistically significant (P < 0.05) relationships with knowledge and practice of preventive measures among school children in the study area. The study revealed that soil-transmitted helminth infections were abundant among school children of the study area, indicating the necessity of implementing control measures such as chemotherapy, provision of adequate sanitary facilities and safe drinking water.
The West Indian medical journal
Plasmodium infections among school children in Igbo-Eze South Local Government of Enugu State, Ni... more Plasmodium infections among school children in Igbo-Eze South Local Government of Enugu State, Nigeria, were studied between July and December 2005. The relationship between the use of malaria control measures and the prevalence of Plasmodium infections was investigated. Blood smears were obtained from 1296 school children (ages 4-15 years) from six schools randomly sampled from the study area. Drugs were given to infected children. Epidemiological questionnaires were administered to the children. Out of 1296 school children examined, 270 (20.8%) had Plasmodium falciparum infections. The prevalence of these parasitic infections varied significantly (p &lt; 0.05) among schools, with Central School, Ovoko (30.1% P falciparum) and Community primary school, Itchi (13.9%), having the highest and lowest prevalence rates respectively. Furthermore, the prevalence of P falciparum infections also varied significantly (p &lt; 0.05) among the age groups, with age groups 4-6 (35.1%) and 10-12 (14.2%) having the highest and lowest prevalence rates respectively. Males (23.1%) had a significantly higher prevalence rate than females (18.5%). The prevalence of malaria was significantly lower among pupils using preventive measures; 5.9% among pupils using mosquito bed net as against 21.2% among those not using bed nets and 4.6% for pupils living in screened houses as against 24.1% for those not living in screened houses. The study revealed that malaria is a major public health problem among pupils in a Nigerian local community. Prevalence rates among pupils varied among location of schools, age and gender. Preventive measures favoured the use of bed nets and living in screened houses.
Plasmodium infection in man is caused by the bite of an infected female Anopheles mosquito. This ... more Plasmodium infection in man is caused by the bite of an infected female Anopheles mosquito. This results in the disease, malaria. Malaria has serious debilitating effects on man. It adversely affects man's health, strength and productivity. Here, a review of Plasmodium infection in man including the life cycle transmiss on, immunity, symptoms, diagnosis, pathology, prevention, control and treatment is given. Only by knowing about Plasmodium infection, the burden of infection on man and the prevention and control options can we understand the disease better and so be better prepare for the future management of this disease. , i
Annals of Tropical Medicine and Public Health
The impact of chemotherapy on human intestinal helminthiasis among school children in semiurban t... more The impact of chemotherapy on human intestinal helminthiasis among school children in semiurban tropical communities of )gbo-Eze South Local Government Area of Enugu State, South-Eastern Nigeria, was investigated. Materials and Methods: Stool samples were obtained from school children ages -years from six schools randomly selected from the study area. (elminth eggs were recovered from stool samples. Those infected were treated with single oral dose of mg albendazole tablets and re-examined for helminth eggs weeks posttreatment. Results: Out of school children examined, . % of the children were signi icantly P < . infected with human intestinal helminths thus:
The bio-insecticidal potentials of testa powder of melon, Citrullus vulgaris for reducing infesta... more The bio-insecticidal potentials of testa powder of melon, Citrullus vulgaris for reducing infestation of maize grains by the maize weevil, Sitophilus zeamais was investigated. Maize mixed with testa powder of melon, Citrullus vulgaris at the dosage rates of 0.5g, 1.0g, 1.5g, 2.0g, 2.5g and 3.0g per 50g of maize was infested with five males and five females of S. zeamais for twenty-eight days. Melon testa powder significantly reduced the oviposition and natality of S. zeamais (P < 0.05), but did not significantly increase the mortality (P > 0.05). Testa powder of melon seed could therefore be used as a grain protectant in storage pest management systems.
The insecticidal activity of cotyledon powder of melon (Citrullus vulgaris Schrad) against the ma... more The insecticidal activity of cotyledon powder of melon (Citrullus vulgaris Schrad) against the maize weevil (Sitophilus zeamais, Motschulsky) was evaluated. The objectives of this study were to identify the potency of cotyledon powder of melon for the treatment of stored maize infested with S. zeamais. Cotyledon powder of melon, C. vulgaris, was mixed with 50g maize grains as direct admixtures at seven different rates: 0g, 0.5g, 1.0g 1.5g, 2.0g, 2.5g and 3.0g, and infested with five males and five females of S. zeamais respectively. These were observed for twenty-eight days for natality, mortality and oviposition of S. zeamais. Melon cotyledon powder significantly reduced the natality and oviposition of S. zeamais while significantly increasing the mortality (P < 0.05). Cotyledon powder of melon seed could therefore be used as a grain protectant at the rate of 3.0g per 50g of maize to achieve complete mortality of S. zeamais, while effectively decreasing natality and oviposition of S. zeamais in storage pest management systems. This will reduce the usage of chemical pesticides, thereby reducing their adverse effects on stored products.
Prevalence of intestinal helminths infections among school children in Igbo-Eze South Local Gover... more Prevalence of intestinal helminths infections among school children in Igbo-Eze South Local Government Area, Enugu State, Nigeria were studied between July and December 2005 Significant differences (P < 0.05) were recorded among the 1,296 school chidren (ages 4 – 15) randomly sampled and examined for intestina helminthes. The prevalence of intestinal helminths varied significantly among schools sampled (P < 0.05). Central Schoo, Ovoko had the highest percent prevalence for Ascaris lumbricoides (9.3 %), hookworm (6.0 %) and Trichuris trichiura (2.3 %). The least per cent prevalence of A. lumbricoides was recorded in Community Primary School, Iheakpu-Awka (2.3 %), while the least per cent prevalence of hookworm occurred in Community Primary School 3 Itchi. T. trichiura was not recorded in community primary schools in Itchi, Unadu and Iheakpu-Awka. Similarly, the prevalence of these parasitic helminths varied signiicantly among the age groups (P < 005), with age groups 4– 6 highly infected wth A. lumbricoides (7.0 %), 13 – 15wh hookworm (3.7 %) and 7 – 9 wth T. trchiura (1.2 %). T. trchiura was absent instool sampes of 4 – 6 and 13 – 15 age groups. The prevalence of these intestinal parasites also varied significantly between the sexes with femaes having comparatively more A. lumbricoides (5.4 %), hookworm (3.2 %) and T. trichiura (0.8 %) than males. Our study indicated that intestinal helminthiasis was prevalent in the area, and as such, control measures such as chemoherapy, provision of adequate sanitary facilties and potable drinking water, improved personal hygiene andhealth educaion should be the focus of non-governmental and governmental health institutions in Nigeria.
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Papers by Ekaette Edelduok