21 September 2021
22 September 2021
- 14:30-14:45
- Welcome address
- Michele Morgante-President of AGI
- 14:45-15:30
- Opening lecture - Svante Pääbo
Neandertals and our health today
- Max Planck Institute, Germany
- Chair: A. Torroni
- 15:30-17:10
- Session 1 - Evolution in action: a genome perspective
- Chairs: V. Colonna, S. Ghirotto
- 15:30-16:00
- An organized chaos controls the genomic logic underlying adaptive morphological divergence and convergence
- Riccardo Papa
- University of Puerto Rico, Puerto Rico
- 16:00-16:30
- From genome sequences to genetic load estimates: evolutionary and conservation applications
- Giorgio Bertorelle
- Università degli studi di Ferrara, Italy
- 16:30-16:50
- The genomic dark matter of avian sex chromosomes
- Valentina Peona
- Uppsala University, Sweden
- 16:50-17:10
- The genomic landscape of sympatric parallel evolution in cichlid fishes
- Paolo Franchini
- University of Konstanz, Germany
- 17:10-17:30
- 17:30-18:10
- AGI Best PhD Thesis Award
- Chair: M. Morgante
- 17:30-17:50
- Identification of new germline variants associated with the risk of developing pancreatic cancer using genome-wide data
- Manuel Gentiluomo
- University of Pisa, Italy
- 17:50-18:10
- There and back again: the genomic wanderings of human population
- Serena Aneli
- University of Padua, Italy
23 September 2021
- 14:30-16:10
- Session 2 - Chromosomes in the XXI century
- Chairs: M. Ventura, M. Rocchi
- 14:30-15:00
- Complete Telomere-to-Telomere Chromosome Assemblies: New Insights into Genome Biology & Structure
- Karen H. Miga
- UCSC Genomics Institute, CA
- 15:00-15:30
- The structure, function, and evolution of human chromosome 8
- Glennis Logsdon
- University of Washington, WA
- 15:30-15:50
- Impact of structural variants and complex events in multiple myeloma
- Francesco Maura
- University of Miami, FL
- 15:50-16:10
- Chromosome segregation errors at the beginning of life
- Tommaso Cavazza
- Max Planck Institute, Germany
- 16:10-16:30
- 16:30-18:10
- Session 3 - Genome function and phase separation
- Chairs: I. Saggio, F. d’Adda di Fagagna
- 16:30-17:00
- RNA-mediated phase separation DNA damage response signaling
- Fabrizio d'Adda di Fagagna
- Istituto FIRC di Oncologia Molecolare, Italy
- 17:00-17:20
- RNA-binding proteins and nuclear condensates in DNA repair
- Silvia Barabino
- Università degli studi Milano Bicocca, Italy
- 17:20-17:40
- Exploring protein phase separation in living cells with RNA aptamers
- Elsa Zacco
- Istituto Italiano di Tecnologia, Italy
- 17:40-18:10
- Mechanical regulation of chromatin organization and gene expression
- G.V. Shivashankar
- Paul Scherrer Institute and ETH Zurich, Switzerland
24 September 2021
- 14:30-15:20
- 15:20-15:30
- Sponsor presentation: genes, open access journal by MDPI
- Iñigo Aristizabal
- Chair: M. Ventura
- 15:30-17:10
- Session 4 - Genome editing and its applications
- Chair: G. Perini
- 15:30-16:00
- Dissecting and engineering quantitative trait variation in plants
- Zachary Lippman
- Cold Spring Harbor Laboratory, NY
- 16:00-16:30
- CRISPR technology: evolving user-friendly into genome-friendly tools
- Anna Cereseto
- Università degli studi di Trento, Italy
- 16:30-16:50
- Precise Correction of Duchenne Muscular Dystrophy Exon Deletion Mutations by Base and Prime Editing
- Francesco Chemello
- University of Texas Southwestern, TX
- 16:50-17:10
- CRISPR gene drives and their potential to fight malaria
- Valentino Gantz
- UCSD San Diego, CA
- 17:10-17:30
- 17:30-18:15
- Closing Lecture - Feng Zhang
Harnessing Biological Diversity for Developing Programmable Therapeutics
- Broad Institute of MIT and Harvard Cambridge, MA
- Chair: M. Morgante