Keratosis follicularis spinulosa decalvans (KFSD) is a rare disease with unknown etiology. It cli... more Keratosis follicularis spinulosa decalvans (KFSD) is a rare disease with unknown etiology. It clinically presents with diffuse follicular hyperkeratosis of scalp which progress to atrophy, cicatricial alopecia, and photophobia. The lesions start in chilhood and an aggrevasion occurs after puberty by the development of scalp pustules with bacterial infection and causes both functional and cosmetic discomfort. Here, we report a Cypriot girl that diagnosed KFSD that do not have any family history.
Desmoplastic infantile gangliogliomas are very rarely encountered, large supratentorial masses, d... more Desmoplastic infantile gangliogliomas are very rarely encountered, large supratentorial masses, derived from neuroepithelial origin, which have cystic and solid components and contain cells with astrocytic and ganglionic differentiation. These tumors are benign tumors of childhood that become symptomatic when they reach giant sizes. Sixty cases of desmoplastic ganglioglioma have been reported to date. In the present study, a case of giant desmoplastic infantile ganglioglioma in a 22-month-old patient is presented, which had an aggressive radiological appearance in the midline and presented with atypical symptoms.
Background/Aim: The frequency of eosinophilic esophagitis has been rising over the last decades. ... more Background/Aim: The frequency of eosinophilic esophagitis has been rising over the last decades. It is diagnosed primarily based on symptoms and endoscopic and histopathological examination findings. Although eosinophilic esophagitis is not associated with malignancy, it remains an important condition affecting both children and adults, as it is associated with morbidity such as dysphagia, food impaction, and esophageal strictures. This study aimed to define clinical and endoscopic characteristics of adult patients diagnosed with eosinophilic esophagitis based on recently recommended histopathological criteria. Methods: This retrospective cross-sectional descriptive study included 54 adult patients (mean age: 33.6 yr, range: 16-61 yr) who underwent upper gastrointestinal system endoscopy for dyspeptic complaints (epigastric pain, reflux, dysphagia, or food impaction) and diagnosed with eosinophilic esophagitis based on the latest histopathological criteria (≥15 eosinophils per high-power field). Patients with a history of malignancy were excluded. Patients' clinical, endoscopic, and histopathological data were examined. Results: In patients diagnosed with eosinophilic esophagitis, the most common presenting complaint was dysphagia (61.1%), followed by dyspepsia (24.0%), regurgitation (16.6%), chest pain (16.6%), epigastric pain (12.9%), food impaction (11.1%), and halitosis (3.7%), without any age predilection for the complaints. White papules and linear furrow were the most frequent findings on endoscopic examination (35.1% each), followed by circular rings (24.0%), paleness (22.2%), normal endoscopic finding (20.3%), and small-caliber esophagus (11.1%). Conclusion: The diagnosis of eosinophilic esophagitis remains challenging due to considerable variations in definitions and in the relative frequencies of endoscopic findings. Therefore, we recommend combining clinical, endoscopic, and histologic criteria to establish diagnosis. The identification of standards for diagnosis in future studies is warranted.
Harran Üniversitesi Tıp Fakültesi Dergisi, Apr 1, 2007
tarihleri arasında karaciğerinde kitle bulunan 107 olguya tanı amaçlı ultrasonografi (USG) eşliği... more tarihleri arasında karaciğerinde kitle bulunan 107 olguya tanı amaçlı ultrasonografi (USG) eşliğinde ince iğne aspirasyon biopsisi (İİAB) uygulanmış, girişim sırasında elde edilen aspirat içerisindeki küçük doku fragmanları da rutin takibe alınarak her olgu için ayrıca mikrohistolojik preparat elde edilmiştir.Olguların önce sitolojik, daha sonra da mikrohistolojik preparatları incelenmiş, ve iki yöntemin önce ayrı ayrı, sonra da kombine edildiğinde karaciğer kitlelerinin tanısındaki güvenilirliği araştırılmış, spesifik tanı vermedeki başarıları belirlenmiştir. Sitolojik ve mikrohistolojik yöntemler birarada kullanıldıklarında sensitivite, spesifisite, ve genel doğruluk oranlarının % 100'e çıktığı görülmüştür. Sitolojiye mikrohistoloji de eklendiğinde bu yöntemin değeri daha da artmaktadır.Yanlızca malign-benign lezyonları ayırmakla kalmayıp uygun klinikopatolojik ve radyolojik korelasyon sağlandığında lezyonun tipini kesin olarak saptayıp hastanın daha ileri tedavi protokolünü belirlemekte ve prognozu hakkında da önemli bilgiler vermektedir.
Aims: Juvenile polyps are the most common intestinal polyps in children, but they are also found ... more Aims: Juvenile polyps are the most common intestinal polyps in children, but they are also found relatively frequently in adults. Although colonoscopy and pathologic examinations are essential for the final diagnosis of juvenile polyps, our aim is to show that ultrasound imaging can also reveal the juvenile polyps. Case Report: In a 21-year-old female patient with painless rectal bleeding and abdominal pain, blood tests showed no signs of anemia or infection, but the fecal occult blood test was found to be positive. Ultrasound imaging prior to colonoscopy revealed the juvenile polyp. The polyp was resected during colonoscopy via hot snare polypectomy and then it was pathologically diagnosed as a juvenile polyp. Conclusion: Ultrasonography is not a very common diagnostic tool for colonic polyps, but it may have the potential of revealing a colonic polyp such as a juvenile polyp. This can ease the process of diagnosis.
OBJECTIVES: The current study aims to investigate the possible role of NO distillate either for t... more OBJECTIVES: The current study aims to investigate the possible role of NO distillate either for therapeutic or for protective potential in diabetic cardiomyopathy. BACKGROUND: Protective and restorative effects of distillated Nerium oleander (NO) on the diabetes-induced electrophysiological and structural alterations were investigated. METHODS: Type 2 diabetes was induced by combination of single dose streptozotocin injection and high fat diet for four weeks. Experimental groups were designed as follows: control, diabetic, restorative-NO treated diabetic and protective-NO treated diabetic. Intracellular action potentials (AP) and contractile activities were measured form left ventricular papillary muscle strips as well as histopathological examination of heart tissue and biochemical examinations of serum were performed. RESULTS: Type 2 diabetes induced AP prolongation was prevented with both ways of NO treatments. Moreover, treatments produced nearly complete restorations of diabetes-induced depressed amplitude and altered kinetics of contractile activities. In parallel to electrophysiological parameters, both histopathological and biochemical results indicates the NO induced benefi cial effects on the diabetes related alterations. CONCLUSION: Distillated Nerium oleander (NO) can be a highly potential therapeutic or preventive agent on the diabetes induced excitation-contraction coupling alterations (Tab.
Background and Objective: Periodontitis, a chronic inflammatory disease caused by oral bacterial ... more Background and Objective: Periodontitis, a chronic inflammatory disease caused by oral bacterial infection, is considered to be a risk factor for systemic diseases including diabetes mellitus, bacterial pneumonia, hyperlipidemia and atherosclerosis. The aim of this study was to evaluate the effectiveness of melatonin against periodontal inflammation-induced multiple organ injury in rats. Material and Methods: Eighteen female Wistar albino rats were randomly divided into three groups of six rats each: control; lipopolysaccharide (LPS); and LPS + melatonin. During the experimental period (10 d) all rats in the LPS and LPS + melatonin groups were given 10 lL of LPS (from a 10 mg/mL standard solution of LPS dissolved in saline) on days 1, 3 and 5. The rats in the LPS + melatonin group were given 50 mg/kg of melatonin, daily for 10 d, starting on day 1 after the administration of LPS. All rats were killed at the end of the experimental period. Liver, kidney and lung tissues were removed for investigation by light microscopy. Results: The levels of serum aspartate aminotransferase (AST), alanine transaminase (ALT) and blood urea nitrogen (BUN) were significantly increased in the LPS group compared with the LPS + melatonin group (p < 0.05). There was no significant change in the serum creatinine levels in the groups. However, the changes in serum AST, ALT and BUN levels in the experimental groups did not correlate with changes in histological data. Both LPS and LPS + melatonin groups displayed structural features similar to those of the control group. Conclusion: The results revealed that increased serum AST, ALT and BUN levels following periodontitis are ameliorated with melatonin treatment.
Özet Ankara Onkoloji Hastanesi'nde Ocak 1992-Temmuz 1996 tarihleri arasında karaciğerinde kit... more Özet Ankara Onkoloji Hastanesi'nde Ocak 1992-Temmuz 1996 tarihleri arasında karaciğerinde kitle bulunan 107 olguya tanı amaçlı ultrasonografi (USG) eşliğinde ince iğne aspirasyon biopsisi (AB) uygulanmış, girişim sırasında elde edilen aspirat içerisindeki küçük doku fragmanları da rutin takibe alınarak her olgu için ayrıca mikrohistolojik preparat elde edilmiştir.Olguların önce sitolojik, daha sonra da mikrohistolojik preparatları incelenmiş, ve iki yöntemin önce ayrı ayrı, sonra da kombine edildiğinde karaciğer kitlelerinin tanısındaki güvenilirliği araştırılmış, spesifik tanı vermedeki başarıları belirlenmiştir. Sitolojik ve mikrohistolojik yöntemler birarada kullanıldıklarında sensitivite, spesifisite, ve genel doğruluk oranlarının % 100'e çıktığı görülmüştür. Sitolojiye mikrohistoloji de eklendiğinde bu yöntemin değeri daha da artmaktadır.Yanlızca malign-benign lezyonları ayırmakla kalmayıp uygun klinikopatolojik ve radyolojik korelasyon sağlandığında lezyonun tipini kes...
Case Report: Twenty-seven years old patient who was delivered nine months ago, was admitted to ou... more Case Report: Twenty-seven years old patient who was delivered nine months ago, was admitted to our institute with findings of deep anemia and bilateral adnexial masses. Although the clinical findings were not typical, metastatic choriocarcinoma diagnosis was ...
To investigate the causes of hypertrophy in recurrent tonsillitis with hypertrophy (RTTH). Design... more To investigate the causes of hypertrophy in recurrent tonsillitis with hypertrophy (RTTH). Design: An immunohistochemical study of recurrent tonsillitis with or without hypertrophy and adenoid tissue. Setting: Academic medical center. Patients: The study population comprised 15 patients with RTTH, 15 patients with recurrent tonsillitis (RT), 9 patients with adenoid vegetation, and 6 controls. Main Outcome Measures: The following outcome measures were investigated: follicle number and follicular area and circumference; degree of papillary arrangement and keratin cyst in crypts; fibrosis; and density of S-100 ϩ cells, CD20 ϩ cells, CD45RO ϩ cells, lymphocytes and plasma cells, and cyclin D 1 ϩ cells in surface epithelium, crypt epithelium, extrafollicular area, and follicles. Results: In the RTTH group, follicle number and follicular area and circumference, S-100 ϩ cell density in crypt and surface epithelium, and CD20 ϩ cell density in crypt epithelium were higher than in the RT group. The other
European review for medical and pharmacological sciences, 2012
Testicular torsion due to oxidative stress results in infertility and testicular damage which can... more Testicular torsion due to oxidative stress results in infertility and testicular damage which can be preventable an important health problem worldwide. The purpose of the present study was to investigate the changes of malondialdehyde (MDA), total antioxidant status (TAS), total oxidant status (TOS) levels; histopathological alterations; morphology, concentration and motilities of the sperm in post ischemic reperfused (I/R) testis tissue. Forty adult male Wistar rats were carried out and were randomized to five groups; (1) Control group, (2) Ipsilateral left testis ischemia, (3) Melatonin plus ipsilateral left testis ischemia, (4) Contralateral right testis ischemia, 5. Melatonin plus contralateral right testis ischemia. After 1 h ischemia and 24 h perfusion; MDA, TAS and TOS levels were measured, histopathological alterations were determined using by Johnsen's score (JS) and sperm morphology, concentration, motility were examined. MDA, TAS and TOS levels of the testis tissue di...
ÖZET Trikilemmal kistin neoplastik karşılığı olan prolifere trikilemmal kistler, en yaygın olarak... more ÖZET Trikilemmal kistin neoplastik karşılığı olan prolifere trikilemmal kistler, en yaygın olarak saçlı deride tek lezyon şeklinde görülür. Daha az sıklıkla da sırt ve boyunda rastlanır. Ortalama görülme yaşı 65 yaş olup kadınlarda erkeklerden 5 kat daha sık görülür. Mikroskopik olarak çevre dokudan düzenli sınırlarla ayrılan, oval, yuvarlak, veziküler nükleuslu, yer yer belirgin nükleollü, sınırları seçilebilen eozinofilik sitoplazmalı hücrelerden oluşan solid adacıkların ortalarında bol miktarda amorf keratinöz materyal izlenir. Benign lezyonlardır, fakat nadiren malign değişim gösterebilirler. 62 yaşında bir bayanda aksillada yerleşmiş prolifere trikilemmal kist, seyrek görülen bir lezyon olması ve ilginç lokalizasyonu nedeniyle, literatür bilgileri eşliğinde klinik ve histopatolojik özellikleriyle sunulmuştur. Anahtar Kelimeler: Prolifere trikilemmal kist, aksilla lokalizasyon Proliferating tichilemmal cyst: A case report ABSTRACT Proliferating trichilemmal cyst which is the neo...
Dear Editor, Referring to synovitis, acne, pustulosis, hyperostosis and osteitis; SAPHO syndrome ... more Dear Editor, Referring to synovitis, acne, pustulosis, hyperostosis and osteitis; SAPHO syndrome is defined as a chronic, relapsing rheumatologic disease of uncertain etiology characterized by distinct osteoarticular and cutaneous manifestations. There have been recent reports of chronic recurrent multifocal osteomyelitis (CRMO) occurring in adults and SAPHO syndrome occurring in children whereas just the vice-versa is normally expected[1,2]. Herein, we would like to emphasize a rare form of SAPHO syndrome in terms of age and the localization of the disease. A 12-year-old female patient was admitted to our hospital with the complaint of right hip and low back pain. She had tenderness on the right iliac crest. She had normal hemogram with an erythrocyte sedimentation rate (ESR) of 51 mm/hour. Serological tests for Salmonella and Brucella were negative. Having a BCG vaccination scar, PPD was negative and no abnormalities were found in chest radiography of the patient. Bone marrow aspi...
Keratosis follicularis spinulosa decalvans (KFSD) is a rare disease with unknown etiology. It cli... more Keratosis follicularis spinulosa decalvans (KFSD) is a rare disease with unknown etiology. It clinically presents with diffuse follicular hyperkeratosis of scalp which progress to atrophy, cicatricial alopecia, and photophobia. The lesions start in chilhood and an aggrevasion occurs after puberty by the development of scalp pustules with bacterial infection and causes both functional and cosmetic discomfort. Here, we report a Cypriot girl that diagnosed KFSD that do not have any family history.
Desmoplastic infantile gangliogliomas are very rarely encountered, large supratentorial masses, d... more Desmoplastic infantile gangliogliomas are very rarely encountered, large supratentorial masses, derived from neuroepithelial origin, which have cystic and solid components and contain cells with astrocytic and ganglionic differentiation. These tumors are benign tumors of childhood that become symptomatic when they reach giant sizes. Sixty cases of desmoplastic ganglioglioma have been reported to date. In the present study, a case of giant desmoplastic infantile ganglioglioma in a 22-month-old patient is presented, which had an aggressive radiological appearance in the midline and presented with atypical symptoms.
Background/Aim: The frequency of eosinophilic esophagitis has been rising over the last decades. ... more Background/Aim: The frequency of eosinophilic esophagitis has been rising over the last decades. It is diagnosed primarily based on symptoms and endoscopic and histopathological examination findings. Although eosinophilic esophagitis is not associated with malignancy, it remains an important condition affecting both children and adults, as it is associated with morbidity such as dysphagia, food impaction, and esophageal strictures. This study aimed to define clinical and endoscopic characteristics of adult patients diagnosed with eosinophilic esophagitis based on recently recommended histopathological criteria. Methods: This retrospective cross-sectional descriptive study included 54 adult patients (mean age: 33.6 yr, range: 16-61 yr) who underwent upper gastrointestinal system endoscopy for dyspeptic complaints (epigastric pain, reflux, dysphagia, or food impaction) and diagnosed with eosinophilic esophagitis based on the latest histopathological criteria (≥15 eosinophils per high-power field). Patients with a history of malignancy were excluded. Patients' clinical, endoscopic, and histopathological data were examined. Results: In patients diagnosed with eosinophilic esophagitis, the most common presenting complaint was dysphagia (61.1%), followed by dyspepsia (24.0%), regurgitation (16.6%), chest pain (16.6%), epigastric pain (12.9%), food impaction (11.1%), and halitosis (3.7%), without any age predilection for the complaints. White papules and linear furrow were the most frequent findings on endoscopic examination (35.1% each), followed by circular rings (24.0%), paleness (22.2%), normal endoscopic finding (20.3%), and small-caliber esophagus (11.1%). Conclusion: The diagnosis of eosinophilic esophagitis remains challenging due to considerable variations in definitions and in the relative frequencies of endoscopic findings. Therefore, we recommend combining clinical, endoscopic, and histologic criteria to establish diagnosis. The identification of standards for diagnosis in future studies is warranted.
Harran Üniversitesi Tıp Fakültesi Dergisi, Apr 1, 2007
tarihleri arasında karaciğerinde kitle bulunan 107 olguya tanı amaçlı ultrasonografi (USG) eşliği... more tarihleri arasında karaciğerinde kitle bulunan 107 olguya tanı amaçlı ultrasonografi (USG) eşliğinde ince iğne aspirasyon biopsisi (İİAB) uygulanmış, girişim sırasında elde edilen aspirat içerisindeki küçük doku fragmanları da rutin takibe alınarak her olgu için ayrıca mikrohistolojik preparat elde edilmiştir.Olguların önce sitolojik, daha sonra da mikrohistolojik preparatları incelenmiş, ve iki yöntemin önce ayrı ayrı, sonra da kombine edildiğinde karaciğer kitlelerinin tanısındaki güvenilirliği araştırılmış, spesifik tanı vermedeki başarıları belirlenmiştir. Sitolojik ve mikrohistolojik yöntemler birarada kullanıldıklarında sensitivite, spesifisite, ve genel doğruluk oranlarının % 100'e çıktığı görülmüştür. Sitolojiye mikrohistoloji de eklendiğinde bu yöntemin değeri daha da artmaktadır.Yanlızca malign-benign lezyonları ayırmakla kalmayıp uygun klinikopatolojik ve radyolojik korelasyon sağlandığında lezyonun tipini kesin olarak saptayıp hastanın daha ileri tedavi protokolünü belirlemekte ve prognozu hakkında da önemli bilgiler vermektedir.
Aims: Juvenile polyps are the most common intestinal polyps in children, but they are also found ... more Aims: Juvenile polyps are the most common intestinal polyps in children, but they are also found relatively frequently in adults. Although colonoscopy and pathologic examinations are essential for the final diagnosis of juvenile polyps, our aim is to show that ultrasound imaging can also reveal the juvenile polyps. Case Report: In a 21-year-old female patient with painless rectal bleeding and abdominal pain, blood tests showed no signs of anemia or infection, but the fecal occult blood test was found to be positive. Ultrasound imaging prior to colonoscopy revealed the juvenile polyp. The polyp was resected during colonoscopy via hot snare polypectomy and then it was pathologically diagnosed as a juvenile polyp. Conclusion: Ultrasonography is not a very common diagnostic tool for colonic polyps, but it may have the potential of revealing a colonic polyp such as a juvenile polyp. This can ease the process of diagnosis.
OBJECTIVES: The current study aims to investigate the possible role of NO distillate either for t... more OBJECTIVES: The current study aims to investigate the possible role of NO distillate either for therapeutic or for protective potential in diabetic cardiomyopathy. BACKGROUND: Protective and restorative effects of distillated Nerium oleander (NO) on the diabetes-induced electrophysiological and structural alterations were investigated. METHODS: Type 2 diabetes was induced by combination of single dose streptozotocin injection and high fat diet for four weeks. Experimental groups were designed as follows: control, diabetic, restorative-NO treated diabetic and protective-NO treated diabetic. Intracellular action potentials (AP) and contractile activities were measured form left ventricular papillary muscle strips as well as histopathological examination of heart tissue and biochemical examinations of serum were performed. RESULTS: Type 2 diabetes induced AP prolongation was prevented with both ways of NO treatments. Moreover, treatments produced nearly complete restorations of diabetes-induced depressed amplitude and altered kinetics of contractile activities. In parallel to electrophysiological parameters, both histopathological and biochemical results indicates the NO induced benefi cial effects on the diabetes related alterations. CONCLUSION: Distillated Nerium oleander (NO) can be a highly potential therapeutic or preventive agent on the diabetes induced excitation-contraction coupling alterations (Tab.
Background and Objective: Periodontitis, a chronic inflammatory disease caused by oral bacterial ... more Background and Objective: Periodontitis, a chronic inflammatory disease caused by oral bacterial infection, is considered to be a risk factor for systemic diseases including diabetes mellitus, bacterial pneumonia, hyperlipidemia and atherosclerosis. The aim of this study was to evaluate the effectiveness of melatonin against periodontal inflammation-induced multiple organ injury in rats. Material and Methods: Eighteen female Wistar albino rats were randomly divided into three groups of six rats each: control; lipopolysaccharide (LPS); and LPS + melatonin. During the experimental period (10 d) all rats in the LPS and LPS + melatonin groups were given 10 lL of LPS (from a 10 mg/mL standard solution of LPS dissolved in saline) on days 1, 3 and 5. The rats in the LPS + melatonin group were given 50 mg/kg of melatonin, daily for 10 d, starting on day 1 after the administration of LPS. All rats were killed at the end of the experimental period. Liver, kidney and lung tissues were removed for investigation by light microscopy. Results: The levels of serum aspartate aminotransferase (AST), alanine transaminase (ALT) and blood urea nitrogen (BUN) were significantly increased in the LPS group compared with the LPS + melatonin group (p < 0.05). There was no significant change in the serum creatinine levels in the groups. However, the changes in serum AST, ALT and BUN levels in the experimental groups did not correlate with changes in histological data. Both LPS and LPS + melatonin groups displayed structural features similar to those of the control group. Conclusion: The results revealed that increased serum AST, ALT and BUN levels following periodontitis are ameliorated with melatonin treatment.
Özet Ankara Onkoloji Hastanesi'nde Ocak 1992-Temmuz 1996 tarihleri arasında karaciğerinde kit... more Özet Ankara Onkoloji Hastanesi'nde Ocak 1992-Temmuz 1996 tarihleri arasında karaciğerinde kitle bulunan 107 olguya tanı amaçlı ultrasonografi (USG) eşliğinde ince iğne aspirasyon biopsisi (AB) uygulanmış, girişim sırasında elde edilen aspirat içerisindeki küçük doku fragmanları da rutin takibe alınarak her olgu için ayrıca mikrohistolojik preparat elde edilmiştir.Olguların önce sitolojik, daha sonra da mikrohistolojik preparatları incelenmiş, ve iki yöntemin önce ayrı ayrı, sonra da kombine edildiğinde karaciğer kitlelerinin tanısındaki güvenilirliği araştırılmış, spesifik tanı vermedeki başarıları belirlenmiştir. Sitolojik ve mikrohistolojik yöntemler birarada kullanıldıklarında sensitivite, spesifisite, ve genel doğruluk oranlarının % 100'e çıktığı görülmüştür. Sitolojiye mikrohistoloji de eklendiğinde bu yöntemin değeri daha da artmaktadır.Yanlızca malign-benign lezyonları ayırmakla kalmayıp uygun klinikopatolojik ve radyolojik korelasyon sağlandığında lezyonun tipini kes...
Case Report: Twenty-seven years old patient who was delivered nine months ago, was admitted to ou... more Case Report: Twenty-seven years old patient who was delivered nine months ago, was admitted to our institute with findings of deep anemia and bilateral adnexial masses. Although the clinical findings were not typical, metastatic choriocarcinoma diagnosis was ...
To investigate the causes of hypertrophy in recurrent tonsillitis with hypertrophy (RTTH). Design... more To investigate the causes of hypertrophy in recurrent tonsillitis with hypertrophy (RTTH). Design: An immunohistochemical study of recurrent tonsillitis with or without hypertrophy and adenoid tissue. Setting: Academic medical center. Patients: The study population comprised 15 patients with RTTH, 15 patients with recurrent tonsillitis (RT), 9 patients with adenoid vegetation, and 6 controls. Main Outcome Measures: The following outcome measures were investigated: follicle number and follicular area and circumference; degree of papillary arrangement and keratin cyst in crypts; fibrosis; and density of S-100 ϩ cells, CD20 ϩ cells, CD45RO ϩ cells, lymphocytes and plasma cells, and cyclin D 1 ϩ cells in surface epithelium, crypt epithelium, extrafollicular area, and follicles. Results: In the RTTH group, follicle number and follicular area and circumference, S-100 ϩ cell density in crypt and surface epithelium, and CD20 ϩ cell density in crypt epithelium were higher than in the RT group. The other
European review for medical and pharmacological sciences, 2012
Testicular torsion due to oxidative stress results in infertility and testicular damage which can... more Testicular torsion due to oxidative stress results in infertility and testicular damage which can be preventable an important health problem worldwide. The purpose of the present study was to investigate the changes of malondialdehyde (MDA), total antioxidant status (TAS), total oxidant status (TOS) levels; histopathological alterations; morphology, concentration and motilities of the sperm in post ischemic reperfused (I/R) testis tissue. Forty adult male Wistar rats were carried out and were randomized to five groups; (1) Control group, (2) Ipsilateral left testis ischemia, (3) Melatonin plus ipsilateral left testis ischemia, (4) Contralateral right testis ischemia, 5. Melatonin plus contralateral right testis ischemia. After 1 h ischemia and 24 h perfusion; MDA, TAS and TOS levels were measured, histopathological alterations were determined using by Johnsen's score (JS) and sperm morphology, concentration, motility were examined. MDA, TAS and TOS levels of the testis tissue di...
ÖZET Trikilemmal kistin neoplastik karşılığı olan prolifere trikilemmal kistler, en yaygın olarak... more ÖZET Trikilemmal kistin neoplastik karşılığı olan prolifere trikilemmal kistler, en yaygın olarak saçlı deride tek lezyon şeklinde görülür. Daha az sıklıkla da sırt ve boyunda rastlanır. Ortalama görülme yaşı 65 yaş olup kadınlarda erkeklerden 5 kat daha sık görülür. Mikroskopik olarak çevre dokudan düzenli sınırlarla ayrılan, oval, yuvarlak, veziküler nükleuslu, yer yer belirgin nükleollü, sınırları seçilebilen eozinofilik sitoplazmalı hücrelerden oluşan solid adacıkların ortalarında bol miktarda amorf keratinöz materyal izlenir. Benign lezyonlardır, fakat nadiren malign değişim gösterebilirler. 62 yaşında bir bayanda aksillada yerleşmiş prolifere trikilemmal kist, seyrek görülen bir lezyon olması ve ilginç lokalizasyonu nedeniyle, literatür bilgileri eşliğinde klinik ve histopatolojik özellikleriyle sunulmuştur. Anahtar Kelimeler: Prolifere trikilemmal kist, aksilla lokalizasyon Proliferating tichilemmal cyst: A case report ABSTRACT Proliferating trichilemmal cyst which is the neo...
Dear Editor, Referring to synovitis, acne, pustulosis, hyperostosis and osteitis; SAPHO syndrome ... more Dear Editor, Referring to synovitis, acne, pustulosis, hyperostosis and osteitis; SAPHO syndrome is defined as a chronic, relapsing rheumatologic disease of uncertain etiology characterized by distinct osteoarticular and cutaneous manifestations. There have been recent reports of chronic recurrent multifocal osteomyelitis (CRMO) occurring in adults and SAPHO syndrome occurring in children whereas just the vice-versa is normally expected[1,2]. Herein, we would like to emphasize a rare form of SAPHO syndrome in terms of age and the localization of the disease. A 12-year-old female patient was admitted to our hospital with the complaint of right hip and low back pain. She had tenderness on the right iliac crest. She had normal hemogram with an erythrocyte sedimentation rate (ESR) of 51 mm/hour. Serological tests for Salmonella and Brucella were negative. Having a BCG vaccination scar, PPD was negative and no abnormalities were found in chest radiography of the patient. Bone marrow aspi...
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